يعرض 1 - 10 نتائج من 15 نتيجة بحث عن '"Ornella Tolhurst"', وقت الاستعلام: 1.03s تنقيح النتائج
  1. 1
    دورية أكاديمية
    Dual targeting of the epigenome via FACT complex and histone deacetylase is a potent treatment strategy for DIPG

    المؤلفون: Anahid Ehteda, Sandy Simon, Laura Franshaw, Federico M. Giorgi, Jie Liu, Swapna Joshi, Jourdin R.C. Rouaen, Chi Nam Ignatius Pang, Ruby Pandher, Chelsea Mayoh, Yujie Tang, Aaminah Khan, Caitlin Ung, Ornella Tolhurst, Anne Kankean, Elisha Hayden, Rebecca Lehmann, Sylvie Shen, Anjana Gopalakrishnan, Peter Trebilcock, Katerina Gurova, Andrei V. Gudkov, Murray D. Norris, Michelle Haber, Orazio Vittorio, Maria Tsoli, David S. Ziegler

    المصدر: Cell Reports, Vol 35, Iss 2, Pp 108994- (2021)

    مصطلحات موضوعية: DIPG, brainstem glioma, H3K27M, facilitates chromatin transcription complex, HDAC, EZH2, Biology (General), QH301-705.5

    وصف الملف: electronic resource

    Relation: http://www.sciencedirect.com/science/article/pii/S2211124721003089; https://doaj.org/toc/2211-1247

    URL الوصول: https://doaj.org/article/f3c43c1ed6e44cbd8f4c250a0e00921a

    View record from ScienceDirect Full Text Finder
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  2. 2
    Dual targeting of the epigenome via FACT complex and histone deacetylase is a potent treatment strategy for DIPG

    المؤلفون: Swapna Joshi, Murray D. Norris, Sandy Simon, Orazio Vittorio, Sylvie Shen, Andrei V. Gudkov, Ornella Tolhurst, Anahid Ehteda, Caitlin Ung, Jourdin R. C. Rouaen, Ruby Pandher, Aaminah Khan, Michelle Haber, Elisha Hayden, Laura Franshaw, Rebecca Lehmann, Chelsea Mayoh, Yujie Tang, Katerina Gurova, David S. Ziegler, Maria Tsoli, Federico M. Giorgi, Anjana Gopalakrishnan, Jie Liu, Chi Nam Ignatius Pang, Anne Kankean, Peter Trebilcock

    المساهمون: Ehteda A., Simon S., Franshaw L., Giorgi F.M., Liu J., Joshi S., Rouaen J.R.C., Pang C.N.I., Pandher R., Mayoh C., Tang Y., Khan A., Ung C., Tolhurst O., Kankean A., Hayden E., Lehmann R., Shen S., Gopalakrishnan A., Trebilcock P., Gurova K., Gudkov A.V., Norris M.D., Haber M., Vittorio O., Tsoli M., Ziegler D.S.

    المصدر: Cell Reports, Vol 35, Iss 2, Pp 108994-(2021)

    مصطلحات موضوعية: 0301 basic medicine, xenograft model, Cell Cycle Proteins, Retinoblastoma Protein, Epigenesis, Genetic, Histones, Epigenome, Mice, chemistry.chemical_compound, 0302 clinical medicine, facilitates chromatin transcription complex, HDAC, Panobinostat, Brain Stem Neoplasms, Biology (General), Child, EZH2, Histone deacetylase inhibitor, High Mobility Group Proteins, Acetylation, Drug Synergism, Chromatin, pediatric cancer, DNA-Binding Proteins, DIPG, Transcriptional Elongation Factors, Neuroglia, Signal Transduction, medicine.drug_class, QH301-705.5, Primary Cell Culture, Carbazoles, Antineoplastic Agents, Methylation, General Biochemistry, Genetics and Molecular Biology, Chromatin remodeling, 03 medical and health sciences, H3K27M, Cell Line, Tumor, medicine, Animals, Humans, anticancer therapy, Histone H3 acetylation, Diffuse Intrinsic Pontine Glioma, brainstem glioma, Survival Analysis, Xenograft Model Antitumor Assays, Pediatric cancer, 030104 developmental biology, chemistry, E2F1, Cancer research, Histone deacetylase, Tumor Suppressor Protein p53, E2F1 Transcription Factor, 030217 neurology & neurosurgery, Transcription Factors

    وصف الملف: ELETTRONICO

    URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ccbee79680e90f0fba780fc68415fa1d
    https://hdl.handle.net/11585/831846

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  3. 3
    Dual Targeting of the Epigenome Via Facilitates Chromatin Transcription Complex (FACT) and Histone Deacetylase is a Potent Treatment Strategy for DIPG

    المؤلفون: Michelle Haber, Ornella Tolhurst, Murray D. Norris, Aaminah Khan, Sylvie Shen, Maria Tsoli, Jie Liu, Caitlin Ung, Orazio Vittorio, Yujie Tang, Andrei V. Gudkov, Jourdin R. C. Rouaen, Peter Trebilcock, Federico M. Giorgi, Chi Nam Ignatius Pang, Anjana Gopalakrishnan, Elisha Hayden, Swapna Joshi, Sandy Simon, David S. Ziegler, Chelsea Mayoh, Anahid Ehteda, Anne Kankean, Katerina Gurova, Ruby Pandher, Laura Franshaw

    المصدر: SSRN Electronic Journal.

    مصطلحات موضوعية: chemistry.chemical_compound, Histone, chemistry, biology, Panobinostat, EZH2, Cancer research, biology.protein, E2F1, Histone deacetylase, Epigenome, Epigenetics, Chromatin

    URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::23d1fb035d52de9fabce6e699861b962
    https://doi.org/10.2139/ssrn.3664176

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  4. 4
    DIPG-27. TARGETING FACILITATES CHROMATIN TRANSCRIPTION (FACT) AS A NOVEL STRATEGY FOR DIFFUSE INTRINSIC PONTINE GLIOMA (DIPG) THAT ENHANCES RESPONSE TO HISTONE DEACETYLASE (HDAC) INHIBITION

    المؤلفون: Sandy Simon, Jie Liu, Katerina Gurova, Michelle Haber, Sandra George, Ruby Pandher, Laura Franshaw, Anahid Ehteda, Orazio Vittorio, Elisha Hayden, Caitlin Ung, Murray D. Norris, Maria Tsoli, Rebecca Lehmann, Anjana Gopalakrishnan, Federico M. Giorgi, Swapna Joshi, Ornella Tolhurst, Andrei Gudkov, Aaminah Khan, Dannielle Upton, David S. Ziegler, Peter Trebilcock, Chelsea Mayoh, Chi Nam Ignatius Pang

    المصدر: Neuro-Oncology

    مصطلحات موضوعية: Cancer Research, Retinoblastoma, Diffuse Midline Glioma/DIPG, medicine.disease, Chromatin, chemistry.chemical_compound, Histone H3, Oncology, chemistry, Acetylation, Transcription (biology), Panobinostat, Cancer research, medicine, AcademicSubjects/MED00300, AcademicSubjects/MED00310, Neurology (clinical), Histone deacetylase, Signal transduction

    URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d29680a7ddb4562e585fcc50def881d
    https://doi.org/10.1093/neuonc/noaa222.076

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  5. 5
    THER-23. RESULTS OF THE ZERO CHILDHOOD CANCER INTEGRATED PRECISION MEDICINE PLATFORM FOR PAEDIATRIC HIGH-RISK BRAIN TUMOURS

    المؤلفون: Tracey A. O'Brien, Patrick Strong, Anjana Gopalakrishnan, Katherine M. Tucker, Amit Kumar, Dylan Grebert-Wade, Glenn M. Marshall, Tim Failes, Alexandra Sherstyuk, Vanessa Tyrrell, Richard B. Lock, David S. Ziegler, Caitlin Ung, Marc Cowley, Dong Anh Khuong Quang, Paulette Barahona, Chelsea Mayoh, Toby Trahair, Ornella Tolhurst, Greg M. Arndt, Maria Tsoli, Marie Wong, Michelle Haber, Andrew J. Gifford, Peter Trebilcock, Meera Warby, Loretta Lau, Murray D. Norris, Paul G Ekert, Emily Mould

    المصدر: Neuro-Oncology. 21:ii118-ii118

    مصطلحات موضوعية: Oncology, Cancer Research, medicine.medical_specialty, business.industry, Childhood cancer, Cancer, medicine.disease, Precision medicine, Internal medicine, medicine, Neurology (clinical), Translational Therapeutics, business, Platelet-Derived Growth Factor alpha Receptor, Protein p53

    URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c9b8327ad577dcae3b9931d28c97f453
    https://doi.org/10.1093/neuonc/noz036.228

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  6. 6
    A simple, accurate and universal method for quantification of PCR

    المؤلفون: K. A. Duggan, Stephen D. Schibeci, Ornella Tolhurst, George Hodge, Ulla Simanainen, Francia Garces Suarez, Tegan Hunter, Edward Hendriks, Nicky Boulter, David J. Handelsman, Trevor Sunderland

    المصدر: BMC Biotechnology

    مصطلحات موضوعية: 0301 basic medicine, Quantification methods, Absolute quantification, Gene Expression, Computational biology, Biology, Real-Time Polymerase Chain Reaction, Bioinformatics, Mice, 03 medical and health sciences, 0302 clinical medicine, Dna genetics, Simple (abstract algebra), Animals, Humans, Cells, Cultured, Methodology Article, DNA, Amplicon, Universal calibrator, qPCR, 030104 developmental biology, 030220 oncology & carcinogenesis, Calibration, Leukocytes, Mononuclear, DECIPHER, Biotechnology

    URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::12e0988823fd584417eeac0cc25cac15
    https://doi.org/10.1186/s12896-016-0256-y

    Find this article in full text from Springer Verlag. Find this article in full text from ProQuest
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  7. 7
    Expression of doublecortin (DCX) and doublecortin-like kinase (DCLK) within the developing chick brain

    المؤلفون: Joanne M. Dunn, Peter L. Jeffrey, Ornella Tolhurst, Amanda Capes-Davis

    المصدر: Developmental Dynamics. 232:457-467

    مصطلحات موضوعية: Doublecortin Domain Proteins, Cerebellum, Doublecortin Protein, Time Factors, Molecular Sequence Data, Lissencephaly, Chick Embryo, Protein Serine-Threonine Kinases, Cell membrane, Purkinje Cells, Doublecortin-Like Kinases, Cell Movement, medicine, Animals, Amino Acid Sequence, Cloning, Molecular, In Situ Hybridization, Neurons, Cloning, Mammalian nervous system, Microscopy, Confocal, Base Sequence, biology, Reverse Transcriptase Polymerase Chain Reaction, Cerebrum, Kinase, Neuropeptides, Brain, Gene Expression Regulation, Developmental, Anatomy, Blotting, Northern, medicine.disease, Immunohistochemistry, Doublecortin, Cell biology, medicine.anatomical_structure, nervous system, biology.protein, RNA, Microtubule-Associated Proteins, Developmental Biology

    URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b4ac2d717e8e575fc559b1a541cf9145
    https://doi.org/10.1002/dvdy.20240

    View record at Wiley
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  8. 8
    Epigenetic factors controlling the development of avian Purkinje neurons

    المؤلفون: Peter L. Jeffrey, Ornella Tolhurst, J. Meaney, Ron P. Weinberger

    المصدر: Journal of Neuroscience Methods. 67:163-175

    مصطلحات موضوعية: Cerebellum, General Neuroscience, Biology, Granule cell, Calbindin, Cell aggregation, medicine.anatomical_structure, nervous system, Cell culture, medicine, Neuroglia, Neuron, Neuroscience, Astrocyte

    URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::1260612076625fda7d3864701ace95c0
    https://doi.org/10.1016/0165-0270(96)00044-1

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  9. 9
    CCAAT/enhancer binding protein-δ expression by dendritic cells regulates CNS autoimmune inflammatory disease

    المؤلفون: Samuel N. Breit, Mohammad G. Mohammad, Ornella Tolhurst, Paul E. Sawchenko, David Brown, Vicky Wang-Wei Tsai

    مصطلحات موضوعية: CCAAT-Enhancer-Binding Protein-delta, Encephalomyelitis, Autoimmune, Experimental, Biology, T-Lymphocytes, Regulatory, Article, Myelin oligodendrocyte glycoprotein, Mice, Immune system, Enhancer binding, medicine, Animals, Transcription factor, Mice, Knockout, Ccaat-enhancer-binding proteins, General Neuroscience, Experimental autoimmune encephalomyelitis, Dendritic cell, Dendritic Cells, medicine.disease, Interleukin-10, Up-Regulation, Interleukin 10, Myelin-Associated Glycoprotein, Astrocytes, Immunology, biology.protein, Th17 Cells

    URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb2f2f066eb19a9039368a8f6ce1f934
    https://europepmc.org/articles/PMC3334319/

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  10. 10
    Induction of neuron-specific tropomyosin mRNAs by nerve growth factor is dependent on morphological differentiation

    المؤلفون: Peter W. Gunning, Ron P. Weinberger, Peter L. Jeffrey, Ornella Tolhurst, R. C. Henke

    المصدر: The Journal of Cell Biology

    مصطلحات موضوعية: Neurite, RNA Splicing, Cellular differentiation, Molecular Sequence Data, Tropomyosin, Biology, PC12 Cells, Polymerase Chain Reaction, Cerebellum, Gene expression, medicine, Animals, Nerve Growth Factors, RNA, Messenger, Neurons, Regulation of gene expression, Base Sequence, Cell Differentiation, Articles, Cell Biology, Anatomy, Rats, Cell biology, Actin Cytoskeleton, Nerve growth factor, medicine.anatomical_structure, Gene Expression Regulation, Oligodeoxyribonucleotides, nervous system, Cell culture, Neuron

    URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fa004e37eb34249699c9dad89e0beb91
    https://doi.org/10.1083/jcb.120.1.205

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