المؤلفون: Nguyen, Phong Quoc, Conesa, Christine, Rabut, Elise, Bragagnolo, Gabriel, Gouzerh, Célia, Fernández-Tornero, Carlos, Lesage, Pascale, Reguera, Juan, Acker, Joël

المساهمون: Architecture et fonction des macromolécules biologiques (AFMB), Aix Marseille Université (AMU)-Centre National de la Recherche Scientifique (CNRS)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE), Institut de Biologie Intégrative de la Cellule (I2BC), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris-Saclay-Centre National de la Recherche Scientifique (CNRS), Centro de Investigaciones Biológicas Margarita Salas, Génomes, biologie cellulaire et thérapeutiques (GenCellDi (U944 / UMR7212)), Collège de France (CdF (institution))-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Université Paris Cité (UPCité), Hopital Saint-Louis [AP-HP] (AP-HP), Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP), ANR-17-CE11-0025,INstruc,Etude structurale du mécanisme d'intégration des rétrotransposons de levure dans les gènes transcrits par l'ARN Polymérase III(2017), Génomes, biologie cellulaire et thérapeutiques (GenCellDi (UMR_S_944)), Collège de France (CdF (institution))-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Université de Paris (UP), Lesage, Pascale, Etude structurale du mécanisme d'intégration des rétrotransposons de levure dans les gènes transcrits par l'ARN Polymérase III - - INstruc2017 - ANR-17-CE11-0025 - AAPG2017 - VALID

المصدر: Journal of Biological Chemistry
Journal of Biological Chemistry, 2021, 297 (4), pp.101093. ⟨10.1016/j.jbc.2021.101093⟩
The Journal of Biological Chemistry
Journal of Biological Chemistry, American Society for Biochemistry and Molecular Biology, 2021, 297 (4), pp.101093. ⟨10.1016/j.jbc.2021.101093⟩

مصطلحات موضوعية: in vitro integration, Saccharomyces cerevisiae Proteins, NS, nonspecific nuclease activity, Retroelements, [SDV.BBM.BS] Life Sciences [q-bio]/Biochemistry, Molecular Biology/Structural Biology [q-bio.BM], Saccharomyces cerevisiae, yeast, [SDV.BBM.BM] Life Sciences [q-bio]/Biochemistry, Molecular Biology/Molecular biology, Protein Domains, ST, strand transfer activity, Pol III, RNA polymerase III, NTD, N-terminal domain, PFV, Prototype foamy virus, Pol II, RNA polymerase II, Integrases, [SDV.BBM.BS]Life Sciences [q-bio]/Biochemistry, Molecular Biology/Structural Biology [q-bio.BM], SAXS, small-angle X-ray scattering, Ty1, IN, integrase, [SDV.BBM.BM]Life Sciences [q-bio]/Biochemistry, Molecular Biology/Molecular biology, intrinsically disordered region, Recombinant Proteins, Intrinsically Disordered Proteins, dDNA, donor DNA, VLP, virus-like particle, RT, Reverse transcriptase, LTR, long terminal repeat, TEV, tobacco Etch virus, CTD, carboxy terminal domain, integrase, CCD, catalytic core domain, Research Article

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::752cd905cee6d9885a55819773773c7c
https://amu.hal.science/hal-03402697/file/pho1.pdf

المؤلفون: Anne M. Gardner, Yow Yong Tan, Richard Fishel, Kristine E. Yoder, Nathan D. Jones, Ryan K. Messer, Gayan Senavirathne, Randi M. Kotlar, Anthony J. Rabe

المصدر: The Journal of Biological Chemistry

مصطلحات موضوعية: bp, base pair, 0301 basic medicine, CIC, conserved intasome core, integration, Protomer, FRET, Förster resonance energy transfer, Biochemistry, Histones, chemistry.chemical_compound, Catalytic Domain, Nucleosome binding, biology, Chemistry, IN, integrase, Chromatin, Nucleosomes, Integrase, retrovirus, NPS, nucleosome positioning sequence, NED, amino terminal extension domain, prototype foamy virus, CCD, catalytic core domain, Research Article, Base pair, Virus Integration, TL, nucleosomes treated with trypsin to remove the histone tails, Genome, Viral, enzyme catalysis, Protein–protein interaction, FL, full length, Viral Proteins, 03 medical and health sciences, vDNA, viral DNA, Humans, Nucleosome, PFV, prototype foamy virus, ΔCTD, deletion of the CTD, Molecular Biology, PAGE, polyacrylamide gel electrophoresis, Integrases, 030102 biochemistry & molecular biology, ΔNTD, deletion of the NED and NTD, nucleosome, NTD, amino terminal domain, Cell Biology, CTD, carboxyl terminal domain, protein–protein interaction, 030104 developmental biology, DNA, Viral, biology.protein, Biophysics, Spumavirus, Protein Multimerization, DNA

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c0972a0bff672c3b59ec64ad9561804f
https://doi.org/10.1016/j.jbc.2021.100550

المؤلفون: Balasubramanian S; a Centre for Bioinformatics, School of Life Sciences , Pondicherry University , Puducherry 605014 , India., Rajagopalan M; a Centre for Bioinformatics, School of Life Sciences , Pondicherry University , Puducherry 605014 , India., Bojja RS; b Institute for Cancer Research , Fox Chase Cancer Center , Philadelphia , PA 19111 , USA., Skalka AM; b Institute for Cancer Research , Fox Chase Cancer Center , Philadelphia , PA 19111 , USA., Andrake MD; b Institute for Cancer Research , Fox Chase Cancer Center , Philadelphia , PA 19111 , USA., Ramaswamy A; a Centre for Bioinformatics, School of Life Sciences , Pondicherry University , Puducherry 605014 , India.

المصدر: Journal of biomolecular structure & dynamics [J Biomol Struct Dyn] 2017 Dec; Vol. 35 (16), pp. 3469-3485. Date of Electronic Publication: 2016 Nov 28.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Taylor & Francis Country of Publication: England NLM ID: 8404176 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1538-0254 (Electronic) Linking ISSN: 07391102 NLM ISO Abbreviation: J Biomol Struct Dyn Subsets: MEDLINE

مواضيع طبية MeSH: Molecular Dynamics Simulation* , Protein Multimerization*, Avian Sarcoma Viruses/*chemistry , HIV Integrase/*chemistry , HIV-1/*chemistry, Amino Acid Motifs ; Avian Sarcoma Viruses/enzymology ; Catalytic Domain ; Crystallography, X-Ray ; HIV-1/enzymology ; Kinetics ; Protein Binding ; Protein Conformation, alpha-Helical ; Protein Conformation, beta-Strand ; Protein Interaction Domains and Motifs ; Thermodynamics