المؤلفون: Victoria Jackson-Patel, Emily Liu, Matthew R. Bull, Amir Ashoorzadeh, Gib Bogle, Anna Wolfram, Kevin O. Hicks, Jeff B. Smaill, Adam V. Patterson

المصدر: Frontiers in Pharmacology, Vol 13 (2022)

مصطلحات موضوعية: CP-506, SN36506, PR-104 (PubChem CID: 11455973), PR-104A (PubChem CID: 9848786), bystander effect, hypoxia-activated prodrug, Therapeutics. Pharmacology, RM1-950

وصف الملف: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fphar.2022.803602/full; https://doaj.org/toc/1663-9812

URL الوصول: https://doaj.org/article/c34ba5238adc4eb49a0ab52ce8b13172

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المؤلفون: David F. Ackerley, Janine N. Copp, Laura K. Green, Mathew A. Storey, Elsie M. Williams, Jeff B. Smaill, Adam V. Patterson

المصدر: Cancers, Vol 5, Iss 3, Pp 985-997 (2013)

مصطلحات موضوعية: gene therapy, GDEPT, nitroaromatic prodrug, nitroreductase, CB1954, PR-104A, Nitro-CBI-DEI, SOS chromotest, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

وصف الملف: electronic resource

Relation: http://www.mdpi.com/2072-6694/5/3/985; https://doaj.org/toc/2072-6694

URL الوصول: https://doaj.org/article/75ac209361c14329b19973e5b1f7084c

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المؤلفون: R. Biemans, Maria R. Abbattista, Philippe Lambin, Ludwig Dubois, Sophie P. Syddall, Jan Theys, Alexandra M. Mowday, N. Lieuwes, Christopher P. Guise, Janine N. Copp, Amir Ashoorzadeh, Elsie M. Williams, David F. Ackerley, Jingli Wang, Jeff B. Smaill, Adam V. Patterson

المساهمون: RS: GROW - R2 - Basic and Translational Cancer Biology, Precision Medicine, RS: GROW - R3 - Innovative Cancer Diagnostics & Therapy

المصدر: Theranostics
Theranostics, 10(23), 10548-10562. Ivyspring International Publisher

مصطلحات موضوعية: EXPRESSION, BIOMARKER, 0301 basic medicine, ANTITUMOR-ACTIVITY, Genetic enhancement, PET imaging, Medicine (miscellaneous), Context (language use), nitroreductase, TUMOR HYPOXIA, 03 medical and health sciences, Nitroreductase, POSITRON-EMISSION-TOMOGRAPHY, 0302 clinical medicine, In vivo, Gene expression, ABLATION, OXIDOREDUCTASE, Pharmacology, Toxicology and Pharmaceutics (miscellaneous), ACTIVATE, Reporter gene, drug repurposing, Chemistry, gene therapy, Imaging agent, In vitro, BIOREDUCTIVE PRODRUG PR-104A, PHASE-I, 030104 developmental biology, 030220 oncology & carcinogenesis, Cancer research, reporter gene imaging, Research Paper

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c62b726db7d1f04c1e9ab609dd8f61d1
http://europepmc.org/articles/PMC7482819

المؤلفون: Arthur Jochems, Jeff B. Smaill, Christopher P. Guise, Arne Heyerick, Maria R. Abbattista, Sophie Thiolloy, Amir Ashoorzadeh, Alexander M A van der Wiel, Kevin O. Hicks, Jan Theys, Ludwig Dubois, Philippe Lambin, Xiaojing Lin, Emily Liu, Robert F. Anderson, Zhe Fu, Damiënne Marcus, Victoria Jackson-Patel, Adam V. Patterson, Sisira Kumara, Ala Yaromina, Matthew Bull, Silvia Balbo, Morwena J. Solivio, R. Biemans, Sofie Deschoemaeker, Raymon Niemans, Alexandra M. Mowday, Natasja G. Lieuwes

المساهمون: Cellular and Molecular Immunology, Precision Medicine, RS: GROW - R3 - Innovative Cancer Diagnostics & Therapy, Radiotherapie, RS: GROW - R2 - Basic and Translational Cancer Biology

المصدر: Molecular Cancer Therapeutics, 20(12), 2372-2383. American Association for Cancer Research Inc.

مصطلحات موضوعية: Cancer Research, DOXORUBICIN, Reductase, Mice, In vivo, Animals, Humans, Prodrugs, OXIDOREDUCTASE, Cytotoxicity, COMBINATION, TH-302, REPAIR, Tumor hypoxia, IDENTIFICATION, Chemistry, Tumor Oxygenation, Prodrug, PR-104A, In vitro, PHASE-I, Oncology, Cell culture, Cancer research, MUSTARD, EVOFOSFAMIDE, Tumor Hypoxia

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8da436b0cdc3474a21aab13146be81dd
https://pubmed.ncbi.nlm.nih.gov/34625504

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المؤلفون: Janine N. Copp, Mathew A. Storey, Adam V. Patterson, Jeff B. Smaill, Laura K. Green, David F. Ackerley, Elsie M. Williams

المصدر: Cancers, Vol 5, Iss 3, Pp 985-997 (2013)
Cancers; Volume 5; Issue 3; Pages: 985-997
Cancers

مصطلحات موضوعية: Cancer Research, gene therapy, GDEPT, nitroaromatic prodrug, nitroreductase, CB1954, PR-104A, Nitro-CBI-DEI, SOS chromotest, Pharmacology, lcsh:RC254-282, Article, Nitroreductase, Therapeutic index, In vivo, Flavin reductase, Medicine, Cytotoxicity, chemistry.chemical_classification, business.industry, Prodrug, lcsh:Neoplasms. Tumors. Oncology. Including cancer and carcinogens, In vitro, Enzyme, Oncology, chemistry, Biochemistry, business

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c9ae07846a152e540ff955b7b6ad23eb
http://www.mdpi.com/2072-6694/5/3/985