المؤلفون: Chan C; Center for Translational Immunology, University Medical Center Utrecht, Utrecht, the Netherlands., Jansen JHM; Center for Translational Immunology, University Medical Center Utrecht, Utrecht, the Netherlands., Hendriks IST; Center for Translational Immunology, University Medical Center Utrecht, Utrecht, the Netherlands., van der Peet IC; Center for Translational Immunology, University Medical Center Utrecht, Utrecht, the Netherlands., Verdonschot MEL; Center for Translational Immunology, University Medical Center Utrecht, Utrecht, the Netherlands., Passchier EM; Center for Translational Immunology, University Medical Center Utrecht, Utrecht, the Netherlands., Tsioumpekou M; Center for Translational Immunology, University Medical Center Utrecht, Utrecht, the Netherlands., Nederend M; Center for Translational Immunology, University Medical Center Utrecht, Utrecht, the Netherlands., Klomp SA; Center for Translational Immunology, University Medical Center Utrecht, Utrecht, the Netherlands., Valerius T; Division of Stem Cell Transplantation and Immunotherapy, Department of Medicine II, Christian-Al-brechts University Kiel and University Medical Center Schleswig-Holstein, Campus Kiel, Kiel, Germany., Peipp M; Division of Antibody-Based Immunotherapy, Department of Medicine II, Christian Albrechts University Kiel and University Medical Center Schleswig-Holstein, Campus Kiel, Kiel, Germany., Leusen JHW; Center for Translational Immunology, University Medical Center Utrecht, Utrecht, the Netherlands., Olofsen PA; Center for Translational Immunology, University Medical Center Utrecht, Utrecht, the Netherlands.

المصدر: Molecular cancer therapeutics [Mol Cancer Ther] 2024 Sep 04; Vol. 23 (9), pp. 1317-1331.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: American Association for Cancer Research, Inc Country of Publication: United States NLM ID: 101132535 Publication Model: Print Cited Medium: Internet ISSN: 1538-8514 (Electronic) Linking ISSN: 15357163 NLM ISO Abbreviation: Mol Cancer Ther Subsets: MEDLINE

مواضيع طبية MeSH: ErbB Receptors*/antagonists & inhibitors , ErbB Receptors*/immunology , Neutrophils*/immunology , Neutrophils*/drug effects , Neutrophils*/metabolism , Antibody-Dependent Cell Cytotoxicity*/immunology , Antibody-Dependent Cell Cytotoxicity*/drug effects, Humans ; Animals ; Mice ; Cell Line, Tumor ; Xenograft Model Antitumor Assays ; Immunoglobulin Fc Fragments/immunology ; Immunoglobulin Fc Fragments/pharmacology ; Immunoglobulin A/immunology ; Antibodies, Monoclonal/pharmacology ; Antibodies, Monoclonal/therapeutic use ; Antineoplastic Agents, Immunological/pharmacology ; Protein Engineering ; Antibodies, Monoclonal, Humanized/pharmacology ; Antibodies, Monoclonal, Humanized/therapeutic use ; Female

المؤلفون: Raymakers L; Center for Translational Immunology, University Medical Center Utrecht, Utrecht, The Netherlands; Department of Radiation Oncology, University Medical Center Utrecht, UMC Utrecht Cancer Center, Utrecht, The Netherlands., Demmers TJ; Center for Translational Immunology, University Medical Center Utrecht, Utrecht, The Netherlands., Meijer GJ; Department of Radiation Oncology, University Medical Center Utrecht, UMC Utrecht Cancer Center, Utrecht, The Netherlands., Molenaar IQ; Department of Surgery, Regional Academic Cancer Center Utrecht, UMC Utrecht Cancer Center and St. Antonius Hospital Nieuwegein, Utrecht University, Utrecht, The Netherlands., van Santvoort HC; Department of Surgery, Regional Academic Cancer Center Utrecht, UMC Utrecht Cancer Center and St. Antonius Hospital Nieuwegein, Utrecht University, Utrecht, The Netherlands., Intven MPW; Department of Radiation Oncology, University Medical Center Utrecht, UMC Utrecht Cancer Center, Utrecht, The Netherlands., Leusen JHW; Center for Translational Immunology, University Medical Center Utrecht, Utrecht, The Netherlands., Olofsen PA; Center for Translational Immunology, University Medical Center Utrecht, Utrecht, The Netherlands., Daamen LA; Department of Radiation Oncology, University Medical Center Utrecht, UMC Utrecht Cancer Center, Utrecht, The Netherlands; Department of Surgery, Regional Academic Cancer Center Utrecht, UMC Utrecht Cancer Center and St. Antonius Hospital Nieuwegein, Utrecht University, Utrecht, The Netherlands. Electronic address: l.a.daamen-3@umcutrecht.nl.

المصدر: International journal of radiation oncology, biology, physics [Int J Radiat Oncol Biol Phys] 2024 Jul 14. Date of Electronic Publication: 2024 Jul 14.

نوع المنشور: Journal Article; Review

بيانات الدورية: Publisher: Elsevier, Inc Country of Publication: United States NLM ID: 7603616 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-355X (Electronic) Linking ISSN: 03603016 NLM ISO Abbreviation: Int J Radiat Oncol Biol Phys Subsets: MEDLINE

المؤلفون: Stip MC; Center for Translational Immunology, UMC Utrecht, Heidelberglaan 100, 3584 CX, Utrecht, The Netherlands., Jansen JHM; Center for Translational Immunology, UMC Utrecht, Heidelberglaan 100, 3584 CX, Utrecht, The Netherlands., Nederend M; Center for Translational Immunology, UMC Utrecht, Heidelberglaan 100, 3584 CX, Utrecht, The Netherlands., Tsioumpekou M; Center for Translational Immunology, UMC Utrecht, Heidelberglaan 100, 3584 CX, Utrecht, The Netherlands., Evers M; Center for Translational Immunology, UMC Utrecht, Heidelberglaan 100, 3584 CX, Utrecht, The Netherlands., Olofsen PA; Center for Translational Immunology, UMC Utrecht, Heidelberglaan 100, 3584 CX, Utrecht, The Netherlands., Meyer-Wentrup F; Princess Máxima Center for Pediatric Oncology, Heidelberglaan 25, 3584 CS, Utrecht, The Netherlands., Leusen JHW; Center for Translational Immunology, UMC Utrecht, Heidelberglaan 100, 3584 CX, Utrecht, The Netherlands. j.h.w.leusen@umcutrecht.nl.

المصدر: Cancer immunology, immunotherapy : CII [Cancer Immunol Immunother] 2023 Sep; Vol. 72 (9), pp. 3063-3077. Date of Electronic Publication: 2023 Jun 20.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Springer Verlag Country of Publication: Germany NLM ID: 8605732 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1432-0851 (Electronic) Linking ISSN: 03407004 NLM ISO Abbreviation: Cancer Immunol Immunother Subsets: MEDLINE

مواضيع طبية MeSH: Immunoglobulin A*/metabolism , Neoplasms*, Mice ; Humans ; Male ; Female ; Animals ; Mice, Transgenic ; Mice, SCID ; Mice, Inbred C57BL ; Receptors, Fc

المؤلفون: Tsioumpekou M; Center for Translational Immunology, University Medical Center Utrecht, 3584 CX Utrecht, The Netherlands., Krijgsman D; Center for Translational Immunology, University Medical Center Utrecht, 3584 CX Utrecht, The Netherlands.; Center for Molecular Medicine, University Medical Center Utrecht, 3584 CX Utrecht, The Netherlands., Leusen JHW; Center for Translational Immunology, University Medical Center Utrecht, 3584 CX Utrecht, The Netherlands., Olofsen PA; Center for Translational Immunology, University Medical Center Utrecht, 3584 CX Utrecht, The Netherlands.

المصدر: Cells [Cells] 2023 Jul 31; Vol. 12 (15). Date of Electronic Publication: 2023 Jul 31.

نوع المنشور: Journal Article; Review

بيانات الدورية: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101600052 Publication Model: Electronic Cited Medium: Internet ISSN: 2073-4409 (Electronic) Linking ISSN: 20734409 NLM ISO Abbreviation: Cells Subsets: MEDLINE

المؤلفون: Olofsen PA; Department of Hematology, Erasmus University Medical Center, Rotterdam, the Netherlands., Bosch DA; Department of Hematology, Erasmus University Medical Center, Rotterdam, the Netherlands., de Looper HWJ; Department of Hematology, Erasmus University Medical Center, Rotterdam, the Netherlands., van Strien PMH; Department of Hematology, Erasmus University Medical Center, Rotterdam, the Netherlands., Hoogenboezem RM; Department of Hematology, Erasmus University Medical Center, Rotterdam, the Netherlands., Roovers O; Department of Hematology, Erasmus University Medical Center, Rotterdam, the Netherlands., van der Velden VHJ; Department of Immunology, Erasmus University Medical Center, Rotterdam, the Netherlands., Bindels EMJ; Department of Hematology, Erasmus University Medical Center, Rotterdam, the Netherlands., De Pater EM; Department of Hematology, Erasmus University Medical Center, Rotterdam, the Netherlands., Touw IP; Department of Hematology, Erasmus University Medical Center, Rotterdam, the Netherlands.

المصدر: British journal of haematology [Br J Haematol] 2023 Jan; Vol. 200 (1), pp. 79-86. Date of Electronic Publication: 2022 Sep 28.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Wiley-Blackwell Country of Publication: England NLM ID: 0372544 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1365-2141 (Electronic) Linking ISSN: 00071048 NLM ISO Abbreviation: Br J Haematol Subsets: MEDLINE

مواضيع طبية MeSH: Leukemia, Myeloid, Acute*/diagnosis , Myelodysplastic Syndromes*/genetics , Myelodysplastic Syndromes*/complications, Mice ; Animals ; Congenital Bone Marrow Failure Syndromes/genetics ; Mutation

SCR Disease Name: Neutropenia, Severe Congenital, Autosomal Recessive 3

المؤلفون: Olofsen PA; Center for Translational Immunology, University Medical Center Utrecht, 3584 CX Utrecht, The Netherlands., Stip MC; Center for Translational Immunology, University Medical Center Utrecht, 3584 CX Utrecht, The Netherlands., Jansen JHM; Center for Translational Immunology, University Medical Center Utrecht, 3584 CX Utrecht, The Netherlands., Chan C; Center for Translational Immunology, University Medical Center Utrecht, 3584 CX Utrecht, The Netherlands., Nederend M; Center for Translational Immunology, University Medical Center Utrecht, 3584 CX Utrecht, The Netherlands., Tieland RG; Center for Translational Immunology, University Medical Center Utrecht, 3584 CX Utrecht, The Netherlands., Tsioumpekou M; Center for Translational Immunology, University Medical Center Utrecht, 3584 CX Utrecht, The Netherlands., Leusen JHW; Center for Translational Immunology, University Medical Center Utrecht, 3584 CX Utrecht, The Netherlands.

المصدر: Cells [Cells] 2022 Oct 27; Vol. 11 (21). Date of Electronic Publication: 2022 Oct 27.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101600052 Publication Model: Electronic Cited Medium: Internet ISSN: 2073-4409 (Electronic) Linking ISSN: 20734409 NLM ISO Abbreviation: Cells Subsets: MEDLINE

مواضيع طبية MeSH: Neutrophils*/metabolism , Antigens, Ly*/metabolism, Mice ; Animals ; Mice, SCID ; Antibodies, Monoclonal/metabolism ; Mice, Inbred C57BL ; Mice, Inbred BALB C

المؤلفون: Olofsen PA; Department of Hematology., Bosch DA; Department of Hematology., Roovers O; Department of Hematology., van Strien PMH; Department of Hematology., de Looper HWJ; Department of Hematology., Hoogenboezem RM; Department of Hematology., Barnhoorn S; Department of Molecular Genetics., Mastroberardino PG; Department of Molecular Genetics., Ghazvini M; Department of Developmental Biology, iPS Core Facility, and., van der Velden VHJ; Department of Immunology, Erasmus University Medical Center, Rotterdam, The Netherlands., Bindels EMJ; Department of Hematology., de Pater EM; Department of Hematology., Touw IP; Department of Hematology.

المصدر: Blood advances [Blood Adv] 2021 Feb 09; Vol. 5 (3), pp. 775-786.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: American Society of Hematology Country of Publication: United States NLM ID: 101698425 Publication Model: Print Cited Medium: Internet ISSN: 2473-9537 (Electronic) Linking ISSN: 24739529 NLM ISO Abbreviation: Blood Adv Subsets: MEDLINE

مواضيع طبية MeSH: Neutropenia*/congenital , Neutropenia*/genetics, Leukocyte Elastase/*genetics, Adaptor Proteins, Signal Transducing ; Congenital Bone Marrow Failure Syndromes ; Granulocyte Colony-Stimulating Factor ; Humans ; Mutation

SCR Disease Name: Neutropenia, Severe Congenital, Autosomal Recessive 3

المؤلفون: Schmied L; Division of Hematology and.; Division of Internal Medicine, University Hospital Basel, Basel, Switzerland., Olofsen PA; Department of Hematology, Erasmus University Medical Center, Rotterdam, The Netherlands., Lundberg P; Division of Hematology and., Tzankov A; Division of Pathology, University Hospital Basel, Basel, Switzerland; and., Kleber M; Division of Hematology and.; Division of Internal Medicine, University Hospital Basel, Basel, Switzerland., Halter J; Division of Hematology and., Uhr M; Division of Hematology, Moncucco Hospital Lugano, Lugano, Switzerland., Valk PJM; Department of Hematology, Erasmus University Medical Center, Rotterdam, The Netherlands., Touw IP; Department of Hematology, Erasmus University Medical Center, Rotterdam, The Netherlands., Passweg J; Division of Hematology and., Drexler B; Division of Hematology and.

المصدر: Blood advances [Blood Adv] 2020 Nov 10; Vol. 4 (21), pp. 5540-5546.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: American Society of Hematology Country of Publication: United States NLM ID: 101698425 Publication Model: Print Cited Medium: Internet ISSN: 2473-9537 (Electronic) Linking ISSN: 24739529 NLM ISO Abbreviation: Blood Adv Subsets: MEDLINE

مواضيع طبية MeSH: Anemia, Aplastic* , Leukemia, Myeloid, Acute*/genetics , Neutropenia*, Congenital Bone Marrow Failure Syndromes ; Humans ; Mutation

المؤلفون: Olofsen PA; Department of Hematology, Erasmus University Medical Center, Rotterdam 3015 CN, the Netherlands., Fatrai S; Department of Hematology, Erasmus University Medical Center, Rotterdam 3015 CN, the Netherlands., van Strien PMH; Department of Hematology, Erasmus University Medical Center, Rotterdam 3015 CN, the Netherlands., Obenauer JC; Department of Hematology, Erasmus University Medical Center, Rotterdam 3015 CN, the Netherlands., de Looper HWJ; Department of Hematology, Erasmus University Medical Center, Rotterdam 3015 CN, the Netherlands., Hoogenboezem RM; Department of Hematology, Erasmus University Medical Center, Rotterdam 3015 CN, the Netherlands., Erpelinck-Verschueren CAJ; Department of Hematology, Erasmus University Medical Center, Rotterdam 3015 CN, the Netherlands., Vermeulen MPWM; Department of Hematology, Erasmus University Medical Center, Rotterdam 3015 CN, the Netherlands., Roovers O; Department of Hematology, Erasmus University Medical Center, Rotterdam 3015 CN, the Netherlands., Haferlach T; Munich Leukemia Laboratory (MLL), Munich 81377, Germany., Jansen JH; Department of Laboratory Medicine, Radboud University Medical Center, Nijmegen 6525 GA, the Netherlands., Ghazvini M; Department of Developmental Biology, iPS Core Facility, Erasmus University Medical Center, Rotterdam 3015 CN, the Netherlands., Bindels EMJ; Department of Hematology, Erasmus University Medical Center, Rotterdam 3015 CN, the Netherlands., Schneider RK; Department of Hematology, Erasmus University Medical Center, Rotterdam 3015 CN, the Netherlands., de Pater EM; Department of Hematology, Erasmus University Medical Center, Rotterdam 3015 CN, the Netherlands., Touw IP; Department of Hematology, Erasmus University Medical Center, Rotterdam 3015 CN, the Netherlands.

المصدر: Cell reports. Medicine [Cell Rep Med] 2020 Aug 25; Vol. 1 (5), pp. 100074. Date of Electronic Publication: 2020 Aug 25 (Print Publication: 2020).

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Cell Press Country of Publication: United States NLM ID: 101766894 Publication Model: eCollection Cited Medium: Internet ISSN: 2666-3791 (Electronic) Linking ISSN: 26663791 NLM ISO Abbreviation: Cell Rep Med

مواضيع طبية MeSH: Cell Transformation, Neoplastic/*genetics , Congenital Bone Marrow Failure Syndromes/*genetics , Congenital Bone Marrow Failure Syndromes/*pathology , DNA-Binding Proteins/*genetics , Leukemia, Myeloid, Acute/*genetics , Leukemia, Myeloid, Acute/*pathology , Mutation/*genetics , Neutropenia/*congenital , Transcription Factors/*genetics, Animals ; Cell Line ; Cell Line, Tumor ; Cell Transformation, Neoplastic/pathology ; Core Binding Factor Alpha 2 Subunit/genetics ; HEK293 Cells ; Humans ; Inflammation/genetics ; Inflammation/pathology ; K562 Cells ; Mice ; Neutropenia/genetics ; Neutropenia/pathology ; Signal Transduction/genetics

SCR Disease Name: Neutropenia, Severe Congenital, Autosomal Recessive 3

المؤلفون: Olofsen PA; Department of Hematology, Erasmus MC, Rotterdam 3015 CN, The Netherlands., Touw IP; Department of Hematology, Erasmus MC, Rotterdam 3015 CN, The Netherlands.

المصدر: Molecules and cells [Mol Cells] 2020 Feb 29; Vol. 43 (2), pp. 139-144.

نوع المنشور: Journal Article; Review

بيانات الدورية: Publisher: Elsevier Country of Publication: United States NLM ID: 9610936 Publication Model: Print Cited Medium: Internet ISSN: 0219-1032 (Electronic) Linking ISSN: 10168478 NLM ISO Abbreviation: Mol Cells Subsets: MEDLINE

مواضيع طبية MeSH: Congenital Bone Marrow Failure Syndromes/*etiology , Core Binding Factor Alpha 2 Subunit/*genetics , Leukemia, Myeloid, Acute/*complications , Neutropenia/*congenital, Congenital Bone Marrow Failure Syndromes/pathology ; Disease Progression ; Humans ; Leukemia, Myeloid, Acute/pathology ; Mutation ; Neutropenia/etiology ; Neutropenia/pathology

SCR Disease Name: Neutropenia, Severe Congenital, Autosomal Recessive 3