المؤلفون: Mudry, J. M., Alm, P. S., Erhardt, S., Goiny, M., Fritz, T., Caidahl, Kenneth, 1949, Zierath, J. R., Krook, A., Wallberg-Henriksson, H.

المساهمون: Göteborgs universitet, Sahlgrenska akademin, Institutionen för medicin, avdelningen för molekylär och klinisk medicin, Gothenburg University, Sahlgrenska Academy, Institute of Medicine, Department of Molecular and Clinical Medicine

المصدر: Diabetes/Metabolism Research Reviews. 32(7):754-761

مصطلحات موضوعية: Endokrinologi och diabetes, Endocrinology and Diabetes, Biomarkers/*metabolism, Blood Glucose/metabolism, Case-Control Studies, Diabetes Mellitus, Type 2/*physiopathology, Exercise/*physiology, Female, Follow-Up Studies, Glucose Tolerance Test, Glycated Hemoglobin A/metabolism, Humans, Kynurenine/*metabolism, Male, Middle Aged, Muscle, Skeletal/*metabolism, PPAR alpha/metabolism, Prognosis, Transaminases/metabolism, *exercise, *skeletal muscle, *type 2 diabetes

URL الوصول: https://gup.ub.gu.se/publication/268008

المؤلفون: Norrbom, Jessica

مصطلحات موضوعية: Exercise -- physiology, Muscle, skeletal -- metabolism, Mitochondria, muscle -- metabolism, Transcription factors -- metabolism, PPAR alpha -- metabolism, PPAR delta -- metabolism, Skelettmuskler, Fysisk träning

Degree: Diss. (sammanfattning) Stockholm : Karolinska institutet, 2008

المؤلفون: Fruchart, J.C., Santos, R.D., Aguilar-Salinas, C., Aikawa, M., Al Rasadi, K., Amarenco, P., Barter, P.J., Ceska, R., Corsini, A., Després, J.P., Duriez, P., Eckel, R.H., Ezhov, M.V., Farnier, M., Ginsberg, H.N., Hermans, M.P., Ishibashi, S., Karpe, F., Kodama, T., Koenig, W., Krempf, M., Lim, S., Lorenzatti, A.J., McPherson, R., Nuñez-Cortes, J.M., Nordestgaard, B.G., Ogawa, H., Packard, C.J., Plutzky, J., Ponte-Negretti, C.I., Pradhan, A., Ray, K.K., Reiner, Ž., Ridker, P.M., Ruscica, M., Sadikot, S., Shimano, H., Sritara, P., Stock, J.K., Su, T.C., Susekov, A.V., Tartar, A., Taskinen, M.R., Tenenbaum, A., Tokgözoğlu, L.S., Tomlinson, B., Tybjærg-Hansen, A., Valensi, P., Vrablík, M., Wahli, W., Watts, G.F., Yamashita, S., Yokote, K., Zambon, A., Libby, P.

المصدر: Cardiovascular diabetology, vol. 18, no. 1, pp. 71

مصطلحات موضوعية: Animals, Benzoxazoles/adverse effects, Benzoxazoles/therapeutic use, Biomarkers/blood, Butyrates/adverse effects, Butyrates/therapeutic use, Cardiovascular Diseases/blood, Cardiovascular Diseases/diagnosis, Cardiovascular Diseases/prevention & control, Consensus, Dyslipidemias/blood, Dyslipidemias/diagnosis, Dyslipidemias/drug therapy, Humans, Hypolipidemic Agents/adverse effects, Hypolipidemic Agents/therapeutic use, Lipids/blood, Molecular Targeted Therapy, PPAR alpha/agonists, PPAR alpha/metabolism, Patient Safety, Risk Assessment, Risk Factors, Signal Transduction, Treatment Outcome, Atherogenic dyslipidemia, Diabetes, Inflammation, PROMINENT, Pemafibrate (K-877), Remnant cholesterol, Residual cardiovascular risk, SPPARMalpha, Selective peroxisome proliferator-activated receptor alpha modulator, Triglycerides, Visceral obesity

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=od______1900::1e42e4b07a96300e14b1450540aec81b
https://serval.unil.ch/resource/serval:BIB_A62033B5071E.P001/REF.pdf

المؤلفون: Michaël Baruchet, Aurélien Naldi, Cristina Casals-Casas, Béatrice Desvergne, Sylvain Pradervand, Leonore Wigger, Khanh B. Trang

المصدر: PLoS ONE
PloS one, vol. 14, no. 8, pp. e0220894
PLoS ONE, Vol 14, Iss 8, p e0220894 (2019)

مصطلحات موضوعية: 0301 basic medicine, Benzylamines, Systems Analysis, Cellular differentiation, Gene Expression, Receptors, Cytoplasmic and Nuclear, Cell Cycle Proteins, Biochemistry, Benzoates, 0302 clinical medicine, Cell Signaling, Animal Cells, Medicine and Health Sciences, Cell Cycle and Cell Division, Promoter Regions, Genetic, Receptor, Liver X Receptors, Regulation of gene expression, Hepatocyte differentiation, 0303 health sciences, Multidisciplinary, Chemistry, Cell Cycle, Cell Differentiation, Cell cycle, Orphan Nuclear Receptors, Cell biology, Butyrates, medicine.anatomical_structure, Liver, Cellular Crosstalk, Cell Processes, 030220 oncology & carcinogenesis, Hepatocyte, Medicine, Metabolic Pathways, Cellular Types, Anatomy, Research Article, Signal Transduction, Agonist, medicine.drug_class, Science, Cell Cycle/genetics, Cell Cycle/physiology, Cell Cycle Proteins/physiology, Cell Differentiation/physiology, Cell Line, Cell Proliferation/physiology, Gene Expression/genetics, Gene Expression Regulation/genetics, Hepatocytes/metabolism, Humans, Isoxazoles, Liver/pathology, Liver X Receptors/immunology, Liver X Receptors/metabolism, Orphan Nuclear Receptors/metabolism, PPAR alpha/immunology, PPAR alpha/metabolism, Phenylurea Compounds, Promoter Regions, Genetic/genetics, Receptor Cross-Talk/physiology, Receptors, Cytoplasmic and Nuclear/immunology, Receptors, Cytoplasmic and Nuclear/metabolism, Context (language use), Polyploidy, 03 medical and health sciences, Genetics, medicine, Gene Regulation, PPAR alpha, Liver X receptor, Cell Proliferation, 030304 developmental biology, Biology and Life Sciences, Cell Biology, Receptor Cross-Talk, Tetraploidy, Metabolism, 030104 developmental biology, Gene Expression Regulation, Nuclear receptor, Hepatocytes, Departures from Diploidy, Developmental Biology

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c60a36afdcfd2a4dea2013c578bd6a5e
https://doi.org/10.1101/514976

المؤلفون: Anne-Françoise Burnol, Arnaud Polizzi, Marcio Do-Cruzeiro, Hervé Guillou, Emilie Tournier, Alison Iroz, Céline Lukowicz, Walter Wahli, Edwin Fouché, Solenne Marmier, Jean Girard, Renaud Dentin, Catherine Postic, Elodie Anthony, Fadila Benhamed, Françoise Levavasseur, Marion Régnier, Martine Daujat-Chavanieu, Yannick Lippi, Sandra Guilmeau, Véronique Fauveau, Sabine Gerbal-Chalouin, Michele Cauzac, Alexandra Montagner

المساهمون: Institut Cochin (IC UM3 (UMR 8104 / U1016)), Université Paris Descartes - Paris 5 (UPD5)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), Université Fédérale Toulouse Midi-Pyrénées, ToxAlim (ToxAlim), Université Toulouse III - Paul Sabatier (UT3), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-Institut National Polytechnique (Toulouse) (Toulouse INP), Université Fédérale Toulouse Midi-Pyrénées-Ecole Nationale Vétérinaire de Toulouse (ENVT), Institut National Polytechnique (Toulouse) (Toulouse INP), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-Ecole d'Ingénieurs de Purpan (INPT - EI Purpan), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-Institut National de la Recherche Agronomique (INRA), Cellules Souches, Plasticité Cellulaire, Médecine Régénératrice et Immunothérapies (IRMB), Centre Hospitalier Régional Universitaire [Montpellier] (CHRU Montpellier)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Montpellier (UM), Institut Cochin (UMR_S567 / UMR 8104), Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Université Paris Descartes - Paris 5 (UPD5), Dentin, Renaud, Guillou, Hervé, Postic, Catherine, Toxicologie Intégrative & Métabolisme (ToxAlim-TIM), Institut National de la Recherche Agronomique (INRA)-Université Toulouse III - Paul Sabatier (UT3), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-Ecole Nationale Vétérinaire de Toulouse (ENVT), Université Fédérale Toulouse Midi-Pyrénées-Ecole d'Ingénieurs de Purpan (INPT - EI Purpan), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-Institut National de la Recherche Agronomique (INRA)-Université Toulouse III - Paul Sabatier (UT3), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées, Prévention et promotion de la cancérogénèse par les aliments (ToxAlim-PPCA), Université de Montpellier (UM)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre Hospitalier Régional Universitaire [Montpellier] (CHRU Montpellier), Transcriptomic impact of Xenobiotics (E23 TRiX), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-Plateforme Génome & Transcriptome (GET), Génopole Toulouse Midi-Pyrénées [Auzeville] (GENOTOUL), Université Fédérale Toulouse Midi-Pyrénées-Institut National de la Santé et de la Recherche Médicale (INSERM)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE)-Université Toulouse III - Paul Sabatier (UT3), Université Fédérale Toulouse Midi-Pyrénées-Institut National de la Santé et de la Recherche Médicale (INSERM)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE)-Génopole Toulouse Midi-Pyrénées [Auzeville] (GENOTOUL), Université Fédérale Toulouse Midi-Pyrénées-Institut National de la Santé et de la Recherche Médicale (INSERM)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE), H. Guillou's lab (TIM, ToxAlim) is supported by grants from Region Occitanie. W.W. was supported by a start-up grant from Lee Kong Chian School of Medicine, Nanyang Technological University. C. Postic's lab (U1016-Institut Cochin) is supported by grants from ChroME Network (Marie Curie Sklodowska Action H2020-MSCA-ITN-2015-675610), the Foundation for the Medical Research (FRM) (DEQ20150331744), and the European Foundation for the Study of Diabetes (EFSD) Novonordisk. H. Guillou's and C. Postic's labs are also supported by grants from the National Agency for Research (ANR) (ANR- 12BSV1-0025-ObeLiP and ANR -15-CE14-0026-Hepatokind). R. Dentin's lab (U1016-Institut Cochin) is supported by the European Research Council (ERC-2013-StG-336629) and the city of Paris (Projet Emergences-2011), Lee Kong Chian School of Medicine (LKCMedicine), Centre National de la Recherche Scientifique (CNRS)-Université Paris Descartes - Paris 5 (UPD5)-Institut National de la Santé et de la Recherche Médicale (INSERM), Institut National des Sciences Appliquées - Toulouse (INSA Toulouse), Institut National des Sciences Appliquées (INSA)-Institut National des Sciences Appliquées (INSA)-Université Toulouse III - Paul Sabatier (UT3), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE)-Ecole Nationale Vétérinaire de Toulouse (ENVT), Université Fédérale Toulouse Midi-Pyrénées-Institut National de la Santé et de la Recherche Médicale (INSERM)-Institut National des Sciences Appliquées - Toulouse (INSA Toulouse), Université Fédérale Toulouse Midi-Pyrénées-Institut National de la Santé et de la Recherche Médicale (INSERM)-Génopole Toulouse Midi-Pyrénées [Auzeville] (GENOTOUL), Institut National des Sciences Appliquées (INSA)-Institut National des Sciences Appliquées (INSA)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE)-Institut National de la Santé et de la Recherche Médicale (INSERM), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-Institut National de la Recherche Agronomique (INRA)-Plateforme Génome & Transcriptome (GET)

المصدر: Cell Reports
Cell Reports, Elsevier Inc, 2017, 21 (2), pp.403-416. ⟨10.1016/j.celrep.2017.09.065⟩
Cell Reports 2 (21), 403-416. (2017)
Cell Reports, Vol 21, Iss 2, Pp 403-416 (2017)
Cell reports, vol. 21, no. 2, pp. 403-416

مصطلحات موضوعية: Male, 0301 basic medicine, medicine.medical_specialty, FGF21, ChREBP, [SDV]Life Sciences [q-bio], sucrose preference, toxicologie alimentaire, 030209 endocrinology & metabolism, Context (language use), Biology, Carbohydrate metabolism, Response Elements, Toxicology, PPARα, Toxicology and food chain, Article, General Biochemistry, Genetics and Molecular Biology, Mice, 03 medical and health sciences, 0302 clinical medicine, Internal medicine, Animals, Cells, Cultured, Female, Fibroblast Growth Factors/genetics, Fibroblast Growth Factors/metabolism, Glucose/metabolism, Hepatocytes/metabolism, Mice, Inbred C57BL, Nuclear Proteins/genetics, Nuclear Proteins/metabolism, PPAR alpha/genetics, PPAR alpha/metabolism, Transcription Factors/genetics, Transcription Factors/metabolism, glucose intake, medicine, PPAR alpha, Receptor, Carbohydrate-responsive element-binding protein, Transcription factor, lcsh:QH301-705.5, Toxicologie, Toxicologie et chaîne alimentaire, ComputingMilieux_MISCELLANEOUS, Basic Helix-Loop-Helix Leucine Zipper Transcription Factors, Nuclear Proteins, Fibroblast Growth Factors, Glucose, 030104 developmental biology, Endocrinology, Nuclear receptor, lcsh:Biology (General), Knockout mouse, Hepatocytes, Transcription Factors

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d2440405e9afebdd2072ecbfc3a0088
https://hal.umontpellier.fr/hal-01837159

المؤلفون: Joffrey Zoll, Jean-François Decaux, Mathias Mericskay, Marie Breton, Anne Garnier, Boris Manoury, Mélanie Gressette, Cynthia Tannous, Jérôme Piquereau, Charles Brenner, Nicolas Diguet, István Baczkó, Samuel A.J. Trammell, Jocelyne Blanc, Zhenlin Li, Anne Gouge, Nathalie Mougenot, Gareth G. Lavery, Robin Deloux

المساهمون: Adaptation Biologique et Vieillissement = Biological Adaptation and Ageing (B2A), Institut National de la Santé et de la Recherche Médicale (INSERM)-Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS)-Institut de Biologie Paris Seine (IBPS), Institut National de la Santé et de la Recherche Médicale (INSERM)-Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS), Signalisation et physiopathologie cardiovasculaire (UMRS1180), Institut National de la Santé et de la Recherche Médicale (INSERM), Phénotypage du petit animal (UMS28), Université Pierre et Marie Curie - Paris 6 (UPMC), Détoxication et réparation tissulaire, Université de Rennes (UR)-Institut National de la Santé et de la Recherche Médicale (INSERM), Laboratoire de Photophysique et Photochimie Supramoléculaires et Macromoléculaires (PPSM), École normale supérieure - Cachan (ENS Cachan)-Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS), Centre de Recherche Cardiovasculaire de Lariboisiere, Université Paris Diderot - Paris 7 (UPD7)-Institut National de la Santé et de la Recherche Médicale (INSERM), This study was supported by the Association Française contre les Myopathies (AFM N 16282), the Agence Nationale de la Recherche (ANR) grant NAD-Heart ANR-17-CE17-0015-01 and ANR-08-GENOPAT-038, Fondation de France grant 00075811 and fundings from Institut National pour la Santé Et la Recherche Médicale (INSERM), Center National de la Recherche Scientifique (CNRS), Université Pierre et Marie Curie Paris 6, and University Paris Sud. Drs Diguet and Tannous, and Mr Deloux were supported by a PhD fellowship of French Ministère de la Recherche et de l’Enseignement Supérieur. Dr Diguet was further supported by a 1-year PhD fellowship from AFM. Dr Brenner is supported by the Roy J. Carver Trust. GGL is supported by a Wellcome Trust Senior Fellowship (104612/Z/14/Z)., The authors thank V. Veksler and R. Ventura-Clapier (Inserm UMR-S 1180) for expert advice on respiration assays, Luc Bertrand (UCL, Belgium) for expert advice on AMPK detection, A. Angelini (UMR 8256) for technical help in these assays, A. Grosfeld (UMR 8256) for preliminary setup experiments for Nmrk2 cloning, Florence Lefebvre for adult rat cardiomyocyte isolation., ANR-17-CE17-0015,NAD-HEART,Supplémentation en précurseur du NAD+ pour le traitement de l'insuffisance cardiaque(2017), ANR-08-GENO-0038,REMODEL-SRF,Remodelage des organes creux musculaires et dilatations: établir un lien avec le Facteur de Réponse au Sérum(2008), Institut National de la Santé et de la Recherche Médicale (INSERM)-Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), Université de Rennes 1 (UR1), Université de Rennes (UNIV-RENNES)-Université de Rennes (UNIV-RENNES)-Institut National de la Santé et de la Recherche Médicale (INSERM), SIGNALISATION ET PHYSIOPATHOLOGIE CARDIOVASCULAIRE (UMRS1180, LabEx LERMIT), Université de Rennes (UNIV-RENNES)-Université de Rennes (UNIV-RENNES)-IFR140-Institut National de la Santé et de la Recherche Médicale (INSERM), École normale supérieure - Cachan (ENS Cachan)-Centre National de la Recherche Scientifique (CNRS), ANR-17-CE17-0015,NAD-HEART,Supplémentation en précurseur du NAD+ pour le traitement de l’insuffisance cardiaque(2017), DECAUX, Jean-François, Supplémentation en précurseur du NAD+ pour le traitement de l'insuffisance cardiaque - - NAD-HEART2017 - ANR-17-CE17-0015 - AAPG2017 - VALID, Du gène à la physiopathologie, des maladies rares aux maladies communes - Remodelage des organes creux musculaires et dilatations: établir un lien avec le Facteur de Réponse au Sérum - - REMODEL-SRF2008 - ANR-08-GENO-0038 - GENOPAT - VALID

المصدر: Circulation
Circulation, 2018, 137 (21), pp.2256-2273. ⟨10.1161/CIRCULATIONAHA.116.026099⟩
Circulation, American Heart Association, 2018, 137 (21), pp.2256-2273. ⟨10.1161/CIRCULATIONAHA.116.026099⟩

مصطلحات موضوعية: 0301 basic medicine, MESH: Niacinamide/analogs & derivatives, Serum Response Factor, MESH: Cytokines/genetics, Cardiomyopathy, MESH: Dietary Supplements, Pyridinium Compounds, Pharmacology, MESH: Acrylamides/therapeutic use, MESH: Myocytes, Cardiac/cytology, AMP-Activated Protein Kinases, [SDV.BBM.BM] Life Sciences [q-bio]/Biochemistry, Molecular Biology/Molecular biology, nicotinamide-beta-riboside, MESH: Cardiomyopathy, Dilated/drug therapy, chemistry.chemical_compound, Mice, Piperidines, energy metabolism, Glycolysis, MESH: Animals, MESH: PPAR alpha/metabolism, Myocytes, Cardiac, MESH: Piperidines/therapeutic use, Nicotinamide Phosphoribosyltransferase, Dilated cardiomyopathy, glycolysis, MESH: Myocytes, Cardiac/metabolism, MESH: Phosphotransferases (Alcohol Group Acceptor)/metabolism, Phosphotransferases (Alcohol Group Acceptor), MESH: Heart Failure/prevention & control, Metabolome, Cytokines, MESH: NAD/metabolism, Cardiology and Cardiovascular Medicine, dilated, acetyl coenzyme A, Cardiac function curve, Cardiomyopathy, Dilated, Niacinamide, MESH: Rats, MESH: Mice, Transgenic, Mice, Transgenic, Oxidative phosphorylation, MESH: Serum Response Factor/genetics, Citric Acid, MESH: Metabolome/drug effects, MESH: Nicotinamide Phosphoribosyltransferase/metabolism, 03 medical and health sciences, MESH: Gene Expression Profiling, MESH: Citric Acid/metabolism, Physiology (medical), medicine, [SDV.BBM] Life Sciences [q-bio]/Biochemistry, Molecular Biology, MESH: Niacinamide/therapeutic use, Animals, MESH: Serum Response Factor/deficiency, [SDV.BBM]Life Sciences [q-bio]/Biochemistry, Molecular Biology, PPAR alpha, MESH: Myocytes, Cardiac/drug effects, MESH: Mice, Heart Failure, Acrylamides, business.industry, MESH: Phosphotransferases (Alcohol Group Acceptor)/genetics, Gene Expression Profiling, [SDV.BBM.BM]Life Sciences [q-bio]/Biochemistry, Molecular Biology/Molecular biology, MESH: Nicotinamide Phosphoribosyltransferase/genetics, medicine.disease, NAD, Rats, MESH: AMP-Activated Protein Kinases/metabolism, Disease Models, Animal, 030104 developmental biology, chemistry, Heart failure, Nicotinamide riboside, Dietary Supplements, NAD+ kinase, MESH: Cytokines/metabolism, MESH: Disease Models, Animal, business, cardiomyopathy, MESH: Phosphotransferases (Alcohol Group Acceptor)/antagonists & inhibitors

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ff8c9d79a5527d8a72b3544c248b40d
https://pubmed.ncbi.nlm.nih.gov/29784693

المؤلفون: Arnaud Polizzi, Alexandra Montagner, A. Marmugi, Walter Wahli, Laila Mselli-Lakhal, Frédéric Lasserre, Edwin Fouché, Nicolas Loiseau, Simon Ducheix, Hervé Guillou

المساهمون: ToxAlim (ToxAlim), Université Toulouse III - Paul Sabatier (UT3), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-Institut National Polytechnique (Toulouse) (Toulouse INP), Université Fédérale Toulouse Midi-Pyrénées-Ecole Nationale Vétérinaire de Toulouse (ENVT), Institut National Polytechnique (Toulouse) (Toulouse INP), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-Ecole d'Ingénieurs de Purpan (INPT - EI Purpan), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-Institut National de la Recherche Agronomique (INRA), Lee Kong Chian School of Medicine, Nanyang Technological University [Singapour], Center for Integrative Genomics, Université de Lausanne, This work was funded by the Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore Start-Up Grant (to Walter Wahli), by ANRs 'Hepatokind' (to Herve Guillou). Alexandra Montagner, Walter Wahli, and Herve Guillou were supported by Région Midi-Pyrénées, Lee Kong Chian School of Medicine (LKCMedicine), Guillou, Hervé, Montagner, Alexandra, Toxicologie Intégrative & Métabolisme (ToxAlim-TIM), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-Institut National de la Recherche Agronomique (INRA)-Université Toulouse III - Paul Sabatier (UT3), Prévention et promotion de la cancérogénèse par les aliments (ToxAlim-PPCA), Exposition, Perturbation Endocrino-métabolique et Reproduction (ToxAlim-EXPER), Nanyang Technological University (NTU), Center for Integrative Genomics - Institute of Bioinformatics, Génopode (CIG), Swiss Institute of Bioinformatics [Lausanne] (SIB), Université de Lausanne (UNIL)-Université de Lausanne (UNIL)

المصدر: International Journal of Molecular Sciences
International Journal of Molecular Sciences, MDPI, 2016, 17 (10), pp.1624. ⟨10.3390/ijms17101624⟩
International Journal of Molecular Sciences, Vol 17, Iss 10, p 1624 (2016)
International Journal of Molecular Sciences 10 (17), 1624. (2016)
International Journal of Molecular Sciences; Volume 17; Issue 10; Pages: 1624
International journal of molecular sciences, vol. 17, no. 10, pp. 1624

مصطلحات موضوعية: Male, 0301 basic medicine, récepteur ppar, liver diseases, Peroxisome proliferator-activated receptor, nuclear receptors, human health, PPARα, lcsh:Chemistry, Mice, chemistry.chemical_compound, 0302 clinical medicine, pparalpha, Cytochrome P-450 Enzyme System, steatosis, nuclear receptor, Receptor, lcsh:QH301-705.5, Spectroscopy, récepteur nucléaire, Mice, Knockout, chemistry.chemical_classification, biology, acide gras, dietary fatty acids, Alanine Transaminase, General Medicine, santé humaine, polyunsaturated fatty acid, Computer Science Applications, Cholesterol, Liver, fasting, polyunsaturated fatty acids, PPAR alpha, 030211 gastroenterology & hepatology, Polyunsaturated fatty acid, medicine.medical_specialty, Médecine humaine et pathologie, Article, Catalysis, Inorganic Chemistry, 03 medical and health sciences, acide gras polyinsaturé, Internal medicine, medicine, Animals, Aspartate Aminotransferases, Cytochrome P450 Family 4, RNA, Messenger, Alanine Transaminase/blood, Aspartate Aminotransferases/blood, Body Weight, Cholesterol/blood, Cytochrome P-450 Enzyme System/genetics, Cytochrome P450 Family 4/genetics, Dietary Fats, Fasting, Fatty Liver/metabolism, Fatty Liver/pathology, Fibroblast Growth Factors/genetics, Liver/metabolism, Liver/pathology, Mice, Inbred C57BL, PPAR alpha/genetics, PPAR alpha/metabolism, RNA, Messenger/metabolism, Triglycerides/blood, Physical and Theoretical Chemistry, adipocyte protein 2, Molecular Biology, Triglycerides, stéatose, Fatty acid metabolism, Organic Chemistry, Fatty acid, medicine.disease, Fatty Liver, Fibroblast Growth Factors, 030104 developmental biology, Endocrinology, lcsh:Biology (General), lcsh:QD1-999, chemistry, biology.protein, Human health and pathology, fatty acid, Steatosis, maladie du foie, [SDV.MHEP]Life Sciences [q-bio]/Human health and pathology, Hormone

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::46ff3ba0a74b71736831bec77fdcefa3
https://hal.archives-ouvertes.fr/hal-01476503

المؤلفون: Améen, Caroline, 1975, Edvardsson, Ulrika, 1967, Ljungberg, Anna, 1977, Asp, Lennart, 1965, Akerblad, P., Tuneld, A., Olofsson, Sven-Olof, 1947, Lindén, Daniel, 1971, Oscarsson, Jan, 1960

المصدر: J Biol Chem. 280(2):1224-9

مصطلحات موضوعية: MEDICAL AND HEALTH SCIENCES, MEDICIN OCH HÄLSOVETENSKAP, Animals, Apolipoproteins B/metabolism/secretion, Carrier Proteins/*genetics/*metabolism, Cell Line, Cells, Cultured, Dactinomycin/pharmacology, *Gene Expression Regulation/drug effects, Hepatocytes/drug effects/metabolism, Liver/cytology/drug effects/*metabolism, Male, Mice, Inbred C57BL, PPAR alpha/*metabolism, Promoter Regions (Genetics)/genetics, Pyrimidines/pharmacology, RNA, Messenger/genetics/metabolism, Rats, Sprague-Dawley, Thiazolidinediones/pharmacology, Transcription, Genetic/drug effects, Tretinoin/pharmacology

URL الوصول: https://gup.ub.gu.se/publication/50670

المؤلفون: Pierre Chambon, Daniel Meztger, Jan Kopecky, M Hensler, Pavel Flachs, Zuzana Macek Jilkova, Walter Wahli, Kristina Bardova

المصدر: Lipids in Health and Disease, Vol 10, Iss 1, p 128 (2011)
Lipids in Health and Disease
Lipids in Health and Disease, vol. 10, no. 1, pp. 128
Lipids in health and disease

مصطلحات موضوعية: Male, DHA and EPA, Endocrinology, Diabetes and Metabolism, Clinical Biochemistry, Drug Evaluation, Preclinical, Adipose tissue, Fat cell proliferation, Gene Expression, fish oil, chemistry.chemical_compound, Gene Knockout Techniques, Mice, 0302 clinical medicine, Endocrinology, Weight loss, Adipocyte, Adipocytes, lcsh:RC620-627, chemistry.chemical_classification, Epididymis, 0303 health sciences, Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha, lcsh:Nutritional diseases. Deficiency diseases, medicine.symptom, Stearoyl-CoA Desaturase, Polyunsaturated fatty acid, Lipidology, medicine.medical_specialty, Peroxisome proliferator-activated receptor gamma, fat cell turnover, Short Report, 030209 endocrinology & metabolism, Mice, Transgenic, Biology, 03 medical and health sciences, Internal medicine, Fatty Acids, Omega-3, medicine, Animals, PPAR alpha, Obesity, 030304 developmental biology, Cell Proliferation, Biochemistry, medical, Biochemistry (medical), Proteins, PPAR gamma, chemistry, Prostaglandin-Endoperoxide Synthases, Trans-Activators, Corn Oil, Adipocytes/drug effects, Adipocytes/pathology, Cell Proliferation/drug effects, Corn Oil/adverse effects, Epididymis/metabolism, Epididymis/pathology, Fatty Acids, Omega-3/pharmacology, Obesity/chemically induced, Obesity/prevention & control, PPAR alpha/genetics, PPAR alpha/metabolism, PPAR gamma/genetics, Prostaglandin-Endoperoxide Synthases/genetics, Prostaglandin-Endoperoxide Synthases/metabolism, Proteins/genetics, Proteins/metabolism, Stearoyl-CoA Desaturase/genetics, Stearoyl-CoA Desaturase/metabolism, Trans-Activators/genetics, Trans-Activators/metabolism, Corn oil, Transcription Factors

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::88659930651a934b433ec2291a4638e8
http://www.lipidworld.com/content/10/1/128

المؤلفون: Cristina Casals-Casas, Elodie Bedu, Jerome N. Feige, Qian Yang, Laurent Gelman, Alan Gerber, Manuel Bueno, Carine Winkler, Frank J. Gonzalez, Johan Auwerx, Béatrice Desvergne

المساهمون: Organic Chemistry, AIMMS

المصدر: Environmental Health Perspectives, 118(2), 234-241. Public Health Services, US Dept of Health and Human Services
Feige, J N, Gerber, A, Casals-Casas, C, Yang, Q, Winkler, C, Bedu, E, Bueno, M, Gelman, L, Auwerx, J, Gonzalez, F J & Desvergne, B 2010, ' The pollutant diethylhexyl phthalate regulates hepatic energy metabolism via species-specific PPARα-dependent mechanisms ', Environmental Health Perspectives, vol. 118, no. 2, pp. 234-241 . https://doi.org/10.1289/ehp.0901217
Environmental Health Perspectives
Environmental Health Perspectives, vol. 118, no. 2, pp. 234-241

مصطلحات موضوعية: endocrine system, Health, Toxicology and Mutagenesis, Science Selections, Animals, Cell Line, Diethylhexyl Phthalate/pharmacology, Energy Metabolism/drug effects, Fatty Acids/metabolism, Glucose Tolerance Test, Liver/drug effects, Liver/metabolism, Mice, Mice, Inbred C57BL, Mice, Transgenic, Obesity/chemically induced, Obesity/prevention & control, Oxidation-Reduction/drug effects, PPAR alpha/metabolism, Phenotype, Plasticizers/pharmacology, Peroxisome proliferator-activated receptor, Peroxisome Proliferation, Biology, News, PPAR, chemistry.chemical_compound, SDG 3 - Good Health and Well-being, Plasticizers, Diethylhexyl Phthalate, PPAR alpha, Obesity, Receptor, Species specificity, chemistry.chemical_classification, DEHP, Catabolism, Research, Fatty Acids, Public Health, Environmental and Occupational Health, Phthalate, Peroxisome, Metabolism, Endocrine disruptor, chemistry, Biochemistry, Liver, Energy Metabolism, Oxidation-Reduction, Homeostasis

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::83e2a6beafc914c235152ec24aa16cd8
https://research.vu.nl/en/publications/0e8f9eea-6576-469a-83a1-707e86d5cba7