المؤلفون: Rhett JM, Ongstad EL, Jourdan J, Gourdie RG, Rhett, J Matthew, Ongstad, Emily L, Jourdan, Jane, Gourdie, Robert G

المصدر: Journal of Membrane Biology; Jul2012, Vol. 245 Issue 7, p411-422, 12p

المؤلفون: Vilahur G; Research Institute, Hospital de la Santa Creu i Sant Pau, IIB-Sant Pau, C/Sant Antoni Mª Claret 167, Barcelona 08025, Spain.; Centro de Investigación Biomédica en Red Cardiovascular (CIBERCV), Instituto de Salud Carlos III, Madrid, Spain., Radike M; Research Institute, Hospital de la Santa Creu i Sant Pau, IIB-Sant Pau, C/Sant Antoni Mª Claret 167, Barcelona 08025, Spain.; Radiology Department, Liverpool Heart and Chest Hospital NHS Foundation Trust, Liverpool, UK., Sutelman P; Research Institute, Hospital de la Santa Creu i Sant Pau, IIB-Sant Pau, C/Sant Antoni Mª Claret 167, Barcelona 08025, Spain., Ben-Aicha S; Research Institute, Hospital de la Santa Creu i Sant Pau, IIB-Sant Pau, C/Sant Antoni Mª Claret 167, Barcelona 08025, Spain., Gutiérrez M; Research Institute, Hospital de la Santa Creu i Sant Pau, IIB-Sant Pau, C/Sant Antoni Mª Claret 167, Barcelona 08025, Spain., Casaní L; Research Institute, Hospital de la Santa Creu i Sant Pau, IIB-Sant Pau, C/Sant Antoni Mª Claret 167, Barcelona 08025, Spain., Hovdal D; DMPK, Research and Early Development, Cardiovascular, Renal and Metabolism, BioPharmaceuticals R&D, AstraZeneca, Gothenburg, Sweden., Ongstad EL; Bioscience Cardiovascular, Research and Early Development, Cardiovascular, Renal and Metabolism, BioPharmaceuticals R&D, AstraZeneca, Gaithersburg, MD, USA., Gabrielsen A; Early Clinical Development, Research and Early Development, Cardiovascular, Renal and Metabolism, BioPharmaceuticals R&D, AstraZeneca, Gothenburg, Sweden., Hidalgo A; Radiology Department, Hospital Josep Trueta, Girona, Spain., Fjellström O; Projects, Research and Early Development, Cardiovascular, Renal and Metabolism, BioPharmaceuticals R&D, AstraZeneca, Gothenburg, Sweden., Carlsson L; Bioscience Cardiovascular, Research and Early Development, Cardiovascular, Renal and Metabolism, BioPharmaceuticals R&D, AstraZeneca, Gaithersburg, MD, USA., Badimon L; Research Institute, Hospital de la Santa Creu i Sant Pau, IIB-Sant Pau, C/Sant Antoni Mª Claret 167, Barcelona 08025, Spain.; Centro de Investigación Biomédica en Red Cardiovascular (CIBERCV), Instituto de Salud Carlos III, Madrid, Spain.

المصدر: European heart journal [Eur Heart J] 2024 May 07; Vol. 45 (17), pp. 1553-1567.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Oxford University Press Country of Publication: England NLM ID: 8006263 Publication Model: Print Cited Medium: Internet ISSN: 1522-9645 (Electronic) Linking ISSN: 0195668X NLM ISO Abbreviation: Eur Heart J Subsets: MEDLINE

مواضيع طبية MeSH: Apyrase*/metabolism , Myocardial Infarction*/drug therapy , Ticagrelor*/pharmacology , Ticagrelor*/therapeutic use , Adenosine Triphosphatases*/pharmacology , Adenosine Triphosphatases*/therapeutic use, Animals ; Humans ; Male ; Adenosine/analogs & derivatives ; Adenosine/pharmacology ; Antigens, CD ; Cardiotonic Agents/pharmacology ; Cardiotonic Agents/therapeutic use ; Disease Models, Animal ; Platelet Aggregation/drug effects ; Recombinant Proteins/pharmacology ; Recombinant Proteins/therapeutic use ; Swine

المؤلفون: Florida EM; Section of Inflammation and Cardiometabolic Diseases National Heart, Lung, and Blood Institute, National Institutes of Health Bethesda MD USA., Li H; Section of Inflammation and Cardiometabolic Diseases National Heart, Lung, and Blood Institute, National Institutes of Health Bethesda MD USA., Hong CG; Section of Inflammation and Cardiometabolic Diseases National Heart, Lung, and Blood Institute, National Institutes of Health Bethesda MD USA., Ongstad EL; Bioscience Cardiovascular, Research and Early Development, Cardiovascular, Renal, and Metabolism (CVRM), BioPharmaceuticals R&D, AstraZeneca Gaithersburg MD USA., Gaddipati R; Bioscience Cardiovascular, Research and Early Development, Cardiovascular, Renal, and Metabolism (CVRM), BioPharmaceuticals R&D, AstraZeneca Gaithersburg MD USA., Sitaula S; Bioscience Cardiovascular, Research and Early Development, Cardiovascular, Renal, and Metabolism (CVRM), BioPharmaceuticals R&D, AstraZeneca Gaithersburg MD USA., Varma V; Translational Science and Experimental Medicine, Research and Early Development, Cardiovascular, Renal, and Metabolism (CVRM), BioPharmaceuticals R&D, AstraZeneca Gaithersburg MD USA., Parel PM; Section of Inflammation and Cardiometabolic Diseases National Heart, Lung, and Blood Institute, National Institutes of Health Bethesda MD USA., O'Hagan R; Section of Inflammation and Cardiometabolic Diseases National Heart, Lung, and Blood Institute, National Institutes of Health Bethesda MD USA., Chen MY; Section of Inflammation and Cardiometabolic Diseases National Heart, Lung, and Blood Institute, National Institutes of Health Bethesda MD USA., Teague HL; Section of Inflammation and Cardiometabolic Diseases National Heart, Lung, and Blood Institute, National Institutes of Health Bethesda MD USA., Playford MP; Section of Inflammation and Cardiometabolic Diseases National Heart, Lung, and Blood Institute, National Institutes of Health Bethesda MD USA., Karathanasis SK; NeoProgen Baltimore MD USA.; Section of Lipoprotein Metabolism, Translational Vascular Medicine Branch, National Heart Lung and Blood Institute, National Institutes of Health Bethesda MD USA., Collén A; Projects, Research and Early Development, Cardiovascular, Renal, and Metabolism (CVRM), BioPharmaceuticals R&D, AstraZeneca Gaithersburg MD USA., Mehta NN; Section of Inflammation and Cardiometabolic Diseases National Heart, Lung, and Blood Institute, National Institutes of Health Bethesda MD USA., Remaley AT; Section of Lipoprotein Metabolism, Translational Vascular Medicine Branch, National Heart Lung and Blood Institute, National Institutes of Health Bethesda MD USA., Sorokin AV; Section of Inflammation and Cardiometabolic Diseases National Heart, Lung, and Blood Institute, National Institutes of Health Bethesda MD USA.

المصدر: Journal of the American Heart Association [J Am Heart Assoc] 2023 Nov 20, pp. e031227. Date of Electronic Publication: 2023 Nov 20.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Wiley-Blackwell Country of Publication: England NLM ID: 101580524 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2047-9980 (Electronic) Linking ISSN: 20479980 NLM ISO Abbreviation: J Am Heart Assoc Subsets: MEDLINE

المؤلفون: Sorokin AV; Section of Inflammation and Cardiometabolic Diseases, Cardiovascular Branch., Hong CG; Section of Inflammation and Cardiometabolic Diseases, Cardiovascular Branch., Aponte AM; Proteomics Core, and., Florida EM; Section of Inflammation and Cardiometabolic Diseases, Cardiovascular Branch., Tang J; Section of Lipoprotein Metabolism, Translational Vascular Medicine Branch, National Heart, Lung, and Blood Institute, NIH, Bethesda, Maryland, USA., Patel N; Section of Inflammation and Cardiometabolic Diseases, Cardiovascular Branch., Baranova IN; Department of Laboratory Medicine, Clinical Center, NIH, Bethesda, Maryland, USA., Li H; Section of Inflammation and Cardiometabolic Diseases, Cardiovascular Branch., Parel PM; Section of Inflammation and Cardiometabolic Diseases, Cardiovascular Branch., Chen V; Bioinformatics/Integrated Data Sciences Section, Research Technology Branch, National Institute of Allergy and Infectious Diseases, NIH, Bethesda, Maryland, USA., Wilson SR; Section of Lipoprotein Metabolism, Translational Vascular Medicine Branch, National Heart, Lung, and Blood Institute, NIH, Bethesda, Maryland, USA., Ongstad EL; Bioscience Cardiovascular, Research and Early Development, and., Collén A; Projects, Research and Early Development, Cardiovascular, Renal, and Metabolism, BioPharmaceuticals R&D, AstraZeneca, Gaithersburg, Maryland, USA., Playford MP; Section of Inflammation and Cardiometabolic Diseases, Cardiovascular Branch., Eggerman TL; Department of Laboratory Medicine, Clinical Center, NIH, Bethesda, Maryland, USA., Chen MY; Section of Inflammation and Cardiometabolic Diseases, Cardiovascular Branch., Kotani K; Division of Community and Family Medicine, Jichi Medical University, Shimotsuke, Tochigi, Japan., Bocharov AV; Department of Laboratory Medicine, Clinical Center, NIH, Bethesda, Maryland, USA., Remaley AT; Section of Lipoprotein Metabolism, Translational Vascular Medicine Branch, National Heart, Lung, and Blood Institute, NIH, Bethesda, Maryland, USA.

المصدر: JCI insight [JCI Insight] 2023 Oct 23; Vol. 8 (20). Date of Electronic Publication: 2023 Oct 23.

نوع المنشور: Observational Study; Journal Article

بيانات الدورية: Publisher: American Society for Clinical Investigation Country of Publication: United States NLM ID: 101676073 Publication Model: Electronic Cited Medium: Internet ISSN: 2379-3708 (Electronic) Linking ISSN: 23793708 NLM ISO Abbreviation: JCI Insight Subsets: MEDLINE

مواضيع طبية MeSH: Cardiovascular Diseases* , Plaque, Atherosclerotic*/diagnostic imaging, Humans ; Male ; Apolipoprotein A-I ; Apolipoproteins B ; Cholesterol, LDL ; Prospective Studies

المؤلفون: Andersen MK; 1Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Ängquist L; 1Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Bork-Jensen J; 1Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Jonsson AE; 1Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Stinson SE; 1Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Sandholt CH; 1Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Thodberg M; 1Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Pikkupeura LM; 1Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Ongstad EL; 2Research and Early Development, Cardiovascular, Renal and Metabolism, BioPharmaceuticals R&D, AstraZeneca, Gaithersburg, MD., Grarup N; 1Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Astrup A; 3Obesity and Nutrition Science, Novo Nordisk Foundation, Hellerup, Denmark., Pedersen O; 1Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.; 4Center for Clinical Metabolic Research, Gentofte Hospital, Hellerup, Denmark., Williams K; 1Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Barrès R; 1Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Sørensen TIA; 1Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.; 5Department of Public Health, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Linneberg A; 6Centre for Clinical Research and Prevention, Bispebjerg and Frederiksberg Hospital, Copenhagen, Denmark.; 7Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Grimsby J; 2Research and Early Development, Cardiovascular, Renal and Metabolism, BioPharmaceuticals R&D, AstraZeneca, Gaithersburg, MD.; 8Regeneron Pharmaceuticals, Tarrytown, NY., Rhodes CJ; 2Research and Early Development, Cardiovascular, Renal and Metabolism, BioPharmaceuticals R&D, AstraZeneca, Gaithersburg, MD., Hansen T; 1Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.; 9Faculty of Health Sciences, University of Southern Denmark, Odense, Denmark.

المصدر: Diabetes care [Diabetes Care] 2023 May 01; Vol. 46 (5), pp. 985-992.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: American Diabetes Association Country of Publication: United States NLM ID: 7805975 Publication Model: Print Cited Medium: Internet ISSN: 1935-5548 (Electronic) Linking ISSN: 01495992 NLM ISO Abbreviation: Diabetes Care Subsets: MEDLINE

مواضيع طبية MeSH: Insulin Resistance*/genetics , Hyperinsulinism* , Cardiovascular Diseases*, Male ; Humans ; Body Mass Index ; Obesity/genetics ; Obesity/metabolism ; Exercise ; Genetic Predisposition to Disease ; Insulin/genetics ; Insulin, Regular, Human ; Polymorphism, Single Nucleotide ; Genotype ; Alpha-Ketoglutarate-Dependent Dioxygenase FTO/genetics

المؤلفون: Vavere AL; Early Clinical Development, Research and Early Development, Cardiovascular, Renal and Metabolism BioPharmaceuticals R&D, AstraZeneca Gaithersburg MD USA., Sinsakul M; Early Clinical Development, Research and Early Development, Cardiovascular, Renal and Metabolism BioPharmaceuticals R&D, AstraZeneca Gaithersburg MD USA., Ongstad EL; Bioscience Cardiovascular, Research and Early Development, Cardiovascular, Renal and Metabolism BioPharmaceuticals R&D, AstraZeneca Gaithersburg MD USA., Yang Y; Early CVRM Biometrics, Research and Early Development, Cardiovascular, Renal and Metabolism BioPharmaceuticals R&D, AstraZeneca Gaithersburg MD USA., Varma V; Early Clinical Development, Research and Early Development, Cardiovascular, Renal and Metabolism BioPharmaceuticals R&D, AstraZeneca Gaithersburg MD USA., Jones C; Clinical Pharmacology & Quantitative Pharmacology Clinical Pharmacology & Safety Sciences, R&D, AstraZeneca Gothenburg Sweden., Goodman J; Clinical Pharmacology & Quantitative Pharmacology Clinical Pharmacology & Safety Sciences, R&D, AstraZeneca Gothenburg Sweden., Dubois VFS; Clinical Pharmacology & Quantitative Pharmacology Clinical Pharmacology & Safety Sciences, R&D, AstraZeneca Gothenburg Sweden., Quartino AL; Clinical Pharmacology & Quantitative Pharmacology Clinical Pharmacology & Safety Sciences, R&D, AstraZeneca Gothenburg Sweden., Karathanasis SK; Bioscience Cardiovascular, Research and Early Development, Cardiovascular, Renal and Metabolism BioPharmaceuticals R&D, AstraZeneca Gaithersburg MD USA., Abuhatzira L; Early Clinical Development, Research and Early Development, Cardiovascular, Renal and Metabolism BioPharmaceuticals R&D, AstraZeneca Gaithersburg MD USA., Collén A; Projects, Research and Early Development, Cardiovascular, Renal and Metabolism BioPharmaceuticals R&D, AstraZeneca Gothenburg Sweden., Antoniades C; Division of Cardiovascular Medicine, Radcliffe Department of Medicine University of Oxford United Kingdom., Koren MJ; Jacksonville Center for Clinical Research (JCCR) Jacksonville FL USA., Gupta R; Bioscience Cardiovascular, Research and Early Development, Cardiovascular, Renal and Metabolism BioPharmaceuticals R&D, AstraZeneca Gaithersburg MD USA., George RT; Early Clinical Development, Research and Early Development, Cardiovascular, Renal and Metabolism BioPharmaceuticals R&D, AstraZeneca Gaithersburg MD USA.

المصدر: Journal of the American Heart Association [J Am Heart Assoc] 2023 Feb 07; Vol. 12 (3), pp. e027540. Date of Electronic Publication: 2023 Jan 23.

نوع المنشور: Randomized Controlled Trial; Clinical Trial, Phase I; Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Wiley-Blackwell Country of Publication: England NLM ID: 101580524 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2047-9980 (Electronic) Linking ISSN: 20479980 NLM ISO Abbreviation: J Am Heart Assoc Subsets: MEDLINE

مواضيع طبية MeSH: Diabetes Mellitus, Type 2*/diagnosis , Diabetes Mellitus, Type 2*/drug therapy, Humans ; Female ; Middle Aged ; Male ; Antibodies, Monoclonal/therapeutic use ; Lectins/therapeutic use ; Double-Blind Method ; Dose-Response Relationship, Drug

المؤلفون: Stinson SE; Novo Nordisk Foundation Center for Basic Metabolic Research Faculty of Health and Medical Sciences, University of Copenhagen Denmark., Jonsson AE; Novo Nordisk Foundation Center for Basic Metabolic Research Faculty of Health and Medical Sciences, University of Copenhagen Denmark., Andersen MK; Novo Nordisk Foundation Center for Basic Metabolic Research Faculty of Health and Medical Sciences, University of Copenhagen Denmark., Lund MAV; The Children's Obesity Clinic, Accredited European Centre for Obesity Management, Department of Pediatrics Holbæk Hospital Holbæk Denmark.; Department of Biomedical Sciences, Faculty of Health and Medical Sciences University of Copenhagen Denmark., Holm LA; Novo Nordisk Foundation Center for Basic Metabolic Research Faculty of Health and Medical Sciences, University of Copenhagen Denmark.; The Children's Obesity Clinic, Accredited European Centre for Obesity Management, Department of Pediatrics Holbæk Hospital Holbæk Denmark., Fonvig CE; Novo Nordisk Foundation Center for Basic Metabolic Research Faculty of Health and Medical Sciences, University of Copenhagen Denmark.; The Children's Obesity Clinic, Accredited European Centre for Obesity Management, Department of Pediatrics Holbæk Hospital Holbæk Denmark.; Department of Pediatrics Kolding Hospital a part of Lillebælt Hospital Kolding Denmark., Huang Y; Novo Nordisk Foundation Center for Basic Metabolic Research Faculty of Health and Medical Sciences, University of Copenhagen Denmark., Stankevič E; Novo Nordisk Foundation Center for Basic Metabolic Research Faculty of Health and Medical Sciences, University of Copenhagen Denmark., Juel HB; Novo Nordisk Foundation Center for Basic Metabolic Research Faculty of Health and Medical Sciences, University of Copenhagen Denmark., Ängquist L; Novo Nordisk Foundation Center for Basic Metabolic Research Faculty of Health and Medical Sciences, University of Copenhagen Denmark., Sørensen TIA; Novo Nordisk Foundation Center for Basic Metabolic Research Faculty of Health and Medical Sciences, University of Copenhagen Denmark.; Department of Public Health, Faculty of Health and Medical Sciences University of Copenhagen Denmark., Ongstad EL; Research and Early Development Cardiovascular, Renal and Metabolism, BioPharmaceuticals R&D, AstraZeneca Gaithersburg MD., Gaddipati R; Research and Early Development Cardiovascular, Renal and Metabolism, BioPharmaceuticals R&D, AstraZeneca Gaithersburg MD., Grimsby J; Research and Early Development Cardiovascular, Renal and Metabolism, BioPharmaceuticals R&D, AstraZeneca Gaithersburg MD.; Regeneron Pharmaceuticals, Inc. Tarrytown NY., Rhodes CJ; Research and Early Development Cardiovascular, Renal and Metabolism, BioPharmaceuticals R&D, AstraZeneca Gaithersburg MD., Pedersen O; Novo Nordisk Foundation Center for Basic Metabolic Research Faculty of Health and Medical Sciences, University of Copenhagen Denmark., Christiansen M; The Children's Obesity Clinic, Accredited European Centre for Obesity Management, Department of Pediatrics Holbæk Hospital Holbæk Denmark.; Department for Congenital Disorders Statens Serum Institute Copenhagen Denmark., Holm JC; Novo Nordisk Foundation Center for Basic Metabolic Research Faculty of Health and Medical Sciences, University of Copenhagen Denmark.; The Children's Obesity Clinic, Accredited European Centre for Obesity Management, Department of Pediatrics Holbæk Hospital Holbæk Denmark.; Faculty of Health and Medical Sciences University of Copenhagen Denmark., Hansen T; Novo Nordisk Foundation Center for Basic Metabolic Research Faculty of Health and Medical Sciences, University of Copenhagen Denmark.

المصدر: Journal of the American Heart Association [J Am Heart Assoc] 2023 Feb 07; Vol. 12 (3), pp. e8145. Date of Electronic Publication: 2023 Jan 25.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Wiley-Blackwell Country of Publication: England NLM ID: 101580524 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2047-9980 (Electronic) Linking ISSN: 20479980 NLM ISO Abbreviation: J Am Heart Assoc Subsets: MEDLINE

مواضيع طبية MeSH: Cardiovascular Diseases* , Diabetes Mellitus, Type 2* , Pediatric Obesity*/diagnosis , Pediatric Obesity*/epidemiology , Scavenger Receptors, Class E*/blood, Adolescent ; Child ; Humans ; Alanine Transaminase ; Biomarkers ; Cholesterol ; Cross-Sectional Studies ; Inflammation/epidemiology ; Lipoproteins, LDL ; Overweight/epidemiology

المؤلفون: George RT; Early Clinical Development Research and Early Development Cardiovascular, Renal and Metabolism BioPharmaceuticals R&D AstraZeneca Gaithersburg MD., Abuhatzira L; Early Clinical Development Research and Early Development Cardiovascular, Renal and Metabolism BioPharmaceuticals R&D AstraZeneca Gaithersburg MD., Stoughton SM; Early Clinical Development Research and Early Development Cardiovascular, Renal and Metabolism BioPharmaceuticals R&D AstraZeneca Gaithersburg MD., Karathanasis SK; Bioscience Research and Early Development Cardiovascular, Renal and Metabolism BioPharmaceuticals R&D AstraZeneca Gaithersburg MD., She D; Early CVRM Biometrics Research and Early Development Cardiovascular, Renal and Metabolism BioPharmaceuticals R&D AstraZeneca Gaithersburg MD., Jin C; Integrated Bioanalysis Clinical Pharmacology and Quantitative Pharmacology Clinical Pharmacology & Safety Sciences R&D AstraZeneca South San Francisco CA., Buss NAPS; Cardiovascular, Renal and Metabolism Safety Clinical Pharmacology & Safety Sciences R&D AstraZeneca Gaithersburg MD., Bakker-Arkema R; Tanglewood Clinical Consulting Ann Arbor MI., Ongstad EL; Bioscience Research and Early Development Cardiovascular, Renal and Metabolism BioPharmaceuticals R&D AstraZeneca Gaithersburg MD., Koren M; Jacksonville Center for Clinical Research Jacksonville FL., Hirshberg B; Early Clinical Development Research and Early Development Cardiovascular, Renal and Metabolism BioPharmaceuticals R&D AstraZeneca Gaithersburg MD.

المصدر: Journal of the American Heart Association [J Am Heart Assoc] 2021 Jul 06; Vol. 10 (13), pp. e014572. Date of Electronic Publication: 2021 Jun 14.

نوع المنشور: Clinical Trial, Phase II; Journal Article; Multicenter Study; Randomized Controlled Trial; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Wiley-Blackwell Country of Publication: England NLM ID: 101580524 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2047-9980 (Electronic) Linking ISSN: 20479980 NLM ISO Abbreviation: J Am Heart Assoc Subsets: MEDLINE

مواضيع طبية MeSH: Coronary Disease/*drug therapy , Lipoproteins, HDL/*administration & dosage , Lipoproteins, LDL/*administration & dosage , Phosphatidylcholine-Sterol O-Acyltransferase/*administration & dosage , Recombinant Proteins/*administration & dosage, Administration, Intravenous ; Adult ; Aged ; Apolipoprotein A-I/blood ; Dose-Response Relationship, Drug ; Double-Blind Method ; Female ; Humans ; Injections, Subcutaneous ; Lipoproteins, HDL/adverse effects ; Lipoproteins, HDL/blood ; Lipoproteins, LDL/adverse effects ; Lipoproteins, LDL/blood ; Male ; Middle Aged ; Phosphatidylcholine-Sterol O-Acyltransferase/adverse effects ; Phosphatidylcholine-Sterol O-Acyltransferase/blood ; Recombinant Proteins/adverse effects ; Recombinant Proteins/blood ; Treatment Outcome

المؤلفون: Sagar D; Respiratory, Inflammation and Autoimmune, Biopharmaceuticals R&D, AstraZeneca, Gaithersburg, Maryland, United States of America., Gaddipati R; Cardiovascular, Renal and Metabolism, Biopharmaceuticals R&D, AstraZeneca, Gaithersburg, Maryland, United States of America., Ongstad EL; Cardiovascular, Renal and Metabolism, Biopharmaceuticals R&D, AstraZeneca, Gaithersburg, Maryland, United States of America., Bhagroo N; Cardiovascular, Renal and Metabolism, Biopharmaceuticals R&D, AstraZeneca, Gaithersburg, Maryland, United States of America., An LL; Respiratory, Inflammation and Autoimmune, Biopharmaceuticals R&D, AstraZeneca, Gaithersburg, Maryland, United States of America., Wang J; Respiratory, Inflammation and Autoimmune, Biopharmaceuticals R&D, AstraZeneca, Gaithersburg, Maryland, United States of America., Belkhodja M; Cardiovascular, Renal and Metabolism, Biopharmaceuticals R&D, AstraZeneca, Gaithersburg, Maryland, United States of America., Rahman S; Respiratory, Inflammation and Autoimmune, Biopharmaceuticals R&D, AstraZeneca, Gaithersburg, Maryland, United States of America., Manna Z; National Institute of Arthritis and Musculoskeletal and Skin Diseases, National Institute of Health, Bethesda, Maryland, United States of America., Davis MA; National Institute of Arthritis and Musculoskeletal and Skin Diseases, National Institute of Health, Bethesda, Maryland, United States of America., Hasni S; National Institute of Arthritis and Musculoskeletal and Skin Diseases, National Institute of Health, Bethesda, Maryland, United States of America., Siegel R; National Institute of Arthritis and Musculoskeletal and Skin Diseases, National Institute of Health, Bethesda, Maryland, United States of America., Sanjuan M; Respiratory, Inflammation and Autoimmune, Biopharmaceuticals R&D, AstraZeneca, Gaithersburg, Maryland, United States of America., Grimsby J; Cardiovascular, Renal and Metabolism, Biopharmaceuticals R&D, AstraZeneca, Gaithersburg, Maryland, United States of America., Kolbeck R; Respiratory, Inflammation and Autoimmune, Biopharmaceuticals R&D, AstraZeneca, Gaithersburg, Maryland, United States of America., Karathanasis S; Cardiovascular, Renal and Metabolism, Biopharmaceuticals R&D, AstraZeneca, Gaithersburg, Maryland, United States of America., Sims GP; Respiratory, Inflammation and Autoimmune, Biopharmaceuticals R&D, AstraZeneca, Gaithersburg, Maryland, United States of America., Gupta R; Cardiovascular, Renal and Metabolism, Biopharmaceuticals R&D, AstraZeneca, Gaithersburg, Maryland, United States of America.

المصدر: PloS one [PLoS One] 2020 Mar 17; Vol. 15 (3), pp. e0229184. Date of Electronic Publication: 2020 Mar 17 (Print Publication: 2020).

نوع المنشور: Journal Article; Research Support, N.I.H., Intramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet ISSN: 1932-6203 (Electronic) Linking ISSN: 19326203 NLM ISO Abbreviation: PLoS One Subsets: MEDLINE

مواضيع طبية MeSH: Cardiovascular Diseases/*etiology , Lupus Erythematosus, Systemic/*blood , Lupus Erythematosus, Systemic/*complications , Scavenger Receptors, Class E/*physiology, Adult ; Atherosclerosis/blood ; Atherosclerosis/complications ; Cardiovascular Diseases/blood ; Case-Control Studies ; Disease Progression ; Female ; Humans ; Inflammation/blood ; Inflammation/complications ; Lupus Erythematosus, Systemic/pathology ; Male ; Middle Aged ; Risk Factors ; Scavenger Receptors, Class E/blood ; Young Adult

المؤلفون: Marchetti GM; Antibody Discovery & Protein Engineering, MedImmune, Gaithersburg, MD, 20878, USA.; Cardiovascular & Metabolic Diseases, MedImmune, Gaithersburg, MD, 20878, USA., Burwell TJ; Respiratory, Inflammation and Autoimmune Diseases, MedImmune, Gaithersburg, MD, 20878, USA., Peterson NC; Translational Sciences, MedImmune, Gaithersburg, MD, 20878, USA., Cann JA; Pathology, MedImmune, Gaithersburg, MD, 20878, USA., Hanna RN; Respiratory, Inflammation and Autoimmune Diseases, MedImmune, Gaithersburg, MD, 20878, USA., Li Q; Antibody Discovery & Protein Engineering, MedImmune, Gaithersburg, MD, 20878, USA., Ongstad EL; Cardiovascular & Metabolic Diseases, MedImmune, Gaithersburg, MD, 20878, USA., Boyd JT; Microbial Sciences, MedImmune, Gaithersburg, MD, 20878, USA., Kennedy MA; Pathology, MedImmune, Gaithersburg, MD, 20878, USA., Zhao W; Pathology, MedImmune, Gaithersburg, MD, 20878, USA., Rickert KW; Antibody Discovery & Protein Engineering, MedImmune, Gaithersburg, MD, 20878, USA., Grimsby JS; Cardiovascular & Metabolic Diseases, MedImmune, Gaithersburg, MD, 20878, USA., Dall'Acqua WF; Antibody Discovery & Protein Engineering, MedImmune, Gaithersburg, MD, 20878, USA., Wu H; Antibody Discovery & Protein Engineering, MedImmune, Gaithersburg, MD, 20878, USA., Tsui P; Antibody Discovery & Protein Engineering, MedImmune, Gaithersburg, MD, 20878, USA., Borrok MJ; Antibody Discovery & Protein Engineering, MedImmune, Gaithersburg, MD, 20878, USA. borrokm@medimmune.com., Gupta R; Cardiovascular & Metabolic Diseases, MedImmune, Gaithersburg, MD, 20878, USA.

المصدر: Communications biology [Commun Biol] 2019 Mar 07; Vol. 2, pp. 92. Date of Electronic Publication: 2019 Mar 07 (Print Publication: 2019).

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Nature Publishing Group UK Country of Publication: England NLM ID: 101719179 Publication Model: eCollection Cited Medium: Internet ISSN: 2399-3642 (Electronic) Linking ISSN: 23993642 NLM ISO Abbreviation: Commun Biol

مواضيع طبية MeSH: Drug Carriers* , Drug Delivery Systems*, Idiopathic Pulmonary Fibrosis/*drug therapy , Membrane Proteins/*metabolism, Animals ; Biomarkers ; Bleomycin/adverse effects ; Dinoprostone/metabolism ; Disease Models, Animal ; Gene Expression ; Humans ; Idiopathic Pulmonary Fibrosis/etiology ; Idiopathic Pulmonary Fibrosis/pathology ; Immunohistochemistry ; Kidney/metabolism ; Kidney/pathology ; Lung/drug effects ; Lung/metabolism ; Lung/pathology ; Membrane Proteins/chemistry ; Membrane Proteins/genetics ; Mice