المؤلفون: Sachs N; Oncode Institute, Hubrecht Institute-KNAW and UMC Utrecht, Utrecht, The Netherlands., Papaspyropoulos A; Oncode Institute, Hubrecht Institute-KNAW and UMC Utrecht, Utrecht, The Netherlands., Zomer-van Ommen DD; Wilhelmina Children's Hospital and UMC Utrecht, Utrecht, The Netherlands., Heo I; Oncode Institute, Hubrecht Institute-KNAW and UMC Utrecht, Utrecht, The Netherlands., Böttinger L; Oncode Institute, Hubrecht Institute-KNAW and UMC Utrecht, Utrecht, The Netherlands., Klay D; St. Antonius Hospital Nieuwegein, Nieuwegein, The Netherlands., Weeber F; The Netherlands Cancer Institute, Amsterdam, The Netherlands., Huelsz-Prince G; FOM Institute AMOLF, Amsterdam, The Netherlands., Iakobachvili N; Maastricht University, Maastricht, The Netherlands., Amatngalim GD; Wilhelmina Children's Hospital and UMC Utrecht, Utrecht, The Netherlands., de Ligt J; UMC Utrecht, Utrecht, The Netherlands., van Hoeck A; UMC Utrecht, Utrecht, The Netherlands., Proost N; Mouse Clinic for Cancer and Aging (MCCA) Preclinical Intervention Unit, The Netherlands Cancer Institute, Amsterdam, The Netherlands., Viveen MC; UMC Utrecht, Utrecht, The Netherlands., Lyubimova A; Oncode Institute, Hubrecht Institute-KNAW and UMC Utrecht, Utrecht, The Netherlands., Teeven L; Oncode Institute, Hubrecht Institute-KNAW and UMC Utrecht, Utrecht, The Netherlands., Derakhshan S; Wilhelmina Children's Hospital and UMC Utrecht, Utrecht, The Netherlands., Korving J; Oncode Institute, Hubrecht Institute-KNAW and UMC Utrecht, Utrecht, The Netherlands., Begthel H; Oncode Institute, Hubrecht Institute-KNAW and UMC Utrecht, Utrecht, The Netherlands., Dekkers JF; Oncode Institute, Hubrecht Institute-KNAW and UMC Utrecht, Utrecht, The Netherlands., Kumawat K; Wilhelmina Children's Hospital and UMC Utrecht, Utrecht, The Netherlands., Ramos E; Hubrecht Organoid Technology, Utrecht, The Netherlands., van Oosterhout MF; St. Antonius Hospital Nieuwegein, Nieuwegein, The Netherlands., Offerhaus GJ; UMC Utrecht, Utrecht, The Netherlands., Wiener DJ; Oncode Institute, Hubrecht Institute-KNAW and UMC Utrecht, Utrecht, The Netherlands., Olimpio EP; FOM Institute AMOLF, Amsterdam, The Netherlands., Dijkstra KK; The Netherlands Cancer Institute, Amsterdam, The Netherlands., Smit EF; The Netherlands Cancer Institute, Amsterdam, The Netherlands., van der Linden M; Wilhelmina Children's Hospital and UMC Utrecht, Utrecht, The Netherlands., Jaksani S; Hubrecht Organoid Technology, Utrecht, The Netherlands., van de Ven M; Mouse Clinic for Cancer and Aging (MCCA) Preclinical Intervention Unit, The Netherlands Cancer Institute, Amsterdam, The Netherlands., Jonkers J; Mouse Clinic for Cancer and Aging (MCCA) Preclinical Intervention Unit, The Netherlands Cancer Institute, Amsterdam, The Netherlands., Rios AC; Princess Máxima Center for Pediatric Oncology, Utrecht, The Netherlands., Voest EE; The Netherlands Cancer Institute, Amsterdam, The Netherlands., van Moorsel CH; St. Antonius Hospital Nieuwegein, Nieuwegein, The Netherlands., van der Ent CK; Wilhelmina Children's Hospital and UMC Utrecht, Utrecht, The Netherlands., Cuppen E; UMC Utrecht, Utrecht, The Netherlands., van Oudenaarden A; Oncode Institute, Hubrecht Institute-KNAW and UMC Utrecht, Utrecht, The Netherlands., Coenjaerts FE; UMC Utrecht, Utrecht, The Netherlands., Meyaard L; Wilhelmina Children's Hospital and UMC Utrecht, Utrecht, The Netherlands., Bont LJ; Wilhelmina Children's Hospital and UMC Utrecht, Utrecht, The Netherlands., Peters PJ; Maastricht University, Maastricht, The Netherlands., Tans SJ; FOM Institute AMOLF, Amsterdam, The Netherlands., van Zon JS; FOM Institute AMOLF, Amsterdam, The Netherlands., Boj SF; Hubrecht Organoid Technology, Utrecht, The Netherlands., Vries RG; Hubrecht Organoid Technology, Utrecht, The Netherlands., Beekman JM; Wilhelmina Children's Hospital and UMC Utrecht, Utrecht, The Netherlands., Clevers H; Oncode Institute, Hubrecht Institute-KNAW and UMC Utrecht, Utrecht, The Netherlands h.clevers@hubrecht.eu.; Princess Máxima Center for Pediatric Oncology, Utrecht, The Netherlands.

المصدر: The EMBO journal [EMBO J] 2019 Feb 15; Vol. 38 (4). Date of Electronic Publication: 2019 Jan 14.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 8208664 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1460-2075 (Electronic) Linking ISSN: 02614189 NLM ISO Abbreviation: EMBO J Subsets: MEDLINE

مواضيع طبية MeSH: Carcinoma, Non-Small-Cell Lung/*pathology , Cystic Fibrosis/*pathology , Epithelial Cells/*pathology , Organ Culture Techniques/*methods , Organoids/*pathology , Respiratory Syncytial Virus Infections/*pathology , Respiratory System/*pathology, Animals ; Carcinoma, Non-Small-Cell Lung/drug therapy ; Carcinoma, Non-Small-Cell Lung/metabolism ; Cells, Cultured ; Cystic Fibrosis/metabolism ; Cystic Fibrosis Transmembrane Conductance Regulator/metabolism ; Disease Models, Animal ; Drug Screening Assays, Antitumor ; Epithelial Cells/metabolism ; Female ; Humans ; Lung Neoplasms/drug therapy ; Lung Neoplasms/metabolism ; Lung Neoplasms/pathology ; Male ; Mice ; Mice, Inbred NOD ; Mice, SCID ; Organoids/metabolism ; Respiratory Syncytial Virus Infections/virology ; Respiratory Syncytial Viruses/isolation & purification ; Respiratory System/metabolism ; Xenograft Model Antitumor Assays

المؤلفون: Olimpio EP; Kavli Institute of Nanoscience, Delft University of Technology, Delft, the Netherlands; Department of Bionanoscience, Delft University of Technology, Delft 2629HZ, the Netherlands., Dang Y; Kavli Institute of Nanoscience, Delft University of Technology, Delft, the Netherlands; Department of Bionanoscience, Delft University of Technology, Delft 2629HZ, the Netherlands., Youk H; Kavli Institute of Nanoscience, Delft University of Technology, Delft, the Netherlands; Department of Bionanoscience, Delft University of Technology, Delft 2629HZ, the Netherlands. Electronic address: h.youk@tudelft.nl.

المصدر: IScience [iScience] 2018 Apr 27; Vol. 2, pp. 27-40. Date of Electronic Publication: 2018 Apr 06.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Cell Press Country of Publication: United States NLM ID: 101724038 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2589-0042 (Electronic) Linking ISSN: 25890042 NLM ISO Abbreviation: iScience Subsets: PubMed not MEDLINE