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1
المؤلفون: E. Fuseau, E. Neuhart, C. Krezel, Pierre Gueret, P. L. M. van Giersbergen, S. Combe, M. Petitou
المصدر: European Journal of Clinical Pharmacology. 72:1041-1050
مصطلحات موضوعية: Adult, Male, Adolescent, Activated clotting time, Biotin, Oligosaccharides, 030204 cardiovascular system & hematology, Pharmacology, Models, Biological, Antithrombins, Young Adult, 03 medical and health sciences, 0302 clinical medicine, Thrombin, Double-Blind Method, Pharmacokinetics, medicine, Humans, Pharmacology (medical), Blood coagulation test, First-in-man study, medicine.diagnostic_test, Chemistry, General Medicine, Middle Aged, 030220 oncology & carcinogenesis, Pharmacodynamics, Factor Xa, Blood Coagulation Tests, Ecarin clotting time, medicine.drug, Partial thromboplastin time
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2
المؤلفون: M. Petitou, E. Fuseau, P. L. M. van Giersbergen, E. Neuhart, C. Krezel, Pierre Gueret
المصدر: Journal of Thrombosis and Haemostasis. 12:24-33
مصطلحات موضوعية: Male, Prothrombin time, medicine.diagnostic_test, business.industry, Activated clotting time, Anticoagulants, Oligosaccharides, Hematology, Thrombin time, Pharmacology, Placebos, Double-Blind Method, Pharmacokinetics, Direct thrombin inhibitor, Pharmacodynamics, medicine, Humans, Drug Interactions, Ecarin clotting time, business, Platelet Aggregation Inhibitors, Half-Life, Partial thromboplastin time
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3
المؤلفون: P. L. M. Van Giersbergen, Alexander Treiber, J. Dingemanse
المصدر: Int. Journal of Clinical Pharmacology and Therapeutics. 47:169-177
مصطلحات موضوعية: Adult, Male, medicine.medical_specialty, Endothelin A Receptor Antagonists, Metabolic Clearance Rate, Pyridines, Tetrazoles, Urine, In Vitro Techniques, Biology, Pharmacology, Dioxanes, Excretion, Feces, Cytochrome P-450 Enzyme System, Pharmacokinetics, In vivo, Internal medicine, medicine, Cytochrome P-450 Enzyme Inhibitors, Humans, Tissue Distribution, Pharmacology (medical), Infusions, Intravenous, Chromatography, High Pressure Liquid, Sulfonamides, Endothelin receptor antagonist, Half-life, Blood Proteins, Middle Aged, Receptor, Endothelin A, Blood proteins, Isoenzymes, Pyrimidines, Endocrinology, Half-Life, Protein Binding
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::71e3e78c7e978a98874c91c18803ed7b
https://doi.org/10.5414/cpp47169 -
4Inhibitory and Inductive Effects of Rifampin on the Pharmacokinetics of Bosentan in Healthy Subjects
المصدر: Clinical Pharmacology & Therapeutics. 81:414-419
مصطلحات موضوعية: Adult, Male, medicine.medical_specialty, Pharmacology, Mass Spectrometry, Cytochrome P-450 Enzyme System, Pharmacokinetics, Internal medicine, polycyclic compounds, medicine, Cytochrome P-450 CYP3A, Humans, Drug Interactions, Pharmacology (medical), Antibiotics, Antitubercular, Antihypertensive Agents, Chromatography, High Pressure Liquid, Cytochrome P-450 CYP2C9, Antibacterial agent, Sulfonamides, Cross-Over Studies, Protein synthesis inhibitor, business.industry, Antagonist, Rifamycin, Bosentan, Middle Aged, respiratory tract diseases, Endocrinology, Area Under Curve, Microsomes, Liver, Aryl Hydrocarbon Hydroxylases, Rifampin, Endothelin receptor, business, Algorithms, Rifampicin, Half-Life, medicine.drug
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5
المصدر: Naunyn-Schmiedeberg's Archives of Pharmacology. 345:51-56
مصطلحات موضوعية: Male, medicine.medical_specialty, Neurokinin A, Molecular Sequence Data, Urinary Bladder, Neuropeptide, Hamster, Stimulation, Phosphatidylinositols, chemistry.chemical_compound, Cricetinae, Tachykinins, Internal medicine, medicine, Animals, Amino Acid Sequence, Receptor, Receptors, Tachykinin, Neuropeptide K, Pharmacology, Mesocricetus, biology, Neuropeptides, Muscle, Smooth, General Medicine, Smooth muscle contraction, respiratory system, biology.organism_classification, Peptide Fragments, Receptors, Neurotransmitter, Endocrinology, chemistry, Muscle Contraction
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6
المصدر: Annals of the New York Academy of Sciences. 632:370-373
مصطلحات موضوعية: medicine.medical_specialty, Neurokinin A, Urinary Bladder, Urology, Hamster, Binding, Competitive, General Biochemistry, Genetics and Molecular Biology, Iodine Radioisotopes, chemistry.chemical_compound, History and Philosophy of Science, Cricetinae, medicine, Animals, Urinary bladder, General Neuroscience, Cell Membrane, Membrane Proteins, Receptors, Neurokinin-2, Molecular biology, Receptors, Neurotransmitter, Molecular Weight, medicine.anatomical_structure, Membrane, chemistry, Autoradiography
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7
المؤلفون: W. De Jong, H. De Lang, P. L. M. Van Giersbergen
المصدر: Canadian Journal of Physiology and Pharmacology. 69:327-333
مصطلحات موضوعية: Narcotics, Bradycardia, endocrine system, medicine.medical_specialty, Physiology, Neuropeptide, Hemodynamics, Blood Pressure, Dynorphin, Dynorphins, chemistry.chemical_compound, Heart Rate, Physiology (medical), Internal medicine, Heart rate, medicine, Animals, Anesthesia, Injections, Intraventricular, Pharmacology, beta-Endorphin, Dynorphin A, Rats, Inbred Strains, General Medicine, Naltrexone, Peptide Fragments, Rats, Endocrinology, Blood pressure, chemistry, medicine.symptom, hormones, hormone substitutes, and hormone antagonists
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d26b9a2df8162ac926c833985388751
https://doi.org/10.1139/y91-050 -
8
المؤلفون: P. L. M. Van Giersbergen, Henry I. Yamamura, Alden K. Henderson, S. A. Shatzer, Josephine Lai, Shigetada Nakanishi, Stephen H. Buck
المصدر: Proceedings of the National Academy of Sciences. 88:1661-1665
مصطلحات موضوعية: Urinary Bladder, Hamster, Substance P, Biology, Transfection, Binding, Competitive, Cell Line, chemistry.chemical_compound, Cricetinae, Tachykinins, medicine, Animals, Fibroblast, Receptor, Receptors, Tachykinin, Neuropeptide K, Multidisciplinary, Fibroblasts, Molecular biology, Receptors, Neurotransmitter, Kinetics, medicine.anatomical_structure, chemistry, Biochemistry, Gastric Mucosa, Cell culture, Cattle, Neurokinin A, Research Article
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::96fd6d9392301db6fdc6bf34bde68319
https://doi.org/10.1073/pnas.88.5.1661 -
9
المؤلفون: S. Weidauer, F. Ringel, P. L. M. Van Giersbergen, Peter Schmiedek, B. Meyer, Claudius Thomé, V. Breu, Jasper Dingemanse, Peter Vajkoczy, Andreas Raabe
المصدر: Acta Neurochirurgica Supplement ISBN: 9783211757178
مصطلحات موضوعية: Pharmacokinetics, business.industry, Endothelin receptor antagonist, Anesthesia, Healthy subjects, Medicine, In patient, Subarachnoid haemorrhage, business, Body weight, Endothelin 1, CLAZOSENTAN
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::bd675db648ca3575098ec45b90cb5b98
https://doi.org/10.1007/978-3-211-75718-5_24 -
10
المؤلفون: P. L. M. Van Giersbergen, Jasper Dingemanse
المصدر: Acta Neurochirurgica Supplement ISBN: 9783211757178
مصطلحات موضوعية: genetic structures, business.industry, Endothelin receptor antagonist, Healthy subjects, Pharmacology, Endothelin 1, CLAZOSENTAN, Pharmacokinetics, Tolerability, Anesthesia, Pharmacodynamics, Medicine, business, Nimodipine, medicine.drug
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::8c1bd3c28cd84f49ae03a1c2fe197215
https://doi.org/10.1007/978-3-211-75718-5_25