المؤلفون: Kouichi Kitamura, Tyuji Hoshino, Atsushi Okabe, Masaki Fukuyo, Bahityar Rahmutulla, Nobuko Tanaka, Sohei Kobayashi, Tomoaki Tanaka, Takashi Shida, Mashiro Ueda, Toshinari Minamoto, Hisahiro Matsubara, Atsushi Kaneda, Hideshi Ishii, Kazuyuki Matsushita

المصدر: International Journal of Molecular Sciences, Vol 24, Iss 24, p 17341 (2023)

مصطلحات موضوعية: FUBP1-interacting repressor (FIR), aberrant RNA splicing, ribosomal RNA (rRNA), RPB6 of RNA polymerase (RNAP), transcription factor IIH (TFIIH) P62 PH (pleckstrin homology), Biology (General), QH301-705.5, Chemistry, QD1-999

وصف الملف: electronic resource

Relation: https://www.mdpi.com/1422-0067/24/24/17341; https://doaj.org/toc/1661-6596; https://doaj.org/toc/1422-0067

URL الوصول: https://doaj.org/article/a0cff5f04aac422ea084b85f427bed9b

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المؤلفون: Chun-Jung Lin, Jer Tsong Hsieh, Andrew Dang, Elizabeth Hernandez

المصدر: Neoplasia: An International Journal for Oncology Research, Vol 23, Iss 1, Pp 169-180 (2021)
Neoplasia (New York, N.Y.)

مصطلحات موضوعية: 0301 basic medicine, WT, wild type, Cancer Research, Kinesins, Con, vector control, medicine.disease_cause, Mice, 0302 clinical medicine, Primary cilia, DAB2IP, DAB2 Interacting Protein, C2, protein kinase C conserved region 2 domain, PH, Pleckstrin homology domain, DAPI, 4’, 6-diamidino-2-phenylindole, Tumor suppressor gene, ac-tubulin, acetylated tubulin, STR, short tandem repeat, Kidney, qRT-PCR, Quantitative real-time PCR, Cilium, lcsh:Neoplasms. Tumors. Oncology. Including cancer and carcinogens, Kidney Neoplasms, Renal cell carcinoma, Cell biology, medicine.anatomical_structure, Cell Transformation, Neoplastic, UTSW, University of Texas Southwestern Medical Center, ras GTPase-Activating Proteins, 030220 oncology & carcinogenesis, Kinesin, RCC, renal cell carcinoma, Disease Susceptibility, Protein Binding, Original article, AIG, anchorage independent growth assay, Biology, lcsh:RC254-282, DAB2IP, Cell Line, 03 medical and health sciences, FBS, fetal bovine serum, Microtubule, Ciliogenesis, medicine, Animals, Humans, KIF3A, Cilia, KD, knockdown, KO, knockout, ATCC, American Type Culture Collection, VHL, von Hippel-Lindau, 030104 developmental biology, TCGA, The Cancer Genome Atlas, HIF, hypoxia-inducible factors, KIF3a, kinesin family member 3A, Carcinogenesis, KIF3a, IFT, intraflagellar transport, Protein Processing, Post-Translational, OE, overexpression

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::361470a71f476fd73c328cb0a2367cb3
http://www.sciencedirect.com/science/article/pii/S1476558620301834

المؤلفون: Akhil Padarti, Ofek Belkin, Johnathan Abou-Fadel, Jun Zhang

المصدر: Biochemistry and Biophysics Reports
Biochemistry and Biophysics Reports, Vol 29, Iss, Pp 101218-(2022)

مصطلحات موضوعية: POLYPHEN-2, Polymorphism Phenotyping, Amino acid substitution, QH301-705.5, Short Communication, PTB, phosphotyrosine binding, PH, pleckstrin homology, CUPSAT, Cologne University Protein Stability Analysis Tool, Biophysics, PTCs, premature termination codons, QD415-436, macromolecular substances, INDELs, insertions/deletions, PANTHER, Protein ANalysis THrough Evolutionary Relationship, MAF, minor allele frequency, Biochemistry, environment and public health, PROVEAN, Protein Variation Effect Analyzer, Tertiary structure, I-TASSER, the iterative threading assembly refinement, Biology (General), PDB, protein data bank, CCMs, cerebral cavernous malformations, HOPE, Have (y)Our Protein Explained, integumentary system, Single nucleotide polymorphisms (SNPs), SIFT, Sorting Intolerant From Tolerant, CSC, CCM signaling complex, Nonsynonymous single nucleotide polymorphisms (nsSNPs), In-silico analysis, Superimposition of protein structures, nsSNP, nonsynonymous single nucleotide polymorphism

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef96d23ace56c6f3462edfb27158ca35
http://europepmc.org/articles/PMC8808078

المؤلفون: Sukhamoy Gorai, Ha Pham, Pawanthi Buwaneka, Arthur Ralko, Wonhwa Cho

المصدر: The Journal of Biological Chemistry

مصطلحات موضوعية: Phosphatidylinositol 4,5-Diphosphate, WT, wild type, Phosphatidylinositol 3,4-bisphosphate, Receptor complex, GAPDH, glyceraldehyde 3-phosphate dehydrogenase, Receptor, Transforming Growth Factor-beta Type I, PI(3)P, phosphatidylinositol-3-phosphate, SMAD, Smad2 Protein, Biochemistry, EGFP, enhanced green fluorescence protein, TIRF, total internal reflection fluorescence, chemistry.chemical_compound, PI(4,5)P2, MH2 domain, Transforming Growth Factor beta, PLCδ, phospholipase Cδ, siRNA, short interference RNA, TMR, tetramethylrhodamine, Receptor, PH, pleckstrin homology domain, FRB, FKBP12-rapamycin binding domain of mTOR, POPC, 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine, Cell biology, POPS, 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphoserine, Phosphatidylinositol 4,5-bisphosphate, PIP3, phosphatidylinositol-3,4,5-bisphosphate, PM, plasma membrane, Phosphorylation, SARA, Smad anchor for receptor activation, Signal transduction, Protein Binding, Signal Transduction, Research Article, TβR, transforming growth factor-β receptor, Active Transport, Cell Nucleus, SPR, surface plasmon resonance, LUVs, large unilamellar vesicles, TGF-β, transforming growth factor-β, Humans, EEs, early endosomes, Molecular Biology, membrane-protein interaction, PI(3,4)P2, phosphatidylinositol-3,4-bisphosphate, Phosphatidylinositol 3-phosphate, PtdInsP, phosphoinositide, Cell Biology, TGF-b, TGF-b receptor, chemistry, PI(4,5)P2, phosphatidylinositol-4,5-bisphosphate, plasma membrane targeting, FKBP12, 12 kDa FK506-binding protein, MH, Mad homology, Smad2, HeLa Cells

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef605ebedf237cc470093be8d892be72
https://pubmed.ncbi.nlm.nih.gov/34655614

المؤلفون: Andrea Papdine Morovicz, Sandra Ninzima, Diana Cornelia Turcu, Malene Skuseth Slinning, Clive D'Santos, Aurélia E. Lewis, Fatemeh Mazloumi Gavgani, Victoria Smith Arnesen

المصدر: Molecular & Cellular Proteomics : MCP
Molecular & Cellular Proteomics

مصطلحات موضوعية: Phosphatidylinositol 3,4-bisphosphate, Phosphatidylinositol 4-phosphate, Nucleolus, interactome, PtdIns, phosphatidylinositols, Biochemistry, Interactome, Analytical Chemistry, chemistry.chemical_compound, Phosphatidylinositol Phosphates, GRP1, general receptor of phosphoinositides-1, HRP, horse radish peroxidase, PA, phosphatidic acid, Protein Interaction Maps, SILAC, stable isotope labeling with amino acids in cell culture, 0303 health sciences, Chemistry, 030302 biochemistry & molecular biology, ZnF, zinc finger, BRCT, BRCA1 C terminus, Cell biology, phosphoinositide, WGR, Trp-Gly-Arg domain, Pleckstrin homology domain, Phosphatidylinositol 4,5-bisphosphate, PPIn, polyphosphoinositide, PI3K, phosphoinositide 3-kinase, IQGAP1, IQ motif containing GTPase-activating proteins, PBS-T, PBS containing 0.05% Tween-20, PH, pleckstrin homology, PBRs, polybasic regions, PARP1, poly(ADP-ribose) polymerase 1, phosphatidylinositol 3,4,5-trisphosphate, Chromatin remodeling, OGT, O-linked N-acetylglucosamine transferase 110-kDa subunit, 03 medical and health sciences, PtdIns(3,4)P2, phosphatidylinositol 3,4-bisphosphate, HSPs, heat-shock proteins, Humans, nucleolus, Molecular Biology, polybasic region, 030304 developmental biology, GO, gene ontology, Cell Nucleus, PtdIns(3,4,5)P3, phosphatidylinositol 3,4,5-trisphosphate, Phosphatidylinositol (3,4,5)-trisphosphate, Research, SHIP, Src homology 2 domain–containing inositol phosphatase, PtdIns(4,5)P2, phosphatidylinositol 4,5-bisphosphate, EBP1, ErbB3-binding protein 1, PtdIns4P, phosphatidylinositol 4-phosphate, HeLa Cells

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::681700c62f516155bf3f4f055966ecfe
http://europepmc.org/articles/PMC8255942

المؤلفون: Juan Darío Ortigoza-Escobar, Norito Tamura, Asako Goto, Kentaro Hanada, Shota Sakai, Roser Colomé, Aya Mizuike, Loreto Martorell

المصدر: The Journal of Biological Chemistry

مصطلحات موضوعية: medicine.disease_cause, Biochemistry, CERT, ceramide transport protein, chemistry.chemical_compound, mVenus, monomeric Venus, hGH, human growth hormone, CRISPR, clustered regularly interspaced short palindromic repeat, Phosphorylation, ceramide transport protein, ID, intellectual disability, PtdIns(4)P, phosphatidylinositol 4-monophosphate, Mutation, Cas9, CRISPR-associated protein 9, FFAT, two phenylalanines in an acidic tract, HRP, horseradish peroxidase, Ceramide transport, Cell biology, Sphingomyelins, Protein Transport, KI, knockin, symbols, START, steroidogenic acute regulatory protein-related lipid transfer, Sphingomyelin, Research Article, Ceramide, GlcCer, glucosylceramide, PH, pleckstrin homology, Mutation, Missense, Hyperphosphorylation, Protein Serine-Threonine Kinases, GalCer, galactosylceramide, SEM, standard error of the mean, Frameshift mutation, sphingomyelin, ER, endoplasmic reticulum, VAP, vesicle-associated membrane protein-associated protein, symbols.namesake, lipidome, Intellectual Disability, medicine, Humans, Molecular Biology, SV40, simian virus 40, GM130, Golgi matrix protein 130, KO, knockout, SM, sphingomyelin, Endoplasmic reticulum, Cell Biology, Golgi apparatus, MLPA, multiplex ligation-dependent probe amplification analysis, SRM, serine-repeat motif, chemistry, Amino Acid Substitution, SD, standard deviation, HA, hemagglutinin

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d92f6bd36e355923c0feb4eaa7d7a4b
https://pubmed.ncbi.nlm.nih.gov/34688657

المؤلفون: Yan Yuan Tseng, Wei Sheng Wu, Chien Sheng Chen, Biqing Liang, Jagat Rathod, Han-Chen Yen

المصدر: Computational and Structural Biotechnology Journal
Computational and Structural Biotechnology Journal, Vol 19, Iss, Pp 3692-3707 (2021)

مصطلحات موضوعية: PI3P, phosphatidylinositol-3-phosphate, PI4P, phosphatidylinositol-4-phosphate, S. cerevisiae, LRD, Lipid-Related Domain, ITC, Isothermal Titration Calorimetry, PI5P, phosphatidylinositol-5-phosphate, Biochemistry, Interactome, OSBP, Oxysterol-Binding Protein, chemistry.chemical_compound, 0302 clinical medicine, LMPD, LIPID MAPS Proteome Database, Structural Biology, PtdIns, Phosphatidylinositol, LBD, Lipid-Binding Domain, 0303 health sciences, PIs, Phosphoinositides, Lipid-binding domain, Computer Science Applications, Transport protein, Cvt, Cytoplasm-to-vacuole targeting, 030220 oncology & carcinogenesis, QCM, Quartz Crystal Microbalance, BAR, Bin-Amphiphysin-Rvs, LMSD, LIPID MAPS Structure Database, Biotechnology, FYVE, Fab 1 (yeast orthologue of PIKfyve), YOTB, Vac 1 (vesicle transport protein), and EEA1, OMIM, Online Mendelian Inheritance in Man, Phosphoinositides (PIs), SNX, Sorting Nexin, SPR, Surface Plasmon Resonance, Protein domain, Phosphatidylinositol (PtdIns), Biophysics, CAFA, Critical Assessment of Functional Annotation, PX, Phox Homology, Computational biology, Biology, Domain (software engineering), 03 medical and health sciences, Interaction network, PH, Pleckstrin Homology, GO, Gene Ontology, Genetics, Phosphatidylinositol, 030304 developmental biology, ComputingMethodologies_COMPUTERGRAPHICS, Data Article, FDR, False Discovery Rate, ANTH, AP180 N-terminal Homology, PI(3,4)P2, phosphatidylinositol-3,4-bisphosphate, PI(3,5)P2, phosphatidylinositol-3,5-bisphosphate, PMID, PubMed ID, Phosphoinositide binding, YPIBP, Yeast Phosphoinositide-Binding Proteins, Yeast, PI-binding protein, chemistry, ENTH, Epsin N-terminal Homology, PI(4,5)P2, phosphatidylinositol-4,5-bisphosphate, CRAL-TRIO, cellular retinaldehyde-binding protein (CRALBP) and TRIO guanine exchange factor, PI(3,4,5)P3, phosphatidylinositol-3,4,5-trisphosphate, TP248.13-248.65

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9fb2a67a1c3142c2aef0b9fab10457ce
https://pubmed.ncbi.nlm.nih.gov/34285772

المؤلفون: Nada Bulus, Charles R. Sanders, Ambra Pozzi, Glenda Mernaugh, Anika Böttcher, Xinyu Dong, Reinhard Fässler, Roy Zent, Kyle L. Brown

المصدر: Journal of Biological Chemistry
The Journal of Biological Chemistry
J. Biol. Chem. 296:100361 (2021)

مصطلحات موضوعية: IPP, ILK–pinch–parvin, Male, CD, collecting duct, Kidney development, Kidney, Cell morphology, Biochemistry, Mice, 0302 clinical medicine, Mice, Knockout, 0303 health sciences, biology, medicine.diagnostic_test, Chemistry, Microfilament Proteins, PBS, paxillin-binding site, LIM Domain Proteins, MD, molecular dynamics, ILK, integrin-linked kinase, Cell biology, Pleckstrin homology domain, embryonic structures, Female, Research Article, PH, pleckstrin homology, DMEM, Dulbecco's minimal essential media, Molecular Dynamics Simulation, Protein Serine-Threonine Kinases, Cell Line, 03 medical and health sciences, Protein Domains, Western blot, Cell Adhesion, medicine, Animals, Integrin-linked kinase, Cell adhesion, Molecular Biology, Adaptor Proteins, Signal Transducing, 030304 developmental biology, cell culture, Focal Adhesions, western blot, molecular modeling, Membrane Proteins, PC, principal component, Cell Biology, molecular dynamics, Mice, Inbred C57BL, Cell culture, biology.protein, Paxillin, 030217 neurology & neurosurgery

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad61ae4ef7134c8112c643b4b35e5fcc

المؤلفون: Raju V. S. Rajala

المصدر: Journal of Lipid Research, Vol 62, Iss, Pp 100041-(2021)
Journal of Lipid Research

مصطلحات موضوعية: 0301 basic medicine, PI(3,4) P2, phosphatidylinositol 3,4-bisphosphate, IGF, insulin-like growth factor, PIKfyve, FYVE-type zinc finger containing phosphoinositide kinase, 030204 cardiovascular system & hematology, Phosphatidylinositols, Biochemistry, PDGF, platelet-derived growth factor, chemistry.chemical_compound, PTP1B, protein tyrosine phosphatase 1B, 0302 clinical medicine, Endocrinology, SHIP, Src homology 2 domain-containing inositol polyphosphate 5-phosphatase, phosphoinositide binding proteins, PI(4,5)P2, phosphatidylinositol 4,5-bisphosphate, biology, Grb14, growth factor receptor-bound protein 14, phosphoinositide kinases, PI(5)P, phosphatidylinositol 5-phosphate, PIPK, phosphatidylinositol phosphate kinase, PITP, phosphatidylinositol transfer protein, Cell biology, Pleckstrin homology domain, PI4K, phosphatidylinositol 4-kinase, OCRL, oculocerebrorenal syndrome of Lowe, Phosphatidylinositol 4,5-bisphosphate, PI(3)P, phosphatidylinositol 3-phosphate, IR, insulin receptor, PI(3,5)P2, phosphatidylinositol 3,5-bisphosphate, VDAC, voltage-dependent anion channel, IRS, insulin receptor substrate, lipids (amino acids, peptides, and proteins), PIP, phosphatidylinositol phosphate, IP3, inositol triphosphate, light activation, PI3K, phosphoinositide 3-kinase, SH2, Src homology 2, CNTF, ciliary neurotrophic factor, TRP, transient receptor potential, Thematic Review Series: Seeing 2020: Lipids and Lipid-Soluble Molecules in the Eye, musculoskeletal diseases, Phosphatidylinositol 3,5-bisphosphate, RPE, retinal pigment epithelium, CNGA1, cyclic nucleotidegated channel subunit α1, PH, pleckstrin homology, Vps, vacuolar protein sorting, mTOR, mammalian target of rapamycin, QD415-436, PI, phosphatidylinositol, Phosphoinositide Phosphatases, INPP5, inositol polyphosphate 5-phosphatase, 03 medical and health sciences, FYCO1, FYVE and coiled-coil domain autophagy adaptor 1, PLC, phospholipase C, GSK3β, glycogen synthase kinase 3β, PKC, protein kinase C, ROS, rod outer segment, Phosphatidylinositol 5-phosphate, GPCR, G protein-coupled receptor, CNG, cyclic nucleotide-gated, Phosphoinositide 3-kinase, Phosphatidylinositol (3,4,5)-trisphosphate, Phosphatidylinositol 3-phosphate, fungi, PI(4)P, phosphatidylinositol 4-phosphate, Thematic Review Series, phosphoinositide phosphatases, Cell Biology, PTEN, phosphatase and tensin homolog, PI(3,4,5)P2, phosphatidylinositol 3,4,5-trisphosphate, body regions, 030104 developmental biology, chemistry, biology.protein, EPO, erythropoietin, RA, Ras-associating

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ad76a0de070275a6dd0bb666e2b0f8c
http://www.sciencedirect.com/science/article/pii/S0022227521000213