المؤلفون: Teresa, Brevini, Mailis, Maes, Gwilym J, Webb, Binu V, John, Claudia D, Fuchs, Gustav, Buescher, Lu, Wang, Chelsea, Griffiths, Marnie L, Brown, William E, Scott, Pehuén, Pereyra-Gerber, William T H, Gelson, Stephanie, Brown, Scott, Dillon, Daniele, Muraro, Jo, Sharp, Megan, Neary, Helen, Box, Lee, Tatham, James, Stewart, Paul, Curley, Henry, Pertinez, Sally, Forrest, Petra, Mlcochova, Sagar S, Varankar, Mahnaz, Darvish-Damavandi, Victoria L, Mulcahy, Rhoda E, Kuc, Thomas L, Williams, James A, Heslop, Davide, Rossetti, Olivia C, Tysoe, Vasileios, Galanakis, Marta, Vila-Gonzalez, Thomas W M, Crozier, Johannes, Bargehr, Sanjay, Sinha, Sara S, Upponi, Corrina, Fear, Lisa, Swift, Kourosh, Saeb-Parsy, Susan E, Davies, Axel, Wester, Hannes, Hagström, Espen, Melum, Darran, Clements, Peter, Humphreys, Jo, Herriott, Edyta, Kijak, Helen, Cox, Chloe, Bramwell, Anthony, Valentijn, Christopher J R, Illingworth, Bassam, Dahman, Dustin R, Bastaich, Raphaella D, Ferreira, Thomas, Marjot, Eleanor, Barnes, Andrew M, Moon, Alfred S, Barritt, Ravindra K, Gupta, Stephen, Baker, Anthony P, Davenport, Gareth, Corbett, Vassilis G, Gorgoulis, Simon J A, Buczacki, Joo-Hyeon, Lee, Nicholas J, Matheson, Michael, Trauner, Andrew J, Fisher, Paul, Gibbs, Andrew J, Butler, Christopher J E, Watson, George F, Mells, Gordon, Dougan, Andrew, Owen, Ansgar W, Lohse, Ludovic, Vallier, Fotios, Sampaziotis

المساهمون: consortium, UK-PBC research

المصدر: Nature. 615:134-142

مصطلحات موضوعية: Multidisciplinary

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a3d1f48c490c312e0492b836b250c36f
https://doi.org/10.1038/s41586-022-05594-0

المؤلفون: Brandon T. Wesley, Alexander D. B. Ross, Daniele Muraro, Zhichao Miao, Sarah Saxton, Rute A. Tomaz, Carola M. Morell, Katherine Ridley, Ekaterini D. Zacharis, Sandra Petrus-Reurer, Judith Kraiczy, Krishnaa T. Mahbubani, Stephanie Brown, Jose Garcia-Bernardo, Clara Alsinet, Daniel Gaffney, Dave Horsfall, Olivia C. Tysoe, Rachel A. Botting, Emily Stephenson, Dorin-Mirel Popescu, Sonya MacParland, Gary Bader, Ian D. McGilvray, Daniel Ortmann, Fotios Sampaziotis, Kourosh Saeb-Parsy, Muzlifah Haniffa, Kelly R. Stevens, Matthias Zilbauer, Sarah A. Teichmann, Ludovic Vallier

المصدر: Nature Cell Biology. 24:1487-1498

مصطلحات موضوعية: Organoids, Liver, Hepatocytes, Humans, Cell Differentiation, Cell Biology, Transcription Factors

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c2f2e9ea02987281a5813a196e29654f
https://doi.org/10.1038/s41556-022-00989-7

المؤلفون: Brandon T. Wesley, Alexander D. B. Ross, Daniele Muraro, Zhichao Miao, Sarah Saxton, Rute A. Tomaz, Carola M. Morell, Katherine Ridley, Ekaterini D. Zacharis, Sandra Petrus-Reurer, Judith Kraiczy, Krishnaa T. Mahbubani, Stephanie Brown, Jose Garcia-Bernardo, Clara Alsinet, Daniel Gaffney, Olivia C. Tysoe, Rachel A. Botting, Emily Stephenson, Dorin-Mirel Popescu, Sonya MacParland, Gary Bader, Ian D. McGilvray, Daniel Ortmann, Fotios Sampaziotis, Kourosh Saeb-Parsy, Muzlifah Haniffa, Kelly R. Stevens, Matthias Zilbauer, Sarah A. Teichmann, Ludovic Vallier

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::70e81572564a3d9e4632e69e581518ed
https://doi.org/10.1101/2022.03.08.482299

المؤلفون: Teresa Brevini, Olivia C. Tysoe, Fotios Sampaziotis

المصدر: Journal of Hepatology. 73:918-932

مصطلحات موضوعية: 0301 basic medicine, Cholestasis, Tissue Engineering, Hepatology, business.industry, Epithelial Cells, Disease pathogenesis, Dynamic modelling, 03 medical and health sciences, 030104 developmental biology, 0302 clinical medicine, Tissue engineering, Biliary tract, Animals, Humans, Medicine, 030211 gastroenterology & hepatology, Cholestatic liver disease, Biliary Tract, business, Neuroscience

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ccb51d2e7952e0a1787308dc09b5da56
https://doi.org/10.1016/j.jhep.2020.05.049

المؤلفون: Olivia C. Tysoe, A Butler, Daniele Muraro, T. Brevini, Alfred Barritt, Sara Upponi, Gordon Dougan, Eleanor Barnes, R. E. Kuc, V. L. Mulcahy, Sally Forrest, Andrew Davenport, S. J. A. Buczacki, T. L. Williams, Ludovic Vallier, Mailis Maes, Paul Gibbs, S. Varankar, R. K. Gupta, Ansgar W. Lohse, George F. Mells, S. Baker, Christopher J.E. Watson, Andrew M. Moon, Kourosh Saeb-Parsy, P. Mlcochova, Sanjay Sinha, L. Swift, T. W. M. Crozier, M. Darvish-Damavandi, Susan E. Davies, Johannes Bargehr, M. Vila-Gonzalez, Gwilym J. Webb, William Gelson, F. Sampaziotis, Thomas Marjot, V. Galanakis, J. H. Lee, S. Dillon, Gareth Corbett

المصدر: Oral.

مصطلحات موضوعية: medicine.diagnostic_test, business.industry, Pharmacology, Cholangiocyte, Ursodeoxycholic acid, Transplantation, Clinical trial, Bronchoalveolar lavage, Downregulation and upregulation, In vivo, medicine, Organoid, business, hormones, hormone substitutes, and hormone antagonists, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::ac294d004b698ff6e4a55be518fa5174
https://doi.org/10.1136/gutjnl-2021-basl.7

المؤلفون: Olivia C. Tysoe, Andrew M. Moon, Paul Gibbs, Sally Forrest, Sanjay Sinha, Johannes Bargehr, Daniele Muraro, Sidney A Barritt, William Gelson, Gwilym J. Webb, Eleanor Barnes, Mailis Maes, Stephen Baker, Gareth Corbett, Thomas L Williams, Gordon Dougan, Vasileios Galanakis, Ravindra K. Gupta, Fotios Sampaziotis, Scott Dillon, Ludovic Vallier, Lisa Swift, Teresa Brevini, Andrew J. Butler, Mahnaz Darvish-Damavandi, Sara Upponi, Ansgar W. Lohse, George F. Mells, Kourosh Saeb-Parsy, Simon J.A. Buczacki, Marta Vila-Gonzalez, Victoria L. Mulcahy, Susan E. Davies, Sagar Varankar, Thomas Marjot, Petra Mlcochova, Christopher J.E. Watson, Anthony P. Davenport, Joo-Hyeon Lee, Thomas W M Crozier, Rhoda E. Kuc

مصطلحات موضوعية: Therapeutic approach, Downregulation and upregulation, business.industry, Regulator, Medicine, Farnesoid X receptor, Receptor, business, Bioinformatics, Ursodeoxycholic acid, Ex vivo, Cholangiocyte, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::67bbf5a5471abdb9a98cd836cdc4ceac
https://doi.org/10.1101/2021.06.06.446781

المؤلفون: Matthias Zilbauer, Olivia C. Tysoe, Daniele Muraro, Ludovic Vallier, Carola M. Morell, Nicholas R.F. Hannan, Stuart J. Forbes, Samantha G. Tilson, Richard L. Gieseck, Thomas A. Wynn, Simone E. Adams, Rute A. Tomaz, Brandon T Wesley, Wei-Yu Lu, Judith Kraiczy, John R. Ferdinand, Kourosh Saeb-Parsy, Gabriel C. Oniscu, Alexander Ross, Casey A. Rimland, Francisco Otaizo-Carrasquero, Nikitas Georgakopoulos, Timothy G. Myers, Fotios Sampaziotis

المصدر: Hepatology
Rimland, C A, Tilson, S G, Morell, C M, Tomaz, R A, Lu, W-Y, Adams, S E, Georgakopoulos, N, Otaizo-Carrasquero, F, Myers, T G, Ferdinand, J R, Gieseck, R L, Sampaziotis, F, Tysoe, O C, Wesley, B, Muraro, D, Oniscu, G C, Hannan, N R, Forbes, S J, Saeb-Parsy, K, Wynn, T A & Vallier, L 2020, ' Regional differences in human biliary tissues and corresponding in vitro derived organoids ', Hepatology . https://doi.org/10.1002/hep.31252
Hepatology (Baltimore, Md.)

مصطلحات موضوعية: 0301 basic medicine, Tissue and Organ Procurement, Cellular differentiation, Intrahepatic bile ducts, Biology, Cholangiocyte, 03 medical and health sciences, Mice, 0302 clinical medicine, Liver Injury and Regeneration, Bile Ducts, Extrahepatic, Organoid, medicine, Animals, Bile, Humans, RNA-Seq, Pancreatic duct, Common Bile Duct, Keratin-19, Common bile duct, Hepatology, Gallbladder, Wnt signaling pathway, Cell Differentiation, Epithelial Cells, Original Articles, Cell biology, Organoids, 030104 developmental biology, medicine.anatomical_structure, Bile Ducts, Intrahepatic, Gene Expression Regulation, Liver, 030211 gastroenterology & hepatology, Original Article

وصف الملف: PDF; application/vnd.openxmlformats-officedocument.wordprocessingml.document

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9726cf8011fd07478f790d0cdca21a08

المؤلفون: Sanjay Sinha, Victoria L. Mulcahy, William Gelson, Kourosh Saeb-Parsy, Brandon T Wesley, Sarah A. Teichmann, Laure Gambardella, Timothy E. Beach, Sharayne Robinson, Michael P. Murphy, Paul Gibbs, Stephanie Brown, Richard L. Gieseck, Peter C. Humphreys, Corrina Fear, Anna Osnato, Krishnaa T. Mahbubani, Gareth Corbett, Irum Amin, Olivia C. Tysoe, Daniele Muraro, Christopher J.E. Watson, Espen Melum, Daniel Ortmann, Andrew J. Butler, George F. Mells, Teresa Brevini, Keziah Crick, Sara Upponi, Fotios Sampaziotis, Susan E. Davies, Teik Choon See, Giovanni Canu, Stephen J. Sawiak, Jose Garcia-Bernardo, Edmund Godfrey, Ludovic Vallier, N.L. Berntsen, Lisa Swift, Johannes Bargehr

المساهمون: Sampaziotis, Fotios [0000-0003-0812-7586], Muraro, Daniele [0000-0001-9601-237X], Tysoe, Olivia C [0000-0002-1061-1484], Sawiak, Stephen [0000-0003-4210-9816], Brevini, Teresa [0000-0002-3581-5379], Wesley, Brandon T [0000-0003-0530-329X], Garcia-Bernardo, Jose [0000-0003-3626-5433], Mahbubani, Krishnaa [0000-0002-1327-2334], Canu, Giovanni [0000-0002-3349-4479], Berntsen, Natalie L [0000-0002-5949-8910], Mulcahy, Victoria L [0000-0001-7091-4789], Robinson, Sharayne [0000-0001-6819-3433], Swift, Lisa [0000-0001-9044-688X], Gambardella, Laure [0000-0001-5771-1565], Bargehr, Johannes [0000-0002-9304-3573], Osnato, Anna [0000-0001-5241-1512], Murphy, Michael P [0000-0003-1115-9618], Gibbs, Paul [0000-0003-2193-5377], Sinha, Sanjay [0000-0001-5900-1209], Teichmann, Sarah A [0000-0002-6294-6366], Melum, Espen [0000-0001-6903-6878], Saeb-Parsy, Kourosh [0000-0002-0633-3696], Vallier, Ludovic [0000-0002-3848-2602], Apollo - University of Cambridge Repository

المصدر: Science (New York, N.Y.). 371(6531)

مصطلحات موضوعية: 0301 basic medicine, Tissue and Organ Procurement, medicine.medical_treatment, Cell- and Tissue-Based Therapy, Context (language use), Bile Duct Diseases, Biology, Liver transplantation, Mesenchymal Stem Cell Transplantation, Regenerative medicine, Cholangiocyte, 03 medical and health sciences, Mice, 0302 clinical medicine, In vivo, Organoid, medicine, Animals, Bile, Humans, RNA-Seq, Common Bile Duct, Multidisciplinary, Gallbladder, Epithelial Cells, Cell biology, Liver Transplantation, Transplantation, Organoids, 030104 developmental biology, Bile Ducts, Intrahepatic, Gene Expression Regulation, Liver, 030211 gastroenterology & hepatology, Bile Ducts, Transcriptome, Ex vivo

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f2e06061f52c139f9983e0ff94683d5
https://pubmed.ncbi.nlm.nih.gov/34416748

المؤلفون: Ludovic Vallier, Krishnaa T. Mahbubani, Espen Melum, Alexander W. Justin, Si Emma Chen, Olivia C. Tysoe, Hajer Zedira, Teresa Brevini, Athina E. Markaki, Anna Katharina Frank, Kourosh Saeb-Parsy, Fotios Sampaziotis

المساهمون: Frank, Anna K [0000-0003-1378-5129], Sampaziotis, Fotios [0000-0003-0812-7586], Apollo - University of Cambridge Repository

المصدر: Nature Protocols

مصطلحات موضوعية: medicine.medical_treatment, Biocompatible Materials, Cell Separation, Biology, Liver transplantation, Regenerative medicine, General Biochemistry, Genetics and Molecular Biology, Cholangiocyte, 03 medical and health sciences, Mice, 0302 clinical medicine, Tissue engineering, Organoid, medicine, Animals, Humans, Regeneration, Cells, Cultured, 030304 developmental biology, 0303 health sciences, Tissue Engineering, Tissue Scaffolds, Regeneration (biology), Equipment Design, 3. Good health, Cell biology, Transplantation, Organoids, Bile Ducts, 030217 neurology & neurosurgery, Adult stem cell

وصف الملف: application/pdf; application/vnd.openxmlformats-officedocument.presentationml.presentation

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7a66844d20944107d151c35930937f4c
https://www.repository.cam.ac.uk/handle/1810/293672

المؤلفون: Ludovic Vallier, Fotios Sampaziotis, Olivia C. Tysoe, Teresa Brevini

المصدر: Methods in Molecular Biology ISBN: 9781493994199
Experimental Cholestasis Research
Methods in Molecular Biology
Methods in Molecular Biology-Experimental Cholestasis Research

مصطلحات موضوعية: 0301 basic medicine, Common bile duct, Intrahepatic bile ducts, Biology, Cholangiocyte, 03 medical and health sciences, 0302 clinical medicine, Extrahepatic biliary epithelium, Cholestasis, Endoscopic retrograde cholangiopancreatography, medicine, Organoid, Human pluripotent stem cells, medicine.diagnostic_test, Cholangiocytes, Bile duct, Gallbladder, Liver biopsy, medicine.disease, Cell biology, Organoids, 030104 developmental biology, medicine.anatomical_structure, 030211 gastroenterology & hepatology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d01b14ac84207c38a34d322b58fba109
https://doi.org/10.1007/978-1-4939-9420-5_25