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المؤلفون: Lim S; Center for Cell Death and Metabolism, Mitchell Cancer Institute, University of South Alabama, Mobile, Alabama., Phillips JB; Center for Cell Death and Metabolism, Mitchell Cancer Institute, University of South Alabama, Mobile, Alabama., Madeira da Silva L; Center for Cell Death and Metabolism, Mitchell Cancer Institute, University of South Alabama, Mobile, Alabama., Zhou M; The Key Laboratory of Carcinogenesis of the Chinese Ministry of Health and The Key Laboratory of Carcinogenesis and Cancer Invasion of the Chinese Ministry of Education, Cancer Research Institute, Central South University, Changsha, Hunan, China., Fodstad O; Department of Tumor Biology, Norwegian Radium Hospital, Oslo University Hospital, University of Oslo, Oslo, Norway., Owen LB; Center for Cell Death and Metabolism, Mitchell Cancer Institute, University of South Alabama, Mobile, Alabama. mtan@health.southalabama.edu lowen@health.southalabama.edu., Tan M; Center for Cell Death and Metabolism, Mitchell Cancer Institute, University of South Alabama, Mobile, Alabama. mtan@health.southalabama.edu lowen@health.southalabama.edu.

المصدر: Cancer research [Cancer Res] 2017 Mar 15; Vol. 77 (6), pp. 1245-1249. Date of Electronic Publication: 2017 Feb 28.

نوع المنشور: Journal Article; Review; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: American Association for Cancer Research Country of Publication: United States NLM ID: 2984705R Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1538-7445 (Electronic) Linking ISSN: 00085472 NLM ISO Abbreviation: Cancer Res Subsets: MEDLINE

مواضيع طبية MeSH: Cell Cycle Checkpoints/*immunology , Immunity, Cellular/*immunology , Neoplasms/*immunology , Neoplasms/*metabolism , Tumor Microenvironment/*immunology, Animals ; Humans ; Neoplasms/pathology

المؤلفون: Kim JH; Mitchell Cancer Institute, University of South Alabama, Mobile, AL 36604, USA., Shinde DN; Ambry Genetics, Aliso Viejo, CA 92656, USA., Reijnders MRF; Department of Human Genetics, Donders Institute for Brain, Cognition, and Behaviour, Radboud University Medical Center, 6500 HB Nijmegen, the Netherlands., Hauser NS; Medical Genetics and Metabolism, Valley Children's Hospital, Madera, CA 93636, USA., Belmonte RL; Department of Biological Sciences, California State University, Chico, Chico, CA 95929, USA., Wilson GR; Department of Biological Sciences, California State University, Chico, Chico, CA 95929, USA., Bosch DGM; Department of Human Genetics, Donders Institute for Brain, Cognition, and Behaviour, Radboud University Medical Center, 6500 HB Nijmegen, the Netherlands., Bubulya PA; Department of Biological Sciences, Wright State University, Dayton, OH 45435, USA., Shashi V; Division of Medical Genetics, Department of Pediatrics, Duke University School of Medicine, Durham, NC 27710, USA., Petrovski S; Department of Medicine, University of Melbourne, Austin Hospital and Royal Melbourne Hospital, Parkville, VIC 3010, Australia; Institute for Genomic Medicine, Columbia University, New York, NY 10027, USA., Stone JK; Mitchell Cancer Institute, University of South Alabama, Mobile, AL 36604, USA., Park EY; Mitchell Cancer Institute, University of South Alabama, Mobile, AL 36604, USA., Veltman JA; Department of Human Genetics, Donders Institute for Brain, Cognition, and Behaviour, Radboud University Medical Center, 6500 HB Nijmegen, the Netherlands; Department of Clinical Genetics and School for Oncology & Developmental Biology (GROW), Maastricht University Medical Center, 6202 AZ Maastricht, the Netherlands., Sinnema M; Department of Clinical Genetics and School for Oncology & Developmental Biology (GROW), Maastricht University Medical Center, 6202 AZ Maastricht, the Netherlands., Stumpel CTRM; Department of Clinical Genetics and School for Oncology & Developmental Biology (GROW), Maastricht University Medical Center, 6202 AZ Maastricht, the Netherlands., Draaisma JM; Department of Pediatrics, Radboudumc Amalia Children's Hospital, 6500 HB Nijmegen, the Netherlands., Nicolai J; Department of Neurology, Maastricht University Medical Center, 6299 HX Maastricht, the Netherlands., Yntema HG; Department of Human Genetics, Donders Institute for Brain, Cognition, and Behaviour, Radboud University Medical Center, 6500 HB Nijmegen, the Netherlands., Lindstrom K; Division of Genetics and Metabolism, Phoenix Children's Hospital, Phoenix, AZ 85016, USA., de Vries BBA; Department of Human Genetics, Donders Institute for Brain, Cognition, and Behaviour, Radboud University Medical Center, 6500 HB Nijmegen, the Netherlands., Jewett T; Section on Medical Genetics, Department of Pediatrics, Wake Forest School of Medicine, Winston-Salem, NC 27157, USA., Santoro SL; Nationwide Children's Hospital, Columbus, OH 43205, USA; Ohio State University College of Medicine, Columbus, OH 43210, USA., Vogt J; West Midlands Regional Genetics Service, Birmingham Women's NHS Foundation Trust, Birmingham B15 2TG, UK., Bachman KK; Geisinger Medical Center, Danville, PA 17822, USA., Seeley AH; Geisinger Medical Center, Danville, PA 17822, USA., Krokosky A; Division of Genetics, Department of Pediatrics, Walter Reed National Military Medical Center, Bethesda, MD 20889, USA., Turner C; Division of Genetics, Department of Pediatrics, Walter Reed National Military Medical Center, Bethesda, MD 20889, USA., Rohena L; Division of Genetics, Department of Pediatrics, San Antonio Military Medical Center, Fort Sam Houston, TX 78234, USA; Department of Pediatrics, University of Texas Health Science Center at San Antonio, San Antonio, TX 78229, USA., Hempel M; Institute of Human Genetics, University Medical Center Hamburg-Eppendorf, 20246 Hamburg, Germany., Kortüm F; Institute of Human Genetics, University Medical Center Hamburg-Eppendorf, 20246 Hamburg, Germany., Lessel D; Institute of Human Genetics, University Medical Center Hamburg-Eppendorf, 20246 Hamburg, Germany., Neu A; Department of Pediatrics, University Medical Center Hamburg-Eppendorf, 20246 Hamburg, Germany., Strom TM; Institute of Human Genetics, Helmholtz Zentrum München, 85764 Neuherberg, Germany; Institute of Human Genetics, Technical University of Munich, 81675 Munich, Germany., Wieczorek D; Institute of Human Genetics, University Clinic Düsseldorf, Heinrich-Heine-University, 40225 Düsseldorf, Germany; Institute of Human Genetics, University Clinic Essen, University Duisburg-Essen, 45147 Essen, Germany., Bramswig N; Institute of Human Genetics, University Clinic Essen, University Duisburg-Essen, 45147 Essen, Germany., Laccone FA; Institute of Medical Genetics, Medical University of Vienna, Waehringer Strasse 10, 1090 Vienna, Austria., Behunova J; Institute of Medical Genetics, Medical University of Vienna, Waehringer Strasse 10, 1090 Vienna, Austria., Rehder H; Institute of Medical Genetics, Medical University of Vienna, Waehringer Strasse 10, 1090 Vienna, Austria., Gordon CT; Laboratory of Embryology and Genetics of Congenital Malformations, INSERM UMR 1163, Institut Imagine, 75015 Paris, France; Université Paris Descartes, Sorbonne Paris Cité, Institut Imagine, 75015 Paris, France., Rio M; Département de Génétique, Hôpital Necker-Enfants Malades, 75015 Paris, France., Romana S; Service de Cytogénétique, Hôpital Necker-Enfants Malades, 75015 Paris, France; Paris Descartes-Sorbonne Paris Cité University, Institut Imagine, 75015 Paris, France., Tang S; Ambry Genetics, Aliso Viejo, CA 92656, USA., El-Khechen D; Ambry Genetics, Aliso Viejo, CA 92656, USA., Cho MT; GeneDx Inc., 205 Perry Parkway, Gaithersburg, MD 20877, USA., McWalter K; GeneDx Inc., 205 Perry Parkway, Gaithersburg, MD 20877, USA., Douglas G; GeneDx Inc., 205 Perry Parkway, Gaithersburg, MD 20877, USA., Baskin B; GeneDx Inc., 205 Perry Parkway, Gaithersburg, MD 20877, USA., Begtrup A; GeneDx Inc., 205 Perry Parkway, Gaithersburg, MD 20877, USA., Funari T; GeneDx Inc., 205 Perry Parkway, Gaithersburg, MD 20877, USA., Schoch K; Division of Medical Genetics, Department of Pediatrics, Duke University School of Medicine, Durham, NC 27710, USA., Stegmann APA; Department of Clinical Genetics and School for Oncology & Developmental Biology (GROW), Maastricht University Medical Center, 6202 AZ Maastricht, the Netherlands., Stevens SJC; Department of Clinical Genetics and School for Oncology & Developmental Biology (GROW), Maastricht University Medical Center, 6202 AZ Maastricht, the Netherlands., Zhang DE; Moores Cancer Center, University of California, San Diego, La Jolla, CA 92093, USA; Department of Pathology, University of California, San Diego, La Jolla, CA 92093, USA; Division of Biological Sciences, University of California, San Diego, La Jolla, CA 92093, USA., Traver D; Division of Biological Sciences, University of California, San Diego, La Jolla, CA 92093, USA., Yao X; Moores Cancer Center, University of California, San Diego, La Jolla, CA 92093, USA., MacArthur DG; Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA; Analytical and Translational Genetics Unit, Massachusetts General Hospital, Boston, MA 02114, USA; Department of Medicine, Harvard Medical School, Boston, MA 02115, USA., Brunner HG; Department of Human Genetics, Donders Institute for Brain, Cognition, and Behaviour, Radboud University Medical Center, 6500 HB Nijmegen, the Netherlands; Department of Clinical Genetics and School for Oncology & Developmental Biology (GROW), Maastricht University Medical Center, 6202 AZ Maastricht, the Netherlands., Mancini GM; Department of Clinical Genetics, Erasmus University Medical Center, 3015 CN Rotterdam, the Netherlands., Myers RM; HudsonAlpha Institute for Biotechnology, Huntsville, AL 35806, USA., Owen LB; Mitchell Cancer Institute, University of South Alabama, Mobile, AL 36604, USA., Lim ST; Department of Biochemistry and Molecular Biology, College of Medicine, University of South Alabama, Mobile, AL 36688, USA., Stachura DL; Department of Biological Sciences, California State University, Chico, Chico, CA 95929, USA., Vissers LELM; Department of Human Genetics, Donders Institute for Brain, Cognition, and Behaviour, Radboud University Medical Center, 6500 HB Nijmegen, the Netherlands. Electronic address: lisenka.vissers@radboudumc.nl., Ahn EYE; Mitchell Cancer Institute, University of South Alabama, Mobile, AL 36604, USA; Department of Biochemistry and Molecular Biology, College of Medicine, University of South Alabama, Mobile, AL 36688, USA. Electronic address: eahn@health.southalabama.edu.

مؤلفون مشاركون: University of Washington Center for Mendelian Genomics, Deciphering Developmental Disorders Study; Wellcome Trust Sanger Institute, Hinxton, Cambridge CB10 1SA, UK.

المصدر: American journal of human genetics [Am J Hum Genet] 2016 Sep 01; Vol. 99 (3), pp. 711-719. Date of Electronic Publication: 2016 Aug 18.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural

بيانات الدورية: Publisher: Cell Press Country of Publication: United States NLM ID: 0370475 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1537-6605 (Electronic) Linking ISSN: 00029297 NLM ISO Abbreviation: Am J Hum Genet Subsets: MEDLINE

مواضيع طبية MeSH: Brain/*embryology , Brain/*metabolism , DNA-Binding Proteins/*genetics , Genes, Essential/*genetics , Intellectual Disability/*genetics , Minor Histocompatibility Antigens/*genetics , Mutation/*genetics , RNA Splicing/*genetics, Animals ; Brain/abnormalities ; Brain/pathology ; DNA-Binding Proteins/analysis ; DNA-Binding Proteins/metabolism ; Developmental Disabilities/genetics ; Developmental Disabilities/pathology ; Developmental Disabilities/physiopathology ; Eye Abnormalities/genetics ; Female ; Haploinsufficiency/genetics ; Head/abnormalities ; Heterozygote ; Humans ; Intellectual Disability/pathology ; Intellectual Disability/physiopathology ; Male ; Metabolic Diseases/genetics ; Metabolic Diseases/metabolism ; Minor Histocompatibility Antigens/analysis ; Minor Histocompatibility Antigens/metabolism ; Pedigree ; RNA, Messenger/analysis ; Spine/abnormalities ; Syndrome ; Zebrafish/abnormalities ; Zebrafish/embryology ; Zebrafish/genetics

المؤلفون: Tripathi K; Department of Oncologic Sciences, Mitchell Cancer Institute, University of South Alabama, Mobile, Alabama, USA., Hussein UK; Department of Oncologic Sciences, Mitchell Cancer Institute, University of South Alabama, Mobile, Alabama, USA.; Faculty of Science, Beni Suef University, Beni Suef, Egypt., Anupalli R; Department of Oncologic Sciences, Mitchell Cancer Institute, University of South Alabama, Mobile, Alabama, USA.; Department of Genetics, Osmania University, Hyderabad, India., Barnett R; Department of Oncologic Sciences, Mitchell Cancer Institute, University of South Alabama, Mobile, Alabama, USA., Bachaboina L; Department of Oncologic Sciences, Mitchell Cancer Institute, University of South Alabama, Mobile, Alabama, USA., Scalici J; Department of Oncologic Sciences, Mitchell Cancer Institute, University of South Alabama, Mobile, Alabama, USA., Rocconi RP; Department of Oncologic Sciences, Mitchell Cancer Institute, University of South Alabama, Mobile, Alabama, USA., Owen LB; Department of Oncologic Sciences, Mitchell Cancer Institute, University of South Alabama, Mobile, Alabama, USA., Piazza GA; Department of Oncologic Sciences, Mitchell Cancer Institute, University of South Alabama, Mobile, Alabama, USA., Palle K; Department of Oncologic Sciences, Mitchell Cancer Institute, University of South Alabama, Mobile, Alabama, USA.

المصدر: Oncotarget [Oncotarget] 2015 Mar 10; Vol. 6 (7), pp. 5237-52.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Impact Journals Country of Publication: United States NLM ID: 101532965 Publication Model: Print Cited Medium: Internet ISSN: 1949-2553 (Electronic) Linking ISSN: 19492553 NLM ISO Abbreviation: Oncotarget Subsets: MEDLINE

مواضيع طبية MeSH: Radiation, Ionizing*, Carcinoma, Non-Small-Cell Lung/*pathology , Cell Cycle/*drug effects , DNA Damage/*drug effects , G2 Phase Cell Cycle Checkpoints/*drug effects , Isothiocyanates/*pharmacology , Radiation-Sensitizing Agents/*pharmacology, Apoptosis/drug effects ; Apoptosis/radiation effects ; Blotting, Western ; Carcinoma, Non-Small-Cell Lung/genetics ; Carcinoma, Non-Small-Cell Lung/therapy ; Cell Cycle/radiation effects ; Cell Movement/drug effects ; Cell Movement/radiation effects ; Cell Proliferation/drug effects ; Cell Proliferation/radiation effects ; DNA Damage/radiation effects ; DNA Replication/drug effects ; DNA Replication/radiation effects ; Flow Cytometry ; Fluorescent Antibody Technique ; Food Preservatives/pharmacology ; G2 Phase Cell Cycle Checkpoints/radiation effects ; Humans ; Lung Neoplasms/genetics ; Lung Neoplasms/pathology ; Lung Neoplasms/therapy ; Tumor Cells, Cultured