المؤلفون: Ulf Neumann, Mike Ufer, Laura H Jacobson, Marie‐Laure Rouzade‐Dominguez, Gunilla Huledal, Carine Kolly, Rainer M Lüönd, Rainer Machauer, Siem J Veenstra, Konstanze Hurth, Heinrich Rueeger, Marina Tintelnot‐Blomley, Matthias Staufenbiel, Derya R Shimshek, Ludovic Perrot, Wilfried Frieauff, Valerie Dubost, Hilmar Schiller, Barbara Vogg, Karen Beltz, Alexandre Avrameas, Sandrine Kretz, Nicole Pezous, Jean‐Michel Rondeau, Nicolau Beckmann, Andreas Hartmann, Stefan Vormfelde, Olivier J David, Bruno Galli, Rita Ramos, Ana Graf, Cristina Lopez Lopez

المصدر: EMBO Molecular Medicine, Vol 10, Iss 11, Pp n/a-n/a (2018)

مصطلحات موضوعية: Alzheimer's disease, BACE‐1 inhibitor, drug discovery, prevention, β‐amyloid, Medicine (General), R5-920, Genetics, QH426-470

وصف الملف: electronic resource

Relation: https://doaj.org/toc/1757-4676; https://doaj.org/toc/1757-4684

URL الوصول: https://doaj.org/article/48fbf5e81f1a4f18ae40665093c63175

المؤلفون: Olivier Petricoul, Arman Nazarian, Uwe Schuehly, Ursula Schramm, Olivier J. David, Didier Laurent, Jens Praestgaard, Ronenn Roubenoff, Dimitris A. Papanicolaou, Daniel Rooks

المصدر: Clinical pharmacokinetics.

مصطلحات موضوعية: Pharmacology, Pharmacology (medical)

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f014f9a6e2c9589cb74e06620cf92ed
https://pubmed.ncbi.nlm.nih.gov/36527600

المؤلفون: Huixin Yu, Gordon Graham, Olivier J. David, Joseph M. Kahn, Marina Savelieva, Etienne Pigeolet, Ayan Das Gupta, Ratnakar Pingili, Roman Willi, Krishnan Ramanathan, Bernd C. Kieseier, Dieter A. Häring, Morten Bagger, Per Soelberg Sørensen

المصدر: Yu, H, Graham, G, David, O J, Kahn, J M, Savelieva, M, Pigeolet, E, Das Gupta, A, Pingili, R, Willi, R, Ramanathan, K, Kieseier, B C, Häring, D A, Bagger, M & Soelberg Sørensen, P 2022, ' Population Pharmacokinetic–B Cell Modeling for Ofatumumab in Patients with Relapsing Multiple Sclerosis ', CNS Drugs, vol. 36, no. 3, pp. 283-300 . https://doi.org/10.1007/s40263-021-00895-w

مصطلحات موضوعية: Adult, Psychiatry and Mental health, B-Lymphocytes, Multiple Sclerosis, Recurrence, Antibodies, Monoclonal, Humans, Pharmacology (medical), Neurology (clinical), Antibodies, Monoclonal, Humanized

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4cd1a7371f9906632e07d074109cda96
https://curis.ku.dk/portal/da/publications/population-pharmacokineticbcell-modeling-for-ofatumumab-in-patients-with-relapsing-multiple-sclerosis(d6bf6e3c-651f-4327-b794-143666f97dcf).html

المؤلفون: Christian D. Lates, Robert Schmouder, Parasar Pal, Olivier J. David, Hisanori Hara, Rhett Behrje

المصدر: Clinical Pharmacology in Drug Development

مصطلحات موضوعية: Adult, Male, Adolescent, Drug-Related Side Effects and Adverse Reactions, Lymphocyte, Cmax, Pharmaceutical Science, Original Manuscript, Pharmacology, 030226 pharmacology & pharmacy, Drug Administration Schedule, Young Adult, 03 medical and health sciences, 0302 clinical medicine, Therapeutic index, drug‐drug interaction, Pharmacokinetics, medicine, Humans, Drug Interactions, Pharmacology (medical), fingolimod, Dose-Response Relationship, Drug, CYP3A4, Fingolimod Hydrochloride, business.industry, Healthy subjects, Articles, Carbamazepine, Middle Aged, Fingolimod, Healthy Volunteers, medicine.anatomical_structure, Area Under Curve, healthy subjects, Female, business, pharmacokinetics, 030217 neurology & neurosurgery, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::39763ebe16605f902fd3d77319fa78be
https://doi.org/10.1002/cpdd.459

المؤلفون: Tjalf Ziemssen, Amy Berwick, Hisanori Hara, Robert Schmouder, Peng Li, Michael Lang, Olivier J. David, Klaus Tiel-Wilck, Nicole Pezous

المصدر: Clinical Pharmacology in Drug Development

مصطلحات موضوعية: Adult, Male, medicine.medical_specialty, Multiple Sclerosis, Cmax, Pharmaceutical Science, fingolimod‐phosphate, Semen, Gastroenterology, Phosphates, 03 medical and health sciences, 0302 clinical medicine, blood, Internal medicine, medicine, Humans, Pharmacology (medical), 030212 general & internal medicine, fingolimod, Active metabolite, Fetus, Fingolimod Hydrochloride, business.industry, Brief Report, Multiple sclerosis, semen, Middle Aged, medicine.disease, Fingolimod, Safety profile, Male patient, business, Immunosuppressive Agents, 030217 neurology & neurosurgery, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c9f072e77901ffe31d84815bd5905307
https://doi.org/10.1002/cpdd.424

المؤلفون: Maxwell Pryce, Karin Meiser, Franck Picard, Olivier J. David, Robert Schmouder, Corinne Emotte, Valentin Moiseev, Zhanna Kobalava

المصدر: Int. Journal of Clinical Pharmacology and Therapeutics. 53:847-854

مصطلحات موضوعية: Adult, Male, Pharmacology, medicine.medical_specialty, Fingolimod Hydrochloride, business.industry, Cmax, Urine, Middle Aged, Fingolimod, Gastroenterology, Tolerability, Pharmacokinetics, Internal medicine, Anesthesia, medicine, Humans, Female, Pharmacology (medical), Renal Insufficiency, Adverse effect, business, Active metabolite, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::add0227b11f9954f999b9177a9732d42
https://doi.org/10.5414/cp202356

المؤلفون: Valerie Dubost, Bruno Galli, Laura H. Jacobson, Alexandre Avrameas, Wilfried Frieauff, Marie-Laure Rouzade-Dominguez, Konstanze Hurth, Derya R. Shimshek, Ulf Neumann, Nicole Pezous, Ana Graf, Karen Beltz, Jean-Michel Rondeau, Hilmar Schiller, Heinrich Rueeger, Nicolau Beckmann, Siem Jacob Veenstra, Marina Tintelnot-Blomley, Rita Ramos, Sandrine Kretz, Mike Ufer, Rainer Machauer, Stefan Viktor Vormfelde, Cristina Lopez Lopez, Gunilla Huledal, Olivier J. David, Carine Kolly, Andreas Hartmann, Rainer Lüönd, Barbara Vogg, Matthias Staufenbiel, Ludovic Perrot

المصدر: EMBO Molecular Medicine
EMBO Molecular Medicine, Vol 10, Iss 11, Pp n/a-n/a (2018)

مصطلحات موضوعية: 0301 basic medicine, Male, Medicine (General), Pharmacology, QH426-470, Cathepsin D, Translational Research, Biomedical, Amyloid beta-Protein Precursor, 0302 clinical medicine, Cerebrospinal fluid, prevention, Amyloid precursor protein, Aspartic Acid Endopeptidases, News & Views, Microglia, biology, Neurodegeneration, Brain, BACE‐1 inhibitor, Hominidae, Alzheimer's disease, medicine.anatomical_structure, Molecular Medicine, Female, Mice, Transgenic, drug discovery, 03 medical and health sciences, R5-920, Alzheimer Disease, mental disorders, Oxazines, medicine, Genetics, Dementia, Animals, Humans, Pharmacology & Drug Discovery, Cerebral Hemorrhage, Inflammation, business.industry, medicine.disease, Mice, Inbred C57BL, 030104 developmental biology, Astrocytes, biology.protein, Verubecestat, β‐amyloid, Amyloid Precursor Protein Secretases, business, Amyloid precursor protein secretase, 030217 neurology & neurosurgery, Neuroscience

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::01044e86b3672f81bb8e9b69d171d1be
https://pubmed.ncbi.nlm.nih.gov/30322841

المؤلفون: Robert Schmouder, Stephan J. Schreiber, Olivier J. David, Karin Meiser, Uwe Pleyer, Magdalena Ocwieja, Jessica V. Valencia, Sabine Ziemer, Frank Wagner

المصدر: British Journal of Clinical Pharmacology. 78:1354-1365

مصطلحات موضوعية: Pharmacology, medicine.medical_specialty, business.industry, Multiple sclerosis, Blood flow, medicine.disease, Placebo, Fingolimod, Cerebral blood flow, medicine.artery, Fingolimod Hydrochloride, Ophthalmology, Pharmacodynamics, Anesthesia, Middle cerebral artery, medicine, Pharmacology (medical), business, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::f21d6a9fb1772cbb81cbd708818547f1
https://doi.org/10.1111/bcp.12454

المؤلفون: Carine Kolly, Marie-Laure Rouzade-Dominguez, Gabriel Vargas, Cristina Lopez-Lopez, Ulf Neumann, Nicole Pezous, Mike Ufer, Olivier J. David, Robert A. Lenz, Ana Graf, Pierre N. Tariot, Eric M. Reiman

المصدر: Alzheimer's & Dementia. 13

مصطلحات موضوعية: Gerontology, medicine.medical_specialty, Epidemiology, business.industry, Health Policy, Alternative medicine, Psychiatry and Mental health, Cellular and Molecular Neuroscience, Developmental Neuroscience, Medicine, Medical physics, Neurology (clinical), Geriatrics and Gerontology, business, Dose selection

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::bc63ec057985461f0f9c0f4e6f931c17
https://doi.org/10.1016/j.jalz.2017.07.245

المؤلفون: Olivier J. David, Karin Meiser, Craig Boulton, Robert Schmouder

المصدر: Clinical Pharmacology in Drug Development. 2:2-10

مصطلحات موضوعية: medicine.medical_specialty, Exacerbation, business.industry, medicine.drug_class, Pharmaceutical Science, Placebo, medicine.disease, Gastroenterology, Fingolimod, Pulmonary function testing, Tolerability, Pharmacodynamics, Bronchodilator, Internal medicine, Anesthesia, Medicine, Pharmacology (medical), business, medicine.drug, Asthma

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::449f9aefa2a30b6bd1933f13a58029fe
https://doi.org/10.1002/cpdd.4