المؤلفون: Wipperman MF; Regeneron Pharmaceuticals Inc., Tarrytown, New York, USA., Gayvert KM; Regeneron Pharmaceuticals Inc., Tarrytown, New York, USA., Atanasio A; Regeneron Pharmaceuticals Inc., Tarrytown, New York, USA., Wang CQ; Regeneron Pharmaceuticals Inc., Tarrytown, New York, USA., Corren J; Department of Pediatrics, David Geffen School of Medicine, University of California, Los Angeles, California, USA., Covarrubias A; Clinical Research Division, Jonathan Corren, MD. Inc., Los Angeles, California, USA., Setliff I; Regeneron Pharmaceuticals Inc., Tarrytown, New York, USA., Chio E; Regeneron Pharmaceuticals Inc., Tarrytown, New York, USA., Laws E; Sanofi, Bridgewater, New Jersey, USA., Wolfe K; Sanofi, Bridgewater, New Jersey, USA., Harel S; Regeneron Pharmaceuticals Inc., Tarrytown, New York, USA., Maloney J; Regeneron Pharmaceuticals Inc., Tarrytown, New York, USA., Herman G; Regeneron Pharmaceuticals Inc., Tarrytown, New York, USA., Orengo JM; Regeneron Pharmaceuticals Inc., Tarrytown, New York, USA., Lim WK; Regeneron Pharmaceuticals Inc., Tarrytown, New York, USA., Hamon SC; Regeneron Pharmaceuticals Inc., Tarrytown, New York, USA., Hamilton JD; Regeneron Pharmaceuticals Inc., Tarrytown, New York, USA., O'Brien MP; Regeneron Pharmaceuticals Inc., Tarrytown, New York, USA.

المصدر: Allergy [Allergy] 2024 Apr; Vol. 79 (4), pp. 894-907. Date of Electronic Publication: 2024 Jan 27.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Wiley-Blackwell Country of Publication: Denmark NLM ID: 7804028 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1398-9995 (Electronic) Linking ISSN: 01054538 NLM ISO Abbreviation: Allergy Subsets: MEDLINE

مواضيع طبية MeSH: Transcriptome* , Rhinitis, Allergic*/genetics , Rhinitis, Allergic*/therapy , Antibodies, Monoclonal, Humanized*, Humans ; Allergens ; Inflammation ; Phleum ; Interleukin-13/metabolism ; Immunotherapy

المؤلفون: Limnander A; Regeneron Pharmaceuticals, Tarrytown, New York, 10591, USA., Kaur N; Regeneron Pharmaceuticals, Tarrytown, New York, 10591, USA., Asrat S; Regeneron Pharmaceuticals, Tarrytown, New York, 10591, USA., Tasker C; Regeneron Pharmaceuticals, Tarrytown, New York, 10591, USA., Boyapati A; Regeneron Pharmaceuticals, Tarrytown, New York, 10591, USA., Ben LH; Regeneron Pharmaceuticals, Tarrytown, New York, 10591, USA., Janczy J; Regeneron Pharmaceuticals, Tarrytown, New York, 10591, USA., Pedraza P; Regeneron Pharmaceuticals, Tarrytown, New York, 10591, USA., Abreu P; Regeneron Pharmaceuticals, Tarrytown, New York, 10591, USA., Chen WC; Regeneron Pharmaceuticals, Tarrytown, New York, 10591, USA., Godin S; Regeneron Pharmaceuticals, Tarrytown, New York, 10591, USA., Daniel BJ; Regeneron Pharmaceuticals, Tarrytown, New York, 10591, USA., Chin H; Regeneron Pharmaceuticals, Tarrytown, New York, 10591, USA., DeVeaux M; Regeneron Pharmaceuticals, Tarrytown, New York, 10591, USA., Rodriguez Lorenc K; Regeneron Pharmaceuticals, Tarrytown, New York, 10591, USA., Sirulnik A; Regeneron Pharmaceuticals, Tarrytown, New York, 10591, USA., Harari O; Regeneron Pharmaceuticals, Tarrytown, New York, 10591, USA., Stahl N; Regeneron Pharmaceuticals, Tarrytown, New York, 10591, USA., Sleeman MA; Regeneron Pharmaceuticals, Tarrytown, New York, 10591, USA., Murphy AJ; Regeneron Pharmaceuticals, Tarrytown, New York, 10591, USA., Yancopoulos GD; Regeneron Pharmaceuticals, Tarrytown, New York, 10591, USA., Orengo JM; Regeneron Pharmaceuticals, Tarrytown, New York, 10591, USA.

المصدر: Science translational medicine [Sci Transl Med] 2023 Dec 13; Vol. 15 (726), pp. eadf9561. Date of Electronic Publication: 2023 Dec 13.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 101505086 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1946-6242 (Electronic) Linking ISSN: 19466234 NLM ISO Abbreviation: Sci Transl Med Subsets: MEDLINE

مواضيع طبية MeSH: Immunoglobulin E* , Anaphylaxis*, Mice ; Humans ; Animals ; Macaca fascicularis ; Plasma Cells ; Allergens

المؤلفون: Asrat S; Regeneron Pharmaceuticals, Tarrytown, NY 10591, USA., Devlin JC; Regeneron Pharmaceuticals, Tarrytown, NY 10591, USA., Vecchione A; Regeneron Pharmaceuticals, Tarrytown, NY 10591, USA., Klotz B; Regeneron Pharmaceuticals, Tarrytown, NY 10591, USA., Setliff I; Regeneron Pharmaceuticals, Tarrytown, NY 10591, USA., Srivastava D; Regeneron Pharmaceuticals, Tarrytown, NY 10591, USA., Limnander A; Regeneron Pharmaceuticals, Tarrytown, NY 10591, USA., Rafique A; Regeneron Pharmaceuticals, Tarrytown, NY 10591, USA., Adler C; Regeneron Pharmaceuticals, Tarrytown, NY 10591, USA., Porter S; Regeneron Pharmaceuticals, Tarrytown, NY 10591, USA., Murphy AJ; Regeneron Pharmaceuticals, Tarrytown, NY 10591, USA., Atwal GS; Regeneron Pharmaceuticals, Tarrytown, NY 10591, USA., Sleeman MA; Regeneron Pharmaceuticals, Tarrytown, NY 10591, USA., Lim WK; Regeneron Pharmaceuticals, Tarrytown, NY 10591, USA., Orengo JM; Regeneron Pharmaceuticals, Tarrytown, NY 10591, USA.

المصدر: Cell reports methods [Cell Rep Methods] 2023 Jul 07; Vol. 3 (7), pp. 100522. Date of Electronic Publication: 2023 Jul 07 (Print Publication: 2023).

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Elsevier Inc Country of Publication: United States NLM ID: 9918227360606676 Publication Model: eCollection Cited Medium: Internet ISSN: 2667-2375 (Electronic) Linking ISSN: 26672375 NLM ISO Abbreviation: Cell Rep Methods Subsets: MEDLINE

مواضيع طبية MeSH: Antibody-Producing Cells* , Antigens*, Humans ; Animals ; Mice ; B-Lymphocytes ; Antibodies/genetics ; Receptors, Antigen, B-Cell/genetics

المؤلفون: Scott G; Regeneron Pharmaceuticals Inc., 777 Old Saw Mill River Road, Tarrytown, NY 10591, USA., Asrat S; Regeneron Pharmaceuticals Inc., 777 Old Saw Mill River Road, Tarrytown, NY 10591, USA., Allinne J; Regeneron Pharmaceuticals Inc., 777 Old Saw Mill River Road, Tarrytown, NY 10591, USA., Keat Lim W; Regeneron Pharmaceuticals Inc., 777 Old Saw Mill River Road, Tarrytown, NY 10591, USA., Nagashima K; Regeneron Pharmaceuticals Inc., 777 Old Saw Mill River Road, Tarrytown, NY 10591, USA., Birchard D; Regeneron Pharmaceuticals Inc., 777 Old Saw Mill River Road, Tarrytown, NY 10591, USA., Srivatsan S; Regeneron Pharmaceuticals Inc., 777 Old Saw Mill River Road, Tarrytown, NY 10591, USA., Ajithdoss DK; Regeneron Pharmaceuticals Inc., 777 Old Saw Mill River Road, Tarrytown, NY 10591, USA., Oyejide A; Regeneron Pharmaceuticals Inc., 777 Old Saw Mill River Road, Tarrytown, NY 10591, USA., Ben LH; Regeneron Pharmaceuticals Inc., 777 Old Saw Mill River Road, Tarrytown, NY 10591, USA., Walls J; Regeneron Pharmaceuticals Inc., 777 Old Saw Mill River Road, Tarrytown, NY 10591, USA., Le Floc'h A; Regeneron Pharmaceuticals Inc., 777 Old Saw Mill River Road, Tarrytown, NY 10591, USA., Yancopoulos GD; Regeneron Pharmaceuticals Inc., 777 Old Saw Mill River Road, Tarrytown, NY 10591, USA., Murphy AJ; Regeneron Pharmaceuticals Inc., 777 Old Saw Mill River Road, Tarrytown, NY 10591, USA., Sleeman MA; Regeneron Pharmaceuticals Inc., 777 Old Saw Mill River Road, Tarrytown, NY 10591, USA., Orengo JM; Regeneron Pharmaceuticals Inc., 777 Old Saw Mill River Road, Tarrytown, NY 10591, USA. Electronic address: jamie.orengo@regeneron.com.

المصدر: Cytokine [Cytokine] 2023 Feb; Vol. 162, pp. 156091. Date of Electronic Publication: 2022 Dec 05.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Elsevier Science Ltd Country of Publication: England NLM ID: 9005353 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1096-0023 (Electronic) Linking ISSN: 10434666 NLM ISO Abbreviation: Cytokine Subsets: MEDLINE

مواضيع طبية MeSH: Asthma*/metabolism , Pneumonia*/metabolism, Animals ; Humans ; Mice ; Chemokines/metabolism ; Cytokines/metabolism ; Endothelial Cells/metabolism ; Inflammation/metabolism ; Interleukin-13/metabolism ; Lung/metabolism ; Interleukin-4/pharmacology

المؤلفون: Le Floc'h A; Regeneron Pharmaceuticals, 777 Old Saw Mill River Road, Tarrytown, NY 10591, USA., Nagashima K; Regeneron Pharmaceuticals, 777 Old Saw Mill River Road, Tarrytown, NY 10591, USA., Birchard D; Regeneron Pharmaceuticals, 777 Old Saw Mill River Road, Tarrytown, NY 10591, USA., Scott G; Regeneron Pharmaceuticals, 777 Old Saw Mill River Road, Tarrytown, NY 10591, USA., Ben LH; Regeneron Pharmaceuticals, 777 Old Saw Mill River Road, Tarrytown, NY 10591, USA., Ajithdoss D; Regeneron Pharmaceuticals, 777 Old Saw Mill River Road, Tarrytown, NY 10591, USA., Gayvert K; Regeneron Pharmaceuticals, 777 Old Saw Mill River Road, Tarrytown, NY 10591, USA., Romero Hernandez A; Regeneron Pharmaceuticals, 777 Old Saw Mill River Road, Tarrytown, NY 10591, USA., Herbin O; Regeneron Pharmaceuticals, 777 Old Saw Mill River Road, Tarrytown, NY 10591, USA., Tay A; Regeneron Pharmaceuticals, 777 Old Saw Mill River Road, Tarrytown, NY 10591, USA., Farrales P; Regeneron Pharmaceuticals, 777 Old Saw Mill River Road, Tarrytown, NY 10591, USA., Korgaonkar CK; Regeneron Pharmaceuticals, 777 Old Saw Mill River Road, Tarrytown, NY 10591, USA., Pan H; Regeneron Pharmaceuticals, 777 Old Saw Mill River Road, Tarrytown, NY 10591, USA., Shah S; Regeneron Pharmaceuticals, 777 Old Saw Mill River Road, Tarrytown, NY 10591, USA., Kamat V; Regeneron Pharmaceuticals, 777 Old Saw Mill River Road, Tarrytown, NY 10591, USA., Chatterjee I; Regeneron Pharmaceuticals, 777 Old Saw Mill River Road, Tarrytown, NY 10591, USA., Popke J; Regeneron Pharmaceuticals, 777 Old Saw Mill River Road, Tarrytown, NY 10591, USA., Oyejide A; Regeneron Pharmaceuticals, 777 Old Saw Mill River Road, Tarrytown, NY 10591, USA., Lim WK; Regeneron Pharmaceuticals, 777 Old Saw Mill River Road, Tarrytown, NY 10591, USA., Kim JH; Regeneron Pharmaceuticals, 777 Old Saw Mill River Road, Tarrytown, NY 10591, USA., Huang T; Regeneron Pharmaceuticals, 777 Old Saw Mill River Road, Tarrytown, NY 10591, USA., Franklin M; Regeneron Pharmaceuticals, 777 Old Saw Mill River Road, Tarrytown, NY 10591, USA., Olson W; Regeneron Pharmaceuticals, 777 Old Saw Mill River Road, Tarrytown, NY 10591, USA., Norton T; Regeneron Pharmaceuticals, 777 Old Saw Mill River Road, Tarrytown, NY 10591, USA., Perlee L; Regeneron Pharmaceuticals, 777 Old Saw Mill River Road, Tarrytown, NY 10591, USA., Yancopoulos GD; Regeneron Pharmaceuticals, 777 Old Saw Mill River Road, Tarrytown, NY 10591, USA., Murphy AJ; Regeneron Pharmaceuticals, 777 Old Saw Mill River Road, Tarrytown, NY 10591, USA., Sleeman MA; Regeneron Pharmaceuticals, 777 Old Saw Mill River Road, Tarrytown, NY 10591, USA., Orengo JM; Regeneron Pharmaceuticals, 777 Old Saw Mill River Road, Tarrytown, NY 10591, USA.

المصدر: Science translational medicine [Sci Transl Med] 2023 Jan 11; Vol. 15 (678), pp. eabo0205. Date of Electronic Publication: 2023 Jan 11.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 101505086 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1946-6242 (Electronic) Linking ISSN: 19466234 NLM ISO Abbreviation: Sci Transl Med Subsets: MEDLINE

مواضيع طبية MeSH: Anemia, Aplastic*/metabolism , Graft vs Host Disease*/metabolism , T-Lymphocytes*/metabolism , T-Lymphocytes*/pathology , Interleukin Receptor Common gamma Subunit*/antagonists & inhibitors , Interleukin Receptor Common gamma Subunit*/metabolism, Animals ; Mice ; Antibodies, Monoclonal/metabolism ; Cytokines/metabolism ; Signal Transduction ; Primates

المؤلفون: de Blay FJ; ALYATEC Environmental Exposure Chamber, Strasbourg, France; Chest Diseases Department, Strasbourg University Hospital, Strasbourg, France; Federation of Translational Medicine EA 3070, University of Strasbourg, Strasbourg, France., Gherasim A; ALYATEC Environmental Exposure Chamber, Strasbourg, France., Domis N; ALYATEC Environmental Exposure Chamber, Strasbourg, France., Meier P; Regeneron Pharmaceuticals Inc, Tarrytown, NY., Shawki F; Regeneron Pharmaceuticals Inc, Tarrytown, NY., Wang CQ; Regeneron Pharmaceuticals Inc, Tarrytown, NY., Orengo JM; Regeneron Pharmaceuticals Inc, Tarrytown, NY., DeVeaux M; Regeneron Pharmaceuticals Inc, Tarrytown, NY., Ramesh D; Regeneron Pharmaceuticals Inc, Tarrytown, NY., Jalbert JJ; Regeneron Pharmaceuticals Inc, Tarrytown, NY., Kamal MA; Regeneron Pharmaceuticals Inc, Tarrytown, NY., Abdallah H; Regeneron Pharmaceuticals Inc, Tarrytown, NY., Dingman R; Regeneron Pharmaceuticals Inc, Tarrytown, NY., Perlee L; Regeneron Pharmaceuticals Inc, Tarrytown, NY., Weinreich DM; Regeneron Pharmaceuticals Inc, Tarrytown, NY., Herman G; Regeneron Pharmaceuticals Inc, Tarrytown, NY., Yancopoulos GD; Regeneron Pharmaceuticals Inc, Tarrytown, NY., O'Brien MP; Regeneron Pharmaceuticals Inc, Tarrytown, NY. Electronic address: meagan.obrien@regeneron.com.

المصدر: The Journal of allergy and clinical immunology [J Allergy Clin Immunol] 2022 Dec; Vol. 150 (6), pp. 1437-1446. Date of Electronic Publication: 2022 Aug 04.

نوع المنشور: Randomized Controlled Trial; Journal Article

بيانات الدورية: Publisher: Mosby Country of Publication: United States NLM ID: 1275002 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1097-6825 (Electronic) Linking ISSN: 00916749 NLM ISO Abbreviation: J Allergy Clin Immunol Subsets: MEDLINE

مواضيع طبية MeSH: Allergens* , Health Status*, Environmental Exposure/adverse effects

المؤلفون: Atanasio A; Immunology and Inflammation, Regeneron Pharmaceuticals, Inc., Tarrytown, NY, United States., Orengo JM; Immunology and Inflammation, Regeneron Pharmaceuticals, Inc., Tarrytown, NY, United States., Sleeman MA; Immunology and Inflammation, Regeneron Pharmaceuticals, Inc., Tarrytown, NY, United States., Stahl N; Research and Development, Regeneron Pharmaceuticals, Inc., Tarrytown, NY, United States.

المصدر: Frontiers in allergy [Front Allergy] 2022 Oct 24; Vol. 3, pp. 1019255. Date of Electronic Publication: 2022 Oct 24 (Print Publication: 2022).

نوع المنشور: Journal Article; Review

بيانات الدورية: Publisher: Frontiers Media S.A Country of Publication: Switzerland NLM ID: 9918227355906676 Publication Model: eCollection Cited Medium: Internet ISSN: 2673-6101 (Electronic) Linking ISSN: 26736101 NLM ISO Abbreviation: Front Allergy Subsets: PubMed not MEDLINE

المؤلفون: Erjefält JS; Unit of Airway inflammation, Department of Experimental Medicine Sciences, Lund University, Sweden; Department of Allergology and Respiratory Medicine, Lund University, Sweden., de Souza Xavier Costa N; Departamento de Patologia, LIM-05 Laboratório de Patologia Ambiental, Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil., Jönsson J; Medetect AB, Lund, Sweden., Cozzolino O; Unit of Airway inflammation, Department of Experimental Medicine Sciences, Lund University, Sweden., Dantas KC; Departamento de Patologia, LIM-05 Laboratório de Patologia Ambiental, Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil., Clausson CM; Unit of Airway inflammation, Department of Experimental Medicine Sciences, Lund University, Sweden., Siddhuraj P; Unit of Airway inflammation, Department of Experimental Medicine Sciences, Lund University, Sweden., Lindö C; Medetect AB, Lund, Sweden., Alyamani M; Unit of Airway inflammation, Department of Experimental Medicine Sciences, Lund University, Sweden., Lombardi SCFS; Divisão de Pesquisa & Medicina Transfusional, Fundação Pró-Sangue Hemocentro de São Paulo, São Paulo, Brazil; Laboratório Investigação Médica em Patogênese e Terapia dirigida em Onco-Imuno-Hematologia (LIM-31), Departamento de Hematologia, Hospital das Clínicas HCFMUSP, Faculdade de Medicina, Universidade de São Paulo, São Paulo, Brazil., Mendroni Júnior A; Divisão de Pesquisa & Medicina Transfusional, Fundação Pró-Sangue Hemocentro de São Paulo, São Paulo, Brazil; Laboratório Investigação Médica em Patogênese e Terapia dirigida em Onco-Imuno-Hematologia (LIM-31), Departamento de Hematologia, Hospital das Clínicas HCFMUSP, Faculdade de Medicina, Universidade de São Paulo, São Paulo, Brazil., Antonangelo L; Laboratório de Investigação Médica (LIM03), Hospital das Clínicas HCFMUSP, Faculdade de Medicina, Universidade de São Paulo, São Paulo, Brazil; Divisão de Patologia Clínica - Departamento de Patologia, Hospital das Clínicas HCFMUSP, Faculdade de Medicina, Universidade de São Paulo, São Paulo, Brazil., Faria CS; Laboratório de Investigação Médica (LIM03), Hospital das Clínicas HCFMUSP, Faculdade de Medicina, Universidade de São Paulo, São Paulo, Brazil., Duarte-Neto AN; Departamento de Patologia, LIM-05 Laboratório de Patologia Ambiental, Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil., de Almeida Monteiro RA; Departamento de Patologia, LIM-05 Laboratório de Patologia Ambiental, Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil., Rebello Pinho JR; Laboratório de Investigação Médica (LIM03), Hospital das Clínicas HCFMUSP, Faculdade de Medicina, Universidade de São Paulo, São Paulo, Brazil; Hospital Israelita Albert Einstein, São Paulo, Brazil., Gomes-Gouvêa MS; Departamento de Gastroenterologia (LIM-07), Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil., Verciano Pereira R; Laboratório de Investigação Médica (LIM03), Hospital das Clínicas HCFMUSP, Faculdade de Medicina, Universidade de São Paulo, São Paulo, Brazil., Monteiro JS; Departamento de Bioquímica, Instituto de Química Universidade de São Paulo, São Paulo, Brazil., Setubal JC; Departamento de Bioquímica, Instituto de Química Universidade de São Paulo, São Paulo, Brazil., de Oliveira EP; Departamento de Cardiopneumologia, Instituto do Coração, Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil., Theodoro Filho J; Departamento de Patologia, LIM-05 Laboratório de Patologia Ambiental, Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil., Sanden C; Medetect AB, Lund, Sweden., Orengo JM; Regeneron Pharmaceuticals, Tarrytown, NY, USA., Sleeman MA; Regeneron Pharmaceuticals, Tarrytown, NY, USA., da Silva LFF; Departamento de Patologia, LIM-05 Laboratório de Patologia Ambiental, Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil; Serviço de Verificação de Óbitos da Capital, Universidade de São Paulo, São Paulo, Brazil., Saldiva PHN; Departamento de Patologia, LIM-05 Laboratório de Patologia Ambiental, Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil., Dolhnikoff M; Departamento de Patologia, LIM-05 Laboratório de Patologia Ambiental, Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil., Mauad T; Departamento de Patologia, LIM-05 Laboratório de Patologia Ambiental, Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil. Electronic address: tmauad@usp.br.

المصدر: EBioMedicine [EBioMedicine] 2022 Sep; Vol. 83, pp. 104229. Date of Electronic Publication: 2022 Aug 24.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Elsevier B.V Country of Publication: Netherlands NLM ID: 101647039 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2352-3964 (Electronic) Linking ISSN: 23523964 NLM ISO Abbreviation: EBioMedicine Subsets: MEDLINE

مواضيع طبية MeSH: COVID-19*, Cytokines ; Humans ; Lung/pathology ; SARS-CoV-2

المؤلفون: Gevaert P; Department of Otorhinolaryngology, Ghent University Hospital, Ghent, Belgium., De Craemer J; Department of Otorhinolaryngology, Ghent University Hospital, Ghent, Belgium., De Ruyck N; Department of Otorhinolaryngology, Ghent University Hospital, Ghent, Belgium., Rottey S; Drug Research Unit Ghent, Ghent University Hospital, Ghent, Belgium., de Hoon J; Center for Clinical Pharmacology, UZ Leuven, Leuven, Belgium., Hellings PW; Department of Otorhinolaryngology, Ghent University Hospital, Ghent, Belgium; Allergy and Clinical Immunology Research Group, KU Leuven, Leuven, Belgium; Academic Medical Center Amsterdam, University of Amsterdam, Amsterdam, The Netherlands., Volckaert B; SGS Belgium Clinical Pharmacology Unit Antwerpen, Antwerp, Belgium., Lesneuck K; SGS Belgium Clinical Pharmacology Unit Antwerpen, Antwerp, Belgium., Orengo JM; Regeneron Pharmaceuticals, Inc, Tarrytown, NY., Atanasio A; Regeneron Pharmaceuticals, Inc, Tarrytown, NY., Kamal MA; Regeneron Pharmaceuticals, Inc, Tarrytown, NY., Abdallah H; Regeneron Pharmaceuticals, Inc, Tarrytown, NY., Kamat V; Regeneron Pharmaceuticals, Inc, Tarrytown, NY., Dingman R; Regeneron Pharmaceuticals, Inc, Tarrytown, NY., DeVeaux M; Regeneron Pharmaceuticals, Inc, Tarrytown, NY., Ramesh D; Regeneron Pharmaceuticals, Inc, Tarrytown, NY., Perlee L; Regeneron Pharmaceuticals, Inc, Tarrytown, NY., Wang CQ; Regeneron Pharmaceuticals, Inc, Tarrytown, NY., Weinreich DM; Regeneron Pharmaceuticals, Inc, Tarrytown, NY., Herman G; Regeneron Pharmaceuticals, Inc, Tarrytown, NY., Yancopoulos GD; Regeneron Pharmaceuticals, Inc, Tarrytown, NY., O'Brien MP; Regeneron Pharmaceuticals, Inc, Tarrytown, NY. Electronic address: meagan.obrien@regeneron.com.

المصدر: The Journal of allergy and clinical immunology [J Allergy Clin Immunol] 2022 Jan; Vol. 149 (1), pp. 189-199. Date of Electronic Publication: 2021 Jun 11.

نوع المنشور: Clinical Trial, Phase I; Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Mosby Country of Publication: United States NLM ID: 1275002 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1097-6825 (Electronic) Linking ISSN: 00916749 NLM ISO Abbreviation: J Allergy Clin Immunol Subsets: MEDLINE

مواضيع طبية MeSH: Allergens/*immunology , Antibodies, Monoclonal/*therapeutic use , Antigens, Plant/*immunology , Immunoglobulin G/*therapeutic use , Rhinitis, Allergic, Seasonal/*therapy, Adult ; Basophils/immunology ; Betula/immunology ; Desensitization, Immunologic ; Double-Blind Method ; Female ; Humans ; Male ; Middle Aged ; Rhinitis, Allergic, Seasonal/immunology ; Young Adult

المؤلفون: Atanasio A; Regeneron Pharmaceuticals, Inc, Tarrytown, NY., Franklin MC; Regeneron Pharmaceuticals, Inc, Tarrytown, NY., Kamat V; Regeneron Pharmaceuticals, Inc, Tarrytown, NY., Hernandez AR; Regeneron Pharmaceuticals, Inc, Tarrytown, NY., Badithe A; Regeneron Pharmaceuticals, Inc, Tarrytown, NY., Ben LH; Regeneron Pharmaceuticals, Inc, Tarrytown, NY., Jones J; Regeneron Pharmaceuticals, Inc, Tarrytown, NY., Bautista J; Regeneron Pharmaceuticals, Inc, Tarrytown, NY., Yancopoulos GD; Regeneron Pharmaceuticals, Inc, Tarrytown, NY., Olson W; Regeneron Pharmaceuticals, Inc, Tarrytown, NY., Murphy AJ; Regeneron Pharmaceuticals, Inc, Tarrytown, NY., Sleeman MA; Regeneron Pharmaceuticals, Inc, Tarrytown, NY., Orengo JM; Regeneron Pharmaceuticals, Inc, Tarrytown, NY. Electronic address: jamie.orengo@regeneron.com.

المصدر: The Journal of allergy and clinical immunology [J Allergy Clin Immunol] 2022 Jan; Vol. 149 (1), pp. 200-211. Date of Electronic Publication: 2021 Jun 11.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.

بيانات الدورية: Publisher: Mosby Country of Publication: United States NLM ID: 1275002 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1097-6825 (Electronic) Linking ISSN: 00916749 NLM ISO Abbreviation: J Allergy Clin Immunol Subsets: MEDLINE

مواضيع طبية MeSH: Allergens/*immunology , Antibodies, Monoclonal/*pharmacology , Antigens, Plant/*immunology , Immunodominant Epitopes/*immunology , Immunoglobulin G/*pharmacology , Passive Cutaneous Anaphylaxis/*immunology, Animals ; Basophils/drug effects ; Basophils/immunology ; Humans ; Immunoglobulin E/immunology ; Mast Cells/drug effects ; Mast Cells/immunology ; Mice, Inbred BALB C ; Rhinitis, Allergic, Seasonal/blood ; Rhinitis, Allergic, Seasonal/immunology ; Mice