المؤلفون: Alexander H. Staudacher, Vasilios Liapis, Nicole L. Wittwer, William Tieu, Hiu Chun Lam, Jeanette Leusen, Michael P. Brown

المصدر: Biomedicine & Pharmacotherapy, Vol 151, Iss , Pp 113090- (2022)

مصطلحات موضوعية: NOTAM, FcγR, APOMAB, ChDAB4, Zirconium-89, PBD dimer, Therapeutics. Pharmacology, RM1-950

وصف الملف: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S0753332222004796; https://doaj.org/toc/0753-3322

URL الوصول: https://doaj.org/article/1e87d14864f544fd89df4097ec0b1c0c

المؤلفون: Yong Ma, Buyun Chen, Donglu Zhang

المصدر: Journal of Pharmaceutical Analysis, Vol 10, Iss 3, Pp 247-252 (2020)

مصطلحات موضوعية: Nuclease P1, UPLC-MS/MS, DNA quantitation, DNA alkylation, Pyrrolobenzodiazepine (PBD-Dimer), Therapeutics. Pharmacology, RM1-950

وصف الملف: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2095177920303981; https://doaj.org/toc/2095-1779

URL الوصول: https://doaj.org/article/6f745856436d46438683f302eb3e6d91

المؤلفون: Hartley, John A.^Aff5

المساهمون: Parnham, Michael J., Series editor^Aff1, Bruinvels, Jacques, Series editor^Aff2, Grawunder, Ulf, editor^Aff3, Barth, Stefan, editor^Aff4

المصدر: Next Generation Antibody Drug Conjugates (ADCs) and Immunotoxins. :29-46

المؤلفون: Juan Carlos Cordova, Sheng Sun, Jeffrey Bos, Srinath Thirumalairajan, Sanjeevani Ghone, Miyako Hirai, Ricarda A. Busse, Julia S. v. der Hardt, Ian Schwartz, Jieyu Zhou

المصدر: Journal of Clinical Medicine, Vol 10, Iss 3, p 552 (2021)

مصطلحات موضوعية: antibody–drug conjugate, membrane purification, pyrrolobenzodiazepine (PBD) dimer, cation exchange (CEX), hydrophobic interaction (HIC), tandem-mode purification, Medicine

وصف الملف: electronic resource

Relation: https://www.mdpi.com/2077-0383/10/3/552; https://doaj.org/toc/2077-0383

URL الوصول: https://doaj.org/article/151989719b81410a84634294c4d708d2

المؤلفون: Donglu Zhang, Yong Ma, Buyun Chen

المصدر: Journal of Pharmaceutical Analysis
Journal of Pharmaceutical Analysis, Vol 10, Iss 3, Pp 247-252 (2020)

مصطلحات موضوعية: Original article, Pharmaceutical Science, Pyrrolobenzodiazepine, 02 engineering and technology, Pharmacy, 01 natural sciences, Deoxyribonucleotides, Analytical Chemistry, chemistry.chemical_compound, Nuclease P1, Drug Discovery, Electrochemistry, DNA quantitation, Spectroscopy, DNA alkylation, Nuclease, Chromatography, biology, lcsh:RM1-950, 010401 analytical chemistry, 021001 nanoscience & nanotechnology, 0104 chemical sciences, DNA Alkylation, lcsh:Therapeutics. Pharmacology, Deoxyadenosine monophosphate, chemistry, Linear range, UPLC-MS/MS, biology.protein, 0210 nano-technology, Digestion, Pyrrolobenzodiazepine (PBD-Dimer), DNA

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c7977e31dd10bb7eceaca05556c35291
https://doi.org/10.1016/j.jpha.2020.05.011

المؤلفون: R. James Christie, Arnaud C. Tiberghien, Qun Du, Binyam Bezabeh, Ryan Fleming, Amanda Shannon, Shenlan Mao, Shannon Breen, Jing Zhang, Haihong Zhong, Jay Harper, Herren Wu, Philip W. Howard, Changshou Gao

المصدر: Antibodies, Vol 6, Iss 4, p 20 (2017)

مصطلحات موضوعية: PBD dimer, thiosuccinimide hydrolysis, N-phenyl maleimide, retro-Michael reaction, serum stability, ADC, site-specific conjugation, Immunologic diseases. Allergy, RC581-607

وصف الملف: electronic resource

Relation: https://www.mdpi.com/2073-4468/6/4/20; https://doaj.org/toc/2073-4468

URL الوصول: https://doaj.org/article/d8a3eda79f854774ad8483d0cf099f77

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المؤلفون: Melissa Schutten, Brandon Latifi, Ola Saad, Steven T Laing, Shabkhaiz Masih, Jintang He, Isabel Figueroa, Katherine R. Kozak, Douglas D. Leipold, Randall C. Dere, M. Violet Lee, Brian R. Vuillemenot, Andrew Polson, Keyang Xu, Ben-Quan Shen, Montserrat Carrasco-Triguero, Luna Liu, Dian Su, Victor Yip, Bing Zheng, Amrita V. Kamath

المصدر: mAbs

مصطلحات موضوعية: 0301 basic medicine, Antibody-drug conjugate, Immunoconjugates, Metabolic Clearance Rate, Immunology, acute myeloid leukemia, Pharmacology, Benzodiazepines, Mice, 03 medical and health sciences, Species Specificity, Pharmacokinetics, Report, hemic and lymphatic diseases, Preclinical pharmacokinetics, Animals, Humans, Immunology and Allergy, Medicine, receptor occupancy, Lectins, C-Type, Pyrroles, Receptor, neoplasms, business.industry, PBD dimer, Antibodies, Monoclonal, Treatment options, Myeloid leukemia, Rats, Macaca fascicularis, 030104 developmental biology, Leukemia, Myeloid, Area Under Curve, Immunoglobulin G, Receptors, Mitogen, Pharmacodynamics, Acute Disease, CLL-1, business, pharmacokinetics, Conjugate

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::88bf3a1e3a6f99e410d6d7cec20c06c3
https://doi.org/10.1080/19420862.2018.1517565

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المؤلفون: Vasilios Liapis, Michael P. Brown, Nicole L Wittwer, Alexander H. Staudacher, William Tieu

المساهمون: Staudacher, Alexander H, Liapis, Vasilios, Tieu, William, Wittwer, Nicole L, Brown, Michael P

المصدر: Journal of controlled release : official journal of the Controlled Release Society. 327

مصطلحات موضوعية: Antibody-drug conjugate, La/SSB, medicine.medical_treatment, Cell, zirconium-89, Pharmaceutical Science, 02 engineering and technology, 03 medical and health sciences, In vivo, iodine-124, Cell Line, Tumor, Tumor-Associated Macrophages, Bystander effect, medicine, Macrophage, 030304 developmental biology, 0303 health sciences, biology, Chemistry, Macrophages, PBD dimer, Antibodies, Monoclonal, bystander killing, 021001 nanoscience & nanotechnology, In vitro, macrophages, medicine.anatomical_structure, Pharmaceutical Preparations, Radioimmunotherapy, biology.protein, Cancer research, APOMAB, antibody drug conjugate, Antibody, 0210 nano-technology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::66caac8ac7d671ad7c7c338ec93ec784
https://pubmed.ncbi.nlm.nih.gov/32946876