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المؤلفون: Bárbara B. Mendes, João Conniot, Aviram Avital, Dongbao Yao, Xingya Jiang, Xiang Zhou, Noga Sharf-Pauker, Yuling Xiao, Omer Adir, Haojun Liang, Jinjun Shi, Avi Schroeder, João Conde
المساهمون: NOVA Medical School|Faculdade de Ciências Médicas (NMS|FCM), Centre for Toxicogenomics and Human Health (ToxOmics)
المصدر: Nat Rev Methods Primers
مصطلحات موضوعية: DNA and RNA, Nanoparticles, Nanobiotechnology, General Medicine, Oligo delivery, Article, General Biochemistry, Genetics and Molecular Biology
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المؤلفون: Estelle De Roeck, Vincianne Jenart, Thuy Hang Nguyen, Anne-Emilie Decleves, Alexandra Belayew, Aline Derenne, Eugénie Ansseau, Alexandre Legrand, Alexandra Tassin, Frédérique Coppée
المصدر: Scientific Reports, Vol 10, Iss 1, Pp 1-15 (2020)
Scientific Reportsمصطلحات موضوعية: Expression systems, Molecular biology, Transgene, Science, Gene Expression, Mice, Transgenic, Biology, Oligo delivery, Article, Viral vector, Antisense oligonucleotide therapy, Mice, Gene expression analysis, DUX4, Animal disease models, Gene expression, medicine, Animals, Humans, Myocyte, Facioscapulohumeral muscular dystrophy, Gene delivery, Nucleic-acid therapeutics, Muscular dystrophy, Muscle, Skeletal, Biological models, Homeodomain Proteins, Multidisciplinary, Electroporation, Biological techniques, Model vertebrates, medicine.disease, Muscular Dystrophy, Facioscapulohumeral, Cell biology, Mice, Inbred C57BL, Disease Models, Animal, Musculoskeletal models, Medicine, Female, Experimental organisms, Biotechnology
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المصدر: Nature Communications, Vol 11, Iss 1, Pp 1-17 (2020)
Nature Communicationsمصطلحات موضوعية: 0301 basic medicine, Small interfering RNA, Cellular pathology, RNAi therapy, Endosome, Cell Survival, Science, Galectins, Green Fluorescent Proteins, General Physics and Astronomy, 02 engineering and technology, Endosomes, Cellular imaging, Oligo delivery, General Biochemistry, Genetics and Molecular Biology, Article, Small Molecule Libraries, 03 medical and health sciences, Cytosol, Imaging, Three-Dimensional, Downregulation and upregulation, Spheroids, Cellular, Gene Knockdown Techniques, Humans, RNA, Small Interfering, lcsh:Science, Gene knockdown, Multidisciplinary, Chemistry, Cell Membrane, RNA, Dextrans, General Chemistry, 021001 nanoscience & nanotechnology, Small molecule, Cell biology, 030104 developmental biology, Cholesterol, MCF-7 Cells, lcsh:Q, 0210 nano-technology, Lysosomes, HeLa Cells
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المؤلفون: Anna Moore, Ping Wang, Jack Owen Bishop, Qiong Liu, Hongwei Zhao, L. Karl Olson, Guoli Zhou
المصدر: Scientific Reports, Vol 10, Iss 1, Pp 1-12 (2020)
Scientific Reportsمصطلحات موضوعية: 0301 basic medicine, lcsh:Medicine, Oligo delivery, Article, Theranostic Nanomedicine, Diabetes Mellitus, Experimental, Cell delivery, 03 medical and health sciences, Mice, 0302 clinical medicine, Endocrinology, Downregulation and upregulation, In vivo, Mice, Inbred NOD, Insulin-Secreting Cells, medicine, Tensin, PTEN, Animals, lcsh:Science, NOD mice, Cell Proliferation, Mice, Inbred BALB C, Multidisciplinary, biology, Chemistry, Pancreatic islets, lcsh:R, Endocrine system and metabolic diseases, Disease Models, Animal, MicroRNAs, 030104 developmental biology, medicine.anatomical_structure, Diabetes Mellitus, Type 1, 030220 oncology & carcinogenesis, Cancer research, biology.protein, Female, lcsh:Q, Beta cell, Ex vivo, Biomarkers
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المؤلفون: Yuanyu Huang, Yongxiang Zhao, Yuhua Weng, Ling Peng, Bo Hu, Liping Zhong, Xing-Jie Liang
المساهمون: Guangxi Medical University, Centre Interdisciplinaire de Nanoscience de Marseille (CINaM), Aix Marseille Université (AMU)-Centre National de la Recherche Scientifique (CNRS), Beijing Institute of Technology (BIT), School of Economics and Management, Fuzhou University, This work was supported by the National Natural Science Foundation of China (31871003, 31901053), the Hunan Provincial Natural Science Foundation of China (2018JJ1019, 2019JJ50196), the Hu-Xiang Young Talent Program (2018RS3094), the Fundamental Research Funds for the Central Universities (3052018065) and the Beijing Institute of Technology Research Fund Program for Young Scholars. It was also supported, in part, by grants from the National Science and Technology Major Project of China (2019ZX09301-132), Program for Changjiang Scholars and Innovative Research Team in University of China (IRT_15R13)., National Center for Nanoscience and Technology of China
المصدر: Signal Transduction and Targeted Therapy
Signal Transduction and Targeted Therapy, 2020, 5 (1), ⟨10.1038/s41392-020-0207-x⟩
Signal Transduction and Targeted Therapy, Nature.com, 2020
Signal Transduction and Targeted Therapy, Nature.com, 2020, 5 (1), ⟨10.1038/s41392-020-0207-x⟩
Signal Transduction and Targeted Therapy, Vol 5, Iss 1, Pp 1-25 (2020)مصطلحات موضوعية: 0301 basic medicine, Cancer Research, Small interfering RNA, Extremely hard, Acetylgalactosamine, Pyrrolidines, Computer science, [SDV]Life Sciences [q-bio], lcsh:Medicine, Design elements and principles, Computational biology, [CHIM.THER]Chemical Sciences/Medicinal Chemistry, Review Article, Oligo delivery, 03 medical and health sciences, 0302 clinical medicine, Gene therapy, RNA interference, Genetics, Humans, [SDV.BBM]Life Sciences [q-bio]/Biochemistry, Molecular Biology, Nucleic-acid therapeutics, RNA, Small Interfering, lcsh:QH301-705.5, ComputingMilieux_MISCELLANEOUS, RNA, Double-Stranded, Mechanism (biology), lcsh:R, Genetic Diseases, Inborn, Genetic Therapy, 3. Good health, 030104 developmental biology, lcsh:Biology (General), Drug development, 030220 oncology & carcinogenesis, Drug delivery, RNA Interference
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c28a224460586d9661314abd4bdd7d59
https://hal.science/hal-02992725/document -
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المؤلفون: Ema Robinson, Yan Xia, Tatiana Ketova, Cosmin Mihai, Joseph P. Griffith, Siddharth Patel, Gaurav Sahay, Adam A. Esposito, Orn Almarsson, Kevin Welsher, John L. Joyal, Shangguo Hou, N. Ashwanikumar
المصدر: Nature Communications
Nature Communications, Vol 11, Iss 1, Pp 1-13 (2020)مصطلحات موضوعية: 0301 basic medicine, Endosome, Science, General Physics and Astronomy, Biological Transport, Active, 02 engineering and technology, Endosomes, Transfection, Oligo delivery, General Biochemistry, Genetics and Molecular Biology, Article, Cell Line, 03 medical and health sciences, chemistry.chemical_compound, Mice, X-Ray Diffraction, Animals, Humans, RNA, Messenger, Author Correction, lcsh:Science, Multidisciplinary, Chemistry, Cholesterol, HEK 293 cells, Cryoelectron Microscopy, RNA, General Chemistry, 021001 nanoscience & nanotechnology, Lipids, Sitosterols, Sterol, 3. Good health, Targeted gene repair, 030104 developmental biology, HEK293 Cells, RAW 264.7 Cells, DNA and RNA, Nucleic acid, Biophysics, Nanoparticles, lipids (amino acids, peptides, and proteins), lcsh:Q, 0210 nano-technology, Intracellular, HeLa Cells
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المؤلفون: Gilmar F. Salgado, Josué Carvalho, Jean-Louis Mergny, João A. Queiroz, Maria Paula Cabral Campello, Carla Cruz, António Paulo, Artur Paiva
المصدر: Scientific Reports
Scientific Reports, Vol 9, Iss 1, Pp 1-12 (2019)مصطلحات موضوعية: 0301 basic medicine, Transcription, Genetic, Cell Survival, media_common.quotation_subject, Aptamer, lcsh:Medicine, Antineoplastic Agents, G-quadruplex, Oligo delivery, Ligands, Article, Cell Line, HeLa, Proto-Oncogene Proteins c-myc, 03 medical and health sciences, 0302 clinical medicine, Cell Line, Tumor, Humans, Internalization, lcsh:Science, Promoter Regions, Genetic, media_common, Multidisciplinary, biology, Oligonucleotide, Chemistry, Ligand, lcsh:R, Gene Transfer Techniques, RNA-Binding Proteins, Aptamers, Nucleotide, Fibroblasts, biology.organism_classification, Phosphoproteins, G-Quadruplexes, Gene Expression Regulation, Neoplastic, 030104 developmental biology, Oligodeoxyribonucleotides, A549 Cells, Organ Specificity, Cancer cell, Drug delivery, Biophysics, lcsh:Q, Nucleolin, 030217 neurology & neurosurgery, HeLa Cells, Protein Binding
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8In vivo rendezvous of small nucleic acid drugs with charge-matched block catiomers to target cancers
المؤلفون: Kazuko Toh, Hiroaki Kinoh, Hiroyasu Takemoto, Mitsunobu R. Kano, Hiroshi Fukuhara, Sumiyo Watanabe, Keisuke Katsushima, Nobuhiro Nishiyama, Kotaro Hayashi, Yutaka Kondo, Hiroyuki Chaya, Satoshi Uchida, Satomi Ogura, Kanjiro Miyata, Takahiro Nomoto, Hyun Jin Kim, Horacio Cabral, Masaomi Nangaku, Kazunori Kataoka, Shigeto Fukushima, Shunya Uchida, Kensuke Osada, Xueying Liu, Yu Matsumoto, Hiroyoshi Y. Tanaka
المصدر: Nature Communications, Vol 10, Iss 1, Pp 1-13 (2019)
Nature Communicationsمصطلحات موضوعية: Male, 0301 basic medicine, Small interfering RNA, Oligonucleotides, General Physics and Astronomy, Cell Cycle Proteins, 02 engineering and technology, Polyethylene Glycols, Mice, Polylysine, RNA, Small Interfering, lcsh:Science, Regulation of gene expression, Drug Carriers, Multidisciplinary, Brain Neoplasms, Chemistry, Carbocyanines, 021001 nanoscience & nanotechnology, Gene Expression Regulation, Neoplastic, medicine.anatomical_structure, Injections, Intravenous, RNA, Long Noncoding, 0210 nano-technology, Pancreas, Science, Static Electricity, Antineoplastic Agents, Protein Serine-Threonine Kinases, Oligo delivery, Article, General Biochemistry, Genetics and Molecular Biology, 03 medical and health sciences, Targeted therapies, In vivo, Cell Line, Tumor, Proto-Oncogene Proteins, medicine, Animals, Humans, Fluorescent Dyes, Oligonucleotide, RNA, General Chemistry, Survival Analysis, Xenograft Model Antitumor Assays, Nanostructures, Pancreatic Neoplasms, 030104 developmental biology, Cell culture, Drug delivery, Cancer research, Nucleic acid, lcsh:Q
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