المؤلفون: Pan H, Palekar RU, Hou KK, Bacon J, Yan H, Springer LE, Akk A, Yang L, Miller MJ, Pham CTN, Schlesinger PH, Wickline SA

المصدر: International Journal of Nanomedicine, Vol Volume 13, Pp 5187-5205 (2018)

مصطلحات موضوعية: siRNA, JNK2, peptide nanoparticles, perfluorocarbon nanoparticles, macrophages, atherosclerosis, plaque, ApoE-/- mice, thrombosis, endothelium, erosions, scavenger receptors, Medicine (General), R5-920

وصف الملف: electronic resource

Relation: https://www.dovepress.com/anti-jnk2-peptide-sirna-nanostructures-improve-plaque-endothelium-and--peer-reviewed-article-IJN; https://doaj.org/toc/1178-2013

URL الوصول: https://doaj.org/article/5d8337ba3ecc4ea281dbbda0cdcefd34

المؤلفون: Lai CT; Department of Chemistry, Northwestern University , Evanston, Illinois 60208, United States., Sun W; Department of Urology, Northwestern University , Chicago, Illinois 60611, United States.; Simpson Querrey Institute for Bionanotechnology , 303 East Superior, Chicago, Illinois 60611, United States.; International Institute for Nanotechnology, 2145 Sheridan Road, Evanston, Illinois 60208, United States., Palekar RU; Department of Urology, Northwestern University , Chicago, Illinois 60611, United States.; Simpson Querrey Institute for Bionanotechnology , 303 East Superior, Chicago, Illinois 60611, United States.; International Institute for Nanotechnology, 2145 Sheridan Road, Evanston, Illinois 60208, United States., Thaxton CS; Department of Urology, Northwestern University , Chicago, Illinois 60611, United States.; Simpson Querrey Institute for Bionanotechnology , 303 East Superior, Chicago, Illinois 60611, United States.; International Institute for Nanotechnology, 2145 Sheridan Road, Evanston, Illinois 60208, United States., Schatz GC; Department of Chemistry, Northwestern University , Evanston, Illinois 60208, United States.

المصدر: ACS applied materials & interfaces [ACS Appl Mater Interfaces] 2017 Jan 18; Vol. 9 (2), pp. 1247-1254. Date of Electronic Publication: 2017 Jan 05.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: American Chemical Society Country of Publication: United States NLM ID: 101504991 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1944-8252 (Electronic) Linking ISSN: 19448244 NLM ISO Abbreviation: ACS Appl Mater Interfaces Subsets: MEDLINE

مواضيع طبية MeSH: Metal Nanoparticles*, Cholesterol ; Gold ; Lipoproteins, HDL ; Molecular Dynamics Simulation

المؤلفون: Palekar RU; Department of Biomedical Engineering, Washington University in St. Louis, St. Louis, Mo., Vemuri C; Department of Surgery, Washington University in St. Louis, St. Louis, Mo., Marsh JN; Department of Medicine, Washington University in St. Louis, St. Louis, Mo., Arif B; Department of Surgery, Washington University in St. Louis, St. Louis, Mo., Wickline SA; Department of Biomedical Engineering, Washington University in St. Louis, St. Louis, Mo; Department of Medicine, Washington University in St. Louis, St. Louis, Mo. Electronic address: wicklines@aol.com.

المصدر: Journal of vascular surgery [J Vasc Surg] 2016 Nov; Vol. 64 (5), pp. 1459-1467. Date of Electronic Publication: 2015 Oct 17.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Elsevier Country of Publication: United States NLM ID: 8407742 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1097-6809 (Electronic) Linking ISSN: 07415214 NLM ISO Abbreviation: J Vasc Surg Subsets: MEDLINE

مواضيع طبية MeSH: Drug Carriers* , Nanoparticles* , Stents*, Amino Acid Chloromethyl Ketones/*pharmacology , Antithrombins/*pharmacology , Blood Coagulation/*drug effects , Fluorocarbons/*chemistry , Percutaneous Coronary Intervention/*instrumentation , Thrombosis/*prevention & control, Amino Acid Chloromethyl Ketones/chemistry ; Antithrombins/chemistry ; Blood Flow Velocity ; Cells, Cultured ; Endothelial Cells/drug effects ; Endothelial Cells/metabolism ; Humans ; Percutaneous Coronary Intervention/adverse effects ; Prosthesis Design ; Stainless Steel ; Surface Properties ; Thrombosis/blood ; Thrombosis/etiology ; Thrombosis/physiopathology ; Time Factors

المؤلفون: Palekar RU; From the Department of Biomedical Engineering (R.U.P., S.A.W.), and Department of Medicine (A.P.J., H.P., S.A.W.), Washington University in St Louis, MO; and Department of Pharmacology, University of Pennsylvania, Philadelphia (J.W.M.)., Jallouk AP; From the Department of Biomedical Engineering (R.U.P., S.A.W.), and Department of Medicine (A.P.J., H.P., S.A.W.), Washington University in St Louis, MO; and Department of Pharmacology, University of Pennsylvania, Philadelphia (J.W.M.)., Myerson JW; From the Department of Biomedical Engineering (R.U.P., S.A.W.), and Department of Medicine (A.P.J., H.P., S.A.W.), Washington University in St Louis, MO; and Department of Pharmacology, University of Pennsylvania, Philadelphia (J.W.M.)., Pan H; From the Department of Biomedical Engineering (R.U.P., S.A.W.), and Department of Medicine (A.P.J., H.P., S.A.W.), Washington University in St Louis, MO; and Department of Pharmacology, University of Pennsylvania, Philadelphia (J.W.M.)., Wickline SA; From the Department of Biomedical Engineering (R.U.P., S.A.W.), and Department of Medicine (A.P.J., H.P., S.A.W.), Washington University in St Louis, MO; and Department of Pharmacology, University of Pennsylvania, Philadelphia (J.W.M.). wicklines@aol.com.

المصدر: Arteriosclerosis, thrombosis, and vascular biology [Arterioscler Thromb Vasc Biol] 2016 Mar; Vol. 36 (3), pp. 446-55. Date of Electronic Publication: 2016 Jan 14.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural

بيانات الدورية: Publisher: Lippincott Williams & Wilkins Country of Publication: United States NLM ID: 9505803 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1524-4636 (Electronic) Linking ISSN: 10795642 NLM ISO Abbreviation: Arterioscler Thromb Vasc Biol Subsets: MEDLINE

مواضيع طبية MeSH: Nanoparticles*, Amino Acid Chloromethyl Ketones/*pharmacology , Antithrombins/*pharmacology , Atherosclerosis/*drug therapy , Capillary Permeability/*drug effects , Carotid Artery Injuries/*drug therapy , Endothelium, Vascular/*drug effects , Thrombin/*antagonists & inhibitors , Thrombosis/*prevention & control, Amino Acid Chloromethyl Ketones/pharmacokinetics ; Animals ; Antithrombins/pharmacokinetics ; Apolipoproteins E/deficiency ; Apolipoproteins E/genetics ; Atherosclerosis/genetics ; Atherosclerosis/metabolism ; Atherosclerosis/pathology ; Blood Coagulation/drug effects ; Carotid Artery Injuries/metabolism ; Carotid Artery Injuries/pathology ; Cells, Cultured ; Diet, High-Fat ; Disease Models, Animal ; Endothelial Cells/drug effects ; Endothelial Cells/metabolism ; Endothelial Cells/pathology ; Endothelium, Vascular/metabolism ; Endothelium, Vascular/pathology ; Humans ; Inflammation Mediators/metabolism ; Magnetic Resonance Spectroscopy ; Male ; Mice, Knockout ; Plaque, Atherosclerotic ; Signal Transduction/drug effects ; Thrombin/metabolism ; Thrombosis/genetics ; Thrombosis/metabolism ; Thrombosis/pathology ; Time Factors

المؤلفون: Jallouk AP; †Consortium for Translational Research in Advanced Imaging and Nanomedicine, Division of Cardiology, Department of Medicine, Washington University in St. Louis School of Medicine, St. Louis, Missouri 63108, United States., Palekar RU; †Consortium for Translational Research in Advanced Imaging and Nanomedicine, Division of Cardiology, Department of Medicine, Washington University in St. Louis School of Medicine, St. Louis, Missouri 63108, United States., Marsh JN; †Consortium for Translational Research in Advanced Imaging and Nanomedicine, Division of Cardiology, Department of Medicine, Washington University in St. Louis School of Medicine, St. Louis, Missouri 63108, United States., Pan H; †Consortium for Translational Research in Advanced Imaging and Nanomedicine, Division of Cardiology, Department of Medicine, Washington University in St. Louis School of Medicine, St. Louis, Missouri 63108, United States., Pham CT, Schlesinger PH, Wickline SA; †Consortium for Translational Research in Advanced Imaging and Nanomedicine, Division of Cardiology, Department of Medicine, Washington University in St. Louis School of Medicine, St. Louis, Missouri 63108, United States.

المصدر: Bioconjugate chemistry [Bioconjug Chem] 2015 Aug 19; Vol. 26 (8), pp. 1640-50. Date of Electronic Publication: 2015 Jul 02.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.

بيانات الدورية: Publisher: American Chemical Society Country of Publication: United States NLM ID: 9010319 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1520-4812 (Electronic) Linking ISSN: 10431802 NLM ISO Abbreviation: Bioconjug Chem Subsets: MEDLINE

مواضيع طبية MeSH: Drug Delivery Systems*, Fluorocarbons/*chemistry , Matrix Metalloproteinase 9/*metabolism , Melitten/*pharmacology , Nanoparticles/*administration & dosage , Peptide Fragments/*chemistry , Prodrugs/*chemistry , Prodrugs/*pharmacology, Animals ; Hemolysis/drug effects ; Humans ; Mass Spectrometry ; Melanoma, Experimental ; Melitten/chemistry ; Mice ; Mice, Inbred C57BL ; Nanoparticles/chemistry ; Rabbits

المؤلفون: Palekar RU; Department of Biomedical Engineering and Department of Medicine, Washington University, St. Louis, Missouri, USA., Jallouk AP; Department of Biomedical Engineering and Department of Medicine, Washington University, St. Louis, Missouri, USA., Goette MJ; Department of Biomedical Engineering and Department of Medicine, Washington University, St. Louis, Missouri, USA., Chen J; Department of Biomedical Engineering and Department of Medicine, Washington University, St. Louis, Missouri, USA., Myerson JW; Department of Biomedical Engineering and Department of Medicine, Washington University, St. Louis, Missouri, USA., Allen JS; Department of Biomedical Engineering and Department of Medicine, Washington University, St. Louis, Missouri, USA., Akk A; Department of Biomedical Engineering and Department of Medicine, Washington University, St. Louis, Missouri, USA., Yang L; Department of Biomedical Engineering and Department of Medicine, Washington University, St. Louis, Missouri, USA., Tu Y; Department of Biomedical Engineering and Department of Medicine, Washington University, St. Louis, Missouri, USA., Miller MJ; Department of Biomedical Engineering and Department of Medicine, Washington University, St. Louis, Missouri, USA., Pham CT; Department of Biomedical Engineering and Department of Medicine, Washington University, St. Louis, Missouri, USA., Wickline SA; Department of Biomedical Engineering and Department of Medicine, Washington University, St. Louis, Missouri, USA wicklines@aol.com hpan@dom.wustl.edu., Pan H; Department of Biomedical Engineering and Department of Medicine, Washington University, St. Louis, Missouri, USA wicklines@aol.com hpan@dom.wustl.edu.

المصدر: FASEB journal : official publication of the Federation of American Societies for Experimental Biology [FASEB J] 2015 Jul; Vol. 29 (7), pp. 3100-9. Date of Electronic Publication: 2015 Apr 09.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Federation of American Societies for Experimental Biology Country of Publication: United States NLM ID: 8804484 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1530-6860 (Electronic) Linking ISSN: 08926638 NLM ISO Abbreviation: FASEB J Subsets: MEDLINE

مواضيع طبية MeSH: Atherosclerosis/*complications , Thrombosis/*etiology, Animals ; Apolipoproteins E/deficiency ; Apolipoproteins E/genetics ; Atherosclerosis/diet therapy ; Atherosclerosis/etiology ; Capillary Permeability ; Cholesterol/chemistry ; Cholesterol/metabolism ; Crystallization ; Diet, Atherogenic/adverse effects ; Diet, Western/adverse effects ; Disease Models, Animal ; Disease Progression ; Endothelium, Vascular/pathology ; Endothelium, Vascular/physiopathology ; Fluorocarbons ; Magnetic Resonance Imaging ; Male ; Mice ; Mice, Knockout ; Nanoparticles ; Plaque, Atherosclerotic/complications ; Plaque, Atherosclerotic/diagnosis ; Rabbits ; Risk Factors

المؤلفون: Chen J; Department of Medicine, Washington University, St. Louis, Missouri;, Vemuri C; Department of Medicine, Washington University, St. Louis, Missouri; Department of Surgery, Washington University, St. Louis, Missouri;, Palekar RU; Department of Medicine, Washington University, St. Louis, Missouri; Department of Biomedical Engineering, Washington University, St. Louis, Missouri; and., Gaut JP; Department of Pathology and Immunology, Washington University, St. Louis, Missouri., Goette M; Department of Medicine, Washington University, St. Louis, Missouri; Department of Biomedical Engineering, Washington University, St. Louis, Missouri; and., Hu L; Department of Medicine, Washington University, St. Louis, Missouri;, Cui G; Department of Medicine, Washington University, St. Louis, Missouri;, Zhang H; Department of Medicine, Washington University, St. Louis, Missouri;, Wickline SA; Department of Medicine, Washington University, St. Louis, Missouri; Department of Biomedical Engineering, Washington University, St. Louis, Missouri; and saw@wuphysics.wustl.edu.

المصدر: American journal of physiology. Renal physiology [Am J Physiol Renal Physiol] 2015 Apr 01; Vol. 308 (7), pp. F765-73. Date of Electronic Publication: 2015 Jan 28.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural

بيانات الدورية: Publisher: American Physiological Society Country of Publication: United States NLM ID: 100901990 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1522-1466 (Electronic) Linking ISSN: 15221466 NLM ISO Abbreviation: Am J Physiol Renal Physiol Subsets: MEDLINE

مواضيع طبية MeSH: Acute Kidney Injury/*drug therapy , Cysteine Proteinase Inhibitors/*pharmacology , Endothelial Cells/*drug effects , Magnetite Nanoparticles/*administration & dosage , Reperfusion Injury/*drug therapy , Thrombin/*antagonists & inhibitors, Acute Kidney Injury/pathology ; Amino Acid Chloromethyl Ketones/pharmacology ; Animals ; Cells, Cultured ; Creatinine/urine ; Disease Models, Animal ; Endothelial Cells/pathology ; Inflammation/drug therapy ; Male ; Mice, Inbred C57BL ; Reperfusion Injury/pathology

المؤلفون: Jallouk AP; Consortium for Translational Research in Advanced Imaging and Nanomedicine, Department of Medicine, Division of Cardiology, Washington University in St. Louis, St. Louis, Missouri, USA., Palekar RU; Consortium for Translational Research in Advanced Imaging and Nanomedicine, Department of Medicine, Division of Cardiology, Washington University in St. Louis, St. Louis, Missouri, USA., Pan H; Consortium for Translational Research in Advanced Imaging and Nanomedicine, Department of Medicine, Division of Cardiology, Washington University in St. Louis, St. Louis, Missouri, USA., Schlesinger PH; Department of Cell Biology and Physiology, Washington University in St. Louis, St. Louis, Missouri, USA., Wickline SA; Consortium for Translational Research in Advanced Imaging and Nanomedicine, Department of Medicine, Division of Cardiology, Washington University in St. Louis, St. Louis, Missouri, USA; Department of Cell Biology and Physiology, Washington University in St. Louis, St. Louis, Missouri, USA. Electronic address: wicklines@aol.com.

المصدر: Advances in protein chemistry and structural biology [Adv Protein Chem Struct Biol] 2015; Vol. 98, pp. 57-91. Date of Electronic Publication: 2015 Mar 12.

نوع المنشور: Journal Article; Review

بيانات الدورية: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 101497281 Publication Model: Print-Electronic Cited Medium: Print ISSN: 1876-1623 (Print) Linking ISSN: 18761623 NLM ISO Abbreviation: Adv Protein Chem Struct Biol Subsets: MEDLINE

مواضيع طبية MeSH: Drug Design*, Cell-Penetrating Peptides/*chemistry , Drug Delivery Systems/*methods , Nanoparticles/*chemistry , Toxins, Biological/*chemistry, Amino Acid Sequence ; Animals ; Biological Products/chemistry ; Biological Products/pharmacology ; Cell-Penetrating Peptides/pharmacology ; Humans ; Molecular Sequence Data ; Nanoparticles/ultrastructure ; Toxins, Biological/toxicity

المؤلفون: Palekar RU; Department of Biomedical Engineering, Washington University, Whitaker Hall, Campus Box 1097, One Brookings Drive, St. Louis, MO 63130, USA., Jallouk AP; Department of Medicine, Washington University, Campus Box 8215, 4320 Forest Park Avenue, St Louis, MO 63108, USA., Lanza GM; Department of Biomedical Engineering, Washington University, Whitaker Hall, Campus Box 1097, One Brookings Drive, St. Louis, MO 63130, USA.; Department of Medicine, Washington University, Campus Box 8215, 4320 Forest Park Avenue, St Louis, MO 63108, USA., Pan H; Department of Medicine, Washington University, Campus Box 8215, 4320 Forest Park Avenue, St Louis, MO 63108, USA., Wickline SA; Department of Biomedical Engineering, Washington University, Whitaker Hall, Campus Box 1097, One Brookings Drive, St. Louis, MO 63130, USA.; Department of Medicine, Washington University, Campus Box 8215, 4320 Forest Park Avenue, St Louis, MO 63108, USA.

المصدر: Nanomedicine (London, England) [Nanomedicine (Lond)] 2015; Vol. 10 (11), pp. 1817-32.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Review

بيانات الدورية: Publisher: Future Medicine Ltd Country of Publication: England NLM ID: 101278111 Publication Model: Print Cited Medium: Internet ISSN: 1748-6963 (Electronic) Linking ISSN: 17435889 NLM ISO Abbreviation: Nanomedicine (Lond) Subsets: MEDLINE

مواضيع طبية MeSH: Atherosclerosis/*diagnostic imaging , Contrast Media/*therapeutic use , Nanoparticles/*therapeutic use , Plaque, Atherosclerotic/*diagnostic imaging, Atherosclerosis/pathology ; Contrast Media/chemistry ; Humans ; Magnetic Resonance Imaging/methods ; Molecular Imaging/methods ; Plaque, Atherosclerotic/pathology ; Radiography

المؤلفون: Palekar RU; Department of Biomedical Engineering, ‡Department of Cell Biology and Physiology, §Department of Medicine, and ∥Department of Physics, Washington University in St. Louis, Consortium for Translational Research in Advanced Imaging and Nanomedicine , 4320 Forest Park Avenue, St. Louis, Missouri 63108, United States., Myerson JW, Schlesinger PH, Sadler JE, Pan H, Wickline SA

المصدر: Molecular pharmaceutics [Mol Pharm] 2013 Nov 04; Vol. 10 (11), pp. 4168-75. Date of Electronic Publication: 2013 Oct 10.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural

بيانات الدورية: Publisher: American Chemical Society Country of Publication: United States NLM ID: 101197791 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1543-8392 (Electronic) Linking ISSN: 15438384 NLM ISO Abbreviation: Mol Pharm Subsets: MEDLINE

مواضيع طبية MeSH: Anticoagulants/*chemistry , Anticoagulants/*therapeutic use , Liposomes/*chemistry , Thrombin/*chemistry , Thrombin/*metabolism , Thrombosis/*drug therapy, Amino Acid Chloromethyl Ketones/chemistry ; Animals ; Humans ; Mice ; Unilamellar Liposomes/chemistry