المؤلفون: Wu P; Traditional Chinese Medicine Integrated Department of Nephrology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, People's Republic of China.; Institute of Nephrology, Zhengzhou University, Zhengzhou, People's Republic of China.; Henan Province Research Center for Kidney Disease, Zhengzhou, People's Republic of China.; Key Laboratory of Precision Diagnosis and Treatment for Chronic Kidney Disease in Henan Province, Zhengzhou, People's Republic of China., Li ST; Traditional Chinese Medicine Integrated Department of Nephrology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, People's Republic of China.; Institute of Nephrology, Zhengzhou University, Zhengzhou, People's Republic of China.; Henan Province Research Center for Kidney Disease, Zhengzhou, People's Republic of China.; Key Laboratory of Precision Diagnosis and Treatment for Chronic Kidney Disease in Henan Province, Zhengzhou, People's Republic of China., Shu TT; Traditional Chinese Medicine Integrated Department of Nephrology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, People's Republic of China.; Institute of Nephrology, Zhengzhou University, Zhengzhou, People's Republic of China.; Henan Province Research Center for Kidney Disease, Zhengzhou, People's Republic of China.; Key Laboratory of Precision Diagnosis and Treatment for Chronic Kidney Disease in Henan Province, Zhengzhou, People's Republic of China., Mao ZH; Traditional Chinese Medicine Integrated Department of Nephrology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, People's Republic of China.; Institute of Nephrology, Zhengzhou University, Zhengzhou, People's Republic of China.; Henan Province Research Center for Kidney Disease, Zhengzhou, People's Republic of China.; Key Laboratory of Precision Diagnosis and Treatment for Chronic Kidney Disease in Henan Province, Zhengzhou, People's Republic of China., Fu WJ; Traditional Chinese Medicine Integrated Department of Nephrology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, People's Republic of China.; Institute of Nephrology, Zhengzhou University, Zhengzhou, People's Republic of China.; Henan Province Research Center for Kidney Disease, Zhengzhou, People's Republic of China.; Key Laboratory of Precision Diagnosis and Treatment for Chronic Kidney Disease in Henan Province, Zhengzhou, People's Republic of China., Yang YY; Traditional Chinese Medicine Integrated Department of Nephrology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, People's Republic of China.; Institute of Nephrology, Zhengzhou University, Zhengzhou, People's Republic of China.; Henan Province Research Center for Kidney Disease, Zhengzhou, People's Republic of China.; Key Laboratory of Precision Diagnosis and Treatment for Chronic Kidney Disease in Henan Province, Zhengzhou, People's Republic of China., Pan SK; Traditional Chinese Medicine Integrated Department of Nephrology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, People's Republic of China.; Institute of Nephrology, Zhengzhou University, Zhengzhou, People's Republic of China.; Henan Province Research Center for Kidney Disease, Zhengzhou, People's Republic of China.; Key Laboratory of Precision Diagnosis and Treatment for Chronic Kidney Disease in Henan Province, Zhengzhou, People's Republic of China., Liu DW; Traditional Chinese Medicine Integrated Department of Nephrology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, People's Republic of China.; Institute of Nephrology, Zhengzhou University, Zhengzhou, People's Republic of China.; Henan Province Research Center for Kidney Disease, Zhengzhou, People's Republic of China.; Key Laboratory of Precision Diagnosis and Treatment for Chronic Kidney Disease in Henan Province, Zhengzhou, People's Republic of China., Liu ZS; Traditional Chinese Medicine Integrated Department of Nephrology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, People's Republic of China.; Institute of Nephrology, Zhengzhou University, Zhengzhou, People's Republic of China.; Henan Province Research Center for Kidney Disease, Zhengzhou, People's Republic of China.; Key Laboratory of Precision Diagnosis and Treatment for Chronic Kidney Disease in Henan Province, Zhengzhou, People's Republic of China., Gao ZX; Traditional Chinese Medicine Integrated Department of Nephrology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, People's Republic of China.; Institute of Nephrology, Zhengzhou University, Zhengzhou, People's Republic of China.; Henan Province Research Center for Kidney Disease, Zhengzhou, People's Republic of China.; Key Laboratory of Precision Diagnosis and Treatment for Chronic Kidney Disease in Henan Province, Zhengzhou, People's Republic of China.

المصدر: American journal of physiology. Renal physiology [Am J Physiol Renal Physiol] 2024 Jul 01; Vol. 327 (1), pp. F158-F170. Date of Electronic Publication: 2024 May 23.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: American Physiological Society Country of Publication: United States NLM ID: 100901990 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1522-1466 (Electronic) Linking ISSN: 15221466 NLM ISO Abbreviation: Am J Physiol Renal Physiol Subsets: MEDLINE

مواضيع طبية MeSH: Diabetes Mellitus, Experimental*/metabolism , Potassium*/metabolism , Potassium*/urine , Potassium, Dietary*/metabolism , Epithelial Sodium Channels*/metabolism, Animals ; Male ; Mice, Inbred C57BL ; Sodium-Glucose Transporter 2 Inhibitors/pharmacology ; Potassium Channels, Inwardly Rectifying/metabolism ; Potassium Channels, Inwardly Rectifying/genetics ; Mice ; Diabetic Nephropathies/metabolism ; Diabetic Nephropathies/etiology ; Diabetic Nephropathies/physiopathology ; Kidney/metabolism ; Kidney/drug effects ; Kidney/physiopathology ; Hypokalemia/metabolism ; Amiloride/pharmacology ; Renal Elimination/drug effects ; Homeostasis ; Solute Carrier Family 12, Member 3/metabolism ; Solute Carrier Family 12, Member 3/genetics ; Glucosides/pharmacology ; Streptozocin ; Benzhydryl Compounds ; Sodium-Glucose Transporter 2

المؤلفون: Abdelaziz R; Oncophysiology Group. Max Planck Institute for Multidisciplinary Sciences, City Campus, Göttingen, Germany., Tomczak AP; Oncophysiology Group. Max Planck Institute for Multidisciplinary Sciences, City Campus, Göttingen, Germany., Neef A; Neurophysics Laboratory, Göttingen Campus Institute for Dynamics of Biological Networks, Göttingen, Germany., Pardo LA; Oncophysiology Group. Max Planck Institute for Multidisciplinary Sciences, City Campus, Göttingen, Germany.

المصدر: ELife [Elife] 2024 Sep 11; Vol. 12. Date of Electronic Publication: 2024 Sep 11.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: eLife Sciences Publications, Ltd Country of Publication: England NLM ID: 101579614 Publication Model: Electronic Cited Medium: Internet ISSN: 2050-084X (Electronic) Linking ISSN: 2050084X NLM ISO Abbreviation: Elife Subsets: MEDLINE

مواضيع طبية MeSH: Ion Channel Gating*/physiology , Ether-A-Go-Go Potassium Channels*/metabolism , Ether-A-Go-Go Potassium Channels*/chemistry , Ether-A-Go-Go Potassium Channels*/genetics, Humans ; Animals ; Protein Domains ; Mutation ; ERG1 Potassium Channel/metabolism ; ERG1 Potassium Channel/genetics ; ERG1 Potassium Channel/chemistry

المؤلفون: Zhang ZX; Department of Neurobiology, School of Basic Medical Sciences, Peking University Health Science Center and Neuroscience Research Institute, Peking University, Beijing, China., Tian Y; Department of Neurobiology, School of Basic Medical Sciences, Peking University Health Science Center and Neuroscience Research Institute, Peking University, Beijing, China.; Key Laboratory for Neuroscience, Ministry of Education of China & National Health Commission of China, Beijing, 100191, China., Li S; Department of Neurobiology, School of Basic Medical Sciences, Peking University Health Science Center and Neuroscience Research Institute, Peking University, Beijing, China., Jing HB; Department of Neurobiology, School of Basic Medical Sciences, Peking University Health Science Center and Neuroscience Research Institute, Peking University, Beijing, China., Cai J; Department of Neurobiology, School of Basic Medical Sciences, Peking University Health Science Center and Neuroscience Research Institute, Peking University, Beijing, China.; Key Laboratory for Neuroscience, Ministry of Education of China & National Health Commission of China, Beijing, 100191, China., Li M; Department of Anesthesiology, Peking University Third Hospital, Beijing, 100191, China. liminanesth@bjmu.edu.cn., Xing GG; Department of Neurobiology, School of Basic Medical Sciences, Peking University Health Science Center and Neuroscience Research Institute, Peking University, Beijing, China. ggxing@bjmu.edu.cn.; Key Laboratory for Neuroscience, Ministry of Education of China & National Health Commission of China, Beijing, 100191, China. ggxing@bjmu.edu.cn.

المصدر: Cell communication and signaling : CCS [Cell Commun Signal] 2024 Aug 27; Vol. 22 (1), pp. 416. Date of Electronic Publication: 2024 Aug 27.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: BioMed Central Country of Publication: England NLM ID: 101170464 Publication Model: Electronic Cited Medium: Internet ISSN: 1478-811X (Electronic) Linking ISSN: 1478811X NLM ISO Abbreviation: Cell Commun Signal Subsets: MEDLINE

مواضيع طبية MeSH: Histone Deacetylase 2*/metabolism , Histone Deacetylase 2*/genetics , KCNQ2 Potassium Channel*/genetics , KCNQ2 Potassium Channel*/metabolism , Ganglia, Spinal*/metabolism , Ganglia, Spinal*/pathology , Bone Neoplasms*/genetics , Bone Neoplasms*/metabolism , Bone Neoplasms*/secondary , Bone Neoplasms*/pathology , Cancer Pain*/genetics , Cancer Pain*/metabolism , Cancer Pain*/pathology , ErbB Receptors*/metabolism , ErbB Receptors*/genetics, Animals ; Rats ; KCNQ3 Potassium Channel/genetics ; KCNQ3 Potassium Channel/metabolism ; Transcription, Genetic ; Methyl-CpG-Binding Protein 2/genetics ; Methyl-CpG-Binding Protein 2/metabolism ; Sin3 Histone Deacetylase and Corepressor Complex/genetics ; Signal Transduction/genetics ; Core Binding Factor Alpha 2 Subunit/genetics ; Core Binding Factor Alpha 2 Subunit/metabolism ; Humans ; Female ; Extracellular Signal-Regulated MAP Kinases/metabolism ; Repressor Proteins/genetics ; Repressor Proteins/metabolism ; Rats, Sprague-Dawley ; MAP Kinase Signaling System/genetics

المؤلفون: Davis J; Department of Biomedical and Molecular Sciences, Queen's University, Kingston, Ontario, Canada., Cornwell JD; Department of Biomedical and Molecular Sciences, Queen's University, Kingston, Ontario, Canada., Campagna N; Department of Biomedical and Molecular Sciences, Queen's University, Kingston, Ontario, Canada., Guo J; Department of Biomedical and Molecular Sciences, Queen's University, Kingston, Ontario, Canada., Li W; Department of Biomedical and Molecular Sciences, Queen's University, Kingston, Ontario, Canada., Yang T; Department of Biomedical and Molecular Sciences, Queen's University, Kingston, Ontario, Canada., Wang T; Department of Biomedical and Molecular Sciences, Queen's University, Kingston, Ontario, Canada., Zhang S; Department of Biomedical and Molecular Sciences, Queen's University, Kingston, Ontario, Canada. Electronic address: shetuan.zhang@queensu.ca.

المصدر: The Journal of biological chemistry [J Biol Chem] 2024 Aug; Vol. 300 (8), pp. 107526. Date of Electronic Publication: 2024 Jul 02.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Elsevier Inc. on behalf of American Society for Biochemistry and Molecular Biology Country of Publication: United States NLM ID: 2985121R Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1083-351X (Electronic) Linking ISSN: 00219258 NLM ISO Abbreviation: J Biol Chem Subsets: MEDLINE

مواضيع طبية MeSH: Long QT Syndrome*/metabolism , Long QT Syndrome*/genetics , Cell Membrane*/metabolism , ERG1 Potassium Channel*/metabolism , ERG1 Potassium Channel*/genetics, Humans ; HEK293 Cells ; Mutation, Missense ; Protein Stability ; Ether-A-Go-Go Potassium Channels/metabolism ; Ether-A-Go-Go Potassium Channels/genetics ; Protein Transport ; Amino Acid Substitution ; Animals

SCR Disease Name: Long Qt Syndrome 2

المؤلفون: Sastre D; Molecular Physiology Laboratory, Departament de Bioquímica i Biomedicina Molecular, Institut de Biomedicina (IBUB), Universitat de Barcelona, 08028 Barcelona, Spain; Department of Anesthesiology, Pharmacology and Therapeutics, Faculty of Medicine, University of British Columbia, Vancouver, Canada., Colomer-Molera M; Molecular Physiology Laboratory, Departament de Bioquímica i Biomedicina Molecular, Institut de Biomedicina (IBUB), Universitat de Barcelona, 08028 Barcelona, Spain., de Benito-Bueno A; Instituto de Investigaciones Biomédicas Alberto Sols CSIC-UAM, 28029 Madrid, Spain., Valenzuela C; Instituto de Investigaciones Biomédicas Alberto Sols CSIC-UAM, 28029 Madrid, Spain., Fernández-Ballester G; Instituto de Biología Molecular y Celular, Universidad Miguel Hernández, Elche, 03202 Alicante, Spain., Felipe A; Molecular Physiology Laboratory, Departament de Bioquímica i Biomedicina Molecular, Institut de Biomedicina (IBUB), Universitat de Barcelona, 08028 Barcelona, Spain. Electronic address: afelipe@ub.edu.

المصدر: Biochemical pharmacology [Biochem Pharmacol] 2024 Aug; Vol. 226, pp. 116368. Date of Electronic Publication: 2024 Jun 14.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Elsevier Science Country of Publication: England NLM ID: 0101032 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-2968 (Electronic) Linking ISSN: 00062952 NLM ISO Abbreviation: Biochem Pharmacol Subsets: MEDLINE

مواضيع طبية MeSH: Kv1.3 Potassium Channel*/antagonists & inhibitors , Kv1.3 Potassium Channel*/metabolism , Kv1.3 Potassium Channel*/genetics , Potassium Channels, Voltage-Gated*/metabolism , Potassium Channels, Voltage-Gated*/antagonists & inhibitors, Humans ; Animals ; Potassium Channel Blockers/pharmacology ; Cricetulus ; CHO Cells ; HEK293 Cells ; Ficusin ; Scorpion Venoms

المؤلفون: Qin C; Department of Biochemistry and Molecular Biology, College of Basic Medicine, Hubei University of Medicine, Shiyan, 442000, China.; College of Life Sciences, Wuhan University, Wuhan, 430072, China., Yang X; College of Life Sciences, Wuhan University, Wuhan, 430072, China., Zuo Z; College of Life Sciences, Wuhan University, Wuhan, 430072, China., Yuan P; College of Life Sciences, Wuhan University, Wuhan, 430072, China., Sun F; Department of Biochemistry and Molecular Biology, College of Basic Medicine, Hubei University of Medicine, Shiyan, 442000, China.; College of Life Sciences, Wuhan University, Wuhan, 430072, China., Luo X; Department of Biochemistry and Molecular Biology, College of Basic Medicine, Hubei University of Medicine, Shiyan, 442000, China., Ye X; Department of Biochemistry and Molecular Biology, College of Basic Medicine, Hubei University of Medicine, Shiyan, 442000, China., Cao Z; College of Life Sciences, Wuhan University, Wuhan, 430072, China.; Center for BioDrug Research, Wuhan University, Wuhan, 430072, China., Chen Z; Department of Biochemistry and Molecular Biology, College of Basic Medicine, Hubei University of Medicine, Shiyan, 442000, China. chenzy2005@hbmu.edu.cn.; College of Life Sciences, Wuhan University, Wuhan, 430072, China. chenzy2005@hbmu.edu.cn., Wu Y; College of Life Sciences, Wuhan University, Wuhan, 430072, China. ylwu@whu.edu.cn.; Center for BioDrug Research, Wuhan University, Wuhan, 430072, China. ylwu@whu.edu.cn.

المصدر: Scientific reports [Sci Rep] 2024 Jul 12; Vol. 14 (1), pp. 16092. Date of Electronic Publication: 2024 Jul 12.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN: 2045-2322 (Electronic) Linking ISSN: 20452322 NLM ISO Abbreviation: Sci Rep Subsets: MEDLINE

مواضيع طبية MeSH: Potassium Channel Blockers*/chemistry , Potassium Channel Blockers*/pharmacology , Scorpions*/chemistry , Scorpion Venoms*/chemistry , Scorpion Venoms*/pharmacology , Peptides*/chemistry , Peptides*/pharmacology, Animals ; Humans ; Kv1.3 Potassium Channel/antagonists & inhibitors ; Kv1.3 Potassium Channel/metabolism ; Kv1.3 Potassium Channel/chemistry ; Proteolysis ; Kv1.2 Potassium Channel/metabolism ; Kv1.2 Potassium Channel/antagonists & inhibitors ; Kv1.2 Potassium Channel/chemistry ; Protein Stability ; Amino Acid Sequence ; Patch-Clamp Techniques ; HEK293 Cells

المؤلفون: Chakraborty A; Department of Biomedical and Molecular Sciences, Queen's University, Kingston, ON, Canada., Paynter A; Department of Biomedical and Molecular Sciences, Queen's University, Kingston, ON, Canada., Szendrey M; Department of Biomedical and Molecular Sciences, Queen's University, Kingston, ON, Canada., Cornwell JD; Department of Biomedical and Molecular Sciences, Queen's University, Kingston, ON, Canada., Li W; Department of Biomedical and Molecular Sciences, Queen's University, Kingston, ON, Canada., Guo J; Department of Biomedical and Molecular Sciences, Queen's University, Kingston, ON, Canada., Yang T; Department of Biomedical and Molecular Sciences, Queen's University, Kingston, ON, Canada., Du Y; Department of Biomedical and Molecular Sciences, Queen's University, Kingston, ON, Canada., Wang T; Department of Biomedical and Molecular Sciences, Queen's University, Kingston, ON, Canada., Zhang S; Department of Biomedical and Molecular Sciences, Queen's University, Kingston, ON, Canada. Electronic address: shetuan.zhang@queensu.ca.

المصدر: The Journal of biological chemistry [J Biol Chem] 2024 Jul; Vol. 300 (7), pp. 107483. Date of Electronic Publication: 2024 Jun 17.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Elsevier Inc. on behalf of American Society for Biochemistry and Molecular Biology Country of Publication: United States NLM ID: 2985121R Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1083-351X (Electronic) Linking ISSN: 00219258 NLM ISO Abbreviation: J Biol Chem Subsets: MEDLINE

مواضيع طبية MeSH: Kv1.5 Potassium Channel*/metabolism , Kv1.5 Potassium Channel*/genetics , Ubiquitination* , Protein Kinase C*/metabolism , Protein Kinase C*/genetics , Tetradecanoylphorbol Acetate*/pharmacology , Proteolysis*, Humans ; HEK293 Cells ; Animals ; Phosphorylation ; Cell Membrane/metabolism ; Kv1.4 Potassium Channel/metabolism ; Kv1.4 Potassium Channel/genetics

المؤلفون: Abramochkin DV; Department of Human and Animal Physiology, Biological Faculty, Lomonosov Moscow State University, Leninskiye Gory, 1, 12, Moscow, Russia. abram340@mail.ru., Pustovit OB; Department of Human and Animal Physiology, Biological Faculty, Lomonosov Moscow State University, Leninskiye Gory, 1, 12, Moscow, Russia., Mironov NY; Chazov National Medical Research Center for Cardiology, Moscow, Russia., Filatova TS; Department of Human and Animal Physiology, Biological Faculty, Lomonosov Moscow State University, Leninskiye Gory, 1, 12, Moscow, Russia.; Chazov National Medical Research Center for Cardiology, Moscow, Russia.; Department of Physiology, Pirogov Russian National Research Medical University, Ostrovityanova str., 1, Moscow, Russia., Nesterova T; Institute of Immunology and Physiology, Ural Branch of Russian Academy of Sciences, 620049, Ekaterinburg, Russia.; Institute of Natural Sciences and Mathematics, Ural Federal University, 620075, Ekaterinburg, Russia.

المصدر: Naunyn-Schmiedeberg's archives of pharmacology [Naunyn Schmiedebergs Arch Pharmacol] 2024 Jul; Vol. 397 (7), pp. 5093-5104. Date of Electronic Publication: 2024 Jan 15.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Springer Verlag Country of Publication: Germany NLM ID: 0326264 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1432-1912 (Electronic) Linking ISSN: 00281298 NLM ISO Abbreviation: Naunyn Schmiedebergs Arch Pharmacol Subsets: MEDLINE

مواضيع طبية MeSH: Anti-Arrhythmia Agents*/pharmacology , ERG1 Potassium Channel*/antagonists & inhibitors , ERG1 Potassium Channel*/metabolism, Animals ; Cricetinae ; Humans ; CHO Cells ; Cricetulus ; Ether-A-Go-Go Potassium Channels/antagonists & inhibitors ; Ether-A-Go-Go Potassium Channels/metabolism ; Patch-Clamp Techniques ; Phenethylamines/pharmacology ; Potassium Channel Blockers/pharmacology ; Sulfonamides/pharmacology

المؤلفون: Zhong L; Dr. Neher's Biophysics Laboratory for Innovative Drug Discovery, State Key Laboratory of Quality Research in Chinese Medicine, Macau University of Science and Technology, Taipa, Macao SAR, China (L.Z., Z.Y., D.J., Y.O., H.Z., X.L., C.X., C.H., B.S., S.K.C., Z.-H.J., E.N., P.H.).; Macau University of Science and Technology Zhuhai MUST Science and Technology Research Institute. Zhuhai, Guangdong, China (L.Z., Z.Y., D.J., Y.O., H.Z., X.L., C.X., C.H., B.S., S.K.C., Z.-H.J., E.N., P.H.)., Yan Z; Dr. Neher's Biophysics Laboratory for Innovative Drug Discovery, State Key Laboratory of Quality Research in Chinese Medicine, Macau University of Science and Technology, Taipa, Macao SAR, China (L.Z., Z.Y., D.J., Y.O., H.Z., X.L., C.X., C.H., B.S., S.K.C., Z.-H.J., E.N., P.H.).; Macau University of Science and Technology Zhuhai MUST Science and Technology Research Institute. Zhuhai, Guangdong, China (L.Z., Z.Y., D.J., Y.O., H.Z., X.L., C.X., C.H., B.S., S.K.C., Z.-H.J., E.N., P.H.)., Jiang D; Dr. Neher's Biophysics Laboratory for Innovative Drug Discovery, State Key Laboratory of Quality Research in Chinese Medicine, Macau University of Science and Technology, Taipa, Macao SAR, China (L.Z., Z.Y., D.J., Y.O., H.Z., X.L., C.X., C.H., B.S., S.K.C., Z.-H.J., E.N., P.H.).; Macau University of Science and Technology Zhuhai MUST Science and Technology Research Institute. Zhuhai, Guangdong, China (L.Z., Z.Y., D.J., Y.O., H.Z., X.L., C.X., C.H., B.S., S.K.C., Z.-H.J., E.N., P.H.)., Weng KC; Department of Biomedical Engineering, Center for the Investigation of Membrane Excitability Disorders, Cardiac Bioelectricity and Arrhythmia Center, Washington University, St. Louis, MO (K.-C.W., J.R.S.)., Ouyang Y; Dr. Neher's Biophysics Laboratory for Innovative Drug Discovery, State Key Laboratory of Quality Research in Chinese Medicine, Macau University of Science and Technology, Taipa, Macao SAR, China (L.Z., Z.Y., D.J., Y.O., H.Z., X.L., C.X., C.H., B.S., S.K.C., Z.-H.J., E.N., P.H.).; Macau University of Science and Technology Zhuhai MUST Science and Technology Research Institute. Zhuhai, Guangdong, China (L.Z., Z.Y., D.J., Y.O., H.Z., X.L., C.X., C.H., B.S., S.K.C., Z.-H.J., E.N., P.H.)., Zhang H; Dr. Neher's Biophysics Laboratory for Innovative Drug Discovery, State Key Laboratory of Quality Research in Chinese Medicine, Macau University of Science and Technology, Taipa, Macao SAR, China (L.Z., Z.Y., D.J., Y.O., H.Z., X.L., C.X., C.H., B.S., S.K.C., Z.-H.J., E.N., P.H.).; Macau University of Science and Technology Zhuhai MUST Science and Technology Research Institute. Zhuhai, Guangdong, China (L.Z., Z.Y., D.J., Y.O., H.Z., X.L., C.X., C.H., B.S., S.K.C., Z.-H.J., E.N., P.H.)., Lin X; Dr. Neher's Biophysics Laboratory for Innovative Drug Discovery, State Key Laboratory of Quality Research in Chinese Medicine, Macau University of Science and Technology, Taipa, Macao SAR, China (L.Z., Z.Y., D.J., Y.O., H.Z., X.L., C.X., C.H., B.S., S.K.C., Z.-H.J., E.N., P.H.).; Macau University of Science and Technology Zhuhai MUST Science and Technology Research Institute. Zhuhai, Guangdong, China (L.Z., Z.Y., D.J., Y.O., H.Z., X.L., C.X., C.H., B.S., S.K.C., Z.-H.J., E.N., P.H.)., Xiao C; Dr. Neher's Biophysics Laboratory for Innovative Drug Discovery, State Key Laboratory of Quality Research in Chinese Medicine, Macau University of Science and Technology, Taipa, Macao SAR, China (L.Z., Z.Y., D.J., Y.O., H.Z., X.L., C.X., C.H., B.S., S.K.C., Z.-H.J., E.N., P.H.).; Macau University of Science and Technology Zhuhai MUST Science and Technology Research Institute. Zhuhai, Guangdong, China (L.Z., Z.Y., D.J., Y.O., H.Z., X.L., C.X., C.H., B.S., S.K.C., Z.-H.J., E.N., P.H.)., Yang H; Shanghai Key Laboratory of Regulatory Biology, Institute of Biomedical Sciences and School of Life Sciences, East China Normal University (H.Y.)., Yao J; State Key Laboratory of Virology, Hubei Key Laboratory of Cell Homeostasis, College of Life Sciences, TaiKang Center for Life and Medical Sciences, Frontier Science Center for Immunology and Metabolism, Wuhan University, China (J.Y.)., Kang X; Key Laboratory of Medical Electrophysiology, Ministry of Education of China, Collaborative Innovation Center for Prevention and Treatment of Cardiovascular Disease and the Institute of Cardiovascular Research, Southwest Medical University, Luzhou, China (X.K.).; Department of Neurosurgery, the Affiliated Hospital of Southwest Medical University, Luzhou, China (X.K.).; College of Life Sciences, Liaocheng University, China (X.K.)., Wang C; Dr. Neher's Biophysics Laboratory for Innovative Drug Discovery, State Key Laboratory of Quality Research in Chinese Medicine, Macau University of Science and Technology, Taipa, Macao SAR, China (L.Z., Z.Y., D.J., Y.O., H.Z., X.L., C.X., C.H., B.S., S.K.C., Z.-H.J., E.N., P.H.).; Department of Neurology, First Affiliated Hospital, Neuroscience Research Center, Key Laboratory of Biomedical Information Engineering of Ministry of Education, School of Life Science and Technology, Xi'an Jiaotong University, China (C.W.)., Huang C; Macau University of Science and Technology Zhuhai MUST Science and Technology Research Institute. Zhuhai, Guangdong, China (L.Z., Z.Y., D.J., Y.O., H.Z., X.L., C.X., C.H., B.S., S.K.C., Z.-H.J., E.N., P.H.)., Shen B; Dr. Neher's Biophysics Laboratory for Innovative Drug Discovery, State Key Laboratory of Quality Research in Chinese Medicine, Macau University of Science and Technology, Taipa, Macao SAR, China (L.Z., Z.Y., D.J., Y.O., H.Z., X.L., C.X., C.H., B.S., S.K.C., Z.-H.J., E.N., P.H.).; Macau University of Science and Technology Zhuhai MUST Science and Technology Research Institute. Zhuhai, Guangdong, China (L.Z., Z.Y., D.J., Y.O., H.Z., X.L., C.X., C.H., B.S., S.K.C., Z.-H.J., E.N., P.H.)., Chung SK; Dr. Neher's Biophysics Laboratory for Innovative Drug Discovery, State Key Laboratory of Quality Research in Chinese Medicine, Macau University of Science and Technology, Taipa, Macao SAR, China (L.Z., Z.Y., D.J., Y.O., H.Z., X.L., C.X., C.H., B.S., S.K.C., Z.-H.J., E.N., P.H.).; Macau University of Science and Technology Zhuhai MUST Science and Technology Research Institute. Zhuhai, Guangdong, China (L.Z., Z.Y., D.J., Y.O., H.Z., X.L., C.X., C.H., B.S., S.K.C., Z.-H.J., E.N., P.H.)., Jiang ZH; Dr. Neher's Biophysics Laboratory for Innovative Drug Discovery, State Key Laboratory of Quality Research in Chinese Medicine, Macau University of Science and Technology, Taipa, Macao SAR, China (L.Z., Z.Y., D.J., Y.O., H.Z., X.L., C.X., C.H., B.S., S.K.C., Z.-H.J., E.N., P.H.).; Macau University of Science and Technology Zhuhai MUST Science and Technology Research Institute. Zhuhai, Guangdong, China (L.Z., Z.Y., D.J., Y.O., H.Z., X.L., C.X., C.H., B.S., S.K.C., Z.-H.J., E.N., P.H.)., Zhu W; Cardiovascular Medicine Division and Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA (W.Z.)., Neher E; Dr. Neher's Biophysics Laboratory for Innovative Drug Discovery, State Key Laboratory of Quality Research in Chinese Medicine, Macau University of Science and Technology, Taipa, Macao SAR, China (L.Z., Z.Y., D.J., Y.O., H.Z., X.L., C.X., C.H., B.S., S.K.C., Z.-H.J., E.N., P.H.).; Macau University of Science and Technology Zhuhai MUST Science and Technology Research Institute. Zhuhai, Guangdong, China (L.Z., Z.Y., D.J., Y.O., H.Z., X.L., C.X., C.H., B.S., S.K.C., Z.-H.J., E.N., P.H.)., Silva JR; Department of Biomedical Engineering, Center for the Investigation of Membrane Excitability Disorders, Cardiac Bioelectricity and Arrhythmia Center, Washington University, St. Louis, MO (K.-C.W., J.R.S.)., Hou P; Dr. Neher's Biophysics Laboratory for Innovative Drug Discovery, State Key Laboratory of Quality Research in Chinese Medicine, Macau University of Science and Technology, Taipa, Macao SAR, China (L.Z., Z.Y., D.J., Y.O., H.Z., X.L., C.X., C.H., B.S., S.K.C., Z.-H.J., E.N., P.H.).; Macau University of Science and Technology Zhuhai MUST Science and Technology Research Institute. Zhuhai, Guangdong, China (L.Z., Z.Y., D.J., Y.O., H.Z., X.L., C.X., C.H., B.S., S.K.C., Z.-H.J., E.N., P.H.).

المصدر: Circulation research [Circ Res] 2024 Sep 13; Vol. 135 (7), pp. 722-738. Date of Electronic Publication: 2024 Aug 21.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Lippincott Williams & Wilkins Country of Publication: United States NLM ID: 0047103 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1524-4571 (Electronic) Linking ISSN: 00097330 NLM ISO Abbreviation: Circ Res Subsets: MEDLINE

مواضيع طبية MeSH: Cyclic AMP-Dependent Protein Kinases*/metabolism , KCNQ1 Potassium Channel*/genetics , KCNQ1 Potassium Channel*/metabolism , Induced Pluripotent Stem Cells*/metabolism, Humans ; Phosphorylation ; Romano-Ward Syndrome/genetics ; Romano-Ward Syndrome/metabolism ; Cyclic AMP/metabolism ; Myocytes, Cardiac/metabolism ; Mutation ; Long QT Syndrome/genetics ; Long QT Syndrome/metabolism ; HEK293 Cells ; Potassium Channels, Voltage-Gated

المؤلفون: Youn JH; Department of Physiology and Neuroscience, University of Southern California Keck School of Medicine, Los Angeles, CA 90089, USA., Gili S; Department of Geosciences, Princeton University, Princeton, NJ 08544, USA., Oh Y; Department of Physiology and Neuroscience, University of Southern California Keck School of Medicine, Los Angeles, CA 90089, USA., McDonough AA; Department of Physiology and Neuroscience, University of Southern California Keck School of Medicine, Los Angeles, CA 90089, USA., Higgins J; Department of Geosciences, Princeton University, Princeton, NJ 08544, USA.

المصدر: International journal of molecular sciences [Int J Mol Sci] 2024 Sep 06; Vol. 25 (17). Date of Electronic Publication: 2024 Sep 06.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067 (Electronic) Linking ISSN: 14220067 NLM ISO Abbreviation: Int J Mol Sci Subsets: MEDLINE

مواضيع طبية MeSH: Potassium*/metabolism, Animals ; Rats ; Kinetics ; Male ; Potassium, Dietary/metabolism ; Models, Biological ; Muscle, Skeletal/metabolism