المؤلفون: Natarajan P; From the Department of Medicine and Division of Cardiology, Massachusetts General Hospital and Harvard Medical School - both in Boston.

المصدر: The New England journal of medicine [N Engl J Med] 2024 Sep 12; Vol. 391 (10), pp. 957-959. Date of Electronic Publication: 2024 May 29.

نوع المنشور: Editorial

بيانات الدورية: Publisher: Massachusetts Medical Society Country of Publication: United States NLM ID: 0255562 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1533-4406 (Electronic) Linking ISSN: 00284793 NLM ISO Abbreviation: N Engl J Med Subsets: MEDLINE

مواضيع طبية MeSH: Coronary Artery Disease*/genetics , Coronary Artery Disease*/metabolism , Coronary Artery Disease*/therapy , PCSK9 Inhibitors*/pharmacology , PCSK9 Inhibitors*/therapeutic use , RNA, Small Interfering*/administration & dosage , RNAi Therapeutics*/methods, Humans ; Proprotein Convertase 9/genetics ; Proprotein Convertase 9/metabolism ; Angiopoietin-Like Protein 3/antagonists & inhibitors ; Angiopoietin-Like Protein 3/genetics ; Angiopoietin-Like Protein 3/metabolism ; Apolipoprotein C-III/antagonists & inhibitors ; Apolipoprotein C-III/genetics ; Apolipoprotein C-III/metabolism ; Gain of Function Mutation ; Genetic Predisposition to Disease

المؤلفون: Marco-Benedí V; Hospital Universitario Miguel Servet, IIS Aragón, CIBERCV, Saragossa, Spain. vmarcobenedi@gmail.com.; Unidad de Lípidos, Hospital Universitario Miguel Servet, Avda Isabel La Católica 1-3, 50009, Saragossa, Spain. vmarcobenedi@gmail.com., Sánchez-Hernández RM; Sección de Endocrinología y Nutrición, Complejo Hospitalario Universitario Insular Materno-Infantil, Instituto Universitario de Investigaciones Biomédicas y Sanitarias de La Universidad de Las Palmas de Gran Canaria, de Las Palmas de Gran Canaria, Spain., Díaz JL; Unidad de Lípidos y Riesgo Cardiovascular, Medicina Interna, Hospital Universitario A Coruña, A Coruña, Spain., Jarauta E; Hospital Universitario Miguel Servet, IIS Aragón, CIBERCV, Saragossa, Spain.; Unidad de Lípidos, Hospital Universitario Miguel Servet, Avda Isabel La Católica 1-3, 50009, Saragossa, Spain., Suárez-Tembra M; Unidad de Lípidos y Riesgo Cardiovascular Hospital San Rafael, A Coruña, Spain., Pintó X; Unidad de Lípidos y Riesgo Cardiovascular, Servicio de Medicina Interna, Hospital Universitario de Bellvitge, CIBEROBN, Barcelona, Spain., Morillas C; Unidad de Lípidos Clínico-Epidemiológica, Hospital Universitario Dr. Peset, Valencia, Spain., Plana N; Unitat de Medicina Vascular I Metabolisme, Hospital Sant Joan de Reus, IISPV, CIBERDEM, Universitat Rovira I Virgili, Reus, Spain., Pedro-Botet J; Unidad de Lípidos y Riesgo Vascular, Servicio de Endocrinología y Nutrición, Hospital del Mar, Universidad Autónoma de Barcelona, Barcelona, Spain., Civeira F; Hospital Universitario Miguel Servet, IIS Aragón, CIBERCV, Saragossa, Spain. civeira@unizar.es.; Unidad de Lípidos, Hospital Universitario Miguel Servet, Avda Isabel La Católica 1-3, 50009, Saragossa, Spain. civeira@unizar.es.

المصدر: Lipids in health and disease [Lipids Health Dis] 2024 Sep 10; Vol. 23 (1), pp. 290. Date of Electronic Publication: 2024 Sep 10.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: BioMed Central Country of Publication: England NLM ID: 101147696 Publication Model: Electronic Cited Medium: Internet ISSN: 1476-511X (Electronic) Linking ISSN: 1476511X NLM ISO Abbreviation: Lipids Health Dis Subsets: MEDLINE

مواضيع طبية MeSH: PCSK9 Inhibitors*/therapeutic use , Secondary Prevention*/methods , Cardiovascular Diseases*/prevention & control , Cardiovascular Diseases*/drug therapy , Cholesterol, LDL*/blood, Humans ; Male ; Female ; Middle Aged ; Aged ; Hypercholesterolemia/drug therapy ; Hypercholesterolemia/blood ; Primary Prevention/methods ; Anticholesteremic Agents/therapeutic use ; Registries ; Proprotein Convertase 9/metabolism ; Antibodies, Monoclonal, Humanized/therapeutic use

المؤلفون: Yang Y; Department of Endocrinology, the Second Affiliated Hospital, Kunming Medical University, Kunming, Yunnan, China., Wang Y; Department of Epidemiology and Biostatistics, School of Public Health, Kunming Medical University, Kunming, Yunnan, China., Wang Y; Department of Endocrinology, the Second Affiliated Hospital, Kunming Medical University, Kunming, Yunnan, China., Ke T; Department of Endocrinology, the Second Affiliated Hospital, Kunming Medical University, Kunming, Yunnan, China., Zhao L; Department of Endocrinology, the Second Affiliated Hospital, Kunming Medical University, Kunming, Yunnan, China.

المصدر: PeerJ [PeerJ] 2024 Aug 14; Vol. 12, pp. e17676. Date of Electronic Publication: 2024 Aug 14 (Print Publication: 2024).

نوع المنشور: Journal Article

بيانات الدورية: Publisher: PeerJ Inc Country of Publication: United States NLM ID: 101603425 Publication Model: eCollection Cited Medium: Internet ISSN: 2167-8359 (Electronic) Linking ISSN: 21678359 NLM ISO Abbreviation: PeerJ Subsets: MEDLINE

مواضيع طبية MeSH: Diabetes Mellitus, Type 2*/complications , Diabetes Mellitus, Type 2*/drug therapy , PCSK9 Inhibitors* , Rats, Sprague-Dawley* , Cognitive Dysfunction*/drug therapy , Cognitive Dysfunction*/etiology, Animals ; Male ; Rats ; Hippocampus/drug effects ; Hippocampus/metabolism ; Hippocampus/pathology ; Diabetes Mellitus, Experimental/complications ; Diabetes Mellitus, Experimental/drug therapy ; Disease Models, Animal ; Neurons/drug effects ; Neurons/metabolism ; Neurons/pathology ; Proprotein Convertase 9

المؤلفون: Hosseini K; Cardiac Primary Prevention Research Center, Cardiovascular Diseases Research Institute, Tehran University of Medical Sciences, Tehran, 1419733141, Iran.; Cardiovascular Diseases Research Institute, Tehran Heart Center, Tehran University of Medical Sciences, Tehran, 1419733141, Iran., Soleimani H; Cardiac Primary Prevention Research Center, Cardiovascular Diseases Research Institute, Tehran University of Medical Sciences, Tehran, 1419733141, Iran. hamid.r.soleimani90@gmail.com.; Cardiovascular Diseases Research Institute, Tehran Heart Center, Tehran University of Medical Sciences, Tehran, 1419733141, Iran. hamid.r.soleimani90@gmail.com.; Non-Communicable Diseases Research Center, Endocrinology and Metabolism Population Sciences Institute, Tehran University of Medical Sciences, Tehran, 1411713139, Iran. hamid.r.soleimani90@gmail.com., Maleki S; Cardiac Primary Prevention Research Center, Cardiovascular Diseases Research Institute, Tehran University of Medical Sciences, Tehran, 1419733141, Iran.; School of Medicine, Guilan University of Medical Sciences (GUMS), Rasht, Guilan Province, Iran., Nasrollahizadeh A; Cardiac Primary Prevention Research Center, Cardiovascular Diseases Research Institute, Tehran University of Medical Sciences, Tehran, 1419733141, Iran.; Cardiovascular Diseases Research Institute, Tehran Heart Center, Tehran University of Medical Sciences, Tehran, 1419733141, Iran., Tayebi S; Centre for Clinical Research Sormland, Uppsala University, Uppsala, SE, Sweden., Nelson J; California Cardiovascular Institute, Fresno, CA, USA., Heffron SP; Center for the Prevention of Cardiovascular Disease, Leon H. Charney Division of Cardiology, NYU Langone Health, New York University Grossman School of Medicine, New York, NY, USA.

المصدر: BMC cardiovascular disorders [BMC Cardiovasc Disord] 2024 Jul 30; Vol. 24 (1), pp. 395. Date of Electronic Publication: 2024 Jul 30.

نوع المنشور: Systematic Review; Meta-Analysis; Journal Article

بيانات الدورية: Publisher: BioMed Central Country of Publication: England NLM ID: 100968539 Publication Model: Electronic Cited Medium: Internet ISSN: 1471-2261 (Electronic) Linking ISSN: 14712261 NLM ISO Abbreviation: BMC Cardiovasc Disord Subsets: MEDLINE

مواضيع طبية MeSH: Acute Coronary Syndrome*/drug therapy , Acute Coronary Syndrome*/mortality , Acute Coronary Syndrome*/blood , Acute Coronary Syndrome*/diagnosis , Biomarkers*/blood , PCSK9 Inhibitors*, Humans ; Anticholesteremic Agents/adverse effects ; Anticholesteremic Agents/administration & dosage ; Anticholesteremic Agents/therapeutic use ; Cholesterol, LDL/blood ; Drug Administration Schedule ; Dyslipidemias/drug therapy ; Dyslipidemias/blood ; Dyslipidemias/diagnosis ; Dyslipidemias/mortality ; Hydroxymethylglutaryl-CoA Reductase Inhibitors/administration & dosage ; Hydroxymethylglutaryl-CoA Reductase Inhibitors/therapeutic use ; Hydroxymethylglutaryl-CoA Reductase Inhibitors/adverse effects ; Myocardial Infarction/mortality ; Myocardial Infarction/drug therapy ; Myocardial Infarction/diagnosis ; Myocardial Revascularization ; Observational Studies as Topic ; Randomized Controlled Trials as Topic ; Risk Factors ; Serine Proteinase Inhibitors/adverse effects ; Serine Proteinase Inhibitors/therapeutic use ; Serine Proteinase Inhibitors/administration & dosage ; Time Factors ; Treatment Outcome

المؤلفون: Kehinde IO; Molecular Bio-computation and Drug Design Laboratory, School of Health Sciences, University of KwaZulu-Natal, Westville Campus, Durban, South Africa.; Department of Pharmaceutical and Medicinal Chemistry, College of Pharmacy, Afe Babalola University, Ado-Ekiti, Nigeria., Akawa O; Department of Pharmaceutical and Medicinal Chemistry, College of Pharmacy, Afe Babalola University, Ado-Ekiti, Nigeria., Adewumi AT; Department of Life and Consumer Sciences, University of South Africa, Florida Campus, Johannesburg, South Africa., Rabbad AH; Molecular Bio-computation and Drug Design Laboratory, School of Health Sciences, University of KwaZulu-Natal, Westville Campus, Durban, South Africa., Soliman MES; Molecular Bio-computation and Drug Design Laboratory, School of Health Sciences, University of KwaZulu-Natal, Westville Campus, Durban, South Africa.

المصدر: Journal of cellular biochemistry [J Cell Biochem] 2024 Jul; Vol. 125 (7), pp. e30581. Date of Electronic Publication: 2024 May 15.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Wiley-Liss Country of Publication: United States NLM ID: 8205768 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1097-4644 (Electronic) Linking ISSN: 07302312 NLM ISO Abbreviation: J Cell Biochem Subsets: MEDLINE

مواضيع طبية MeSH: PCSK9 Inhibitors* , Molecular Dynamics Simulation* , Proprotein Convertase 9*/metabolism , Proprotein Convertase 9*/chemistry , Atherosclerosis*/drug therapy , Atherosclerosis*/metabolism, Humans ; Drug Design ; Cardiovascular Diseases/drug therapy ; Pharmacophore

المؤلفون: Dal Pino B; Lipoapheresis Unit - Reference center for Diagnosis and Treatment of Inherited Dyslipidemias, Fondazione Toscana 'Gabriele Monasterio', Pisa, Italy., Sbrana F; Lipoapheresis Unit - Reference center for Diagnosis and Treatment of Inherited Dyslipidemias, Fondazione Toscana 'Gabriele Monasterio', Pisa, Italy.

المصدر: Acta cardiologica [Acta Cardiol] 2024 Jul; Vol. 79 (5), pp. 625-626. Date of Electronic Publication: 2024 Feb 09.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Taylor & Francis Country of Publication: England NLM ID: 0370570 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1784-973X (Electronic) Linking ISSN: 00015385 NLM ISO Abbreviation: Acta Cardiol Subsets: MEDLINE

مواضيع طبية MeSH: PCSK9 Inhibitors* , Medication Adherence*, Humans ; Male ; Female ; Middle Aged ; Anticholesteremic Agents/therapeutic use ; Anticholesteremic Agents/adverse effects ; Antibodies, Monoclonal, Humanized/adverse effects ; Antibodies, Monoclonal, Humanized/therapeutic use ; Aged ; Cholesterol, LDL/blood ; Hypercholesterolemia/drug therapy ; Proprotein Convertase 9

المؤلفون: Zhang N; Department of Laboratory Medicine, Peoples Hospital of Deyang City, No 173, the First Section of North Taishan Road, Deyang, 618000, China. znd1984@126.com., Ji C; Department of Laboratory Medicine, Peoples Hospital of Deyang City, No 173, the First Section of North Taishan Road, Deyang, 618000, China., Liu L; Department of Medical Technology, Chengdu University of Traditional Chinese Medicine, Chengdu, 610075, China., Ye E; Department of Laboratory Medicine, Peoples Hospital of Deyang City, No 173, the First Section of North Taishan Road, Deyang, 618000, China., Yuan C; Department of Laboratory Medicine, Peoples Hospital of Deyang City, No 173, the First Section of North Taishan Road, Deyang, 618000, China.

المصدر: Calcified tissue international [Calcif Tissue Int] 2024 Jul; Vol. 115 (1), pp. 53-62. Date of Electronic Publication: 2024 May 24.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Springer Verlag Country of Publication: United States NLM ID: 7905481 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1432-0827 (Electronic) Linking ISSN: 0171967X NLM ISO Abbreviation: Calcif Tissue Int Subsets: MEDLINE

مواضيع طبية MeSH: Osteoporosis*/epidemiology , Mendelian Randomization Analysis* , PCSK9 Inhibitors* , Bone Density*/drug effects, Humans ; Middle Aged ; Female ; Male ; Adult ; Mediation Analysis ; Cholesterol, LDL/blood ; Proprotein Convertase 9

المؤلفون: Rivera FB; Department of Medicine, Lincoln Medical Center, New York, NY, USA., Cha SW; Cebu Institute of Medicine, Cebu City, Philippines., Magalong JV; College of Medicine, San Beda University, Manila, Philippines., Bantayan NRB; University of the Philippines College of Medicine, Manila, Philippines., Cruz LLA; University of the Philippines College of Medicine, Manila, Philippines., Arias-Aguirre E; Cebu Institute of Medicine, Cebu City, Philippines., Aguirre Z; Cebu Institute of Medicine, Cebu City, Philippines., Varona MC; Cebu Institute of Medicine, Cebu City, Philippines., Co EMF; Cebu Institute of Medicine, Cebu City, Philippines., Lumbang GNO; Cebu Institute of Medicine, Cebu City, Philippines., Enkhmaa B; Division of Endocrinology, Diabetes & Metabolism, UC Davis Health, Davis, CA, USA.

المصدر: Current medical research and opinion [Curr Med Res Opin] 2024 Jul; Vol. 40 (7), pp. 1103-1121. Date of Electronic Publication: 2024 Jun 11.

نوع المنشور: Journal Article; Meta-Analysis

بيانات الدورية: Publisher: Informa Healthcare Country of Publication: England NLM ID: 0351014 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1473-4877 (Electronic) Linking ISSN: 03007995 NLM ISO Abbreviation: Curr Med Res Opin Subsets: MEDLINE

مواضيع طبية MeSH: Antibodies, Monoclonal, Humanized*/adverse effects , Antibodies, Monoclonal, Humanized*/administration & dosage , PCSK9 Inhibitors* , Antibodies, Monoclonal*/adverse effects , Antibodies, Monoclonal*/therapeutic use, Humans ; Female ; Proprotein Convertase 9/metabolism ; Male ; Anticholesteremic Agents/adverse effects ; Anticholesteremic Agents/therapeutic use ; Diabetes Mellitus/drug therapy ; Diabetes Mellitus/epidemiology

المؤلفون: Sheng F; Medical Affairs, Amgen K.K., Wang AY; Center for Observational Research, Amgen Australia., Miyawaki K; Medical Affairs, Amgen K.K., Tsuchiya T; Medical Affairs, Amgen K.K., Osada N; Medical Affairs, Amgen K.K., Miller R; Syneos Health., Fu Z; Syneos Health., Okamura T; Department of Preventive Medicine and Public Health, Keio University School of Medicine.

المصدر: Circulation journal : official journal of the Japanese Circulation Society [Circ J] 2024 Sep 25; Vol. 88 (10), pp. 1629-1636. Date of Electronic Publication: 2024 Mar 01.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Japanese Circulation Society Country of Publication: Japan NLM ID: 101137683 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1347-4820 (Electronic) Linking ISSN: 13469843 NLM ISO Abbreviation: Circ J Subsets: MEDLINE

مواضيع طبية MeSH: Antibodies, Monoclonal, Humanized*/therapeutic use , PCSK9 Inhibitors* , Anticholesteremic Agents*/therapeutic use, Humans ; Japan/epidemiology ; Retrospective Studies ; Male ; Middle Aged ; Female ; Aged ; Databases, Factual ; Adult ; Hyperlipoproteinemia Type II/drug therapy ; Hyperlipoproteinemia Type II/epidemiology ; Hyperlipoproteinemia Type II/blood ; Ezetimibe/therapeutic use ; Proprotein Convertase 9

المؤلفون: Ogura M; Department of Clinical Laboratory Technology, Faculty of Medical Science, Juntendo University.

المصدر: Circulation journal : official journal of the Japanese Circulation Society [Circ J] 2024 Sep 25; Vol. 88 (10), pp. 1637-1638. Date of Electronic Publication: 2024 Mar 29.

نوع المنشور: Editorial; Journal Article

بيانات الدورية: Publisher: Japanese Circulation Society Country of Publication: Japan NLM ID: 101137683 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1347-4820 (Electronic) Linking ISSN: 13469843 NLM ISO Abbreviation: Circ J Subsets: MEDLINE

مواضيع طبية MeSH: PCSK9 Inhibitors*, Humans ; Anticholesteremic Agents/therapeutic use ; Cholesterol, LDL/blood ; Proprotein Convertase 9