المؤلفون: Wu L; Department of Emergency and Critical Care Medicine, Changzheng Hospital, Naval Medical University, Shanghai, China.; Department of Emergency and Critical Care Medicine, Shanghai Pudong New Area People's Hospital, Shanghai, China., Xu D; Department of Pharmacy, Changzheng Hospital, Naval Medical University, Shanghai, China., Liu Y; Department of Pharmacy, Shanghai Pudong Hospital, Fudan University Pudong Medical Center, Shanghai, China., Li W; Department of Emergency and Critical Care Medicine, Changzheng Hospital, Naval Medical University, Shanghai, China., Jiang W; Department of Emergency and Critical Care Medicine, Changzheng Hospital, Naval Medical University, Shanghai, China., Tao X; Department of Pharmacy, Changzheng Hospital, Naval Medical University, Shanghai, China., Zhang J; Beijing Medicinovo Technology Co., Ltd, Beijing, China., Yu Z; Beijing Medicinovo Technology Co., Ltd, Beijing, China., Gao F; Beijing Medicinovo Technology Co., Ltd, Beijing, China., Chen W; Department of Pharmacy, Changzheng Hospital, Naval Medical University, Shanghai, China.; The SATCM Key Laboratory for New Resources & Quality Evaluation of Chinese Medicine, Institute of Chinese Materia Medica, Shanghai University of Traditional Chinese Medicine, Shanghai, China., Lin Z; Department of Emergency and Critical Care Medicine, Changzheng Hospital, Naval Medical University, Shanghai, China., Shan Y; Department of Emergency and Critical Care Medicine, Changzheng Hospital, Naval Medical University, Shanghai, China.

المصدر: Science progress [Sci Prog] 2024 Jul-Sep; Vol. 107 (3), pp. 368504241272696.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: SAGE Publications Country of Publication: England NLM ID: 0411361 Publication Model: Print Cited Medium: Internet ISSN: 2047-7163 (Electronic) Linking ISSN: 00368504 NLM ISO Abbreviation: Sci Prog Subsets: MEDLINE

مواضيع طبية MeSH: Intensive Care Units* , Length of Stay* , Glycoproteins*/therapeutic use , Multiple Organ Failure*/drug therapy , Multiple Organ Failure*/prevention & control , Multiple Organ Failure*/mortality , Respiration, Artificial*, Humans ; Male ; Female ; Middle Aged ; Retrospective Studies ; Aged ; Critical Illness ; Propensity Score ; Organ Dysfunction Scores ; Risk Factors ; Hospital Mortality

المؤلفون: Srdić T; Faculty of Biology, University of Belgrade, 11000 Belgrade, Serbia., Đurašević S; Faculty of Biology, University of Belgrade, 11000 Belgrade, Serbia., Lakić I; Faculty of Biology, University of Belgrade, 11000 Belgrade, Serbia., Ružičić A; Faculty of Biology, University of Belgrade, 11000 Belgrade, Serbia., Vujović P; Faculty of Biology, University of Belgrade, 11000 Belgrade, Serbia., Jevđović T; Faculty of Biology, University of Belgrade, 11000 Belgrade, Serbia., Dakić T; Faculty of Biology, University of Belgrade, 11000 Belgrade, Serbia., Đorđević J; Faculty of Biology, University of Belgrade, 11000 Belgrade, Serbia., Tosti T; Institute of Chemistry, Technology and Metallurgy, National Institute of the Republic of Serbia, University of Belgrade, 11000 Belgrade, Serbia., Glumac S; School of Medicine, University of Belgrade, 11129 Belgrade, Serbia., Todorović Z; School of Medicine, University of Belgrade, 11129 Belgrade, Serbia., Jasnić N; Faculty of Biology, University of Belgrade, 11000 Belgrade, Serbia.

المصدر: International journal of molecular sciences [Int J Mol Sci] 2024 Jul 16; Vol. 25 (14). Date of Electronic Publication: 2024 Jul 16.

نوع المنشور: Journal Article; Review

بيانات الدورية: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067 (Electronic) Linking ISSN: 14220067 NLM ISO Abbreviation: Int J Mol Sci Subsets: MEDLINE

مواضيع طبية MeSH: Sepsis*/complications , Sepsis*/metabolism , Sepsis*/drug therapy , Sepsis*/microbiology , Multiple Organ Failure*/etiology , Multiple Organ Failure*/metabolism, Humans ; Animals ; Gastrointestinal Microbiome ; Oxidative Stress ; Anti-Inflammatory Agents/therapeutic use ; Anti-Inflammatory Agents/pharmacology

المؤلفون: Relja B; Department of Trauma, Hand, Plastic and Reconstructive Surgery, Translational and Experimental Trauma Research, University Hospital Ulm, Ulm University, Ulm, Germany., Ghezzi P; University of Urbino Carlo Bo, Urbino, Italy., Coldewey SM; University Hospital Jena, Jena, Germany., Pavlov VA; Feinstein Institutes for Medical Research, Manhasset, NY, United States., Bhatia M; Department of Pathology and Biomedical Science, University of Otago, Christchurch, New Zealand., Jungwirth B; Department of Anesthesiology and Intensive Care Medicine, University Hospital Ulm, Ulm University, Ulm, Germany., Thiemermann C; Queen Mary University of London, London, United Kingdom.

المصدر: Frontiers in immunology [Front Immunol] 2024 Jul 11; Vol. 15, pp. 1447892. Date of Electronic Publication: 2024 Jul 11 (Print Publication: 2024).

نوع المنشور: Editorial; Introductory Journal Article

بيانات الدورية: Publisher: Frontiers Research Foundation] Country of Publication: Switzerland NLM ID: 101560960 Publication Model: eCollection Cited Medium: Internet ISSN: 1664-3224 (Electronic) Linking ISSN: 16643224 NLM ISO Abbreviation: Front Immunol Subsets: MEDLINE

مواضيع طبية MeSH: Sepsis*/therapy , Multiple Organ Failure*/therapy , Multiple Organ Failure*/etiology , Wounds and Injuries*/therapy , Wounds and Injuries*/complications , Translational Research, Biomedical*, Humans ; Animals

المؤلفون: Yu J; Department of Critical Care Medicine, Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 310009, China; Department of Critical Care Medicine, Haiyan People's Hospital, Zhejiang 314300, China., Zhang K; Department of Critical Care Medicine, Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 310009, China., Chen T; Department of Emergency Medicine, Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou, 310016, China., Lin R; Department of Critical Care Medicine, Taizhou Municipal Hospital, Zhejiang, 318000, China., Chen Q; Intensive Care Unit, Ninghai First Hospital, Zhejiang, 315600, China., Chen C; Intensive Care Unit, Xiangshan First People's Hospital Medical and Health Group, Zhejiang, 315700, China., Tong M; Department of Neurosurgery, Affiliated Jinhua Hospital, Zhejiang University School of Medicine, Zhejiang, 321000, China., Chen J; Department of Emergency Medicine, Dongyang People' Hospital of Wenzhou Medical University, Zhejiang, 322100, China., Yu J; Department of Critical Care Medicine, Longquan People's Hospital, Zhejiang, 323700, China., Lou Y; Department of Critical Care Medicine, Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 310009, China., Xu P; Department of Critical Care Medicine, Taizhou Municipal Hospital, Zhejiang, 318000, China., Zhong C; Department of Critical Care Medicine, Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 310009, China; Intensive Care Unit, Ninghai First Hospital, Zhejiang, 315600, China., Chen Q; Intensive Care Unit, Xiangshan First People's Hospital Medical and Health Group, Zhejiang, 315700, China., Sun K; Department of Emergency Medicine, Dongyang People' Hospital of Wenzhou Medical University, Zhejiang, 322100, China., Liu L; Department of Critical Care Medicine, Longquan People's Hospital, Zhejiang, 323700, China., Cao L; Department of Critical Care Medicine, Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 310009, China., Zheng C; Department of Critical Care Medicine, Taizhou Municipal Hospital, Zhejiang, 318000, China., Wang P; Intensive Care Unit, Ninghai First Hospital, Zhejiang, 315600, China., Chen Q; Department of Neurosurgery, Affiliated Jinhua Hospital, Zhejiang University School of Medicine, Zhejiang, 321000, China., Yang Q; Department of Neurosurgery, Affiliated Jinhua Hospital, Zhejiang University School of Medicine, Zhejiang, 321000, China., Chen W; Department of Critical Care Medicine, Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 310009, China; Department of Emergency and Intensive Care Unit, The First People's Hospital of Linhai, Taizhou, Zhejiang 317000, China., Wang X; Department of Cardiovascular Surgery, Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 310009, China., Yan Z; Department of Critical Care Medicine, Haiyan People's Hospital, Zhejiang 314300, China., Zhang X; Department of Critical Care Medicine, Second Affiliated Hospital, Jiaxing College School of Medicine, Jiaxing 314031, China., Cui W; Department of Critical Care Medicine, Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 310009, China., Chen L; Department of Neurosurgery, Affiliated Jinhua Hospital, Zhejiang University School of Medicine, Zhejiang, 321000, China., Zhang Z; Department of Emergency Medicine, Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou, 310016, China., Zhang G; Department of Critical Care Medicine, Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 310009, China; Key Laboratory of Multiple Organ Failure (Zhejiang University), Ministry of Education, Hangzhou 310009, China. Electronic address: genshengzhang@zju.edu.cn.

المصدر: International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases [Int J Infect Dis] 2024 Jul; Vol. 144, pp. 107045. Date of Electronic Publication: 2024 Apr 10.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Elsevier Country of Publication: Canada NLM ID: 9610933 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1878-3511 (Electronic) Linking ISSN: 12019712 NLM ISO Abbreviation: Int J Infect Dis Subsets: MEDLINE

مواضيع طبية MeSH: COVID-19*/mortality , COVID-19*/complications , COVID-19*/physiopathology , Intensive Care Units* , Multiple Organ Failure*/mortality , Multiple Organ Failure*/etiology , Organ Dysfunction Scores* , SARS-CoV-2*, Humans ; Male ; Female ; Middle Aged ; Aged ; APACHE ; Hospitalization ; Hospital Mortality

المؤلفون: Bestle MH; Department of Anaesthesia and Intensive Care, Copenhagen University Hospital-North Zealand, Hilleroed, Denmark.; Department of Clinical Medicine, University of Copenhagen, Copenhagen, Denmark., Stensballe J; Capital Region Blood Bank, Copenhagen University Hospital-Rigshospitalet, Copenhagen, Denmark.; Department of Anesthesiology and Trauma, Centre of Head and Ortopaedics, Copenhagen University Hospital-Rigshospitalet, Copenhagen, Denmark., Lange T; Section of Biostatistics, University of Copenhagen, Copenhagen, Denmark., Clausen NE; Department of Anaesthesia and Intensive Care, Copenhagen University Hospital-Bispebjerg and Frederiksberg, Copenhagen, Denmark., Søe-Jensen P; Department of Anaesthesia and Intensive Care, Copenhagen University Hospital-Herlev and Gentofte, Copenhagen, Denmark., Pedersen KH; Capital Region Blood Bank, Copenhagen University Hospital-Rigshospitalet, Copenhagen, Denmark., Gybel-Brask M; Capital Region Blood Bank, Copenhagen University Hospital-Rigshospitalet, Copenhagen, Denmark., Kjær MN; Department of Intensive Care, Copenhagen University Hospital-Rigshospitalet, Copenhagen, Denmark., Steensen CO; Department of Intensive Care, Copenhagen University Hospital-Rigshospitalet, Copenhagen, Denmark., Jensen DB; Department of Anaesthesia and Intensive Care, Copenhagen University Hospital-Bispebjerg and Frederiksberg, Copenhagen, Denmark., Gärtner R; Department of Anaesthesia and Intensive Care, Copenhagen University Hospital-Bispebjerg and Frederiksberg, Copenhagen, Denmark., Schønemann-Lund M; Department of Anaesthesia and Intensive Care, Copenhagen University Hospital-North Zealand, Hilleroed, Denmark., Kristiansen KT; Department of Anaesthesia and Intensive Care, Copenhagen University Hospital-Amager and Hvidovre, Copenhagen, Denmark., Lindhardt A; Department of Anaesthesia and Intensive Care, Copenhagen University Hospital-Zealand University Hospital, Koege, Denmark., Johansson PI; Capital Region Blood Bank, Copenhagen University Hospital-Rigshospitalet, Copenhagen, Denmark., Perner A; Department of Clinical Medicine, University of Copenhagen, Copenhagen, Denmark.; Department of Intensive Care, Copenhagen University Hospital-Rigshospitalet, Copenhagen, Denmark.

المصدر: JAMA network open [JAMA Netw Open] 2024 Sep 03; Vol. 7 (9), pp. e2432444. Date of Electronic Publication: 2024 Sep 03.

نوع المنشور: Journal Article; Randomized Controlled Trial; Multicenter Study

بيانات الدورية: Publisher: American Medical Association Country of Publication: United States NLM ID: 101729235 Publication Model: Electronic Cited Medium: Internet ISSN: 2574-3805 (Electronic) Linking ISSN: 25743805 NLM ISO Abbreviation: JAMA Netw Open Subsets: MEDLINE

مواضيع طبية MeSH: Iloprost*/therapeutic use , Shock, Septic*/drug therapy , Shock, Septic*/mortality , Multiple Organ Failure*/drug therapy , Multiple Organ Failure*/mortality , Organ Dysfunction Scores*, Humans ; Male ; Female ; Middle Aged ; Double-Blind Method ; Aged ; Denmark ; Thrombomodulin/therapeutic use ; Endothelium, Vascular/drug effects ; Endothelium, Vascular/physiopathology ; Intensive Care Units

المؤلفون: Cobert J; Anesthesia Service, San Francisco VA Health Care System, San Francisco, CA; Department of Anesthesiology, University of California San Francisco, San Francisco, CA; Critical Care and Perioperative Population Health Research (CAPER) Unit, Department of Anesthesiology, Duke University Medical Center, Durham, NC. Electronic address: Julien.Cobert@ucsf.edu., Frere Z; Yale University. Department of Statistics. New Haven, CT., Wongsripuemtet P; Critical Care and Perioperative Population Health Research (CAPER) Unit, Department of Anesthesiology, Duke University Medical Center, Durham, NC; Department of Anesthesiology, Faculty of Medicine, Siriraj Hospital, Mahidol University, Bangkok, Thailand., Ohnuma T; Department of Anesthesiology, University of California San Francisco, San Francisco, CA; Department of Anesthesiology, Duke University, Durham, NC., Krishnamoorthy V; Department of Anesthesiology, University of California San Francisco, San Francisco, CA; Department of Anesthesiology, Duke University, Durham, NC; Department of Population Health Sciences, Duke University, Durham, NC., Fuller M; Department of Anesthesiology, University of California San Francisco, San Francisco, CA; Department of Anesthesiology, Duke University, Durham, NC., Chapman AC; Palliative Medicine, Department of Internal Medicine, University of California San Francisco, San Francisco, CA; Department of Surgery, University of California San Francisco, San Francisco, CA., Yaport M; Department of Anesthesiology, University of California San Francisco, San Francisco, CA; Department of Anesthesiology, Duke University, Durham, NC., Ghadimi K; Department of Anesthesiology, University of California San Francisco, San Francisco, CA; Department of Anesthesiology, Duke University, Durham, NC., Bartz R; Department of Anesthesiology, Brigham and Women's Hospital, Harvard University. Boston, MA., Raghunathan K; Critical Care and Perioperative Population Health Research (CAPER) Unit, Department of Anesthesiology, Duke University Medical Center, Durham, NC; Department of Anesthesiology, Duke University, Durham, NC; Department of Population Health Sciences, Duke University, Durham, NC; Anesthesia Service, Durham VA Healthcare System. Durham, NC.

المصدر: Journal of cardiothoracic and vascular anesthesia [J Cardiothorac Vasc Anesth] 2024 Sep; Vol. 38 (9), pp. 1987-1995. Date of Electronic Publication: 2024 Apr 27.

نوع المنشور: Journal Article; Multicenter Study

بيانات الدورية: Publisher: W.B. Saunders Country of Publication: United States NLM ID: 9110208 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1532-8422 (Electronic) Linking ISSN: 10530770 NLM ISO Abbreviation: J Cardiothorac Vasc Anesth Subsets: MEDLINE

مواضيع طبية MeSH: Cardiac Surgical Procedures*/trends , Cardiac Surgical Procedures*/mortality , Multiple Organ Failure*/epidemiology , Multiple Organ Failure*/mortality, Humans ; Male ; Retrospective Studies ; Female ; United States/epidemiology ; Middle Aged ; Aged ; Adult ; Postoperative Complications/epidemiology ; Hospital Mortality/trends ; Risk Factors ; Cohort Studies

المؤلفون: Tang F; State Key Laboratory of Southwestern Chinese Medicine Resources, Chengdu University of Traditional Chinese Medicine, Chengdu 611137, China. Electronic address: tangfei0227@163.com., Zhao XL; State Key Laboratory of Southwestern Chinese Medicine Resources, Chengdu University of Traditional Chinese Medicine, Chengdu 611137, China. Electronic address: zhaoxiaolan1999@163.com., Xu LY; State Key Laboratory of Southwestern Chinese Medicine Resources, Chengdu University of Traditional Chinese Medicine, Chengdu 611137, China. Electronic address: xuliyue1029@163.com., Zhang JN; State Key Laboratory of Southwestern Chinese Medicine Resources, Chengdu University of Traditional Chinese Medicine, Chengdu 611137, China. Electronic address: zhangjingnan0123@163.com., Ao H; State Key Laboratory of Southwestern Chinese Medicine Resources, Chengdu University of Traditional Chinese Medicine, Chengdu 611137, China; Innovative Institute of Chinese Medicine and Pharmacy, Chengdu University of Traditional Chinese Medicine, Chengdu 611137, China. Electronic address: aohui2005@126.com., Peng C; State Key Laboratory of Southwestern Chinese Medicine Resources, Chengdu University of Traditional Chinese Medicine, Chengdu 611137, China. Electronic address: pengchengcxy@126.com.

المصدر: Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie [Biomed Pharmacother] 2024 Sep; Vol. 178, pp. 117180. Date of Electronic Publication: 2024 Jul 27.

نوع المنشور: Journal Article; Review

بيانات الدورية: Publisher: Editions Scientifiques Elsevier Country of Publication: France NLM ID: 8213295 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1950-6007 (Electronic) Linking ISSN: 07533322 NLM ISO Abbreviation: Biomed Pharmacother Subsets: MEDLINE

مواضيع طبية MeSH: Multiple Organ Failure*/etiology , Multiple Organ Failure*/physiopathology , Sepsis*/physiopathology , Sepsis*/complications , Endothelium, Vascular*/physiopathology , Endothelium, Vascular*/drug effects, Humans ; Animals ; Endothelial Cells/metabolism

المؤلفون: Song L; Northern Jiangsu People's Hospital Affiliated to Yangzhou University, Yangzhou, China.; Intensive Care Unit, Northern Jiangsu People's Hospital, Yangzhou, China., Jiang W; Northern Jiangsu People's Hospital Affiliated to Yangzhou University, Yangzhou, China.; Intensive Care Unit, Northern Jiangsu People's Hospital, Yangzhou, China., Lin H; Northern Jiangsu People's Hospital Affiliated to Yangzhou University, Yangzhou, China.; Intensive Care Unit, Northern Jiangsu People's Hospital, Yangzhou, China., Yu J; Northern Jiangsu People's Hospital Affiliated to Yangzhou University, Yangzhou, China.; Intensive Care Unit, Northern Jiangsu People's Hospital, Yangzhou, China., Liu K; Northern Jiangsu People's Hospital Affiliated to Yangzhou University, Yangzhou, China., Zheng R; Northern Jiangsu People's Hospital Affiliated to Yangzhou University, Yangzhou, China.; Intensive Care Unit, Northern Jiangsu People's Hospital, Yangzhou, China.

المصدر: Frontiers in immunology [Front Immunol] 2024 Aug 21; Vol. 15, pp. 1461051. Date of Electronic Publication: 2024 Aug 21 (Print Publication: 2024).

نوع المنشور: Journal Article; Review

بيانات الدورية: Publisher: Frontiers Research Foundation] Country of Publication: Switzerland NLM ID: 101560960 Publication Model: eCollection Cited Medium: Internet ISSN: 1664-3224 (Electronic) Linking ISSN: 16643224 NLM ISO Abbreviation: Front Immunol Subsets: MEDLINE

مواضيع طبية MeSH: Sepsis*/metabolism , Protein Processing, Post-Translational* , Multiple Organ Failure*/metabolism , Multiple Organ Failure*/etiology , Multiple Organ Failure*/immunology, Humans ; Animals ; Signal Transduction

المؤلفون: Ware LB; Vanderbilt University Medical Center, Nashville, Tennessee., Files DC; Wake Forest University, Winston Salem, North Carolina., Fowler A; Viginia Commonwealth University, Richmond., Aboodi MS; Montefiore Medical Center, New York, New York., Aggarwal NR; University of Colorado School of Medicine, Aurora., Brower RG; Johns Hopkins University, Baltimore, MD., Chang SY; University of California, Los Angeles., Douglas IS; Denver Health Medical Center, Denver, Colorado., Fields S; University of California, San Francisco., Foulkes AS; Massachusetts General Hospital, Boston., Ginde AA; University of Colorado School of Medicine, Aurora., Harris ES; University of Utah, Salt Lake City., Hendey GW; University of California, Los Angeles., Hite RD; University of Cincinnati, Cincinnati, Ohio., Huang W; Massachusetts General Hospital, Boston., Lai P; Massachusetts General Hospital, Boston., Liu KD; University of California, San Francisco., Thompson BT; Massachusetts General Hospital, Boston., Matthay MA; University of California, San Francisco.

مؤلفون مشاركون: National Heart, Lung, and Blood Institute Prevention and Early Treatment of Acute Lung Injury Clinical Trials Network

المصدر: JAMA [JAMA] 2024 Aug 06; Vol. 332 (5), pp. 390-400.

نوع المنشور: Clinical Trial, Phase II; Journal Article; Multicenter Study; Randomized Controlled Trial; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.

بيانات الدورية: Publisher: American Medical Association Country of Publication: United States NLM ID: 7501160 Publication Model: Print Cited Medium: Internet ISSN: 1538-3598 (Electronic) Linking ISSN: 00987484 NLM ISO Abbreviation: JAMA Subsets: MEDLINE

مواضيع طبية MeSH: Acetaminophen*/administration & dosage , Acetaminophen*/adverse effects , Acetaminophen*/therapeutic use , Analgesics, Non-Narcotic*/administration & dosage , Analgesics, Non-Narcotic*/adverse effects , Analgesics, Non-Narcotic*/therapeutic use , Critical Illness*/therapy , Multiple Organ Failure*/diagnosis , Multiple Organ Failure*/etiology , Multiple Organ Failure*/prevention & control , Organ Dysfunction Scores* , Sepsis*/drug therapy , Sepsis*/complications, Aged ; Female ; Humans ; Male ; Middle Aged ; Double-Blind Method ; Hemoglobins/analysis ; Renal Replacement Therapy ; Respiration, Artificial ; Infusions, Intravenous

المؤلفون: Tavares CAM; Hospital Israelita Albert Einstein, São Paulo, São Paulo, Brazil.; Geriatric Cardiology Unit, Instituto do Coração do Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil., Azevedo LCP; Hospital Israelita Albert Einstein, São Paulo, São Paulo, Brazil., Rea-Neto Á; Center for Studies and Research in Intensive Care Medicine, Curitiba, Brazil.; Internal Medicine Department, Hospital de Clínicas, Federal University of Paraná, Curitiba, Brazil.; Hospital Santa Casa Curitiba, Curitiba, Brazil., Campos NS; Hospital Israelita Albert Einstein, São Paulo, São Paulo, Brazil.; Hospital M´Boi Mirim, São Paulo, Brazil., Amendola CP; Hospital de Câncer de Barretos, Barretos, Brazil., Kozesinski-Nakatani AC; Center for Studies and Research in Intensive Care Medicine, Curitiba, Brazil.; Internal Medicine Department, Hospital de Clínicas, Federal University of Paraná, Curitiba, Brazil.; Hospital Santa Casa Curitiba, Curitiba, Brazil., David-João PG; Hospital M´Boi Mirim, São Paulo, Brazil., Lobo SM; Intensive Care Division, Hospital de Base, Faculdade de Medicina de São José do Rio Preto, São José do Rio Preto, Brazil., Filiponi TC; Hospital Universitário São Francisco de Assis na Providência de Deus, Bragança Paulista, Brazil., Almeida GMB; Hospital de Emergência Dr Daniel Houly, Arapiraca, Brazil., Bergo RR; Hospital Santa Lucia, Poços de Caldas, Brazil., Guimarães-Júnior MRR; Santa Casa de Misericórdia de Barretos, Barretos, Brazil., Figueiredo RC; Hospital Maternidade São José, Colatina, Brazil., Castro JR; Hospital Municipal de Aparecida de Goiânia, Aparecida de Goiânia, Brazil., Schuler CJ; Hospital Nossa Senhora de Oliveira, Vacaria, Brazil., Westphal GA; Centro Hospitalar Unimed, Joinville, Brazil., Carioca ACR; Hospital Israelita Albert Einstein, São Paulo, São Paulo, Brazil., Monfradini F; Hospital Israelita Albert Einstein, São Paulo, São Paulo, Brazil., Nieri J; Hospital Israelita Albert Einstein, São Paulo, São Paulo, Brazil., Neves FMO; Hospital Israelita Albert Einstein, São Paulo, São Paulo, Brazil., Paulo JA; Hospital Israelita Albert Einstein, São Paulo, São Paulo, Brazil., Albuquerque CSN; Hospital Israelita Albert Einstein, São Paulo, São Paulo, Brazil., Silva MCR; Hospital Israelita Albert Einstein, São Paulo, São Paulo, Brazil., Kosiborod MN; Department of Cardiovascular Disease, Saint Luke's Mid America Heart Institute, University of Missouri-Kansas City School of Medicine, Kansas City., Pereira AJ; Hospital Israelita Albert Einstein, São Paulo, São Paulo, Brazil., Damiani LP; Hospital Israelita Albert Einstein, São Paulo, São Paulo, Brazil., Corrêa TD; Hospital Israelita Albert Einstein, São Paulo, São Paulo, Brazil., Serpa-Neto A; Hospital Israelita Albert Einstein, São Paulo, São Paulo, Brazil.; Australian and New Zealand Intensive Care Research Centre, School of Public Health and Preventive Medicine, Monash University, Melbourne, Australia.; Department of Intensive Care, Austin Hospital, Melbourne, Australia., Berwanger O; Hospital Israelita Albert Einstein, São Paulo, São Paulo, Brazil.; George Institute for Global Health, London, United Kingdom.; Imperial College London, London, United Kingdom., Zampieri FG; Hospital Israelita Albert Einstein, São Paulo, São Paulo, Brazil.; Department of Critical Care Medicine, Faculty of Medicine and Dentistry, University of Alberta and Alberta Health Services, Edmonton, Canada.

مؤلفون مشاركون: DEFENDER Investigators

المصدر: JAMA [JAMA] 2024 Aug 06; Vol. 332 (5), pp. 401-411.

نوع المنشور: Journal Article; Multicenter Study; Randomized Controlled Trial; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: American Medical Association Country of Publication: United States NLM ID: 7501160 Publication Model: Print Cited Medium: Internet ISSN: 1538-3598 (Electronic) Linking ISSN: 00987484 NLM ISO Abbreviation: JAMA Subsets: MEDLINE

مواضيع طبية MeSH: Benzhydryl Compounds*/therapeutic use , Critical Illness*/therapy , Glucosides*/therapeutic use , Glucosides*/adverse effects , Multiple Organ Failure*/drug therapy , Multiple Organ Failure*/mortality , Sodium-Glucose Transporter 2 Inhibitors*/therapeutic use , Sodium-Glucose Transporter 2 Inhibitors*/adverse effects, Aged ; Female ; Humans ; Male ; Middle Aged ; Hospital Mortality ; Intensive Care Units ; Length of Stay ; Renal Replacement Therapy ; Brazil