المؤلفون: Pingping Luo, Rui Zhang, Qian Yu, George L. Tipoe, Ming Zheng, Xiaoming Sun, Yingxia Liu, Jia Xiao, Wei Li, Hong Zhang

المصدر: Acta Pharmaceutica Sinica. B
Acta Pharmaceutica Sinica B, Vol 11, Iss 3, Pp 668-679 (2021)

مصطلحات موضوعية: Alcoholic liver disease, INSR, insulin receptor, TCF/LEF, T-cell factor/lymphoid enhancer factor, AST, aspartate aminotransferase, Pharmacology, TSA, thermal shift assay, 0302 clinical medicine, WAT, white adipose tissues, HSL, hormone sensitive lipase, FFA, free fatty acids, MTT, 3-(4,5-dimethyl-thiazol-2-yl)-2,5-diphenyl-tetrazolium bromide, General Pharmacology, Toxicology and Pharmaceutics, NF-κB, nuclear factor kappa B, RER, respiratory exchange ratio, 0303 health sciences, LRP6, low-density lipoprotein receptor related protein 6, TNF, tumor necrosis factor, NAS, NAFLD activity score, biology, TG, triglyceride, Chemistry, NIAAA, National Institute on Alcohol Abuse and Alcoholism, Liver cell, CYP2E1, cytochrome P450 2E1, 030220 oncology & carcinogenesis, LDLR, low-density lipoprotein receptor, NRF2, nuclear factor erythroid 2-related factor 2, IRS, insulin receptor substrate, GTT, glucose tolerance test, Original Article, medicine.symptom, Safety, IRTK, insulin receptor tyrosine kinase, GSK3β, glycogen synthase kinase 3 beta, NAFLD, non-alcoholic fatty liver disease, ALD, alcoholic liver disease, SREBP-1c, sterol regulatory element-binding protein 1c, Inflammation, SPR, surface plasmon resonance, AMPK, adenosine 5′-monophosphate (AMP)-activated protein kinase, SAMC, S-allylmercaptocysteine, 03 medical and health sciences, ADIPOQ, adiponectin, Insulin resistance, ORF, open reading frame, PA, palmitate acid, ALT, alanine aminotransferase, medicine, CPT1, carnitine palmitoyltransferase I, IRS-1, GRB14, growth factor receptor-bound protein 14, Protein kinase B, 030304 developmental biology, ATGL, adipose triglyceride lipase, PPARα, peroxisome proliferator-activated receptor alpha, AKT, lcsh:RM1-950, ALDH2, aldehyde dehydrogenase 2, GSK3β, Lipid metabolism, medicine.disease, S-Allylmercaptocysteine, WT, wild-type, IL, interleukin, TC, total cholesterol, Insulin receptor, FDA, U.S. Food and Drug Administration, lcsh:Therapeutics. Pharmacology, biology.protein, NAC, N-acetyl-cysteine, Steatosis, IGF-1, insulin-like growth factors-1

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f71348640a2921fa24860e2b42b33f51
http://europepmc.org/articles/PMC7982498

المؤلفون: Moshe Arditi, Roberta A. Gottlieb, Jon Sin, Ozlem Tufanli, Ebru Erbay, Prediman K. Shah, Asli D. Yildirim, Zehra Veli, Umut Inci Onat, Begüm Kocatürk, Kenichi Shimada, Ismail Çimen, Shuang Chen, Syed M. Hamid

المساهمون: Onat, Umut I., Yıldırım, Aslı D., Tufanlı, Özlem, Çimen, İsmail, Kocatürk, Begüm, Veli, Zehra, Erbay, Ebru

المصدر: Journal of the American College of Cardiology

مصطلحات موضوعية: ATF4, activating transcription factor 4, Metabolic inflammation, interleukin-1β, Inflammasomes, Eukaryotic Initiation Factor-2, Interleukin-1beta, CCL2, C-D motif ligand-2, 030204 cardiovascular system & hematology, Endoplasmic Reticulum, PA, palmitate, siRNA, silencer RNA, Inflammasome, Mice, UPR, unfolded protein response, 0302 clinical medicine, BMDM, bone marrow–derived macrophages, GAS, Group A Streptococcus, 030212 general & internal medicine, Phosphorylation, Dietary fats, TNF, tumor necrosis factor, CHOP, CCAT/enhancer-binding protein beta homologous protein, food and beverages, integrated stress response, Lipids, Interleukin-1β, Plaque, Atherosclerotic, metabolic inflammation, Mitochondria, Cell biology, Interleukin 1β, eIF2α, eukaryotic initiation factor 2 alpha, Inflammation Mediators, IRE1, inositol-requiring enzyme-1, Cardiology and Cardiovascular Medicine, eIF2B, eukaryotic initiation factor 2B, Signal Transduction, medicine.drug, CVD, cardiovascular disease(s), PERK, protein kinase R-like endoplasmic reticulum kinase/eIF2α kinase, SFA, saturated fatty acid, Alpha (ethology), Article, ER, endoplasmic reticulum, Integrated stress response, 03 medical and health sciences, inflammasome, Stress, Physiological, medicine, Animals, Humans, PINK1, phosphatase and tensin-induced putative kinase1, lipid-induced inflammation, LONP1, Lon protease 1, ISR, integrated stress response, Parkin, Parkinson juvenile disease protein 2, Lipid-induced inflammation, business.industry, NLRP3, Nod-like receptor family, pyrin domain-containing protein-3, Atherosclerosis, Mationmetabolic inflammation, Dietary Fats, IL, interleukin, mtROS, mitochondrial reactive oxygen species, Oxidative Stress, ASKA, ATP-analog sensitive kinase allele, business, human activities

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0580eaacd500c248ffb583c0eca1a596
https://doi.org/10.1016/j.jacc.2018.12.055

المؤلفون: Qing, Zhang, Jia, Liu, Huxinyue, Duan, Ruolan, Li, Wei, Peng, Chunjie, Wu

المصدر: Journal of Advanced Research

مصطلحات موضوعية: SMT, Samul-Tang Tang, ICAM, intercellular adhesion molecule, TrxR1, thioredoxin reductase-1, HG, high glucose, SchB, Schisandrin B, Z-Lig, Z-ligustilide, CINM, Cinnamaldehyde, PA, Palmitate, ET, endothelin, OA, Oleanolic acid, ApoE, apolipoprotein E, LWDH, Liuwei-Dihuang pill, PEITC, phenethyl isocyanate, DMY, Dihydromyricetin, 7-HMR, (−)-7(S)-hydroxymatairesinol, APV, aqueous extracts of Prunella Vulgaris, KGRE, extracts of KGR, AGE, advanced glycation end product, MA, maslinic acid, NAF, Nepeta Angustifolia, OMT, Oxymatrine, MCP-1, monocyte chemotactic protein 1, PT, Pterostilbene, HXC, Huoxue capsule, CVDs, cardiovascular diseases, Vascular endothelial cells, ECs, endothelial cells, NF-E2-Related Factor 2, CNC, Cap'n'collar, VA, Vanillic acid, Article, BITC, benzyl isothiocyanate, Molecular mechanism, FFA, Fatty Acids, ASD-IV, Astragaloside IV, KRG, Korean red ginseng, OX-LDL, oxidized low density lipoprotein, VEC, vascular endothelial cells, PI3K, phosphatidylinositol 3 kinase, PKC, protein kinase C, Humans, MCGA3, 3-O-caffeoyl-1-methylquinic acid, EXS, Xanthoceras sorbifolia, HIF-1, Hypoxia-inducible factor 1, SAL, Salidroside, ERK, extracellular regulated protein kinases, IL, interleukin, Oxidative stress, Akt, protein kinase B, Nrf2/HO-1 signaling, TXA2, Thromboxane A2, MMPs, matrix metalloproteinases, RBPC, phenolic extracts derived from rice bran, NG, naringenin, Heme Oxygenase-1, VEI, vascular endothelial injury, ADH, andrographolide, ARE, antioxidant reaction elements, US, uraemic serum, XAG, xanthoangelol, Keap1, kelch-like epichlorohydrin-related proteins, MAPKs, mitogen-activated protein kinases, Hcy, Homocysteine, NQO1, NAD(P)H: quinone oxidoreductase, SFN, sulforaphane, ASP, Angelica sinensis polysaccharide, TNF, tumor necrosis factor, PAA, Pachymic acid, eNOS, endothelial NO synthase, ASTP, Astragalus polysacharin, MAPKK, mitogen-activated protein kinase kinase, Pharmaceutical Preparations, HO-1, heme oxygenase, GPx, Glutathione peroxidase, CVRF, cardiovascular risk factors, EGCG, epigallocatechin-3-O-gallate, Herbal medicine, TCM, traditional Chinese medicine, AS, atherosclerosis, Gau A, Glaucocalyxin A, XXT, Xueshuan Xinmaining Tablet, HAMS, human anthocyanin medicated serum, GTE, Ganoderma tsugae extracts, HUVECs, human umbilical vein endothelial cells, CREB, cAMP-response element binding protein, BBR, Berberine, ROS, reactive oxygen species, SOD, superoxide dismutase, Nrf2, nuclear factor erythroid-2 related factor 2, ComputingMethodologies_COMPUTERGRAPHICS, C3G, Cyanidin-3-O-glucoside, Sal B, salvianolic acid B, Endothelial Cells, Atherosclerosis, BAECs, bovine artery endothelial cells, NF-κB, nuclear factor kappa-B, AMP, Athyrium Multidentatum, GSD Rg1, Ginsenoside Rg1, ECC, (−)-Epicatechin, PAI-1, plasminogen activator Inhibitor-1, Ang, Angiotensin, VCAM, vascular cell adhesion molecule

URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid________::9de6be7acea23fd93887832ef07452a1
https://pubmed.ncbi.nlm.nih.gov/35024180

المؤلفون: Jeffrey A. Medin, Xuefang Pan, Victoria Smutova, Bruno Larrivée, Christopher W. Cairo, Nikolaus Heveker, Anne Fougerat, Alexey V. Pshezhetsky, Tarik Issad

المساهمون: Institut des Maladies Métaboliques et Cardiovasculaires (I2MC), Université Toulouse III - Paul Sabatier (UT3), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-Institut National de la Santé et de la Recherche Médicale (INSERM), Research center, Ste-Justine Hospital Research Center, Institut Cochin (IC UM3 (UMR 8104 / U1016)), Université Paris Descartes - Paris 5 (UPD5)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), Angiogénèse embryonnaire et pathologique, Université Pierre et Marie Curie - Paris 6 (UPMC)-Collège de France (CdF)-Institut National de la Santé et de la Recherche Médicale (INSERM), Department of Medical Biophysics (MBP), University of Toronto, Division of Medical Genetics, CHU Sainte Justine [Montréal], Centre interdisciplinaire de recherche en biologie (CIRB), Labex MemoLife, École normale supérieure - Paris (ENS Paris), Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Collège de France (CdF (institution))-Ecole Superieure de Physique et de Chimie Industrielles de la Ville de Paris (ESPCI Paris), Université Paris sciences et lettres (PSL)-École normale supérieure - Paris (ENS Paris), Université Paris sciences et lettres (PSL)-Centre National de la Recherche Scientifique (CNRS)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Labex MemoLife, Université Paris sciences et lettres (PSL)-Centre National de la Recherche Scientifique (CNRS)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Pierre et Marie Curie - Paris 6 (UPMC)

المصدر: Molecular Metabolism, Vol 12, Iss, Pp 76-88 (2018)
Molecular metabolism
Molecular metabolism, Elsevier, 2018, 12, pp.76-88. ⟨10.1016/j.molmet.2018.03.017⟩
Molecular Metabolism

مصطلحات موضوعية: 0301 basic medicine, HFD, high-fat diet, medicine.medical_treatment, PNA, peanut agglutinin, IGTT, intraperitoneal glucose tolerance test, Cathepsin A, Mice, NEU1, 0302 clinical medicine, TFEB, transcription factor EB, Receptor, DANA, 2,3-dehydro-2-deoxy-N-acetylneuraminic acid, AV, adenovirus, LV, lentivrus, ComputingMilieux_MISCELLANEOUS, PA, palmitate, Ambroxol, trans-4-(2-Amino-3,5-dibromobenzylamino)cyclohexanol, biology, Chemistry, Hep G2 Cells, [SDV.MHEP.EM]Life Sciences [q-bio]/Human health and pathology/Endocrinology and metabolism, 3. Good health, Insulin signaling, Ambroxol, Liver, IR, insulin receptor, Original Article, lcsh:Internal medicine, medicine.medical_specialty, Neuraminidase, 03 medical and health sciences, Insulin resistance, Neuraminidase 1, Internal medicine, medicine, Animals, Humans, [SDV.BBM]Life Sciences [q-bio]/Biochemistry, Molecular Biology, Obesity, BRET, bioluminescence resonance energy transfer, Muscle, Skeletal, lcsh:RC31-1245, Molecular Biology, ITT, insulin tolerance test, Activator (genetics), Catabolism, NEU1, neuraminidase 1, Insulin, T2DM, type 2 diabetes mellitus, Cell Biology, medicine.disease, Receptor, Insulin, Mice, Inbred C57BL, Insulin receptor, HEK293 Cells, 030104 developmental biology, Endocrinology, biology.protein, [SDV.AEN]Life Sciences [q-bio]/Food and Nutrition, [SDV.MHEP]Life Sciences [q-bio]/Human health and pathology, 030217 neurology & neurosurgery

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d25418402ba632a1e60eeca6f9e2b09
https://doi.org/10.1016/j.molmet.2018.03.017

المؤلفون: Alexandra K. Leamy, Jamey D. Young, Robert A. Egnatchik, Masakazu Shiota, David A. Jacobson

المصدر: Molecular Metabolism

مصطلحات موضوعية: NAFLD, non-alcoholic fatty liver disease, medicine.medical_specialty, SERCA, NASH, non-alcoholic steatohepatitis, SFA, saturated fatty acid, chemistry.chemical_element, Biology, Calcium, Mitochondrion, medicine.disease_cause, PA, palmitate, Calcium in biology, PI, propidium iodide, 03 medical and health sciences, chemistry.chemical_compound, H2DCFDA, 2′,7′-dichlorodihydrofluorescein diacetate, ROS, reactive oxygen species, 0302 clinical medicine, BAPTA, Fatty liver, Internal medicine, CAC, citric acid cycle, FFA, free fatty acid, MUFA, monounsaturated fatty acid, medicine, Molecular Biology, MFA, metabolic flux analysis, 030304 developmental biology, chemistry.chemical_classification, 0303 health sciences, Reactive oxygen species, APE, atom percent enrichment, Metabolic flux analysis, Cell Biology, SERCA, sarcoplasmic-endoplasmic reticulum calcium ATPase, 3. Good health, Endocrinology, chemistry, Lipotoxicity, Oxidative stress, OA, oleate, 030220 oncology & carcinogenesis, Original Article, BSA, bovine serum albumin, GC–MS, gas chromatography–mass spectrometry, ER stress

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c8abb056af369ca34e6c97f53de9251

المؤلفون: Victoria C. Foletta, Aaron P. Russell, Kimberley J. Anderson

المصدر: FEBS Open Bio, Vol 5, Iss 1, Pp 668-681 (2015)
FEBS Open Bio

مصطلحات موضوعية: Myoblast proliferation, Mcl-1, myeloid cell leukemia 1, Cyclin D, Ckm, muscle creatine kinase, Proliferation, Apoptosis, MyoD, PA, palmitate, Biology (General), Rb, retinoblastoma, Caspase, biology, Bcl-xL, Bcl-2-like 1, musculoskeletal system, MyoD, myogenic differentiation, p27, p27 kip1, H2O2, hydrogen peroxide, Differentiation, Myh7, myosin, heavy polypeptide 7, ER stress, C2C12, tissues, Lipotoxicity, Myoblast, PKCθ, protein kinase C theta, QH301-705.5, Bcl-2, B cell leukemia/lymphoma 2, NDRG2, N-myc downstream-regulated gene 2, Bcl-xL, Caspase 3, Cdk, cyclin-dependent kinase, General Biochemistry, Genetics and Molecular Biology, ER, endoplasmic reticulum, Cyclin-dependent kinase, Acta1, skeletal muscle alpha-actin, Research article, PARP, poly (ADP-ribose) polymerase family, member, SGK1, serum- and glucocorticoid-inducible kinase 1, Myf5, myogenic factor 5, Myotube, NDRG2, Caspase, apoptosis-related cysteine peptidase, Molecular biology, Bax, Bcl-2-associated X protein, GRP78, glucose-regulated protein 78, Akt, thymoma viral proto-oncogene, Oxidative stress, biology.protein, p21, p21 waf1/cip1, MRFs, myogenic regulatory factors

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::21eeb5370754cb07c22c33e2907c5fed

المؤلفون: Zhang Q; School of Pharmacy, Chengdu University of Traditional Chinese Medicine, Chengdu 611130, PR China., Liu J; School of Pharmacy, Chengdu University of Traditional Chinese Medicine, Chengdu 611130, PR China., Duan H; School of Pharmacy, Chengdu University of Traditional Chinese Medicine, Chengdu 611130, PR China., Li R; School of Pharmacy, Chengdu University of Traditional Chinese Medicine, Chengdu 611130, PR China., Peng W; School of Pharmacy, Chengdu University of Traditional Chinese Medicine, Chengdu 611130, PR China., Wu C; School of Pharmacy, Chengdu University of Traditional Chinese Medicine, Chengdu 611130, PR China.

المصدر: Journal of advanced research [J Adv Res] 2021 Jul 06; Vol. 34, pp. 43-63. Date of Electronic Publication: 2021 Jul 06 (Print Publication: 2021).

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't; Review

بيانات الدورية: Publisher: Cairo University, production and hosting by Elsevier B. V Country of Publication: Egypt NLM ID: 101546952 Publication Model: eCollection Cited Medium: Internet ISSN: 2090-1224 (Electronic) Linking ISSN: 20901224 NLM ISO Abbreviation: J Adv Res Subsets: MEDLINE

مواضيع طبية MeSH: Atherosclerosis*/drug therapy , Pharmaceutical Preparations*, Endothelial Cells/metabolism ; Heme Oxygenase-1/metabolism ; Herbal Medicine ; Humans ; NF-E2-Related Factor 2/metabolism ; Oxidative Stress

المؤلفون: Luo P; Clinical Medicine Research Institute, the First Affiliated Hospital of Jinan University, Guangzhou 510632, China., Zheng M; Department of Interventional Surgery, the First Affiliated Hospital of Jinan University, Guangzhou 510632, China., Zhang R; Clinical Medicine Research Institute, the First Affiliated Hospital of Jinan University, Guangzhou 510632, China., Zhang H; Department of Interventional Surgery, the First Affiliated Hospital of Jinan University, Guangzhou 510632, China., Liu Y; State Key Discipline of Infectious Diseases, Department of Infectious Diseases, Shenzhen Third People's Hospital, Shenzhen 518000, China., Li W; Faculty of Pharmaceutical Sciences, Toho University, Chiba 2748510, Japan., Sun X; School of Integrative Pharmacy, Institute of Integrative Pharmaceutical Research, Guangdong Pharmaceutical University, Guangzhou 510000, China., Yu Q; School of Biomedical Sciences, Li Ka Shing Faculty of Medicine, the University of Hong Kong, Hong Kong 999077, China., Tipoe GL; School of Biomedical Sciences, Li Ka Shing Faculty of Medicine, the University of Hong Kong, Hong Kong 999077, China., Xiao J; Clinical Medicine Research Institute, the First Affiliated Hospital of Jinan University, Guangzhou 510632, China.; School of Biomedical Sciences, Li Ka Shing Faculty of Medicine, the University of Hong Kong, Hong Kong 999077, China.

المصدر: Acta pharmaceutica Sinica. B [Acta Pharm Sin B] 2021 Mar; Vol. 11 (3), pp. 668-679. Date of Electronic Publication: 2020 Nov 13.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 101600560 Publication Model: Print-Electronic Cited Medium: Print ISSN: 2211-3835 (Print) Linking ISSN: 22113835 NLM ISO Abbreviation: Acta Pharm Sin B Subsets: PubMed not MEDLINE

مصطلحات الفهرس: Acta1, skeletal muscle alpha-actin, Akt, thymoma viral proto-oncogene, Apoptosis, Bax, Bcl-2-associated X protein, Bcl-2, B cell leukemia/lymphoma 2, Bcl-xL, Bcl-2-like 1, Caspase, apoptosis-related cysteine peptidase, Cdk, cyclin-dependent kinase, Ckm, muscle creatine kinase, Differentiation, ER stress, ER, endoplasmic reticulum, GRP78, glucose-regulated protein 78, H2O2, hydrogen peroxide, Lipotoxicity, MRFs, myogenic regulatory factors, Mcl-1, myeloid cell leukemia 1, Myf5, myogenic factor 5, Myh7, myosin, heavy polypeptide 7, MyoD, myogenic differentiation, Myoblast, Myotube, NDRG2, NDRG2, N-myc downstream-regulated gene 2, Oxidative stress, PA, palmitate, PARP, poly (ADP-ribose) polymerase family, member, PKCθ, protein kinase C theta, Proliferation, Rb, retinoblastoma, SGK1, serum- and glucocorticoid-inducible kinase 1, p21, p21 waf1/cip1, p27, p27 kip1, Journal Article

URL: http://hdl.handle.net/10536/DRO/DU:30080622
https://dro.deakin.edu.au/eserv/DU:30080622/russell-ndrg2promotesmyoblast-2015.pdf
issn: 2211-5463
https://dro.deakin.edu.au/eserv/DU:30080622/russell-ndrg2promotesmyoblast-2015.pdf
http://www.dx.doi.org/10.1016/j.fob.2015.08.001
FEBS open bio

المؤلفون: Anderson KJ; Centre for Physical Activity and Nutrition Research (C-PAN), School of Exercise and Nutrition Sciences, Faculty of Health, Deakin University, Melbourne, Australia., Russell AP; Centre for Physical Activity and Nutrition Research (C-PAN), School of Exercise and Nutrition Sciences, Faculty of Health, Deakin University, Melbourne, Australia., Foletta VC; Centre for Physical Activity and Nutrition Research (C-PAN), School of Exercise and Nutrition Sciences, Faculty of Health, Deakin University, Melbourne, Australia.

المصدر: FEBS open bio [FEBS Open Bio] 2015 Aug 07; Vol. 5, pp. 668-81. Date of Electronic Publication: 2015 Aug 07 (Print Publication: 2015).

نوع المنشور: Journal Article

بيانات الدورية: Publisher: John Wiley & Sons Ltd Country of Publication: England NLM ID: 101580716 Publication Model: eCollection Cited Medium: Print ISSN: 2211-5463 (Print) Linking ISSN: 22115463 NLM ISO Abbreviation: FEBS Open Bio Subsets: PubMed not MEDLINE