المؤلفون: Whiterock VJ; Department of Metabolism and Pharmacokinetics, Bristol-Myers Squibb Company, Wallingford, Connecticut, USA. valerie.whiterock@bms.com, Morgan DG, Lentz KA, Orcutt TL, Sinz MW

المصدر: Drug metabolism and disposition: the biological fate of chemicals [Drug Metab Dispos] 2012 Feb; Vol. 40 (2), pp. 228-31. Date of Electronic Publication: 2011 Nov 10.

نوع المنشور: Comparative Study; Journal Article

بيانات الدورية: Publisher: American Society for Pharmacology and Experimental Therapeutics, etc.] Country of Publication: United States NLM ID: 9421550 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1521-009X (Electronic) Linking ISSN: 00909556 NLM ISO Abbreviation: Drug Metab Dispos Subsets: MEDLINE

مواضيع طبية MeSH: Analgesics, Non-Narcotic/*pharmacokinetics , Cytochrome P-450 CYP1A2/*metabolism , Phenacetin/*pharmacokinetics, Acetaminophen/blood ; Administration, Oral ; Algorithms ; Analgesics, Non-Narcotic/administration & dosage ; Analgesics, Non-Narcotic/blood ; Animals ; Biotransformation ; Codon, Terminator ; Cytochrome P-450 CYP1A2/deficiency ; Cytochrome P-450 CYP1A2/genetics ; Dogs ; Dose-Response Relationship, Drug ; Half-Life ; Heterozygote ; Homozygote ; Infusions, Intravenous ; Male ; Metabolic Clearance Rate ; Mutation ; Phenacetin/administration & dosage ; Phenacetin/blood ; Polymorphism, Single Nucleotide ; Substrate Specificity

المؤلفون: Whiterock VJ; Department of Metabolism and Pharmacokinetics, Bristol-Myers Squibb Company, Wallingford, CT 06492, USA. valerie.whiterock@bms.com, Delmonte TA, Hui LE, Orcutt TL, Sinz MW

المصدر: Drug metabolism letters [Drug Metab Lett] 2007 Apr; Vol. 1 (2), pp. 163-5.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Bentham Science Publishers Country of Publication: United Arab Emirates NLM ID: 101313587 Publication Model: Print Cited Medium: Internet ISSN: 1874-0758 (Electronic) Linking ISSN: 18723128 NLM ISO Abbreviation: Drug Metab Lett Subsets: MEDLINE

مواضيع طبية MeSH: Gene Frequency* , Polymorphism, Single Nucleotide*, Cytochrome P-450 CYP1A2/*genetics, Animals ; Dogs ; Female ; Heterozygote ; Homozygote ; Male ; Mutation