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المؤلفون: Jin Sun Park, Yea Hyun Leem, Hee Sun Kim, Do Yeon Kim, Jung Eun Park
المصدر: Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology. 16(2)
مصطلحات موضوعية: 0301 basic medicine, Lipopolysaccharides, Male, PF-2545920, Phosphodiesterase Inhibitors, Immunology, Neuroscience (miscellaneous), Anti-Inflammatory Agents, Substantia nigra, Striatum, Pharmacology, Proinflammatory cytokine, 03 medical and health sciences, chemistry.chemical_compound, Mice, 0302 clinical medicine, Parkinsonian Disorders, Immunology and Allergy, Animals, Protein kinase A, Protein kinase B, Neuroinflammation, Inflammation, Phosphoric Diester Hydrolases, MPTP, Brain, Mice, Inbred C57BL, 030104 developmental biology, chemistry, Quinolines, Pyrazoles, Microglia, 030217 neurology & neurosurgery
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2دورية أكاديمية
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3
المؤلفون: Yanke Zhang, Yun Li, Pengfei Fu, Shanshan Lu, Fei Xiao, Yong Yang, Yan Xiong, Qin Yang, Baobing Gao, Fangshuo Zheng, Xuefeng Wang
المصدر: Frontiers in Molecular Neuroscience
مصطلحات موضوعية: 0301 basic medicine, status epilepticus, Postsynaptic Current, rat model, Hippocampus, NR2A, Neurotransmission, Biology, Inhibitory postsynaptic potential, 03 medical and health sciences, Cellular and Molecular Neuroscience, 030104 developmental biology, 0302 clinical medicine, nervous system, Postsynaptic potential, Synaptic plasticity, Excitatory postsynaptic potential, PDE10A, Molecular Biology, Neuroscience, PF-2545920, 030217 neurology & neurosurgery, GluA1, Original Research
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المؤلفون: John F. Harms, Christopher J. Schmidt, Anne W. Schmidt, Caroline Proulx-Lafrance, Eric S. Marr, Michael L. Corman, Kari R. Fonseca, Frank S. Menniti, Douglas S. Chapin, Rebecca E. O’Connor, Jayvardhan Pandit, Xinjun Hou, Judith A. Suiciak, Spiros Liras, Frederick R. Nelson, Patrick Robert Verhoest
المصدر: Journal of Medicinal Chemistry. 52:5188-5196
مصطلحات موضوعية: Male, Models, Molecular, PF-2545920, Molecular model, Stereochemistry, In Vitro Techniques, Crystallography, X-Ray, Chemical synthesis, Rats, Sprague-Dawley, Mice, Structure-Activity Relationship, chemistry.chemical_compound, Dogs, Drug Discovery, Avoidance Learning, Animals, Humans, Structure–activity relationship, Mice, Knockout, Binding Sites, Molecular Structure, biology, Phosphoric Diester Hydrolases, Chemistry, Quinoline, Brain, Phosphodiesterase, Hydrogen Bonding, Rats, Macaca fascicularis, Enzyme inhibitor, Microsomes, Liver, Quinolines, Schizophrenia, biology.protein, Pyrazoles, Molecular Medicine, Female, PDE10A, Antipsychotic Agents, Protein Binding
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المؤلفون: Gary Gilmour, Ann Marie L. Ogden, Sally Loomis, Anthony J. Baucum, Teri L. Belecky-Adams, Jonathan M. Wilson, Kalpana M. Merchant
المصدر: Neuropharmacology. 99
مصطلحات موضوعية: Agonist, Male, medicine.medical_specialty, PF-2545920, medicine.drug_class, Phosphodiesterase Inhibitors, Mice, Transgenic, Medium spiny neuron, c-Fos, Rats, Sprague-Dawley, Cellular and Molecular Neuroscience, chemistry.chemical_compound, Random Allocation, Dopamine receptor D1, Dopamine receptor D2, Internal medicine, Basal ganglia, medicine, Haloperidol, Animals, Pharmacology, Neurons, biology, Dose-Response Relationship, Drug, Phosphoric Diester Hydrolases, Receptors, Dopamine D2, Receptors, Dopamine D1, Benzazepines, Mice, Inbred C57BL, Neostriatum, Dopamine D2 Receptor Antagonists, Endocrinology, nervous system, chemistry, Dopamine Agonists, biology.protein, Quinolines, Pyrazoles, Proto-Oncogene Proteins c-fos, medicine.drug
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6دورية أكاديمية
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7
المؤلفون: Michael A. Walker
المصدر: Drug Discovery Today. 15:79-79
مصطلحات موضوعية: Pharmacology, PF-2545920, chemistry.chemical_compound, chemistry, Stereochemistry, business.industry, Drug Discovery, Medicine, PDE10A, business