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1دورية أكاديمية
المؤلفون: Gabriel B. Borja, Hongkang Zhang, Benjamin N. Harwood, Jane Jacques, Jennifer Grooms, Romina O. Chantre, Dawei Zhang, Adam Barnett, Christopher A. Werley, Yang Lu, Steven F. Nagle, Owen B. McManus, Graham T. Dempsey
المصدر: Frontiers in Molecular Neuroscience, Vol 15 (2022)
مصطلحات موضوعية: optogenetics, optopatch, high-throughput screening, ion channels, voltage-gated sodium channels, pain, Neurosciences. Biological psychiatry. Neuropsychiatry, RC321-571
وصف الملف: electronic resource
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المؤلفون: Pin W. Liu, Hongkang Zhang, Christopher A. Werley, Monika Pichler, Steve Ryan, Caitlin Lewarch, Jane Jacques, Jennifer Grooms, John Ferrante, Guangde Li, Dawei Zhang, Nate Bremmer, Adam Barnett, Romina Chantre, Amy E. Elder, Adam E. Cohen, Luis A. Williams, Graham T. Dempsey, Owen B. McManus
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::088799b6f5f999c7b434c1b6a4461ccb
https://doi.org/10.1101/2022.12.12.520139 -
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المؤلفون: Dina Simkin, Christina Ambrosi, Kelly A. Marshall, Luis A. Williams, Jordyn Eisenberg, Mennat Gharib, Graham T. Dempsey, Alfred L. George, Owen B. McManus, Evangelos Kiskinis
المصدر: Trends Pharmacol Sci
مصطلحات موضوعية: Pharmacology, Neurons, Epilepsy, Induced Pluripotent Stem Cells, Mutation, Humans, Channelopathies, Toxicology, Child, Article
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::30dfd020322e7bbc3d826e842e56c497
https://europepmc.org/articles/PMC9119009/ -
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المؤلفون: Owen B. McManus, Vivian Hecht, Violeta Yu, Chris M Hempel, Graham T. Dempsey, Ryan J. Babcock, Michael Jarosh, Joseph G. McGivern, Hongkang Zhang, Kevin Dong, Bryan D. Moyer, Christopher A. Werley
المصدر: SLAS Discovery. 25:434-446
مصطلحات موضوعية: 0303 health sciences, Chemistry, High-throughput screening, HEK 293 cells, Computational biology, Subtype selective, Biochemistry, Analytical Chemistry, 03 medical and health sciences, Electrophysiology, 0302 clinical medicine, Automated patch clamp, NAV1, Molecular Medicine, 030217 neurology & neurosurgery, 030304 developmental biology, Biotechnology
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::b158bb79b66d537a5d39c6d8bdd18fe7
https://doi.org/10.1177/2472555220914532 -
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المؤلفون: Owen B. McManus, Yalan Zhang, Leonard K. Kaczmarek, Heather McClure, David J. Gerber, Imran H. Quraishi, Siddharth Kale, Luis A. Williams, Sudhir Agrawal, Graham T. Dempsey, Yung-Chih Cheng
المصدر: FASEB J
مصطلحات موضوعية: Male, Cerebellum, Ataxia, Mutant, Motor Disorders, Protein Serine-Threonine Kinases, medicine.disease_cause, Biochemistry, Rotarod performance test, Article, Mice, Genetics, medicine, Animals, Spinocerebellar Ataxias, Molecular Biology, Spinocerebellar ataxia type-13, Mice, Knockout, Mutation, Chemistry, Wild type, Oligonucleotides, Antisense, medicine.disease, Potassium channel, Cell biology, Mice, Inbred C57BL, medicine.anatomical_structure, Shaw Potassium Channels, medicine.symptom, Biotechnology
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المؤلفون: Kurt Rasmussen, Heather E. Gorby, Christian C. Felder, Owen B. McManus, Matthew D. Hall, Samantha G. Jonson, G. Sitta Sittampalam, Amir P. Tamiz, Nathan P. Coussens
المصدر: Journal of Pharmacology and Experimental Therapeutics. 371:396-408
مصطلحات موضوعية: 0301 basic medicine, medicine.medical_specialty, Special Section on The Opioid Crisis, media_common.quotation_subject, Psychological intervention, Poison control, 03 medical and health sciences, 0302 clinical medicine, Health care, medicine, Humans, Opioid Epidemic, media_common, Pharmacology, Medical education, Government, business.industry, Public health, Addiction, Chronic pain, Opioid overdose, Congresses as Topic, Opioid-Related Disorders, medicine.disease, United States, Analgesics, Opioid, Behavior, Addictive, 030104 developmental biology, National Institutes of Health (U.S.), Molecular Medicine, Chronic Pain, business, Psychology, 030217 neurology & neurosurgery, Forecasting
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b7ee2793133b25ede846b1de64776184
https://doi.org/10.1124/jpet.119.259408 -
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المؤلفون: Gabriel B, Borja, Himali, Shroff, Hansini, Upadhyay, Pin W, Liu, Valeriya, Baru, Yung-Chih, Cheng, Owen B, McManus, Luis A, Williams, Graham T, Dempsey, Christopher A, Werley
المصدر: Methods in molecular biology (Clifton, N.J.). 2191
مصطلحات موضوعية: Neurons, Optogenetics, Calcium Channels, N-Type, Channelrhodopsins, Synapses, Animals, Humans, Calcium, Synapsins, Synaptic Transmission, Rats, Signal Transduction
URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid________::a8060881a314c8e3cd5a056924005c70
https://pubmed.ncbi.nlm.nih.gov/32865742 -
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المؤلفون: Graham T. Dempsey, Pin W. Liu, Hansini Upadhyay, Gabriel B. Borja, Christopher A. Werley, Valeriya Baru, Himali Shroff, Luis A. Williams, Yung-Chih Cheng, Owen B. McManus
المصدر: Methods in Molecular Biology ISBN: 9781071608296
مصطلحات موضوعية: 0301 basic medicine, biology, Drug discovery, Channelrhodopsin, chemistry.chemical_element, Optogenetics, Neurotransmission, Calcium, Cav2.1, 03 medical and health sciences, Electrophysiology, 030104 developmental biology, 0302 clinical medicine, chemistry, biology.protein, Synaptic signaling, Neuroscience, 030217 neurology & neurosurgery
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::dfb35627916d5e37a95faa9e16f9544b
https://doi.org/10.1007/978-1-0716-0830-2_8 -
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المؤلفون: Hongkang, Zhang, Bryan D, Moyer, Violeta, Yu, Joseph G, McGivern, Michael, Jarosh, Christopher A, Werley, Vivian C, Hecht, Ryan J, Babcock, Kevin, Dong, Graham T, Dempsey, Owen B, McManus, Chris M, Hempel
المصدر: SLAS discovery : advancing life sciences RD. 25(5)
مصطلحات موضوعية: Electrophysiology, Voltage-Gated Sodium Channel Blockers, Cricetulus, HEK293 Cells, Patch-Clamp Techniques, NAV1.7 Voltage-Gated Sodium Channel, Animals, Humans, CHO Cells, Electrophysiological Phenomena, High-Throughput Screening Assays
URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid________::0fd21ab9bf663c041689f61b02b49514
https://pubmed.ncbi.nlm.nih.gov/32292096 -
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المؤلفون: Christopher P. Austin, Rajarshi Guha, Madhu Lal-Nag, Bart Trawick, Michelle R. Arkin, Timothy L. Foley, Philip W. Iversen, Jonathan B. Baell, Thomas D.Y. Chung, Zhuyin Li, Eric W. Sayers, Neely Gal-Edd, James McGee, Owen B. McManus, Hanguan Liu, Nathan P. Coussens, Xin Xu, Viswanath Devanaryan, Marilu A. Hoeppner, Matthew D. Hall, Bruce E. Bejcek, Vance Lemmon, Kyle R. Brimacombe, Jeffrey R. Weidner, Jayme L. Dahlin, Andrew D. Napper, Steven D. Kahl, Anton Simeonov, James Inglese, Robert Pacifici, G. Sitta Sittampalam, Lisa Minor, William W. Chin, Abigail Grossman, Julie McVey, Sam Michael, Douglas S. Auld, Stacy Lathrop, Menghang Xia, Terry L. Riss, Mary Jo Wildey, Marcie A. Glicksman, Joseph V. Haas, Stephen C. Kales, O. Joseph Trask
المصدر: Clinical and Translational Science. 11:461-470
مصطلحات موضوعية: 0301 basic medicine, Extramural, Drug discovery, General Neuroscience, education, General Medicine, 01 natural sciences, Data science, General Biochemistry, Genetics and Molecular Biology, Quantitative biology, 0104 chemical sciences, 3. Good health, 010404 medicinal & biomolecular chemistry, 03 medical and health sciences, 030104 developmental biology, High-Throughput Screening Assays, General Pharmacology, Toxicology and Pharmaceutics