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1دورية أكاديمية
المؤلفون: Shion A. Lim, Josef A. Gramespacher, Katarina Pance, Nicholas J. Rettko, Paige Solomon, Jing Jin, Irene Lui, Susanna K. Elledge, Jia Liu, Colton J. Bracken, Graham Simmons, Xin X. Zhou, Kevin K. Leung, James A. Wells
المصدر: mAbs, Vol 13, Iss 1 (2021)
مصطلحات موضوعية: Bispecific, neutralizing antibody, knob-in-hole, COVID-19, SARS-CoV-2, Therapeutics. Pharmacology, RM1-950, Immunologic diseases. Allergy, RC581-607
وصف الملف: electronic resource
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المؤلفون: Graham Simmons, Josef A. Gramespacher, Irene Lui, Shion A. Lim, Colton J Bracken, Jing Jin, Kevin Leung, Xin X. Zhou, Jia Liu, Paige Solomon, James A. Wells, Susanna K. Elledge, Nicholas J. Rettko, Katarina Pance
المصدر: mAbs
article-version (VoR) Version of Record
mAbs, vol 13, iss 1مصطلحات موضوعية: Phage display, Antibodies, Viral, Epitope, Neutralization, Epitopes, 0302 clinical medicine, Antibodies, Bispecific, Immunology and Allergy, Viral, Neutralizing antibody, Neutralizing, Lung, knob-in-hole, 0303 health sciences, biology, Chemistry, neutralizing antibody, Pharmacology and Pharmaceutical Sciences, Spike Glycoprotein, 5.1 Pharmaceuticals, 030220 oncology & carcinogenesis, Spike Glycoprotein, Coronavirus, Pneumonia & Influenza, Public Health and Health Services, Bispecific, Antibody, Biotechnology, Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), Immunology, Virus, Antibodies, Vaccine Related, 03 medical and health sciences, Immunoglobulin Fab Fragments, Clinical Research, Biodefense, Report, Potency, Humans, 030304 developmental biology, SARS-CoV-2, Prevention, COVID-19, Pneumonia, Virology, Antibodies, Neutralizing, COVID-19 Drug Treatment, Coronavirus, HEK293 Cells, biology.protein, Immunization
وصف الملف: application/pdf
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المؤلفون: James A. Wells, Rahul Aggarwal, Kevin Leung, Wentao Chen, Paige Solomon, Kurt Yun Mou
المصدر: Proc Natl Acad Sci U S A
مصطلحات موضوعية: Male, Cell type, B7 Antigens, T cell, Cell, Transfection, Natural killer cell, Proto-Oncogene Proteins c-myc, TNF-Related Apoptosis-Inducing Ligand, 03 medical and health sciences, 0302 clinical medicine, Cell Line, Tumor, Antibodies, Bispecific, medicine, Humans, Molecular Targeted Therapy, Cell Engineering, Transcription factor, B cell, 030304 developmental biology, B-Lymphocytes, 0303 health sciences, Multidisciplinary, Oncogene, Chemistry, Cytarabine, Prostate, Epithelial Cells, Biological Sciences, 3. Good health, Gene Expression Regulation, Neoplastic, Receptors, TNF-Related Apoptosis-Inducing Ligand, medicine.anatomical_structure, Cell culture, 030220 oncology & carcinogenesis, Cancer research, Immunotherapy, Immunosuppressive Agents, Plasmids, Protein Binding, Signal Transduction
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::943ee3311731571f458220cc775adabd
https://doi.org/10.1073/pnas.2018861118 -
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المؤلفون: Jeff E. Glasgow, Tanja Kortemme, Kevin Kao, Daniel Limonta, Paige Solomon, Rachel Yamin, Jeffrey V. Ravetch, Shoshana Zha, Anum A. Glasgow, Nicholas J. Rettko, Oren S. Rosenberg, Xin X. Zhou, Kevin Leung, James A. Wells, Yang Zhang, Shion A. Lim, Tom C. Hobman, Irene Lui, Arun P. Wiita, Matthew A. Nix
المصدر: Proceedings of the National Academy of Sciences
Proceedings of the National Academy of Sciences of the United States of America, vol 117, iss 45
bioRxiv, vol 1, iss 08-04
Proceedings of the National Academy of Sciences of the United States of Americaمصطلحات موضوعية: viruses, Plasma protein binding, Yeast display, Protein Engineering, 2.2 Factors relating to the physical environment, 2.1 Biological and endogenous factors, yeast display, Aetiology, Receptor, Lung, chemistry.chemical_classification, Multidisciplinary, biology, Biological Sciences, Entry into host, Recombinant Proteins, Spike Glycoprotein, Amino acid, Cell biology, Molecular Docking Simulation, Infectious Diseases, Pneumonia & Influenza, Angiotensin-Converting Enzyme 2, Antibody, Infection, hormones, hormone substitutes, and hormone antagonists, Biotechnology, Protein Binding, computational design, Mutagenesis (molecular biology technique), Saccharomyces cerevisiae, Antiviral Agents, Virus, receptor trap, Vaccine Related, Viral entry, Peptide Library, Biodefense, Humans, Avidity, Binding site, Binding Sites, SARS-CoV-2, Prevention, Pneumonia, antiviral therapeutics, Virology, Coronavirus, Biophysics and Computational Biology, Emerging Infectious Diseases, HEK293 Cells, chemistry, Drug Design, Mutation, biology.protein
وصف الملف: application/pdf
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b4a870c3a4385479cf71b200ef4430ee
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المؤلفون: Jie Zhou, Nicholas J. Rettko, Katarina Pance, Beth S. Zha, Irene Lui, Jia Liu, Duy P. Nguyen, James Byrnes, Kevin Leung, James A. Wells, Paige Solomon, Kaitlin Schaefer, Shion A. Lim, Colton J Bracken, Xin X. Zhou
المصدر: Nature Chemical Biology
Nature chemical biology, vol 17, iss 1مصطلحات موضوعية: Protein Conformation, Beta sheet, Plasma protein binding, Neutralization, Epitope, Protein structure, Models, Chlorocebus aethiops, Viral, Lung, Neutralizing, 0303 health sciences, biology, Chemistry, 030302 biochemistry & molecular biology, Spike Glycoprotein, Infectious Diseases, 5.1 Pharmaceuticals, Pneumonia & Influenza, Angiotensin-Converting Enzyme 2, Development of treatments and therapeutic interventions, Antibody, Protein Binding, Biochemistry & Molecular Biology, Stereochemistry, QCRG Structural Biology Consortium, Antibodies, Vaccine Related, 03 medical and health sciences, Medicinal and Biomolecular Chemistry, Clinical Research, Peptide Library, Biodefense, Animals, Humans, Protein Interaction Domains and Motifs, Binding site, Peptide library, Vero Cells, Molecular Biology, 030304 developmental biology, Binding Sites, SARS-CoV-2, Prevention, Cryoelectron Microscopy, alpha-Helical, Molecular, Pneumonia, Cell Biology, Coronavirus, Emerging Infectious Diseases, Good Health and Well Being, HEK293 Cells, biology.protein, beta-Strand, Biochemistry and Cell Biology, Single-Chain Antibodies
وصف الملف: application/pdf
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المؤلفون: Paige Solomon, Beth S. Zha, Jia Liu, James A. Wells, Katarina Pance, James Byrnes, Jie Zhou, Kevin Leung, Xin X. Zhou, Kaitlin Schaefer, Duy P. Nguyen, Nicholas J. Rettko, Irene Lui, Shion A. Lim, Colton J Bracken
المصدر: bioRxiv
article-version (status) pre
article-version (number) 1
Nature chemical biologyمصطلحات موضوعية: Models, Molecular, Protein Conformation, alpha-Helical, Coronavirus disease 2019 (COVID-19), Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), Antibodies, Viral, Neutralization, Epitope, Virus, Article, Peptide Library, Chlorocebus aethiops, Animals, Humans, Protein Interaction Domains and Motifs, Binding site, Vero Cells, Chemistry, SARS-CoV-2, Cryoelectron Microscopy, Antibodies, Neutralizing, Neutralizing epitope, HEK293 Cells, Spike Glycoprotein, Coronavirus, Biophysics, Protein Conformation, beta-Strand, Angiotensin-Converting Enzyme 2, Binding Sites, Antibody, Protein Binding, Single-Chain Antibodies
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e42a6899aff9c7d8f74d97b0876d29c6
http://europepmc.org/articles/PMC7430580 -
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المؤلفون: Frauke Muecksch, Nicholas J. Rettko, Fabian Schmidt, Paige Solomon, Shion A. Lim, Oren S. Rosenberg, Paul D. Bieniasz, Davide F. Robbiani, Beth S. Zha, Kevin Leung, James A. Wells, Jia Liu, Julio C. C. Lorenzi, Lisa L. Kirkemo, Josef A. Gramespacher, Theodora Hatziioannou, Susanna K. Elledge, Michel C. Nussenzweig, Yiska Weisblum, Xin X. Zhou, Irene Lui
مصطلحات موضوعية: Viral entry, law, Chemistry, Rational design, Biophysics, Recombinant DNA, Avidity, Context (language use), Spike (software development), Trimer, Receptor, hormones, hormone substitutes, and hormone antagonists, law.invention
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::0319142d11e9f08bb568cff79c3337d6
https://doi.org/10.1101/2020.05.21.109157 -
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المؤلفون: Paige Solomon, William F. DeGrado, Lijun Liu, Marco Mravic, Maxwell Tucker, Jessica L. Thomaston
المصدر: Science (New York, N.Y.), vol 363, iss 6434
Scienceمصطلحات موضوعية: Models, Molecular, Steric effects, Protein Structure, Secondary, Protein Folding, General Science & Technology, 1.1 Normal biological development and functioning, Synthetic membrane, Molecular Dynamics Simulation, Protein Engineering, Protein Structure, Secondary, Article, Hydrophobic effect, Protein structure, Models, Underpinning research, Side chain, Amino Acid Sequence, Multidisciplinary, Chemistry, Protein Stability, Calcium-Binding Proteins, Membrane Proteins, Molecular, Membrane, Membrane protein, Biophysics, Protein folding, Generic health relevance, Hydrophobic and Hydrophilic Interactions
وصف الملف: application/pdf
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e28adcae53fd58446a66217bc9703d4
https://escholarship.org/uc/item/6wb6c5zd -
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المؤلفون: Jenny Nelson, Paige Solomon
المصدر: Pharmaceutical development and technology. 23(3)
مصطلحات موضوعية: 0301 basic medicine, 010407 polymers, genetic structures, Pharmaceutical Science, Cataract formation, Eye, 01 natural sciences, Mass Spectrometry, Metal, 03 medical and health sciences, Impurity, Metals, Heavy, Ophthalmic drug, Inductively coupled plasma mass spectrometry, Drug Packaging, Chemistry, Metallome, food and beverages, Heavy metals, General Medicine, Contamination, eye diseases, 0104 chemical sciences, 030104 developmental biology, visual_art, Environmental chemistry, visual_art.visual_art_medium, Ophthalmic Solutions, Drug Contamination
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المؤلفون: Mark Anderson Jordi, Nina Chen, Syed Lateef, Paige Solomon, James Woods, Liuwei Jiang, Kevin Roland, Frankie Aiello, Samantha Martin, Jenny Nelson, Leland Martin, Smriti Khera
المصدر: Journal of pharmaceutical and biomedical analysis. 150
مصطلحات موضوعية: 0106 biological sciences, Polymers, Drug Compounding, Drug Storage, Clinical Biochemistry, Pharmaceutical Science, Mass spectrometry, 01 natural sciences, Gas Chromatography-Mass Spectrometry, Mass Spectrometry, Analytical Chemistry, Saline solutions, 010608 biotechnology, Drug Discovery, Calibration, Bioprocess, Process engineering, Disposable Equipment, Reference standards, Spectroscopy, Drug Packaging, Response factor, Automation, Laboratory, Biological Products, Single use, Models, Statistical, business.industry, Chemistry, 010401 analytical chemistry, Reproducibility of Results, Reference Standards, 0104 chemical sciences, Equipment Contamination, Gas chromatography–mass spectrometry, business, Drug Contamination, Chromatography, Liquid
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