المؤلفون: Haston, S, Gonzalez-Gualda, E, Morsil, S, Ge, J, Reen, V, Calderwood, A, Moutsopoulos, I, Panousopoulos, L, Deletc, P, Carreno, G, Guiho, R, Manshaei, S, Gonzalez-Meljem, JM, Lim, HY, Simpson, DJ, Birch, J, Pallikonda, HA, Chandra, T, Macias, D, Doherty, GJ, Rassl, DM, Rintoul, RC, Signore, M, Mohorianu, I, Akbar, AN, Gil, J, Munoz-Espín, D, Martinez-Barbera, JP

المصدر: 1260.e6

URL الوصول: https://explore.openaire.eu/search/publication?articleId=od______1032::a97444084fe123ef47c65398e23e84d0
http://hdl.handle.net/10044/1/104446

المؤلفون: Haston S; Developmental Biology and Cancer Programme, Birth Defects Research Centre, UCL Institute of Child Health, London WC1N 1EH, UK. Electronic address: scott.haston.13@ucl.ac.uk., Gonzalez-Gualda E; Early Cancer Institute, Department of Oncology, University of Cambridge, Cambridge, UK., Morsli S; Early Cancer Institute, Department of Oncology, University of Cambridge, Cambridge, UK., Ge J; Early Cancer Institute, Department of Oncology, University of Cambridge, Cambridge, UK., Reen V; MRC London Institute of Medical Sciences (LMS), Du Cane Road, London W12 0NN, UK; Institute of Clinical Sciences (ICS), Faculty of Medicine, Imperial College London, Du Cane Road, London W12 0NN, UK., Calderwood A; Wellcome-MRC Cambridge Stem Cell Institute, Jeffrey Cheah Biomedical Centre, University of Cambridge, Cambridge CB2 0AW, UK., Moutsopoulos I; Wellcome-MRC Cambridge Stem Cell Institute, Jeffrey Cheah Biomedical Centre, University of Cambridge, Cambridge CB2 0AW, UK., Panousopoulos L; Developmental Biology and Cancer Programme, Birth Defects Research Centre, UCL Institute of Child Health, London WC1N 1EH, UK., Deletic P; Division of Medicine, University College London, London, UK., Carreno G; Developmental Biology and Cancer Programme, Birth Defects Research Centre, UCL Institute of Child Health, London WC1N 1EH, UK., Guiho R; Developmental Biology and Cancer Programme, Birth Defects Research Centre, UCL Institute of Child Health, London WC1N 1EH, UK., Manshaei S; Developmental Biology and Cancer Programme, Birth Defects Research Centre, UCL Institute of Child Health, London WC1N 1EH, UK., Gonzalez-Meljem JM; Tecnologico de Monterrey, School of Engineering and Sciences, Mexico City, Mexico., Lim HY; Developmental Biology and Cancer Programme, Birth Defects Research Centre, UCL Institute of Child Health, London WC1N 1EH, UK., Simpson DJ; MRC Human Generics Unit, University of Edinburgh, Edinburgh, UK., Birch J; MRC London Institute of Medical Sciences (LMS), Du Cane Road, London W12 0NN, UK; Institute of Clinical Sciences (ICS), Faculty of Medicine, Imperial College London, Du Cane Road, London W12 0NN, UK., Pallikonda HA; MRC London Institute of Medical Sciences (LMS), Du Cane Road, London W12 0NN, UK; Institute of Clinical Sciences (ICS), Faculty of Medicine, Imperial College London, Du Cane Road, London W12 0NN, UK., Chandra T; MRC Human Generics Unit, University of Edinburgh, Edinburgh, UK., Macias D; Early Cancer Institute, Department of Oncology, University of Cambridge, Cambridge, UK., Doherty GJ; Cambridge University Hospitals NHS Foundation Trust, Department of Oncology, Addenbrooke's Hospital, Cambridge CB2 0QQ, UK., Rassl DM; Royal Papworth Hospital NHS Foundation Trust. Cambridge Biomedical Campus, Cambridge CB2 0AY, UK., Rintoul RC; Royal Papworth Hospital NHS Foundation Trust. Cambridge Biomedical Campus, Cambridge CB2 0AY, UK; Department of Oncology, University of Cambridge, Cambridge, UK; CRUK Cambridge Centre Thoracic Cancer Programme, Cambridge, UK., Signore M; Developmental Biology and Cancer Programme, Birth Defects Research Centre, UCL Institute of Child Health, London WC1N 1EH, UK., Mohorianu I; Wellcome-MRC Cambridge Stem Cell Institute, Jeffrey Cheah Biomedical Centre, University of Cambridge, Cambridge CB2 0AW, UK., Akbar AN; Division of Medicine, University College London, London, UK., Gil J; MRC London Institute of Medical Sciences (LMS), Du Cane Road, London W12 0NN, UK; Institute of Clinical Sciences (ICS), Faculty of Medicine, Imperial College London, Du Cane Road, London W12 0NN, UK., Muñoz-Espín D; Early Cancer Institute, Department of Oncology, University of Cambridge, Cambridge, UK; CRUK Cambridge Centre Thoracic Cancer Programme, Cambridge, UK. Electronic address: dm742@cam.ac.uk., Martinez-Barbera JP; Developmental Biology and Cancer Programme, Birth Defects Research Centre, UCL Institute of Child Health, London WC1N 1EH, UK. Electronic address: j.martinez-barbera@ucl.ac.uk.

المصدر: Cancer cell [Cancer Cell] 2023 Jul 10; Vol. 41 (7), pp. 1242-1260.e6. Date of Electronic Publication: 2023 Jun 01.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Cell Press Country of Publication: United States NLM ID: 101130617 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1878-3686 (Electronic) Linking ISSN: 15356108 NLM ISO Abbreviation: Cancer Cell Subsets: MEDLINE

مواضيع طبية MeSH: Cellular Senescence*/genetics , Lung Neoplasms*/genetics , Lung Neoplasms*/metabolism, Aged ; Animals ; Humans ; Mice ; Carcinogenesis/genetics ; Carcinogenesis/metabolism ; Endothelial Cells ; Macrophages/metabolism ; Proto-Oncogene Proteins p21(ras)/genetics ; Proto-Oncogene Proteins p21(ras)/metabolism ; Tumor Microenvironment

المؤلفون: Spain L; Cancer Dynamics Laboratory, The Francis Crick Institute, London, United Kingdom.; Skin and Renal Unit, Royal Marsden NHS Foundation Trust, London, United Kingdom.; Department of Medical Oncology, Peter MacCallum Cancer -Centre, Melbourne, Australia., Coulton A; Cancer Dynamics Laboratory, The Francis Crick Institute, London, United Kingdom.; Tumour Immunogenomics and Immunosurveillance (TIGI) Lab, UCL Cancer Institute, London, United Kingdom., Lobon I; Cancer Dynamics Laboratory, The Francis Crick Institute, London, United Kingdom., Rowan A; Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute, London, United Kingdom., Schnidrig D; Cancer Dynamics Laboratory, The Francis Crick Institute, London, United Kingdom., Shepherd STC; Cancer Dynamics Laboratory, The Francis Crick Institute, London, United Kingdom.; Skin and Renal Unit, Royal Marsden NHS Foundation Trust, London, United Kingdom., Shum B; Cancer Dynamics Laboratory, The Francis Crick Institute, London, United Kingdom.; Skin and Renal Unit, Royal Marsden NHS Foundation Trust, London, United Kingdom., Byrne F; Cancer Dynamics Laboratory, The Francis Crick Institute, London, United Kingdom., Goicoechea M; Cancer Dynamics Laboratory, The Francis Crick Institute, London, United Kingdom., Piperni E; Cancer Dynamics Laboratory, The Francis Crick Institute, London, United Kingdom., Au L; Cancer Dynamics Laboratory, The Francis Crick Institute, London, United Kingdom.; Skin and Renal Unit, Royal Marsden NHS Foundation Trust, London, United Kingdom.; Department of Medical Oncology, Peter MacCallum Cancer -Centre, Melbourne, Australia.; Sir Peter MacCallum Department of Oncology, The University of Melbourne, Victoria, Australia., Edmonds K; The Royal Marsden Hospital, London, United Kingdom., Carlyle E; The Royal Marsden Hospital, London, United Kingdom., Hunter N; The Royal Marsden Hospital, London, United Kingdom., Renn A; The Royal Marsden Hospital, London, United Kingdom., Messiou C; The Royal Marsden Hospital, London, United Kingdom.; The Institute of Cancer Research, Kensington and Chelsea, United Kingdom., Hughes P; Skin and Renal Unit, Royal Marsden NHS Foundation Trust, London, United Kingdom., Nobbs J; Skin and Renal Unit, Royal Marsden NHS Foundation Trust, London, United Kingdom., Foijer F; European Research Institute for the Biology of Ageing, University of Groningen, University Medical Centre Groningen, Groningen, the Netherlands., van den Bos H; European Research Institute for the Biology of Ageing, University of Groningen, University Medical Centre Groningen, Groningen, the Netherlands., Wardenaar R; European Research Institute for the Biology of Ageing, University of Groningen, University Medical Centre Groningen, Groningen, the Netherlands., Spierings DCJ; European Research Institute for the Biology of Ageing, University of Groningen, University Medical Centre Groningen, Groningen, the Netherlands., Spencer C; Cancer Dynamics Laboratory, The Francis Crick Institute, London, United Kingdom.; Skin and Renal Unit, Royal Marsden NHS Foundation Trust, London, United Kingdom., Schmitt AM; The Royal Marsden Hospital, London, United Kingdom., Tippu Z; Cancer Dynamics Laboratory, The Francis Crick Institute, London, United Kingdom.; Skin and Renal Unit, Royal Marsden NHS Foundation Trust, London, United Kingdom., Lingard K; The Royal Marsden Hospital, London, United Kingdom., Grostate L; The Royal Marsden Hospital, London, United Kingdom., Peat K; The Royal Marsden Hospital, London, United Kingdom., Kelly K; The Royal Marsden Hospital, London, United Kingdom., Sarker S; The Royal Marsden Hospital, London, United Kingdom., Vaughan S; The Royal Marsden Hospital, London, United Kingdom., Mangwende M; The Royal Marsden Hospital, London, United Kingdom., Terry L; The Royal Marsden Hospital, London, United Kingdom., Kelly D; The Royal Marsden Hospital, London, United Kingdom., Biano J; The Royal Marsden Hospital, London, United Kingdom., Murra A; The Royal Marsden Hospital, London, United Kingdom., Korteweg J; The Royal Marsden Hospital, London, United Kingdom., Lewis C; The Royal Marsden Hospital, London, United Kingdom., O'Flaherty M; The Royal Marsden Hospital, London, United Kingdom., Cattin AL; Cancer Dynamics Laboratory, The Francis Crick Institute, London, United Kingdom., Emmerich M; Cancer Dynamics Laboratory, The Francis Crick Institute, London, United Kingdom.; St. John's Institute of Dermatology, Guy's and St Thomas' Hospital NHS Foundation Trust, London, United Kingdom., Gerard CL; Cancer Dynamics Laboratory, The Francis Crick Institute, London, United Kingdom.; Precision Oncology Center, Oncology Department, Lausanne University Hospital, Lausanne, Switzerland., Pallikonda HA; Cancer Dynamics Laboratory, The Francis Crick Institute, London, United Kingdom., Lynch J; The Royal Marsden Hospital, London, United Kingdom., Mason R; Gold Coast University Hospital, Queensland, Australia., Rogiers A; Cancer Dynamics Laboratory, The Francis Crick Institute, London, United Kingdom.; The Royal Marsden Hospital, London, United Kingdom., Xu H; The Francis Crick Institute, London, United Kingdom., Huebner A; Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute, London, United Kingdom.; Cancer Genome Evolution Research Group, Cancer Research UK Lung Cancer Centre of Excellence, UCL Cancer Institute, London, United Kingdom.; Cancer Research UK Lung Cancer Centre of Excellence, UCL Cancer Institute, London, United Kingdom., McGranahan N; Cancer Genome Evolution Research Group, Cancer Research UK Lung Cancer Centre of Excellence, UCL Cancer Institute, London, United Kingdom., Al Bakir M; Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute, London, United Kingdom.; Cancer Research UK Lung Cancer Centre of Excellence, UCL Cancer Institute, London, United Kingdom., Murai J; Tumour Immunogenomics and Immunosurveillance (TIGI) Lab, UCL Cancer Institute, London, United Kingdom.; Drug Discovery Technology Laboratories, Ono Pharmaceutical Co., Ltd. Osaka, Japan., Naceur-Lombardelli C; Cancer Research UK Lung Cancer Centre of Excellence, UCL Cancer Institute, London, United Kingdom., Borg E; University College London Hospital, London, United Kingdom., Mitchison M; University College London Hospital, London, United Kingdom., Moore DA; Guy's and St Thomas' NHS Foundation Trust, London, United Kingdom., Falzon M; University College London Hospital, London, United Kingdom., Proctor I; University College London Hospital, London, United Kingdom., Stamp GWH; The Francis Crick Institute, London, United Kingdom., Nye EL; The Francis Crick Institute, London, United Kingdom., Young K; Skin and Renal Unit, Royal Marsden NHS Foundation Trust, London, United Kingdom., Furness AJS; Skin and Renal Unit, Royal Marsden NHS Foundation Trust, London, United Kingdom.; The Institute of Cancer Research, Kensington and Chelsea, United Kingdom., Pickering L; The Royal Marsden Hospital, London, United Kingdom., Stewart R; Guy's and St Thomas' NHS Foundation Trust, London, United Kingdom., Mahadeva U; Guy's and St Thomas' NHS Foundation Trust, London, United Kingdom., Green A; Guy's and St Thomas' NHS Foundation Trust, London, United Kingdom., Larkin J; Guy's and St Thomas' NHS Foundation Trust, London, United Kingdom., Litchfield K; Tumour Immunogenomics and Immunosurveillance (TIGI) Lab, UCL Cancer Institute, London, United Kingdom., Swanton C; Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute, London, United Kingdom., Jamal-Hanjani M; Cancer Research UK Lung Cancer Centre of Excellence, UCL Cancer Institute, London, United Kingdom.; Cancer Metastasis Laboratory, University College London Cancer Institute, London, United Kingdom.; Department of Medical Oncology, University College London Hospitals, London, United Kingdom., Turajlic S; Cancer Dynamics Laboratory, The Francis Crick Institute, London, United Kingdom.; Skin and Renal Unit, Royal Marsden NHS Foundation Trust, London, United Kingdom.

مؤلفون مشاركون: PEACE Consortium

المصدر: Cancer discovery [Cancer Discov] 2023 Jun 02; Vol. 13 (6), pp. 1364-1385.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: American Association for Cancer Research Country of Publication: United States NLM ID: 101561693 Publication Model: Print Cited Medium: Internet ISSN: 2159-8290 (Electronic) Linking ISSN: 21598274 NLM ISO Abbreviation: Cancer Discov Subsets: MEDLINE

مواضيع طبية MeSH: Melanoma*/pathology , Brain Neoplasms*, Humans ; Mutation ; Evolution, Molecular ; DNA

المؤلفون: Pallikonda HA; Cancer Dynamics Laboratory, The Francis Crick Institute, London, United Kingdom., Turajlic S; Cancer Dynamics Laboratory, The Francis Crick Institute, London, United Kingdom; Skin and Renal Units, The Royal Marsden NHS Foundation Trust, London, United Kingdom; Melanoma and Kidney Cancer Team, Institute of Cancer Research, London, United Kingdom. Electronic address: samra.turajlic@crick.ac.uk.

المصدر: Biochimica et biophysica acta. Reviews on cancer [Biochim Biophys Acta Rev Cancer] 2022 Sep; Vol. 1877 (5), pp. 188759. Date of Electronic Publication: 2022 Jul 11.

نوع المنشور: Journal Article; Review; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural

بيانات الدورية: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 9806362 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-2561 (Electronic) Linking ISSN: 0304419X NLM ISO Abbreviation: Biochim Biophys Acta Rev Cancer Subsets: MEDLINE

مواضيع طبية MeSH: Carcinoma, Renal Cell*/genetics , Carcinoma, Renal Cell*/pathology , Kidney Neoplasms*/genetics , Kidney Neoplasms*/pathology, Humans

المؤلفون: Karimi MM; MRC London Institute of Medical Sciences, Institute of Clinical Sciences, Faculty of Medicine, Imperial College London, London, UK.; Comprehensive Cancer Centre, School of Cancer & Pharmaceutical Sciences, Faculty of Life Sciences & Medicine, King's College London, London, UK., Guo Y; MRC London Institute of Medical Sciences, Institute of Clinical Sciences, Faculty of Medicine, Imperial College London, London, UK.; School of Life Sciences and Biotechnology, Shanghai Jiao Tong University, Shanghai, China., Cui X; MRC London Institute of Medical Sciences, Institute of Clinical Sciences, Faculty of Medicine, Imperial College London, London, UK., Pallikonda HA; MRC London Institute of Medical Sciences, Institute of Clinical Sciences, Faculty of Medicine, Imperial College London, London, UK., Horková V; Laboratory of Adaptive Immunity, Institute of Molecular Genetics of the Czech Academy of Sciences, Prague, Czech Republic., Wang YF; MRC London Institute of Medical Sciences, Institute of Clinical Sciences, Faculty of Medicine, Imperial College London, London, UK., Gil SR; CNAG-CRG, Centre for Genomic Regulation (CRG), The Barcelona Institute of Science and Technology (BIST), Barcelona, Spain., Rodriguez-Esteban G; CNAG-CRG, Centre for Genomic Regulation (CRG), The Barcelona Institute of Science and Technology (BIST), Barcelona, Spain., Robles-Rebollo I; MRC London Institute of Medical Sciences, Institute of Clinical Sciences, Faculty of Medicine, Imperial College London, London, UK., Bruno L; MRC London Institute of Medical Sciences, Institute of Clinical Sciences, Faculty of Medicine, Imperial College London, London, UK., Georgieva R; MRC London Institute of Medical Sciences, Institute of Clinical Sciences, Faculty of Medicine, Imperial College London, London, UK., Patel B; MRC London Institute of Medical Sciences, Institute of Clinical Sciences, Faculty of Medicine, Imperial College London, London, UK., Elliott J; MRC London Institute of Medical Sciences, Institute of Clinical Sciences, Faculty of Medicine, Imperial College London, London, UK., Dore MH; MRC London Institute of Medical Sciences, Institute of Clinical Sciences, Faculty of Medicine, Imperial College London, London, UK., Dauphars D; Department of Immunology, Duke University Medical Center, Durham, NC, USA., Krangel MS; Department of Immunology, Duke University Medical Center, Durham, NC, USA., Lenhard B; MRC London Institute of Medical Sciences, Institute of Clinical Sciences, Faculty of Medicine, Imperial College London, London, UK., Heyn H; CNAG-CRG, Centre for Genomic Regulation (CRG), The Barcelona Institute of Science and Technology (BIST), Barcelona, Spain., Fisher AG; MRC London Institute of Medical Sciences, Institute of Clinical Sciences, Faculty of Medicine, Imperial College London, London, UK., Štěpánek O; Laboratory of Adaptive Immunity, Institute of Molecular Genetics of the Czech Academy of Sciences, Prague, Czech Republic., Merkenschlager M; MRC London Institute of Medical Sciences, Institute of Clinical Sciences, Faculty of Medicine, Imperial College London, London, UK. matthias.merkenschlager@lms.mrc.ac.uk.

المصدر: Nature communications [Nat Commun] 2021 Jan 04; Vol. 12 (1), pp. 99. Date of Electronic Publication: 2021 Jan 04.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE

مواضيع طبية MeSH: CD4-Positive T-Lymphocytes/*cytology , CD8-Positive T-Lymphocytes/*cytology , Cell Differentiation/*immunology , Cell Lineage/*immunology , Thymus Gland/*cytology , Thymus Gland/*immunology, Animals ; CD4-Positive T-Lymphocytes/immunology ; CD8-Positive T-Lymphocytes/immunology ; Core Binding Factor Alpha 3 Subunit/metabolism ; Cytokines/metabolism ; DNA-Binding Proteins/metabolism ; Gene Expression Regulation ; Histocompatibility Antigens/metabolism ; Lymphocyte Activation/genetics ; Mice, Inbred C57BL ; Principal Component Analysis ; RNA, Messenger/genetics ; RNA, Messenger/metabolism ; Receptors, Antigen, T-Cell/metabolism ; Signal Transduction ; Transcription Factors/metabolism ; Mice