المؤلفون: Yao F; Cancer Therapeutics and Stratified Oncology, Genome Institute of Singapore, Singapore 138672, Singapore; The Singapore Gastric Cancer Consortium, National University of Singapore, Singapore 119228, Singapore., Kausalya JP; Epithelial Cell Biology Laboratory, Institute of Molecular and Cell Biology, Singapore 138673, Singapore., Sia YY; Cancer Therapeutics and Stratified Oncology, Genome Institute of Singapore, Singapore 138672, Singapore; The Singapore Gastric Cancer Consortium, National University of Singapore, Singapore 119228, Singapore., Teo AS; Cancer Therapeutics and Stratified Oncology, Genome Institute of Singapore, Singapore 138672, Singapore; The Singapore Gastric Cancer Consortium, National University of Singapore, Singapore 119228, Singapore., Lee WH; Computational and Systems Biology, Genome Institute of Singapore, Singapore 138672, Singapore., Ong AG; Epithelial Cell Biology Laboratory, Institute of Molecular and Cell Biology, Singapore 138673, Singapore., Zhang Z; Human Genetics, Genome Institute of Singapore, Singapore 138672, Singapore., Tan JH; Cancer Therapeutics and Stratified Oncology, Genome Institute of Singapore, Singapore 138672, Singapore., Li G; National Key Laboratory of Crop Genetic Improvement, Center for Bioinformatics, College of Informatics, Huazhong Agricultural University, Wuhan 430070, China., Bertrand D; Computational and Systems Biology, Genome Institute of Singapore, Singapore 138672, Singapore., Liu X; Cancer Therapeutics and Stratified Oncology, Genome Institute of Singapore, Singapore 138672, Singapore., Poh HM; Cancer Therapeutics and Stratified Oncology, Genome Institute of Singapore, Singapore 138672, Singapore., Guan P; Computational and Systems Biology, Genome Institute of Singapore, Singapore 138672, Singapore; School of Computing, National University of Singapore, Singapore 117417, Singapore., Zhu F; The Singapore Gastric Cancer Consortium, National University of Singapore, Singapore 119228, Singapore; Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore 119228, Singapore., Pathiraja TN; Cancer Therapeutics and Stratified Oncology, Genome Institute of Singapore, Singapore 138672, Singapore; The Singapore Gastric Cancer Consortium, National University of Singapore, Singapore 119228, Singapore., Ariyaratne PN; Computational and Systems Biology, Genome Institute of Singapore, Singapore 138672, Singapore., Rao J; Department of General Surgery, Tan Tock Seng Hospital, Singapore 308433, Singapore., Woo XY; Personal Genomic Solutions, Genome Institute of Singapore, Singapore 138672, Singapore., Cai S; Computational and Systems Biology, Genome Institute of Singapore, Singapore 138672, Singapore., Mulawadi FH; Computational and Systems Biology, Genome Institute of Singapore, Singapore 138672, Singapore., Poh WT; Personal Genomic Solutions, Genome Institute of Singapore, Singapore 138672, Singapore., Veeravalli L; Research Computing, Genome Institute of Singapore, Singapore 138672, Singapore., Chan CS; Research Computing, Genome Institute of Singapore, Singapore 138672, Singapore., Lim SS; Human Genetics, Genome Institute of Singapore, Singapore 138672, Singapore., Leong ST; Genome Technology and Biology, Genome Institute of Singapore, Singapore 138672, Singapore., Neo SC; Genome Technology and Biology, Genome Institute of Singapore, Singapore 138672, Singapore., Choi PS; Genome Technology and Biology, Genome Institute of Singapore, Singapore 138672, Singapore., Chew EG; Cancer Therapeutics and Stratified Oncology, Genome Institute of Singapore, Singapore 138672, Singapore., Nagarajan N; Computational and Systems Biology, Genome Institute of Singapore, Singapore 138672, Singapore., Jacques PÉ; Département de Biologie, Université de Sherbrooke, Sherbrooke, QC J1K 2R1, Canada., So JB; The Singapore Gastric Cancer Consortium, National University of Singapore, Singapore 119228, Singapore; Department of Surgery, Yong Loo Lin School of Medicine, National University of Singapore, Singapore 119228, Singapore; National University Health System, Singapore 119228, Singapore., Ruan X; Personal Genomic Solutions, Genome Institute of Singapore, Singapore 138672, Singapore; Genome Technology and Biology, Genome Institute of Singapore, Singapore 138672, Singapore., Yeoh KG; The Singapore Gastric Cancer Consortium, National University of Singapore, Singapore 119228, Singapore; Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore 119228, Singapore; National University Health System, Singapore 119228, Singapore., Tan P; Cancer Therapeutics and Stratified Oncology, Genome Institute of Singapore, Singapore 138672, Singapore; The Singapore Gastric Cancer Consortium, National University of Singapore, Singapore 119228, Singapore; Duke-NUS Graduate Medical School, Singapore 169857, Singapore; Cancer Science Institute of Singapore, Yong Loo Lin School of Medicine, National University of Singapore, Singapore 117599, Singapore., Sung WK; Computational and Systems Biology, Genome Institute of Singapore, Singapore 138672, Singapore; School of Computing, National University of Singapore, Singapore 117417, Singapore., Hunziker W; Epithelial Cell Biology Laboratory, Institute of Molecular and Cell Biology, Singapore 138673, Singapore; Department of Physiology, National University of Singapore, Singapore 117597, Singapore. Electronic address: hunziker@imcb.a-star.edu.sg., Ruan Y; The Jackson Laboratory for Genomic Medicine, Farmington, CT 06032, USA. Electronic address: yijun.ruan@jax.org., Hillmer AM; Cancer Therapeutics and Stratified Oncology, Genome Institute of Singapore, Singapore 138672, Singapore; The Singapore Gastric Cancer Consortium, National University of Singapore, Singapore 119228, Singapore. Electronic address: hillmer@gis.a-star.edu.sg.

المصدر: Cell reports [Cell Rep] 2015 Jul 14; Vol. 12 (2), pp. 272-85. Date of Electronic Publication: 2015 Jul 02.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Cell Press Country of Publication: United States NLM ID: 101573691 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2211-1247 (Electronic) NLM ISO Abbreviation: Cell Rep Subsets: MEDLINE

مواضيع طبية MeSH: Claudins/*genetics , GTPase-Activating Proteins/*genetics , Oncogene Proteins, Fusion/*metabolism , Stomach Neoplasms/*pathology, Amino Acid Sequence ; Animals ; Cell Adhesion ; Cell Line, Tumor ; Cell Movement ; Cell Proliferation ; Clathrin/pharmacology ; Claudins/metabolism ; Dogs ; Endocytosis/drug effects ; Epithelial Cells/cytology ; Epithelial Cells/metabolism ; Epithelial-Mesenchymal Transition ; GTPase-Activating Proteins/metabolism ; HeLa Cells ; Humans ; MCF-7 Cells ; Madin Darby Canine Kidney Cells ; Molecular Sequence Data ; Oncogene Proteins, Fusion/genetics ; Phenotype ; Stomach Neoplasms/metabolism ; rhoA GTP-Binding Protein/antagonists & inhibitors ; rhoA GTP-Binding Protein/metabolism