المؤلفون: Pedron CN; Centro de Ciências Naturais e Humanas, Universidade Federal do ABC, Santo André, SP, 09210580, Brazil.; Departamento de Bioquímica, Universidade Federal de São Paulo, São Paulo, SP, 04044020, Brazil., Torres MT; Machine Biology Group, Departments of Psychiatry and Microbiology, Institute for Biomedical Informatics, Institute for Translational Medicine and Therapeutics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.; Departments of Bioengineering and Chemical and Biomolecular Engineering, School of Engineering and Applied Science, University of Pennsylvania, Philadelphia, PA, USA.; Penn Institute for Computational Science, University of Pennsylvania, Philadelphia, PA, USA., Oliveira CS; Departamento de Bioquímica, Universidade Federal de São Paulo, São Paulo, SP, 04044020, Brazil., Silva AF; Departamento de Biofísica, Universidade Federal de São Paulo, São Paulo, SP, 04044020, Brazil., Andrade GP; Centro de Ciências Naturais e Humanas, Universidade Federal do ABC, Santo André, SP, 09210580, Brazil.; Departamento de Biofísica, Universidade Federal de São Paulo, São Paulo, SP, 04044020, Brazil., Wang Y; Departments of Bioengineering and Chemical and Biomolecular Engineering, School of Engineering and Applied Science, University of Pennsylvania, Philadelphia, PA, USA.; Penn Institute for Computational Science, University of Pennsylvania, Philadelphia, PA, USA., Pinhal MAS; Departamento de Bioquímica, Universidade Federal de São Paulo, São Paulo, SP, 04044020, Brazil., Cerchiaro G; Centro de Ciências Naturais e Humanas, Universidade Federal do ABC, Santo André, SP, 09210580, Brazil., da Silva Junior PI; Laboratório de Toxinologia Aplicada (LETA) - Instituto Butantan, São Paulo, SP, 05503900, Brazil., da Silva FD; Centro de Ciências Naturais e Humanas, Universidade Federal do ABC, Santo André, SP, 09210580, Brazil., Radhakrishnan R; Departments of Bioengineering and Chemical and Biomolecular Engineering, School of Engineering and Applied Science, University of Pennsylvania, Philadelphia, PA, USA.; Penn Institute for Computational Science, University of Pennsylvania, Philadelphia, PA, USA., de la Fuente-Nunez C; Machine Biology Group, Departments of Psychiatry and Microbiology, Institute for Biomedical Informatics, Institute for Translational Medicine and Therapeutics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA. cfuente@upenn.edu.; Departments of Bioengineering and Chemical and Biomolecular Engineering, School of Engineering and Applied Science, University of Pennsylvania, Philadelphia, PA, USA. cfuente@upenn.edu.; Penn Institute for Computational Science, University of Pennsylvania, Philadelphia, PA, USA. cfuente@upenn.edu., Oliveira Junior VX; Centro de Ciências Naturais e Humanas, Universidade Federal do ABC, Santo André, SP, 09210580, Brazil. vani.junior@ufabc.edu.br.; Departamento de Bioquímica, Universidade Federal de São Paulo, São Paulo, SP, 04044020, Brazil. vani.junior@ufabc.edu.br.

المصدر: Communications biology [Commun Biol] 2023 Oct 19; Vol. 6 (1), pp. 1067. Date of Electronic Publication: 2023 Oct 19.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Nature Publishing Group UK Country of Publication: England NLM ID: 101719179 Publication Model: Electronic Cited Medium: Internet ISSN: 2399-3642 (Electronic) Linking ISSN: 23993642 NLM ISO Abbreviation: Commun Biol Subsets: MEDLINE

مواضيع طبية MeSH: Antimicrobial Cationic Peptides*/genetics , Antimicrobial Cationic Peptides*/pharmacology , Antimicrobial Cationic Peptides*/chemistry , Anti-Infective Agents*/pharmacology, Humans ; Amino Acid Sequence

المؤلفون: Monteiro ML; Department of Clinical and Toxicological Analysis, Faculdade de Farmácia, Universidade Federal do Ceará, Fortaleza, 60430372, CE, Brazil., Lima DB; Department of Clinical and Toxicological Analysis, Faculdade de Farmácia, Universidade Federal do Ceará, Fortaleza, 60430372, CE, Brazil., Freire KA; Centro de Ciências Naturais e Humanas, Universidade Federal do ABC, Santo André, 09210580, SP, Brazil., Nicolaski Pedron C; Centro de Ciências Naturais e Humanas, Universidade Federal do ABC, Santo André, 09210580, SP, Brazil., Magalhães EP; Department of Clinical and Toxicological Analysis, Faculdade de Farmácia, Universidade Federal do Ceará, Fortaleza, 60430372, CE, Brazil., Silva BP; Department of Clinical and Toxicological Analysis, Faculdade de Farmácia, Universidade Federal do Ceará, Fortaleza, 60430372, CE, Brazil., García-Jareño AB; Targeted Therapies on Cancer and Inflammation Lab and Peptide Synthesis Platform, Centro de Investigación Príncipe Felipe, Valencia, 46012, Spain., De Oliveira CS; Department of Biophysics, Universidade Federal de São Paulo, São Paulo, SP, 04044020, Brazil., Nunes JVS; Department of Clinical and Toxicological Analysis, Faculdade de Farmácia, Universidade Federal do Ceará, Fortaleza, 60430372, CE, Brazil., Marinho MM; Department of Clinical and Toxicological Analysis, Faculdade de Farmácia, Universidade Federal do Ceará, Fortaleza, 60430372, CE, Brazil., Menezes RRPPB; Department of Clinical and Toxicological Analysis, Faculdade de Farmácia, Universidade Federal do Ceará, Fortaleza, 60430372, CE, Brazil., Orzaéz M; Targeted Therapies on Cancer and Inflammation Lab and Peptide Synthesis Platform, Centro de Investigación Príncipe Felipe, Valencia, 46012, Spain., Oliveira Junior VX; Centro de Ciências Naturais e Humanas, Universidade Federal do ABC, Santo André, 09210580, SP, Brazil; Department of Biophysics, Universidade Federal de São Paulo, São Paulo, SP, 04044020, Brazil., Martins AMC; Department of Clinical and Toxicological Analysis, Faculdade de Farmácia, Universidade Federal do Ceará, Fortaleza, 60430372, CE, Brazil. Electronic address: martinsalice@gmail.com.

المصدر: European journal of medicinal chemistry [Eur J Med Chem] 2022 Nov 05; Vol. 241, pp. 114624. Date of Electronic Publication: 2022 Jul 31.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Editions Scientifiques Elsevier Country of Publication: France NLM ID: 0420510 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1768-3254 (Electronic) Linking ISSN: 02235234 NLM ISO Abbreviation: Eur J Med Chem Subsets: MEDLINE

مواضيع طبية MeSH: Chagas Disease*/drug therapy , Trypanocidal Agents*/therapeutic use , Trypanosoma cruzi*, Humans ; Peptides/pharmacology ; Peptides/therapeutic use ; Venoms

المؤلفون: Pedron CN; Centro de Ciências Naturais e Humanas, Universidade Federal do ABC, Santo André, SP, 09210580, Brazil.; Departamento de Biofísica, Universidade Federal de São Paulo, São Paulo, SP, 04044020, Brazil., Silva AF; Centro de Ciências Naturais e Humanas, Universidade Federal do ABC, Santo André, SP, 09210580, Brazil.; Departamento de Biofísica, Universidade Federal de São Paulo, São Paulo, SP, 04044020, Brazil., Torres MT; Machine Biology Group, Departments of Psychiatry and Microbiology, Institute for Biomedical Informatics, Institute for Translational Medicine and Therapeutics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, 19102, USA.; Departments of Bioengineering and Chemical and Biomolecular Engineering, School of Engineering and Applied Science, University of Pennsylvania, Philadelphia, PA, 19102, USA.; Penn Institute for Computational Science, University of Pennsylvania, Philadelphia, PA, 19102, USA., Oliveira CS; Departamento de Biofísica, Universidade Federal de São Paulo, São Paulo, SP, 04044020, Brazil., Andrade GP; Centro de Ciências Naturais e Humanas, Universidade Federal do ABC, Santo André, SP, 09210580, Brazil., Cerchiaro G; Centro de Ciências Naturais e Humanas, Universidade Federal do ABC, Santo André, SP, 09210580, Brazil., Pinhal MAS; Departamento de Biofísica, Universidade Federal de São Paulo, São Paulo, SP, 04044020, Brazil., de la Fuente-Nunez C; Machine Biology Group, Departments of Psychiatry and Microbiology, Institute for Biomedical Informatics, Institute for Translational Medicine and Therapeutics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, 19102, USA.; Departments of Bioengineering and Chemical and Biomolecular Engineering, School of Engineering and Applied Science, University of Pennsylvania, Philadelphia, PA, 19102, USA.; Penn Institute for Computational Science, University of Pennsylvania, Philadelphia, PA, 19102, USA., Oliveira Junior VX; Centro de Ciências Naturais e Humanas, Universidade Federal do ABC, Santo André, SP, 09210580, Brazil.; Departamento de Biofísica, Universidade Federal de São Paulo, São Paulo, SP, 04044020, Brazil.

المصدر: Journal of peptide science : an official publication of the European Peptide Society [J Pept Sci] 2021 Apr; Vol. 27 (4), pp. e3296. Date of Electronic Publication: 2021 Jan 13.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: John Wiley & Sons Country of Publication: England NLM ID: 9506309 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1099-1387 (Electronic) Linking ISSN: 10752617 NLM ISO Abbreviation: J Pept Sci Subsets: MEDLINE

مواضيع طبية MeSH: Antimalarials/*pharmacology , Antimicrobial Cationic Peptides/*pharmacology , Antineoplastic Agents/*pharmacology , Malaria/*drug therapy , Plasmodium gallinaceum/*drug effects , Scorpion Venoms/*pharmacology, Animals ; Antimalarials/chemistry ; Antimalarials/isolation & purification ; Antimicrobial Cationic Peptides/chemistry ; Antimicrobial Cationic Peptides/isolation & purification ; Antineoplastic Agents/chemistry ; Antineoplastic Agents/isolation & purification ; Cell Line ; Cell Proliferation/drug effects ; Cell Survival/drug effects ; Drug Screening Assays, Antitumor ; Humans ; Parasitic Sensitivity Tests ; Scorpion Venoms/chemistry ; Scorpion Venoms/isolation & purification ; Scorpions

المؤلفون: Pedron CN; Universidade Federal do ABC, Centro de Ciências Naturais e Humanas, 5001 Avenida dos Estados, Santo André, 09210580 SP, Brazil., Araújo I; Universidade Federal do ABC, Centro de Ciências Naturais e Humanas, 5001 Avenida dos Estados, Santo André, 09210580 SP, Brazil., da Silva Junior PI; Instituto Butantan, Laboratório Especial de Toxinologia Aplicada, 1500 Avenida Vital Brasil, 05503900 São Paulo, SP, Brazil., Dias da Silva F; Universidade Federal do ABC, Centro de Ciências Naturais e Humanas, 5001 Avenida dos Estados, Santo André, 09210580 SP, Brazil., Torres MT; Departments of Psychiatry and Microbiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia 19104, PA, United States; Department of Bioengineering, University of Pennsylvania, Philadelphia 19104, PA, United States. Electronic address: marcelot@pennmedicine.upenn.edu., Oliveira Junior VX; Universidade Federal do ABC, Centro de Ciências Naturais e Humanas, 5001 Avenida dos Estados, Santo André, 09210580 SP, Brazil; Universidade Federal de São Paulo, 100 Rua 3 de Maio, 04044020 São Paulo, SP, Brazil. Electronic address: vani.junior@ufabc.edu.br.

المصدر: Bioorganic chemistry [Bioorg Chem] 2019 Sep; Vol. 90, pp. 103038. Date of Electronic Publication: 2019 Jun 08.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Elsevier Country of Publication: United States NLM ID: 1303703 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1090-2120 (Electronic) Linking ISSN: 00452068 NLM ISO Abbreviation: Bioorg Chem Subsets: MEDLINE

مواضيع طبية MeSH: Anti-Bacterial Agents/*pharmacology , Antifungal Agents/*pharmacology , Antimicrobial Cationic Peptides/*pharmacology , Scorpion Venoms/*pharmacology, Amino Acid Substitution ; Anti-Bacterial Agents/chemistry ; Anti-Bacterial Agents/toxicity ; Antifungal Agents/chemistry ; Antifungal Agents/toxicity ; Antimicrobial Cationic Peptides/chemistry ; Antimicrobial Cationic Peptides/toxicity ; Candida albicans/drug effects ; Candida tropicalis/drug effects ; Drug Design ; Erythrocytes/drug effects ; Gram-Negative Bacteria/drug effects ; Gram-Positive Bacteria/drug effects ; Hemolysis/drug effects ; Humans ; Microbial Sensitivity Tests ; Molecular Structure ; Scorpion Venoms/chemistry ; Scorpion Venoms/toxicity ; Structure-Activity Relationship

المؤلفون: Torres MDT; 1Synthetic Biology Group, MIT Synthetic Biology Center; The Center for Microbiome Informatics and Therapeutics; Research Laboratory of Electronics, Department of Biological Engineering, and Department of Electrical Engineering and Computer Science, Massachusetts Institute of Technology, Cambridge, MA 02139 USA.; 2Broad Institute of MIT and Harvard, Cambridge, MA 02142 USA.; 3Centro de Ciências Naturais e Humanas, Universidade Federal do ABC, Santo André, SP 09210580 Brazil., Pedron CN; 3Centro de Ciências Naturais e Humanas, Universidade Federal do ABC, Santo André, SP 09210580 Brazil., Higashikuni Y; 1Synthetic Biology Group, MIT Synthetic Biology Center; The Center for Microbiome Informatics and Therapeutics; Research Laboratory of Electronics, Department of Biological Engineering, and Department of Electrical Engineering and Computer Science, Massachusetts Institute of Technology, Cambridge, MA 02139 USA.; 2Broad Institute of MIT and Harvard, Cambridge, MA 02142 USA., Kramer RM; 4Division of Comparative Medicine, Massachusetts Institute of Technology, Cambridge, MA 02139 USA., Cardoso MH; 5Programa de Pós-Gradução em Patologia Molecular, Faculdade de Medicina, Universidade de Brasília, Brasília, DF 70297400 Brazil.; 6Centro de Análises Proteômicas e Bioquímicas, Universidade Católica de Brasília, Brasília, DF 71966700 Brazil.; 7S-inova Biotech, Programa de Pós-Graduação em Biotecnologia, Universidade Católica Dom Bosco, Campo Grande, MS 79117010 Brazil., Oshiro KGN; 7S-inova Biotech, Programa de Pós-Graduação em Biotecnologia, Universidade Católica Dom Bosco, Campo Grande, MS 79117010 Brazil., Franco OL; 5Programa de Pós-Gradução em Patologia Molecular, Faculdade de Medicina, Universidade de Brasília, Brasília, DF 70297400 Brazil.; 6Centro de Análises Proteômicas e Bioquímicas, Universidade Católica de Brasília, Brasília, DF 71966700 Brazil.; 7S-inova Biotech, Programa de Pós-Graduação em Biotecnologia, Universidade Católica Dom Bosco, Campo Grande, MS 79117010 Brazil., Silva Junior PI; 8Laboratório Especial de Toxinologia Aplicada, Instituto Butantan, São Paulo, SP 05503900 Brazil., Silva FD; 3Centro de Ciências Naturais e Humanas, Universidade Federal do ABC, Santo André, SP 09210580 Brazil., Oliveira Junior VX; 3Centro de Ciências Naturais e Humanas, Universidade Federal do ABC, Santo André, SP 09210580 Brazil., Lu TK; 1Synthetic Biology Group, MIT Synthetic Biology Center; The Center for Microbiome Informatics and Therapeutics; Research Laboratory of Electronics, Department of Biological Engineering, and Department of Electrical Engineering and Computer Science, Massachusetts Institute of Technology, Cambridge, MA 02139 USA.; 2Broad Institute of MIT and Harvard, Cambridge, MA 02142 USA., de la Fuente-Nunez C; 1Synthetic Biology Group, MIT Synthetic Biology Center; The Center for Microbiome Informatics and Therapeutics; Research Laboratory of Electronics, Department of Biological Engineering, and Department of Electrical Engineering and Computer Science, Massachusetts Institute of Technology, Cambridge, MA 02139 USA.; 2Broad Institute of MIT and Harvard, Cambridge, MA 02142 USA.

المصدر: Communications biology [Commun Biol] 2018 Dec 07; Vol. 1, pp. 221. Date of Electronic Publication: 2018 Dec 07 (Print Publication: 2018).

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Nature Publishing Group UK Country of Publication: England NLM ID: 101719179 Publication Model: eCollection Cited Medium: Internet ISSN: 2399-3642 (Electronic) Linking ISSN: 23993642 NLM ISO Abbreviation: Commun Biol Subsets: PubMed not MEDLINE

المؤلفون: Torres MD; Universidade Federal do ABC, Centro de Ciências Naturais e Humanas, Santo André, SP, Brazil., Silva AF; Universidade Federal do ABC, Centro de Ciências Naturais e Humanas, Santo André, SP, Brazil., Alves FL; Universidade Federal de São Paulo, Departamento de Biofísica, São Paulo, SP, Brazil., Capurro ML; Universidade de São Paulo, Instituto de Ciências Biomédicas II, São Paulo, SP, Brazil., Miranda A; Universidade Federal de São Paulo, Departamento de Biofísica, São Paulo, SP, Brazil., Cordeiro RM; Universidade Federal do ABC, Centro de Ciências Naturais e Humanas, Santo André, SP, Brazil., Oliveira Junior VX; Universidade Federal do ABC, Centro de Ciências Naturais e Humanas, Santo André, SP, Brazil.

المصدر: Journal of peptide science : an official publication of the European Peptide Society [J Pept Sci] 2016 Mar; Vol. 22 (3), pp. 132-42.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: John Wiley & Sons Country of Publication: England NLM ID: 9506309 Publication Model: Print Cited Medium: Internet ISSN: 1099-1387 (Electronic) Linking ISSN: 10752617 NLM ISO Abbreviation: J Pept Sci Subsets: MEDLINE

مواضيع طبية MeSH: Angiotensin II/*pharmacology , Antimalarials/*pharmacology , Cell Membrane/*drug effects , Peptides/*pharmacology , Plasmodium gallinaceum/*drug effects , Sporozoites/*drug effects, Aedes/parasitology ; Amino Acid Sequence ; Angiotensin II/analogs & derivatives ; Angiotensin II/chemical synthesis ; Animals ; Antimalarials/chemical synthesis ; Antimalarials/chemistry ; Chickens ; Malaria, Avian/drug therapy ; Malaria, Avian/parasitology ; Mice ; Micelles ; Models, Molecular ; Molecular Dynamics Simulation ; Molecular Sequence Data ; Muscle Contraction/drug effects ; Peptides/chemical synthesis ; Peptides/chemistry ; Plasmodium gallinaceum/growth & development ; Plasmodium gallinaceum/metabolism ; Salivary Glands/parasitology ; Solid-Phase Synthesis Techniques ; Stereoisomerism ; Structure-Activity Relationship

المؤلفون: Maciel C; Department of Parasitology, Institute of Biomedical Sciences, University of São Paulo, São Paulo, Brazil., de Oliveira Junior VX, Fázio MA, Nacif-Pimenta R, Miranda A, Pimenta PF, Capurro ML

المصدر: PloS one [PLoS One] 2008 Sep 29; Vol. 3 (9), pp. e3296. Date of Electronic Publication: 2008 Sep 29.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: Electronic Cited Medium: Internet ISSN: 1932-6203 (Electronic) Linking ISSN: 19326203 NLM ISO Abbreviation: PLoS One Subsets: MEDLINE

مواضيع طبية MeSH: Angiotensin II/*pharmacology , Antiparasitic Agents/*pharmacology , Malaria/*drug therapy, Aedes/genetics ; Angiotensin I/chemistry ; Angiotensin II/chemistry ; Animals ; Cell Membrane/drug effects ; Chickens ; Cytoplasm/metabolism ; Hemolysis ; Humans ; Models, Statistical ; Peptides/chemistry ; Peptides/therapeutic use ; Plasmodium gallinaceum/metabolism ; Sporozoites/metabolism