المؤلفون: Erin E. Drufva, Constance B. Bailey, Elijah G. Hix

المصدر: Synthetic and Systems Biotechnology, Vol 5, Iss 2, Pp 62-80 (2020)
Synthetic and Systems Biotechnology

مصطلحات موضوعية: 0106 biological sciences, ER, enoylreductase, ACP, acyl carrier protein, Mod, module, Computer science, lcsh:Biotechnology, Biomedical Engineering, Mutagenesis (molecular biology technique), Computational biology, 01 natural sciences, Applied Microbiology and Biotechnology, Article, 03 medical and health sciences, Polyketide, Synthetic biology, EI, enoylisomerase, MT, methyltransferase, LM, loading module, Structural Biology, KS, ketosynthase, lcsh:TP248.13-248.65, 010608 biotechnology, Polyketide synthase, Genetics, AT, acyltransferase, PS, pyran synthase, Site-directed mutagenesis, Saturated mutagenesis, lcsh:QH301-705.5, 030304 developmental biology, Saturation mutagenesis, 0303 health sciences, biology, DEBS, 6-deoxyerthronolide B synthase, Rational design, Protein engineering, SNAC, N-acetyl cysteamine, lcsh:Biology (General), biology.protein, PKS, polyketide synthase, KR, ketoreductase, DH, dehydratase, Site directed mutagenesis

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b84c5447c1f65c695a30aae495cef9d
https://doi.org/10.1016/j.synbio.2020.04.001

المؤلفون: Swarnmala Samal, Mukesh Meena

المصدر: Toxicology Reports
Toxicology Reports, Vol 6, Iss, Pp 745-758 (2019)

مصطلحات موضوعية: HSTs, host specific toxins, Health, Toxicology and Mutagenesis, Alternariol, 010501 environmental sciences, ALT, alternuene, Toxicology, CDCs, conditionally dispensable chromosomes, 01 natural sciences, chemistry.chemical_compound, 0302 clinical medicine, GPX, guaiacol peroxidase, GSH, glutathione, GR, glutathione reductase, PCD, programmed cell death, ˙OH, hydroxyl radical, DHT, dihydrotentoxin, HR, hypersensitive response, biology, SMs, secondary metabolites, food and beverages, Plant physiology, Alternaria, AOH, alternariol, Biochemistry, H2O2, hydrogen peroxide, APX, ascorbate peroxidase, 1O2, singlet oxygen, UGT, UDP-Glucuronosyltransferases, Membrane permeability, Host-specific toxins, DHAR, dehydroascorbate reductase, TeA, tenuazonic acid, Article, 03 medical and health sciences, ROS, reactive oxygen species, lcsh:RA1190-1270, SOD, superoxide dismutase, PKS, polyketide synthase gene, otorhinolaryngologic diseases, Tenuazonic acid, Pathogenicity, O2˙ˉ, superoxide anion, Mycotoxin, lcsh:Toxicology. Poisons, 0105 earth and related environmental sciences, ComputingMethodologies_COMPUTERGRAPHICS, ATX, alterotoxin, NO, nitric oxide, Secondary metabolites, NRPS, nonribosomal peptide synthetase, Curvularin, Alternaria species, biology.organism_classification, TEN, tentoxin, MDHAR, monodehydroascorbate reductase, chemistry, Tentoxin, AME, alternariol 9-monomethyl ether, AA, ascorbic acid, CAT, catalase, nHSTs, non-host specific toxins, Non-host-specific toxins, 030217 neurology & neurosurgery, REMI, restriction enzyme-mediated integration

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::487c975b3848480f404e9814d65eba01
http://europepmc.org/articles/PMC6684332

المؤلفون: Constance B. Bailey, Jesus F. Barajas, Samuel C. Curran, Jacquelyn M. Blake-Hedges, Jay D. Keasling

المصدر: Synthetic and Systems Biotechnology, Vol 2, Iss 3, Pp 147-166 (2017)
Synthetic and Systems Biotechnology
Synthetic and systems biotechnology, vol 2, iss 3
Barajas, J F, Blake-Hedges, J M, Bailey, C B, Curran, S & Keasling, J D 2017, ' Engineered polyketides: Synergy between protein and host level engineering ', Synthetic and Systems Biotechnology, vol. 2, no. 3, pp. 147-166 . https://doi.org/10.1016/j.synbio.2017.08.005
Barajas, JF; Blake-Hedges, JM; Bailey, CB; Curran, S; & Keasling, JD. (2017). Engineered polyketides: Synergy between protein and host level engineering. Synthetic and Systems Biotechnology, 2(3), 147-166. doi: 10.1016/j.synbio.2017.08.005. Lawrence Berkeley National Laboratory: Retrieved from: http://www.escholarship.org/uc/item/6908v16f

مصطلحات موضوعية: 0301 basic medicine, PK, Engineering, Commodity chemicals, TE, Thioesterase, DH, R, Reductase domain, Precursor directed biosynthesis, 01 natural sciences, Applied Microbiology and Biotechnology, DE, LM, CoL, CoA-Ligase, Synthetic biology, Commodity chemical, Structural Biology, Dehydratase, PK, Polyketide, Streptomyces antibiotic regulatory protein, lcsh:QH301-705.5, Ketoreductase, Natural products, PCC, biology, Dimerization element, TKL, PKS, PKS, Polyketide synthase, LysR-type transcriptional regulator, SARP, Streptomyces antibiotic regulatory protein, CoL, Reductase domain, KS, KR, DEBS, 6-deoxyerythronolide B synthase, ER, Enoylreductase, PCC, Propionyl-CoA carboxylase, SNAC, TE, PDB, Fatty acid synthases, Acyltransferase, N-acetylcysteamine, lcsh:Biotechnology, CoA-Ligase, Biomedical Engineering, FAS, Fatty acid synthases, Bioengineering, Nanotechnology, Computational biology, 6-deoxyerythronolide B synthase, Cellular level, Polyketide, Article, AT, Acyltransferase, DE, Dimerization element, LM, Loading module, Metabolic engineering, 03 medical and health sciences, lcsh:TP248.13-248.65, Polyketide synthase, PDB, Precursor directed biosynthesis, Genetics, Acyl carrier protein, SNAC, N-acetylcysteamine, ACP, KS, Ketosynthase, Triketide lactone, TKL, Triketide lactone, 010405 organic chemistry, business.industry, Propionyl-CoA carboxylase, Thioesterase, DEBS, FAS, Loading module, SARP, LTTR, LysR-type transcriptional regulator, 0104 chemical sciences, 030104 developmental biology, ER, DH, Dehydratase, lcsh:Biology (General), Chemical diversity, biology.protein, Ketosynthase, KR, Ketoreductase, AT, ACP, Acyl carrier protein, LTTR, business, Enoylreductase

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::434d695113b544867aef42aadbfb2c86
https://doi.org/10.1016/j.synbio.2017.08.005

المؤلفون: Callie E.W. Crawford, Rebecca S. Koweek, Louise K. Charkoudian, Ariana Sulpizio

المصدر: The Journal of Biological Chemistry

مصطلحات موضوعية: 0301 basic medicine, ACP, acyl carrier protein, Protein Conformation, Biochemistry, FT-ICR-MS, Fourier-transform ion cyclotron resonance mass spectrometry, chemistry.chemical_compound, polyketide, KS, ketosynthase, Iga11, ketosynthase from the ishigamide highly reducing polyketide synthase, HR, highly reducing, biology, Chemistry, Oxy, oxygenase, BGC, biosynthetic gene cluster, FAS, fatty acid synthase, Acyl carrier protein, FabF, β-ketoacyl synthase from the E. coli fatty acid synthase, 6-Deoxyerythronolide B synthase, DEBS, 6-deoxyerythronolide B synthase, PKS, polyketide synthase, lipids (amino acids, peptides, and proteins), Phosphopantetheine, DH, dehydratase, Protein Binding, protein crosslinking, CoA, coenzyme A, Iga, ishigamide, Coenzyme A, Reviews, acyl carrier protein (ACP), Computational biology, Protein–protein interaction, Structure-Activity Relationship, 03 medical and health sciences, Polyketide, Ppant, phosphopantetheine, Polyketide synthase, Acyl Carrier Protein, PPTase, phosphopantetheinyl transferase, Amino Acid Sequence, Molecular Biology, Adenylylation, PCP, peptidyl carrier protein, FabA, dehydratase from the E. coli fatty acid synthase, Sequence Homology, Amino Acid, 030102 biochemistry & molecular biology, NRPS, nonribosomal peptide synthetase, Iga10, acyl carrier protein from the ishigamide highly reducing polyketide synthase, Cell Biology, KSCLF, ketosynthase chain length factor, Biosynthetic Pathways, AntD, ketosynthase from the Photorhabdus luminescens anthraquinone polyketide synthase, AntF, acyl carrier protein from the Photorhabdus luminescens anthraquinone polyketide synthase, 030104 developmental biology, Molecular Probes, Polyketides, A, adenylation, biology.protein, CLF, chain length factor, fatty acid, biosynthesis, KR, ketoreductase, AcpP, acyl carrier protein from the E. coli fatty acid synthase, Polyketide Synthases

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a2ebfbedbbc3ac250ea6ebab0a8b3676
https://doi.org/10.1016/j.jbc.2021.100328

المؤلفون: Chad W, Johnston, Jonathan, Plumb, Xiang, Li, Sergio, Grinstein, Nathan A, Magarvey

المصدر: Synthetic and Systems Biotechnology

مصطلحات موضوعية: Natural products, PCA, principal component analysis, PRISM, MS, mass spectrometry, LC, liquid chromatography, Polyketides, NRPS, nonribosomal peptide synthetase, Legionella, PKS, polyketide synthase, Article

URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid________::a605666b7e0532486f97d6b7b0ca0235
https://pubmed.ncbi.nlm.nih.gov/29062936

المؤلفون: Hyun Uk Kim, Tilmann Weber

المصدر: Weber, T & Kim, H U 2016, ' The secondary metabolite bioinformatics portal : Computational tools to facilitate synthetic biology of secondary metabolite production ', Synthetic and Systems Biotechnology, vol. 1, no. 2, pp. 69-79 . https://doi.org/10.1016/j.synbio.2015.12.002
Synthetic and Systems Biotechnology
Synthetic and Systems Biotechnology, Vol 1, Iss 2, Pp 69-79 (2016)

مصطلحات موضوعية: 0301 basic medicine, RiPP, ribosomally and post-translationally modified peptide, Bioinformatics, lcsh:Biotechnology, Biomedical Engineering, PK, polyketide, Context (language use), Genomics, Biology, Biosynthesis, Applied Microbiology and Biotechnology, Article, Field (computer science), Natural product, Omics data, 03 medical and health sciences, Synthetic biology, Lead (geology), Structural Biology, Antibiotics, lcsh:TP248.13-248.65, Genetics, A, adenylation domain, NMR, nuclear magnetic resonance, lcsh:QH301-705.5, PCP, peptidyl carrier protein, C, condensation domain, GPR, gene-protein-reaction, SVM, support vector machine, 030102 biochemistry & molecular biology, LC, liquid chromatography, Drug discovery, NRPS, PKS, BGC, biosynthetic gene cluster, NRP, non-ribosomally synthesized peptide, 030104 developmental biology, lcsh:Biology (General), MS, mass spectrometry, HMM, hidden Markov model, NRPS, non-ribosomal peptide synthetase, Paradigm shift, PKS, polyketide synthase

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::17041a513e80564eabcd137ba9148a69

المؤلفون: Mohite OS; The Novo Nordisk Foundation Center for Biosustainability, Technical University of Denmark, Kongens Lyngby, 2800, Denmark., Lloyd CJ; Department of Bioengineering, University of California San Diego, La Jolla, CA, 92093, USA., Monk JM; Department of Bioengineering, University of California San Diego, La Jolla, CA, 92093, USA., Weber T; The Novo Nordisk Foundation Center for Biosustainability, Technical University of Denmark, Kongens Lyngby, 2800, Denmark., Palsson BO; The Novo Nordisk Foundation Center for Biosustainability, Technical University of Denmark, Kongens Lyngby, 2800, Denmark.; Department of Bioengineering, University of California San Diego, La Jolla, CA, 92093, USA.

المصدر: Synthetic and systems biotechnology [Synth Syst Biotechnol] 2022 May 06; Vol. 7 (3), pp. 900-910. Date of Electronic Publication: 2022 May 06 (Print Publication: 2022).

نوع المنشور: Journal Article

بيانات الدورية: Publisher: KeAi Communications Co Country of Publication: China NLM ID: 101694371 Publication Model: eCollection Cited Medium: Internet ISSN: 2405-805X (Electronic) Linking ISSN: 2405805X NLM ISO Abbreviation: Synth Syst Biotechnol Subsets: PubMed not MEDLINE

المؤلفون: Pérez J; Departamento de Microbiología, Facultad de Ciencias, Avda. Fuentenueva s/n, Universidad de Granada, 18071 Granada, Spain., Contreras-Moreno FJ; Departamento de Microbiología, Facultad de Ciencias, Avda. Fuentenueva s/n, Universidad de Granada, 18071 Granada, Spain., Marcos-Torres FJ; Department of Cell and Molecular Biology, Uppsala University, Uppsala 751 24, Sweden., Moraleda-Muñoz A; Departamento de Microbiología, Facultad de Ciencias, Avda. Fuentenueva s/n, Universidad de Granada, 18071 Granada, Spain., Muñoz-Dorado J; Departamento de Microbiología, Facultad de Ciencias, Avda. Fuentenueva s/n, Universidad de Granada, 18071 Granada, Spain.

المصدر: Computational and structural biotechnology journal [Comput Struct Biotechnol J] 2020 Sep 15; Vol. 18, pp. 2547-2555. Date of Electronic Publication: 2020 Sep 15 (Print Publication: 2020).

نوع المنشور: Journal Article; Review

بيانات الدورية: Publisher: Elsevier B.V. on behalf of Research Network of Computational and Structural Biotechnology Country of Publication: Netherlands NLM ID: 101585369 Publication Model: eCollection Cited Medium: Print ISSN: 2001-0370 (Print) Linking ISSN: 20010370 NLM ISO Abbreviation: Comput Struct Biotechnol J Subsets: PubMed not MEDLINE

المؤلفون: Drufva EE; Department of Chemistry, University of Tennessee-Knoxville, Knoxville, TN, 37996, USA., Hix EG; Department of Chemistry, University of Tennessee-Knoxville, Knoxville, TN, 37996, USA., Bailey CB; Department of Chemistry, University of Tennessee-Knoxville, Knoxville, TN, 37996, USA.

المصدر: Synthetic and systems biotechnology [Synth Syst Biotechnol] 2020 May 13; Vol. 5 (2), pp. 62-80. Date of Electronic Publication: 2020 May 13 (Print Publication: 2020).

نوع المنشور: Journal Article; Review

بيانات الدورية: Publisher: KeAi Communications Co Country of Publication: China NLM ID: 101694371 Publication Model: eCollection Cited Medium: Internet ISSN: 2405-805X (Electronic) Linking ISSN: 2405805X NLM ISO Abbreviation: Synth Syst Biotechnol Subsets: PubMed not MEDLINE

المؤلفون: Meena M; Department of Botany, University College of Science, Mohanlal Sukhadia University, Udaipur, 313001, India.; Centre of Advanced Study in Botany, Institute of Science, Banaras Hindu University, Varanasi, 221005, India., Samal S; Centre of Advanced Study in Botany, Institute of Science, Banaras Hindu University, Varanasi, 221005, India.

المصدر: Toxicology reports [Toxicol Rep] 2019 Jul 17; Vol. 6, pp. 745-758. Date of Electronic Publication: 2019 Jul 17 (Print Publication: 2019).

نوع المنشور: Journal Article; Review

بيانات الدورية: Publisher: Elsevier Ireland Ltd Country of Publication: Ireland NLM ID: 101630272 Publication Model: eCollection Cited Medium: Internet ISSN: 2214-7500 (Electronic) Linking ISSN: 22147500 NLM ISO Abbreviation: Toxicol Rep Subsets: PubMed not MEDLINE