المؤلفون: Soleil S. Schutte, Jonathan Neumann, Bingyao Zhu, Diane K. O'Dowd, Grant R. MacGregor, Olga Safrina, Robert F. Hunt, Daniel R. Benavides, Lisha Zeng, An T. Pham, Yunyao Xie, Antara Das

المصدر: eNeuro, vol 8, iss 2
eNeuro

مصطلحات موضوعية: GEFS+, medicine.medical_specialty, Interneuron, Mutant, Neurodegenerative, Inhibitory postsynaptic potential, medicine.disease_cause, Inbred C57BL, Basic Behavioral and Social Science, Seizures, Febrile, Febrile, Epilepsy, Mice, parvalbumin interneurons, Interneurons, Seizures, Internal medicine, Febrile seizure, Behavioral and Social Science, medicine, Genetics, Animals, 2.1 Biological and endogenous factors, SCN1A, Aetiology, CRISPR/Cas9, Mutation, biology, General Neuroscience, Neurosciences, General Medicine, medicine.disease, Brain Disorders, Mice, Inbred C57BL, NAV1.1 Voltage-Gated Sodium Channel, medicine.anatomical_structure, Endocrinology, Neurological, biology.protein, Excitatory postsynaptic potential, epilepsy, Disorders of the Nervous System, Research Article: New Research, Parvalbumin

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::111daec53c4826bd8d7a13e15eef87fa
https://escholarship.org/uc/item/1b90h1jm

المؤلفون: Philip H. Schwartz, Diane K. O'Dowd, Kevin C. Ess, Martin A. Smith, Carmen M. Ramos, Nathan Ng, Yunyao Xie, Olga Safrina

المصدر: Neurobiology of Disease, Vol 134, Iss, Pp-(2020)

مصطلحات موضوعية: 0301 basic medicine, Genotype, Biology, Inhibitory postsynaptic potential, Seizures, Febrile, lcsh:RC321-571, 03 medical and health sciences, Epilepsy, 0302 clinical medicine, Control line, Genome editing, Dravet syndrome, Genetic epilepsy with febrile seizure plus, medicine, Humans, CRISPR, SCN1A, Induced pluripotent stem cell, lcsh:Neurosciences. Biological psychiatry. Neuropsychiatry, Gene, 030304 developmental biology, Neurons, Genetics, 0303 health sciences, Cas9, medicine.disease, 3. Good health, NAV1.1 Voltage-Gated Sodium Channel, Electrophysiology, Induced pluripotent stem cells, 030104 developmental biology, Phenotype, Neurology, Mutation, Isogenic, Mutation (genetic algorithm), 030217 neurology & neurosurgery

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db58f499fb56362cbe01fefdee0af00d
https://doi.org/10.1101/524835

المؤلفون: Anna Amcheslavsky, Olga Safrina, Michael D. Cahalan

المصدر: The Journal of General Physiology
Amcheslavsky, A; Safrina, O; & Cahalan, MD. (2014). State-dependent block of Orai3 TM1 and TM3 cysteine mutants: Insights into 2-APB activation. Journal of General Physiology, 143(5), 621-631. doi: 10.1085/jgp.201411171. UC Irvine: Retrieved from: http://www.escholarship.org/uc/item/7w65z761

مصطلحات موضوعية: Boron Compounds, Physiology, Stereochemistry, Mutant, Molecular Sequence Data, 03 medical and health sciences, 0302 clinical medicine, Protein structure, Humans, Amino Acid Sequence, Cysteine, Research Articles, 030304 developmental biology, 0303 health sciences, Voltage-dependent calcium channel, Chemistry, Endoplasmic reticulum, Mutagenesis, STIM1, Transmembrane protein, Protein Structure, Tertiary, HEK293 Cells, Mutation, Biophysics, sense organs, Calcium Channels, Ion Channel Gating, 030217 neurology & neurosurgery

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7033e480c281ea71537d30edded4837d
http://europepmc.org/articles/PMC4003185

المؤلفون: Michael W. Pennington, Alexander Flügel, Kevin Monaghan, Adriana Garcia, K. George Chandy, Srikant Rangaraju, Ian Parker, Victor Chi, Olga Safrina, Christine Beeton, Edwin S. Monuki, Sukumar Pal, Melanie P. Matheu, Michael D. Cahalan, Marc Uemura, Luis M. de la Maza, Dan Li

المصدر: Immunity. 29(4):602-614

مصطلحات موضوعية: Receptors, CCR7, Encephalomyelitis, Autoimmune, Experimental, Ovalbumin, T-Lymphocytes, Immunology, Motility, Antigen-Presenting Cells, Chlamydia trachomatis, Biology, Lymphocyte Activation, Article, Immune system, Orthomyxoviridae Infections, Cell Movement, medicine, Potassium Channel Blockers, Animals, Immunology and Allergy, Hypersensitivity, Delayed, MOLIMMUNO, Antigen-presenting cell, Calcium signaling, Kv1.3 Potassium Channel, Effector, Proteins, Potassium channel blocker, Chlamydia Infections, Orthomyxoviridae, Potassium channel, Cell biology, Rats, Infectious Diseases, CELLIMMUNO, Rats, Inbred Lew, Female, Collagen, Lymph Nodes, Immunologic Memory, medicine.drug, Homing (hematopoietic)

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d1eb5a73325e1dcfb8598969a3fadf93

المؤلفون: Aubin Penna, Angelo Demuro, Andriy V. Yeromin, Shenyuan L. Zhang, Olga Safrina, Ian Parker, Michael D. Cahalan

المصدر: Nature, Nature. 456(7218):116-120

الإتاحة: https://ideas.repec.org/a/nat/nature/v456y2008i7218d10.1038_nature07338.html

المؤلفون: Ying Yu, Ian Parker, Michael D. Cahalan, Sindy H. Wei, Kym R. Garrod, Olga Safrina

المصدر: The Journal of Immunology. 179:1586-1594

مصطلحات موضوعية: CD4-Positive T-Lymphocytes, Male, Cell signaling, Pathology, medicine.medical_specialty, Ovalbumin, T cell, Immunology, Antigen presentation, Epitopes, T-Lymphocyte, Mice, Transgenic, Inflammation, Cell Communication, Biology, Epitope, Mice, Basal (phylogenetics), Antigen, Cell Movement, medicine, Animals, Immunology and Allergy, Calcium Signaling, Lymph node, Cells, Cultured, Antigen Presentation, Mice, Inbred BALB C, Immunodominant Epitopes, Dendritic Cells, Molecular biology, Peptide Fragments, medicine.anatomical_structure, Cell Migration Inhibition, Lymph Nodes, Inflammation Mediators, medicine.symptom

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d0abe3dd7462159b6bae1a4af54c0560
https://doi.org/10.4049/jimmunol.179.3.1586

المؤلفون: Shenyuan L. Zhang, Weihua Jiang, Ying Yu, Olga Safrina, Michael D. Cahalan, Andriy V. Yeromin

المصدر: Nature. 443:226-229

مصطلحات موضوعية: ORAI1 Protein, Biology, Article, Cell Line, Animals, Drosophila Proteins, Humans, Channel blocker, Stromal Interaction Molecule 1, SOC channels, Multidisciplinary, Voltage-dependent calcium channel, ORAI1, Electric Conductivity, Membrane Proteins, STIM1, STIM2, Store-operated calcium entry, Cell biology, Protein Subunits, Drosophila melanogaster, Biochemistry, Mutation, ORAI2 Protein, Mutant Proteins, Calcium Channels, Ion Channel Gating

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::93ce0b2cc734ccee8ed2dfded7df14a6
https://doi.org/10.1038/nature05108

المؤلفون: Andriy V. Yeromin, Kenneth A. Stauderman, Xiang Zhang, Olga Safrina, Aubin Penna, Shenyuan L. Zhang, Ying Yu, Michael D. Cahalan, Jack Roos

المساهمون: Laboratory of Numerical Modeling for Atmospheric Sciences and Geophysical Fluid Dynamics (LASG), Institute of Atmospheric Physics [Beijing] (IAP), Chinese Academy of Sciences [Beijing] (CAS)-Chinese Academy of Sciences [Beijing] (CAS)

المصدر: Proceedings of the National Academy of Sciences of the United States of America
Proceedings of the National Academy of Sciences of the United States of America, National Academy of Sciences, 2006, 103 (24), pp.9357-9362. ⟨10.1073/pnas.0603161103⟩

مصطلحات موضوعية: Patch-Clamp Techniques, Thapsigargin, SERCA, Recombinant Fusion Proteins, Genome, Insect, [SDV.BC.BC]Life Sciences [q-bio]/Cellular Biology/Subcellular Processes [q-bio.SC], Biology, 03 medical and health sciences, chemistry.chemical_compound, Animals, Drosophila Proteins, Humans, Enzyme Inhibitors, ComputingMilieux_MISCELLANEOUS, RNA, Double-Stranded, 030304 developmental biology, SOC channels, 0303 health sciences, Multidisciplinary, ORAI1, 030302 biochemistry & molecular biology, STIM1, STIM2, Biological Sciences, Store-operated calcium entry, Cell biology, Drosophila melanogaster, chemistry, ORAI2 Protein, Calcium, RNA Interference, Calcium Channels, Signal Transduction

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::51adbebc2f58db80d09a38dc72a0e97c
https://doi.org/10.1073/pnas.0603161103

المؤلفون: Andriy V. Yeromin, Shenyuan L. Zhang, Weihua Jiang, Ying Yu, Olga Safrina, Michael D. Cahalan

المصدر: Nature, Nature. 443(7108):226-229

الإتاحة: https://ideas.repec.org/a/nat/nature/v443y2006i7108d10.1038_nature05108.html

المؤلفون: Ian Parker, Olga Safrina, Michael D. Cahalan, Mark J. Miller

المصدر: The Journal of Experimental Medicine

مصطلحات موضوعية: CD4-Positive T-Lymphocytes, Time Factors, T cell, Immunology, Antigen presentation, Mice, Transgenic, Biology, Lymphocyte Activation, Article, Immunological synapse, Mice, Cell Movement, medicine, T lymphocyte, Immunology and Allergy, Cytotoxic T cell, Animals, two-photon microscopy, Antigen-presenting cell, Mice, Inbred BALB C, Microscopy, CD40, Follicular dendritic cells, immunological synapse, Models, Immunological, CD28, Dendritic Cells, lymph node, Cell biology, antigen presentation, medicine.anatomical_structure, biology.protein, Lymph Nodes

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::827391557a10281f2905a8c6fc095293
http://europepmc.org/articles/PMC2213293