المؤلفون: Al-Aqtash R; Department of Pharmaceutical Sciences, University of Tennessee Health Science Center, Memphis, TN, USA., Collier DM; Department of Pharmaceutical Sciences, University of Tennessee Health Science Center, Memphis, TN, USA.

المصدر: Channels (Austin, Tex.) [Channels (Austin)] 2024 Dec; Vol. 18 (1), pp. 2355150. Date of Electronic Publication: 2024 May 19.

نوع المنشور: Journal Article; Review

بيانات الدورية: Publisher: Taylor & Francis Country of Publication: United States NLM ID: 101321614 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1933-6969 (Electronic) Linking ISSN: 19336950 NLM ISO Abbreviation: Channels (Austin) Subsets: MEDLINE

مواضيع طبية MeSH: Purinergic P2X Receptor Agonists*/pharmacology , Receptors, Purinergic P2X7*/chemistry , Receptors, Purinergic P2X7*/metabolism, Animals ; Humans ; Adenosine Triphosphate/metabolism ; Purinergic P2X Receptor Antagonists/pharmacology

المؤلفون: Soni S; Department of Pharmacology, SPP School of Pharmacy & Technology Management, SVKM's NMIMS, V.L. Mehta Road, Vile Parle (W), Mumbai, 400056, India., Lukhey MS; Department of Pharmacology, SPP School of Pharmacy & Technology Management, SVKM's NMIMS, V.L. Mehta Road, Vile Parle (W), Mumbai, 400056, India., Thawkar BS; Department of Pharmacology, Bharati Vidyapeeth's College of Pharmacy, CBD Belapur, Navi Mumbai, Maharashtra, 400614, India., Chintamaneni M; Department of Pharmacology, SPP School of Pharmacy & Technology Management, SVKM's NMIMS, V.L. Mehta Road, Vile Parle (W), Mumbai, 400056, India., Kaur G; Department of Pharmacology, SPP School of Pharmacy & Technology Management, SVKM's NMIMS, V.L. Mehta Road, Vile Parle (W), Mumbai, 400056, India. ginpreet.aneja@gmail.com., Joshi H; School of Biotechnology, Jawaharlal Nehru University, New Delhi, 110067, India., Ramniwas S; University Centre for Research and Development, University Institute of Pharmaceutical Sciences, Chandigarh University, Gharuan, Mohali, 140413, India., Tuli HS; Department of Biotechnology, Maharishi Markandeshwar Engineering College, Maharishi Markandeshwar (Deemed to Be University), Mullana-Ambala, 133207, India. hardeep.biotech@gmail.com.

المصدر: Naunyn-Schmiedeberg's archives of pharmacology [Naunyn Schmiedebergs Arch Pharmacol] 2024 Jul; Vol. 397 (7), pp. 4643-4656. Date of Electronic Publication: 2024 Feb 13.

نوع المنشور: Journal Article; Review

بيانات الدورية: Publisher: Springer Verlag Country of Publication: Germany NLM ID: 0326264 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1432-1912 (Electronic) Linking ISSN: 00281298 NLM ISO Abbreviation: Naunyn Schmiedebergs Arch Pharmacol Subsets: MEDLINE

مواضيع طبية MeSH: Patents as Topic* , Receptors, Purinergic P2X7*/metabolism , Purinergic P2X Receptor Antagonists*/therapeutic use , Purinergic P2X Receptor Antagonists*/pharmacology , Neuroinflammatory Diseases*/drug therapy, Humans ; Animals

المؤلفون: Liu Z; Children's Hospital Affiliated to Zhengzhou University, Zhengzhou University, Zhengzhou 450018, China., Liu W; School of Pharmaceutical Sciences, Zhengzhou University, Zhengzhou 450001, China., Han M; School of Pharmaceutical Sciences, Zhengzhou University, Zhengzhou 450001, China., Wang M; Children's Hospital Affiliated to Zhengzhou University, Zhengzhou University, Zhengzhou 450018, China., Li Y; School of Pharmaceutical Sciences, Zhengzhou University, Zhengzhou 450001, China. Electronic address: 13526737908@163.com., Yao Y; School of Pharmaceutical Sciences, Zhengzhou University, Zhengzhou 450001, China; Pingyuan Laboratory (Zhengzhou University), Zhengzhou 450001, China; Key Laboratory of Advanced Drug Preparation Technologies, Ministry of Education, Zhengzhou University, Zhengzhou 450001, China. Electronic address: yongfangyao@zzu.edu.cn., Duan Y; Children's Hospital Affiliated to Zhengzhou University, Zhengzhou University, Zhengzhou 450018, China; Henan International Joint Laboratory of Prevention and Treatment of Pediatric Diseases, Children's Hospital Affiliated to Zhengzhou University, Zhengzhou University, Zhengzhou 450018, China; Henan Neurodevelopment Engineering Research Center for Children, Children's Hospital Affiliated to Zhengzhou University, Zhengzhou University, Zhengzhou 450018, China. Electronic address: duanyongtao860409@163.com.

المصدر: Phytomedicine : international journal of phytotherapy and phytopharmacology [Phytomedicine] 2024 Jun; Vol. 128, pp. 155334. Date of Electronic Publication: 2023 Dec 31.

نوع المنشور: Journal Article; Review

بيانات الدورية: Publisher: Urban & Fischer Verlag Country of Publication: Germany NLM ID: 9438794 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1618-095X (Electronic) Linking ISSN: 09447113 NLM ISO Abbreviation: Phytomedicine Subsets: MEDLINE

مواضيع طبية MeSH: Receptors, Purinergic P2X7*/metabolism , Biological Products*/pharmacology , Biological Products*/chemistry , Purinergic P2X Receptor Antagonists*/pharmacology , Purinergic P2X Receptor Antagonists*/chemistry, Humans ; Signal Transduction/drug effects ; Animals

المؤلفون: Witkin JM; Laboratory of Antiepileptic Drug Discovery, Ascension St. Vincent, Indianapolis, IN, USA; Department of Neuroscience and Trauma Research, Ascension St. Vincent, Indianapolis, IN, USA; Department of Chemistry & Biochemistry, University of Wisconsin-Milwaukee, Milwaukee, WI, USA. Electronic address: witkinconsult@gmail.com., Shafique H; Duke University School of Medicine, Durham, NC, USA., Smith JL; Laboratory of Antiepileptic Drug Discovery, Ascension St. Vincent, Indianapolis, IN, USA., Cerne R; Laboratory of Antiepileptic Drug Discovery, Ascension St. Vincent, Indianapolis, IN, USA; Department of Anatomy and Cell Biology, Indiana University/Purdue University, Indianapolis, IN, USA; Faculty of Medicine, University of Ljubljana, Ljubljana, Slovenia. Electronic address: Rok_cerne@yahoo.com.

المصدر: Biochemical pharmacology [Biochem Pharmacol] 2024 Apr; Vol. 222, pp. 116046. Date of Electronic Publication: 2024 Feb 08.

نوع المنشور: Journal Article; Review

بيانات الدورية: Publisher: Elsevier Science Country of Publication: England NLM ID: 0101032 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-2968 (Electronic) Linking ISSN: 00062952 NLM ISO Abbreviation: Biochem Pharmacol Subsets: MEDLINE

مواضيع طبية MeSH: Purinergic P2X Receptor Antagonists*/pharmacology , Purinergic P2X Receptor Antagonists*/therapeutic use , Epilepsy*/drug therapy, Humans ; Pain ; Receptors, Purinergic P2X4 ; Seizures/drug therapy ; Receptors, Purinergic P2X3 ; Adenosine Triphosphate/metabolism

المؤلفون: Xie Y; Department of Neurology, Tianjin Nankai Hospital, Tianjin Medical University, Tianjin, 300052, China.; Department of Neurology, Tianjin Neurological Institute, Tianjin Medical University General Hospital, Tianjin, 300052, China., Han R; Department of Neurology, Tianjin Neurological Institute, Tianjin Medical University General Hospital, Tianjin, 300052, China., Li Y; Department of Neurology, Tianjin Neurological Institute, Tianjin Medical University General Hospital, Tianjin, 300052, China., Li W; Department of Neurology, Tianjin Nankai Hospital, Tianjin Medical University, Tianjin, 300052, China.; Department of Neurology, Tianjin Neurological Institute, Tianjin Medical University General Hospital, Tianjin, 300052, China., Zhang S; Department of Urology, Tianjin Institute of Urology, The Second Hospital of Tianjin Medical University, Tianjin, 300102, China., Wu Y; Department of Neurology, Tianjin Nankai Hospital, Tianjin Medical University, Tianjin, 300052, China., Zhao Y; Department of Neurology, Tianjin Neurological Institute, Tianjin Medical University General Hospital, Tianjin, 300052, China., Liu R; Department of Neurology, Tianjin Neurological Institute, Tianjin Medical University General Hospital, Tianjin, 300052, China., Wu J; Department of Neurology, Tianjin Neurological Institute, Tianjin Medical University General Hospital, Tianjin, 300052, China., Jiang W; Department of Neurology, Tianjin Neurological Institute, Tianjin Medical University General Hospital, Tianjin, 300052, China. jiangwei.med@gmail.com.; Department of Radiology, The Third Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan, China. jiangwei.med@gmail.com., Chen X; Department of Neurology, Tianjin Nankai Hospital, Tianjin Medical University, Tianjin, 300052, China. chyjutj@163.com.

المصدر: Journal of neuroinflammation [J Neuroinflammation] 2024 Mar 25; Vol. 21 (1), pp. 73. Date of Electronic Publication: 2024 Mar 25.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: BioMed Central Country of Publication: England NLM ID: 101222974 Publication Model: Electronic Cited Medium: Internet ISSN: 1742-2094 (Electronic) Linking ISSN: 17422094 NLM ISO Abbreviation: J Neuroinflammation Subsets: MEDLINE

مواضيع طبية MeSH: Guillain-Barre Syndrome*/drug therapy , Neuritis, Autoimmune, Experimental* , Purinergic P2X Receptor Antagonists*/pharmacology , Purinergic P2X Receptor Antagonists*/therapeutic use, Animals ; Humans ; Rats ; CD8-Positive T-Lymphocytes ; Cell Differentiation/drug effects ; Inflammasomes/drug effects ; Inflammasomes/metabolism ; NLR Family, Pyrin Domain-Containing 3 Protein/metabolism ; Sciatic Nerve/metabolism ; Th17 Cells/drug effects ; Th17 Cells/metabolism ; Th1 Cells/drug effects ; Th1 Cells/metabolism

المؤلفون: Iqbal J; Institute of Intelligent Machines, Hefei Institutes of Physical Science, Chinese Academy of Sciences, Hefei, China.; Centre for Advanced Drug Research, COMSATS University Islamabad, Abbottabad, Pakistan., Bano S; Centre for Advanced Drug Research, COMSATS University Islamabad, Abbottabad, Pakistan., Khan IA; Centre for Advanced Drug Research, COMSATS University Islamabad, Abbottabad, Pakistan., Huang Q; Institute of Intelligent Machines, Hefei Institutes of Physical Science, Chinese Academy of Sciences, Hefei, China.

المصدر: Expert opinion on therapeutic patents [Expert Opin Ther Pat] 2024 Apr; Vol. 34 (4), pp. 263-271. Date of Electronic Publication: 2024 Jun 11.

نوع المنشور: Journal Article; Review

بيانات الدورية: Publisher: Informa Healthcare Country of Publication: England NLM ID: 9516419 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1744-7674 (Electronic) Linking ISSN: 13543776 NLM ISO Abbreviation: Expert Opin Ther Pat Subsets: MEDLINE

مواضيع طبية MeSH: Patents as Topic* , Receptors, Purinergic P2X7*/metabolism , Receptors, Purinergic P2X7*/drug effects , Purinergic P2X Receptor Antagonists*/pharmacology , Inflammation*/drug therapy , Inflammation*/physiopathology, Humans ; Animals ; Drug Development ; Anti-Inflammatory Agents/pharmacology

المؤلفون: Fan Y; Department of Clinical Pharmacology, The Second Affiliated Hospital of Anhui Medical University, No. 678 Furong Road, Hefei, 230601, China., Zhang X; Department of Clinical Pharmacology, The Second Affiliated Hospital of Anhui Medical University, No. 678 Furong Road, Hefei, 230601, China., Zhang Q; Department of Clinical Pharmacology, The Second Affiliated Hospital of Anhui Medical University, No. 678 Furong Road, Hefei, 230601, China., Zheng L; Department of Clinical Pharmacology, The Second Affiliated Hospital of Anhui Medical University, No. 678 Furong Road, Hefei, 230601, China., Zhou R; Department of Clinical Pharmacology, The Second Affiliated Hospital of Anhui Medical University, No. 678 Furong Road, Hefei, 230601, China., Sun C; Department of Clinical Pharmacology, The Second Affiliated Hospital of Anhui Medical University, No. 678 Furong Road, Hefei, 230601, China., Wang X; Jiangsu Hengrui Pharmaceuticals Co., Ltd, Shanghai, China., Song K; Jiangsu Hengrui Pharmaceuticals Co., Ltd, Shanghai, China., He Z; Jiangsu Hengrui Pharmaceuticals Co., Ltd, Shanghai, China., Wang H; Jiangsu Hengrui Pharmaceuticals Co., Ltd, Shanghai, China., Zhang Q; Department of Clinical Pharmacology, The Second Affiliated Hospital of Anhui Medical University, No. 678 Furong Road, Hefei, 230601, China. vivian8011@163.com., Hu W; Department of Clinical Pharmacology, The Second Affiliated Hospital of Anhui Medical University, No. 678 Furong Road, Hefei, 230601, China. huwei@ahmu.edu.cn.

المصدر: Clinical pharmacokinetics [Clin Pharmacokinet] 2024 Mar; Vol. 63 (3), pp. 293-302. Date of Electronic Publication: 2024 Jan 10.

نوع المنشور: Randomized Controlled Trial; Clinical Trial, Phase I; Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Country of Publication: Switzerland NLM ID: 7606849 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1179-1926 (Electronic) Linking ISSN: 03125963 NLM ISO Abbreviation: Clin Pharmacokinet Subsets: MEDLINE

مواضيع طبية MeSH: Purinergic P2X Receptor Antagonists*/adverse effects , Dysgeusia*, Male ; Humans ; Healthy Volunteers ; Dose-Response Relationship, Drug ; Area Under Curve ; Double-Blind Method

المؤلفون: Shah Q; Centre for Advanced Drug Research, COMSATS University Islamabad, Abbottabad Campus, Abbottabad 22060, Pakistan; Department of Pharmacy, COMSATS University Islamabad, Abbottabad Campus, Abbottabad 22060, Pakistan., Hussain Z; Centre for Advanced Drug Research, COMSATS University Islamabad, Abbottabad Campus, Abbottabad 22060, Pakistan., Ahmad Khan B; Department of Chemistry, University of Azad Jammu and Kashmir, Muzaffarabad 13100, Pakistan., Jacobson KA; Molecular Recognition Section, Laboratory of Bioorganic Chemistry, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda MD 20892, USA. Electronic address: kennethj@niddk.nih.gov., Iqbal J; Centre for Advanced Drug Research, COMSATS University Islamabad, Abbottabad Campus, Abbottabad 22060, Pakistan; Department of Pharmacy, COMSATS University Islamabad, Abbottabad Campus, Abbottabad 22060, Pakistan. Electronic address: drjamshed@cuiatd.edu.pk.

المصدر: Bioorganic chemistry [Bioorg Chem] 2023 Nov; Vol. 140, pp. 106796. Date of Electronic Publication: 2023 Sep 01.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Intramural

بيانات الدورية: Publisher: Elsevier Country of Publication: United States NLM ID: 1303703 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1090-2120 (Electronic) Linking ISSN: 00452068 NLM ISO Abbreviation: Bioorg Chem Subsets: MEDLINE

مواضيع طبية MeSH: Astrocytoma* , Hydroxyquinolines* , Quinolines*/chemical synthesis , Quinolines*/pharmacology , Purinergic P2X Receptor Antagonists*/chemical synthesis , Purinergic P2X Receptor Antagonists*/pharmacology, Humans ; Apoptosis ; Receptors, Purinergic P2X7

المؤلفون: Reif S; Clinical Pharmacology, Bayer AG Research and Development, Pharmaceuticals, Müllerstraße 178, 13353, Berlin, Germany. stefanie.reif@bayer.com., Schultze-Mosgau MH; Clinical Pharmacology, Bayer AG Research and Development, Pharmaceuticals, Müllerstraße 178, 13353, Berlin, Germany., Engelen A; Bayer AG Research and Development, Pharmaceuticals, Wuppertal, Germany., Piel I; Bayer AG Research and Development, Pharmaceuticals, Wuppertal, Germany., Denner K; Clinical Pharmacology, Bayer AG Research and Development, Pharmaceuticals, Müllerstraße 178, 13353, Berlin, Germany., Roffel A; ICON Plc (Formerly PRA Health Sciences), Van Swietenlaan 6, 9728 NZ, Groningen, The Netherlands., Tiessen R; ICON Plc (Formerly PRA Health Sciences), Van Swietenlaan 6, 9728 NZ, Groningen, The Netherlands., Klein S; Clinical Pharmacology, Bayer AG Research and Development, Pharmaceuticals, Müllerstraße 178, 13353, Berlin, Germany., Francke K; Clinical Pharmacology, Bayer AG Research and Development, Pharmaceuticals, Müllerstraße 178, 13353, Berlin, Germany., Rottmann A; Clinical Pharmacology, Bayer AG Research and Development, Pharmaceuticals, Müllerstraße 178, 13353, Berlin, Germany.

المصدر: European journal of drug metabolism and pharmacokinetics [Eur J Drug Metab Pharmacokinet] 2024 Jan; Vol. 49 (1), pp. 71-85. Date of Electronic Publication: 2023 Dec 03.

نوع المنشور: Controlled Clinical Trial; Clinical Trial, Phase I; Journal Article

بيانات الدورية: Publisher: Springer France Country of Publication: France NLM ID: 7608491 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2107-0180 (Electronic) Linking ISSN: 03787966 NLM ISO Abbreviation: Eur J Drug Metab Pharmacokinet Subsets: MEDLINE

مواضيع طبية MeSH: Purinergic P2X Receptor Antagonists* , Metabolic Networks and Pathways*, Humans ; Male ; Chromatography, High Pressure Liquid/methods ; Mass Spectrometry ; Feces/chemistry ; Administration, Oral ; Volunteers ; Healthy Volunteers

المؤلفون: Ramadan A; Faculty of Medicine, South Valley University, Qena, Egypt. Electronic address: alaaramadan251@gmail.com., El-Samahy M; Faculty of Medicine, Zagazig University, Zagazig, Egypt., Elrosasy A; Faculty of Medicine, Cairo University, Cairo, Egypt., Al-Tawil M; Faculty of Medicine, Al-Quds University, Jerusalem, Palestine., Abdelaziz A; Faculty of Medicine, Al-Azhar University, Cairo, Egypt., Soliman MA; Faculty of Medicine, Cairo University, Cairo, Egypt., Abouzid M; Department of Physical Pharmacy and Pharmacokinetics, Faculty of Pharmacy, Poznan University of Medical Sciences, Poznan, Poland; Doctoral School, Poznan University of Medical Sciences, Poznan, Poland.

المصدر: Pulmonary pharmacology & therapeutics [Pulm Pharmacol Ther] 2023 Dec; Vol. 83, pp. 102252. Date of Electronic Publication: 2023 Sep 09.

نوع المنشور: Meta-Analysis; Systematic Review; Journal Article; Review

بيانات الدورية: Publisher: Academic Press Country of Publication: England NLM ID: 9715279 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1522-9629 (Electronic) Linking ISSN: 10945539 NLM ISO Abbreviation: Pulm Pharmacol Ther Subsets: MEDLINE

مواضيع طبية MeSH: Purinergic P2X Receptor Antagonists*/adverse effects , Ageusia*/chemically induced , Ageusia*/drug therapy, Humans ; Dysgeusia/chemically induced ; Dysgeusia/drug therapy ; Chronic Disease ; Randomized Controlled Trials as Topic ; Cough/drug therapy