المؤلفون: Alexey A. Martyanov, Anna E. Boldova, Maria G. Stepanyan, Olga I. An, Alexander S. Gur'ev, Darya V. Kassina, Alexey Y. Volkov, Alexandr V. Balatskiy, Andrei A. Butylin, Sergei S. Karamzin, Elena V. Filimonova, Sergei V. Tsarenko, Sergei A. Roumiantsev, Alexander G. Rumyantsev, Mikhail A. Panteleev, Fazoil I. Ataullakhanov, Anastasia N. Sveshnikova

المصدر: Thrombosis Research

مصطلحات موضوعية: Blood Platelets, ECMO, Extracorporeal Membrane Oxygenation, VWF, Von Willebrand Factor, Severity of Illness Index, Article, ICU, Intensive Care Unit, MFI, Mean Fluorescence Intensity, TPO, Thrombopoietin, Humans, IL, Interleukin, NET, Neutrophil Extracellular TRAP, PCR, Polymerase Chain Reaction, Flow cytometry, LMWH, Low Molecular Weight Heparin, COVID-19, Coronavirus disease 2019, PPP, Platelet Poor Plasma, SARS-CoV-2, Anticoagulants, COVID-19, ARDS, Acute Respiratory Distress Syndrome, Thrombosis, Hematology, Extracellular traps, Heparin, Low-Molecular-Weight, GPIb, Glycoprotein Ib, TRAP, Thrombin Receptor Activating Peptide, LPS, Lipopolysaccharides, Thrombocytopenia, PAR, Protease Activated Receptor, COVID-19 Drug Treatment, ACE-2, Angiotensin Converting Enzyme 2, PRP, Platelet Rich Plasma, GPVI, Glycoprotein VI, ADAM-17, A Disintegrin and Metalloprotease 17, RNA, Viral, PMA, Phorbol Myristate Acetate, CLEC-2, C-type lectin-like receptor 2, BSA, Bovine Serum Albumin, MAPK, Mitogen-activated Protein Kinase, FSC, Forward Light Scattering

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::09171bc1034192e225b611aa23b08352
https://pubmed.ncbi.nlm.nih.gov/35066204

المؤلفون: Mohamed G. Ewees, Asmaa M.A. Bayoumi, Ali Ahmed Abo-Saif, Mohamed S. Abdel-Bakky, Waleed M Altowayan, Khalid Saad Alharbi, Basim A.S. Messiha

المصدر: Journal of Advanced Research
Journal of Advanced Research, Vol 31, Iss, Pp 127-136 (2021)

مصطلحات موضوعية: 0301 basic medicine, Male, Medicine (General), Science (General), Pt, Prothrombin time, Pharmaceutical Science, Cr, creatinine, Apoptosis, GSH, Reduced Glutathion, Pharmacology, medicine.disease_cause, Kidney, SOD, Superoxide dismutase, Blood Urea Nitrogen, Q1-390, 0302 clinical medicine, Neoplasms, Multidisciplinary, biology, Caspase 3, Thrombin, pERK1/2, PAR2, female genital diseases and pregnancy complications, Dabigatran, medicine.anatomical_structure, Dab, Dabigatran, Crcl, Creatinine clerance, 030220 oncology & carcinogenesis, Kidney Diseases, INR, International normalized ratio, KIM-1, kidney injury molecule-1, medicine.drug, BUN, Blood urea nitrogen, inorganic chemicals, MAP Kinase Signaling System, Down-Regulation, Fibrin, Antithrombins, Nephrotoxicity, 03 medical and health sciences, Tissue factor, R5-920, CDDP, Cisplatin, medicine, Animals, neoplasms, ComputingMethodologies_COMPUTERGRAPHICS, Cisplatin, business.industry, H&E, Hematoxylin–Eosin, Ptt, Partial thromboplastin time, Rats, FXa, activated form of Factor X, Oxidative Stress, 030104 developmental biology, Direct thrombin inhibitor, biology.protein, TF, Tissue factor, PAR, protease-activated receptor, Tumor Suppressor Protein p53, business, Oxidative stress, ROS, Reactive oxygen species

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::77c352990f849092c81ea73fddb3c78f
https://pubmed.ncbi.nlm.nih.gov/34194837

المؤلفون: Sedehizade, Fariba, von Klot, Christoph, Hanck, Theodor, Reiser, Georg

المصدر: Neurochemical Research. October 2005 30(10):1319-1330

المؤلفون: Francesco, Franchi, Fabiana, Rollini, Victor, Kairouz, Jose, Rivas Rios, Andrea, Rivas, Malhar, Agarwal, Maryuri, Briceno, Mustafa, Wali, Ahmed, Nawaz, Gabriel, Silva, Zubair, Shaikh, Naji, Maaliki, Latonya, Been, Jason, Piraino, Andres M, Pineda, Siva, Suryadevara, Daniel, Soffer, Martin M, Zenni, Lisa K, Jennings, Theodore A, Bass, Dominick J, Angiolillo

المصدر: JACC: Basic to Translational Science

مصطلحات موضوعية: TXB2, thromboxane B2, vorapaxar, o.d., once daily, CLINICAL RESEARCH, CAT, collagen-related peptide + adenosine diphosphate + thrombin receptor activating peptide, MPA, maximum platelet aggregation, dual antiplatelet therapy, thrombin, ADP, adenosine diphosphate, CI, confidence interval, COX, cyclooxygenase, PAD, peripheral arterial disease, DM, diabetes mellitus, platelets, LTA, light transmittance aggregometry, pharmacodynamics, MI, myocardial infarction, PAR, protease-activated receptor, TRAP, thrombin receptor activating peptide, PD, pharmacodynamic, VASP, vasodilator-stimulated phosphoprotein, DAPT, dual antiplatelet therapy

URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid________::5ddf216a2bf07dd5e1dc9c7d5da38d0b
https://pubmed.ncbi.nlm.nih.gov/31998847

المؤلفون: Niamh Moran, Michael C. Berndt, Jane Frances Arthur, Justin Raymond Hamilton, Robert K. Andrews, Naadiya Carrim, Elizabeth E. Gardiner, Pat Metharom

المصدر: Redox Biology

مصطلحات موضوعية: WT, wild type, Platelets, Blood Platelets, CRP, collagen-related peptide, Clinical Biochemistry, Receptors GPIbα, 030204 cardiovascular system & hematology, Biochemistry, 03 medical and health sciences, Mice, 0302 clinical medicine, Thrombin, ROS, reactive oxygen species, PAR1 and PAR4, Chlorocebus aethiops, medicine, Animals, Humans, Platelet, Nk, Naja kaouthia protease, Receptor, PAR-1, Platelet activation, Receptor, 030304 developmental biology, chemistry.chemical_classification, 0303 health sciences, Reactive oxygen species, NADPH oxidase, biology, Activator (genetics), Organic Chemistry, NADPH Oxidases, Platelet Glycoprotein GPIb-IX Complex, 3. Good health, chemistry, Focal Adhesion Kinase 1, COS Cells, biology.protein, NADPH Oxidase 1, PAR, protease-activated receptor, Receptors, Thrombin, Reactive Oxygen Species, medicine.drug, Research Paper

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6afa7d601176a919050c5274cc5931a7
http://europepmc.org/articles/PMC4656914

المؤلفون: Goggs, Robert, Williams, Christopher M., Mellor, Harry, Poole, Alastair W.

المصدر: Biochemical Journal

مصطلحات موضوعية: rho GTP-Binding Proteins, Syk, spleen tyrosine kinase, Platelet Aggregation, TRIO, triple functional domain containing protein, Review Article, Cdc42, cell division control protein 42, Rac, Ras-related C3 botulinum toxin substrate, ROCK, Rho kinase, MLC, myosin light chain, shape change, Ena, enabled, MTSS1, metastasis suppressor protein 1, FcR, Fc receptor, AP-MS, affinity-purification mass spectrometry, ARP2/3, actin related protein 2/3 complex, Rif, Rho in filopodia (RhoF), WASP, Wiskott–Aldrich syndrome protein, ECM, extracellular matrix, LARG, leukaemia-associated Rho GEF (ARHGEF12), secretion, PI3K, phosphoinositide 3-kinase, PREX-1, PI(3,4,5)P3-dependent Rac exchanger 1 protein, Signal Transduction, VWF, von Willebrand factor, Blood Platelets, PAR, protease activated receptor, NSF, N-ethylmaleimide-sensitive factor, CRP, collagen-related peptide, SNARE, soluble N-ethylmaleimide attachment protein receptors, PF4, platelet factor-4, GEF, guanine nucleotide exchange factor, PLC, phospholipase C, PAK, P21-activated kinase, LAT, linker for activation of T-cells, PKC, protein kinase C, Animals, Humans, cell division control protein 42 (Cdc42), thrombosis, Rho GTPase, Ras homology family GTPase, Rif, ITAM, immunoreceptor tyrosine-based activation motif, Platelet Activation, GDI, guanine nucleotide dissociation inhibitor, RhoG, IMD, IRSp53 and MIM homology domain, ELMO, engulfment and cell motility, VAMP, vesicle-associated membrane protein, F-actin, filamentous actin, TCR, T-cell receptor, GAP, GTPase activating protein, ARHGEF, Rho guanine nucleotide exchange factor, GP, glycoprotein, VASP, vasodilator-stimulated phosphoprotein, DOCK, dedicator of cytokinesis

URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid________::8dee12c58f70730a3a55910e7d6987a6
http://europepmc.org/articles/PMC4357237

المؤلفون: Renata Gustafsson, Kristofer Rubin, Vahid Reyhani, Pegah Seddigh, Bengt Guss, Lars Rask

المصدر: Biochemical Journal

مصطلحات موضوعية: interface matrix, collagen type I, Integrin, c-RGD, cyclic RGD, SPR, surface plasmon resonance, protein binding, Fibril, Biochemistry, Collagen Type I, DMEM, Dulbecco’s modified Eagle’s medium, PDGF, platelet-derived growth factor, Fibrin, Cell Line, Extracellular matrix, Mice, Thrombin, medicine, Animals, gel contraction, fibrin, Molecular Biology, Cells, Cultured, Col I, collagen type I, Integrin alphaVbeta3, biology, Chemistry, PAE, porcine aortic endothelial, PBS-T, 0.05% Tween 20 in PBS, CNE, collagen-binding protein from Steptococcus equi, Cell Biology, Molecular biology, Extracellular Matrix, ECM, extracellular matrix, Cell biology, Fibronectin, biology.protein, PAR, protease-activated receptor, Gels, Discoidin domain, Research Article, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d0f54b9fb3b20574f372e176621b9eed
https://doi.org/10.1042/bj20140201

المؤلفون: Jumeau, Céline, Rupin, Alain, Chieng-Yane, Pauline, Mougenot, Nathalie, Zahr, Noël, David-Dufilho, Monique, Hatem, Stéphane N.

المساهمون: Institut de Recherches Internationales Servier [Suresnes] (IRIS), Unité de Recherche sur les Maladies Cardiovasculaires, du Métabolisme et de la Nutrition = Institute of cardiometabolism and nutrition (ICAN), Université Pierre et Marie Curie - Paris 6 (UPMC)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Institut National de la Santé et de la Recherche Médicale (INSERM)-CHU Pitié-Salpêtrière [AP-HP], Sorbonne Université (SU)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU), FRS Consulting, Phénotypage du petit animal (UMS28), Université Pierre et Marie Curie - Paris 6 (UPMC), CIC Paris Est, Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Institut National de la Santé et de la Recherche Médicale (INSERM)-CHU Pitié-Salpêtrière [AP-HP], CHU Pitié-Salpêtrière [AP-HP], Sorbonne Université (SU)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP), This work was supported by the Servier Research Institute and Laboratories, (contract n°122694/BR/VO), the Agence Nationale de la Recherche (ANR), Paris (National program 'Investissements d'avenir': ANR-10-IAHU-05), and the European Network for Translational Research in AF (FP7 EUTRAF- 261057 and H2020CATCH-ME 633196). Dr. Jumeau received a CIFRE grant from the French Ministry of Education and Research, Paris (2012-0374)., ANR-10-IAHU-0005,ICAN,Institut de Cardiologie-Métabolisme-Nutrition(2010), European Project: 261057,EC:FP7:HEALTH,FP7-HEALTH-2010-single-stage,EUTRAF(2010), European Project: 633196,H2020,H2020-PHC-2014-two-stage,CATCH ME(2015), Unité de Recherche sur les Maladies Cardiovasculaires, du Métabolisme et de la Nutrition = Research Unit on Cardiovascular and Metabolic Diseases (ICAN), Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU)-Sorbonne Université (SU), Centre d'investigation clinique Paris Est [CHU Pitié Salpêtrière] (CIC Paris-Est), Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU), Centre d'investigation clinique pluridisciplinaire [CHU Pitié Salpêtrière] (CIC-P 1421), Institut National de la Santé et de la Recherche Médicale (INSERM)-CHU Pitié-Salpêtrière [AP-HP], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU)-Institut National de la Santé et de la Recherche Médicale (INSERM)-CHU Pitié-Salpêtrière [AP-HP], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU), Administateur, HAL Sorbonne Université, Instituts Hospitalo-Universitaires - Institut de Cardiologie-Métabolisme-Nutrition - - ICAN2010 - ANR-10-IAHU-0005 - IAHU - VALID, The European Network for Translational Research in Atrial Fibrillation - EUTRAF - - EC:FP7:HEALTH2010-11-01 - 2015-10-31 - 261057 - VALID, Characterizing Atrial fibrillation by Translating its Causes into Health Modifiers in the Elderly - CATCH ME - - H20202015-05-01 - 2019-04-30 - 633196 - VALID

المصدر: Jacc. Basic to Translational Science
JACC: Basic to Translational Science
JACC : Basic to Translational Science
JACC : Basic to Translational Science, Elsevier on behalf of the American College of Cardiology Foundation, 2016, 1 (5), ⟨10.1016/j.jacbts.2016.05.002⟩
JACC : Basic to Translational Science, 2016, 1 (5), ⟨10.1016/j.jacbts.2016.05.002⟩
JACC: Basic to Translational Science, Vol 1, Iss 5, Pp 328-339 (2016)

مصطلحات موضوعية: 0301 basic medicine, lcsh:Diseases of the circulatory (Cardiovascular) system, medicine.medical_specialty, AF, atrial fibrillation, medicine.drug_class, heart failure, atrial arrhythmia, 030204 cardiovascular system & hematology, CTGF, connective tissue growth factor, 03 medical and health sciences, 0302 clinical medicine, Thrombin, [SDV.MHEP.CSC]Life Sciences [q-bio]/Human health and pathology/Cardiology and cardiovascular system, Fibrosis, Internal medicine, medicine, ANP, atrial natriuretic peptide, NFATc3, nuclear factor of activated T cells 3, direct thrombin inhibitor, remodeling, DTI, direct thrombin inhibitor, BNP, brain natriuretic peptide, business.industry, Anticoagulant, anticoagulant, Pre-Clinical Research, Atrial fibrillation, medicine.disease, [SDV.MHEP.CSC] Life Sciences [q-bio]/Human health and pathology/Cardiology and cardiovascular system, 3. Good health, CTGF, 030104 developmental biology, lcsh:RC666-701, Direct thrombin inhibitor, Heart failure, Cardiology, MI, myocardial infarction, PAR, protease-activated receptor, PAI, plasminogen activator inhibitor, Cardiology and Cardiovascular Medicine, business, MHC, myosin heavy chain, medicine.drug, Discovery and development of direct thrombin inhibitors

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::535d37fb389ee78db0d355ec1fcf1f86
https://pubmed.ncbi.nlm.nih.gov/27642643

المؤلفون: Peter Holzer

المصدر: Pharmacology & Therapeutics

مصطلحات موضوعية: TNBS, trinitrobenzene sulfonic acid, CCK, cholecystokinin, TRPC6, TRPP, TRPM, transient receptor potential melastatin, Inflammatory bowel disease, TRPC4, CGRP, calcitonin gene-related peptide, Transient receptor potential channel, Transient Receptor Potential Channels, TRPA, transient receptor potential ankyrin, siRNA, small interfering ribonucleic acid, Pharmacology (medical), ICC, interstitial cell of Cajal, 5-HT, 5-hydroxytryptamine, Chemistry, Smooth muscle contraction, GI, gastrointestinal, DRG, dorsal root ganglion, AITC, allyl isothiocyanate, Hyperalgesia, Taste, TRP, transient receptor potential, TRPV4, medicine.medical_specialty, Digestive System Diseases, mRNA, messenger ribonucleic acid, Chemesthesis, TRPM5, Transducers, TRPM6, Pain, PKD, polycystic kidney disease, TRPA1, Article, Gastrointestinal cancer, TRPM7, DSS, dextran sulfate sodium, Internal medicine, Chemosensation, Hypersensitivity, medicine, Animals, Humans, TRPP, transient receptor potential polycystin, TRPV, transient receptor potential vanilloid, GPCR, G protein-coupled receptor, Inflammation, Pharmacology, Gastrointestinal motility, Mechanosensation, TRPV1, Endocrinology, RNA, ribonucleic acid, PAR, protease-activated receptor, TRPC, transient receptor potential canonical (or classical), TRPV6

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::47e30e0cdcec0ffd5b41425dd07e4eb1

المؤلفون: Luize G. Lima, Robson Q. Monteiro

المصدر: Bioscience Reports, Vol 33, Iss 5, p e00064 (2013)
Bioscience Reports

مصطلحات موضوعية: MV, microvesicle, Cell, lcsh:Life, lcsh:QR1-502, Review Article, Biochemistry, Trousseau’s syndrome, lcsh:Microbiology, Metastasis, NET, neutrophil extracellular trap, Neoplasms, Neoplasm Metastasis, Receptor, FIX, factor IX, PS, phosphatidylserine, Thrombosis, VEGF, vascular endothelial growth factor, Blood Coagulation Factors, medicine.anatomical_structure, Coagulation, FVIIa, factor VIIa, Disease Progression, MMP, matrix metalloprotease, FX, factor X, NK, natural killer, protease-activated receptor, S1, Biophysics, Antineoplastic Agents, Biology, blood coagulation, Tissue factor, medicine, Animals, Humans, metastasis, Molecular Biology, tumour growth, Cancer, Anticoagulants, Cell Biology, FVIII, factor VIII, medicine.disease, tissue factor, Microvesicles, lcsh:QH501-531, Immunology, TF, tissue factor, Cancer research, PAR, protease-activated receptor

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e50cac7ae5ed6698d5b841e2f1dfa72a
http://www.bioscirep.org/bsr/033/e064/bsr033e064.htm