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1دورية أكاديمية
المؤلفون: Fernando Cavalcanti, Elena Gonzalez-Rey, Mario Delgado, Clara P. Falo, Leyre Mestre, Carmen Guaza, Francisco O’Valle, Michele M. P. Lufino, Jordi Xaus, Cristina Mascaró, Serena Lunardi, Natalia Sacilotto, Paola Dessanti, David Rotllant, Xavier Navarro, Mireia Herrando-Grabulosa, Carlos Buesa, Tamara Maes
المصدر: Pharmaceutics, Vol 14, Iss 7, p 1420 (2022)
مصطلحات موضوعية: epigenetics, KDM1A, vafidemstat, multiple sclerosis, neuroinflammation, Pharmacy and materia medica, RS1-441
وصف الملف: electronic resource
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2
المؤلفون: Alberto Ortega, Tamara Maes, Alejandra Rodríguez-Gimeno, Natalia Sacilotto, Michele Matteo Pio Lufino, Cristina Mascaró, Robert Soliva, Carlos Buesa, Paola Dessanti, Jordi Salas
المصدر: ACS Pharmacology & Translational Science. 4:1818-1834
مصطلحات موضوعية: Pharmacology, Class (set theory), Chemistry, Pharmacology (medical), Computational biology, Characterization (mathematics), Small molecule, In vitro
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3
المؤلفون: Dante Rotili, Paola Vianello, Annalisa Romanelli, Stefania Vultaggio, Davide Corinti, Mario Varasi, Oronza A. Botrugno, Claudia Binda, Nicola Mautone, Sergio Valente, Anna Cappa, Antonello Mai, Clemens Zwergel, Elisabetta Di Bello, Paola Dessanti, Andrea Mattevi, Saverio Minucci, Rossella Fioravanti, Annarita Rovere, Ciro Mercurio
المصدر: ChemMedChem
مصطلحات موضوعية: antiproliferative activity, Stereochemistry, Lysine, Antineoplastic Agents, 01 natural sciences, Biochemistry, Article, Structure-Activity Relationship, chemistry.chemical_compound, drug discovery, histone demethylases, lysine specific demethylase 1, structure-activity relationships, Cell Line, Tumor, Drug Discovery, medicine, Humans, Enzyme Inhibitors, General Pharmacology, Toxicology and Pharmaceutics, Benzamide, Cell Proliferation, Histone Demethylases, Pharmacology, Dose-Response Relationship, Drug, biology, 010405 organic chemistry, Drug discovery, Cell growth, Organic Chemistry, Tranylcypromine, 0104 chemical sciences, 010404 medicinal & biomolecular chemistry, chemistry, Cell culture, Microsomes, Liver, biology.protein, Molecular Medicine, Demethylase, Growth inhibition, medicine.drug
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4
المؤلفون: Natalia, Sacilotto, Paola, Dessanti, Michele M P, Lufino, Alberto, Ortega, Alejandra, Rodríguez-Gimeno, Jordi, Salas, Tamara, Maes, Carlos, Buesa, Cristina, Mascaró, Robert, Soliva
المصدر: ACS pharmacologytranslational science. 4(6)
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5
المؤلفون: Michele M.P. Lufino, Serena Lunardi, Natalia Sacilotto, Tamara Maes, Mireia Herrando-Grabulosa, David Rotllant, Carlos Buesa, Jordi Xaus, Paola Dessanti, Carmen Guaza, Xavier Navarro, Elena Gonzalez-Rey, Cristina Mascaró, Mario Delgado, F. L. Cavalcanti, Leyre Mestre
مصطلحات موضوعية: RCOR1, business.industry, Multiple sclerosis, Experimental autoimmune encephalomyelitis, medicine, KDM1A, Genomics, Epigenetics, Computational biology, medicine.disease, business
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::afc502a6fe4bd89e62039ecf96871e3e
https://doi.org/10.21203/rs.3.rs-114482/v4 -
6
المؤلفون: Andrea Mattevi, Loris Moretti, Saverio Minucci, Elena Legnaghi, Mario Varasi, Giuseppe Ciossani, Paola Dessanti, Oronza A. Botrugno, Alessia Romussi, Valentina Cecatiello, Elisa Zagarri, Raimondo Fattori, Paola Vianello, Manuela Villa, Florian Thaler, Giovanni Fagà, Giuseppe Meroni, Paolo Trifiro, Anna Cappa, Luca Sartori, Ciro Mercurio, Sebastiano Pasqualato, Federica Amigoni, Stefania Vultaggio
المصدر: Journal of Medicinal Chemistry. 60:1693-1715
مصطلحات موضوعية: 0301 basic medicine, Histone H3 Lysine 4, Stereochemistry, Lysine, Crystallography, X-Ray, 01 natural sciences, Inhibitory Concentration 50, Structure-Activity Relationship, 03 medical and health sciences, Cell Line, Tumor, Drug Discovery, Fluorescence Resonance Energy Transfer, Humans, Structure–activity relationship, Pyrroles, Enzyme Inhibitors, Histone Demethylases, biology, 010405 organic chemistry, Chemistry, KDM1A, Methylation, Ligand (biochemistry), High-Throughput Screening Assays, 0104 chemical sciences, 3. Good health, 030104 developmental biology, Histone, Biochemistry, Drug Design, biology.protein, Molecular Medicine, Demethylase
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7
المؤلفون: Roberto Dal Zuffo, Manuela Villa, Biagina Marrocco, Sergio Valente, Paolo Trifiro, Giuseppe Meroni, Mario Varasi, Oronza A. Botrugno, Anna Cappa, Paola Dessanti, Andrea Mattevi, Ciro Mercurio, Giulia Stazi, Saverio Minucci, Paola Vianello, Florian Thaler, Antonello Mai
المصدر: Journal of Medicinal Chemistry. 59:1501-1517
مصطلحات موضوعية: LSD1 epigenetics, monoamine-oxidase-b, breast-cancer, cyclopropylamine derivatives, modifying enzymes, LSD1 inhibition, methylation, cells, proteins, complex, targets, 0301 basic medicine, Acute promyelocytic leukemia, Administration, Oral, Antineoplastic Agents, Pharmacology, Structure-Activity Relationship, 03 medical and health sciences, 0302 clinical medicine, Leukemia, Promyelocytic, Acute, In vivo, Cell Line, Tumor, Drug Discovery, medicine, Humans, Structure–activity relationship, Enzyme Inhibitors, Clonogenic assay, Histone Demethylases, Acute leukemia, Chemistry, KDM1A, Biological activity, medicine.disease, Leukemia, 030104 developmental biology, 030220 oncology & carcinogenesis, Molecular Medicine, Tranylcypromine
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8
المؤلفون: Giannamaria Annunziato, Manuela Villa, Claudia Beato, Gabriele Costantino, Marco Pieroni, Elisa Azzali, Mario Varasi, Paolo Trifiro, Paola Vianello, Paola Dessanti, Ciro Mercurio, Giuseppe Meroni
المصدر: European Journal of Medicinal Chemistry. 92:377-386
مصطلحات موضوعية: Cyclopropanes, Models, Molecular, Stereochemistry, Structure-Activity Relationship, Drug Discovery, Histone methylation, medicine, Humans, Epigenetics, Histone Demethylases, Pharmacology, Dose-Response Relationship, Drug, Molecular Structure, biology, Chemistry, Organic Chemistry, Tranylcypromine, KDM1A, General Medicine, Recombinant Proteins, Histone, Biochemistry, Acetylation, DNA methylation, biology.protein, Demethylase, medicine.drug
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9
المؤلفون: Stefano Rovida, Giulia Stazi, Paola Dessanti, Veronica Rodriguez, Mario Varasi, Oronza A. Botrugno, Dante Rotili, Antonello Mai, Ciro Mercurio, Andrea Mattevi, Saverio Minucci, Giuseppe Ciossani, Sergio Valente, Alessia Lucidi, Paola Vianello
المصدر: MedChemComm. 6:665-670
مصطلحات موضوعية: animal structures, Stereochemistry, tranylcypromine, Pharmaceutical Science, Biochemistry, Residue (chemistry), chemistry.chemical_compound, lysine-specific demethylase 1, Drug Discovery, medicine, stereoisomers, Moiety, Pyrrole, Pharmacology, Indole test, epigenetics, Cell growth, Chemistry, Organic Chemistry, Tranylcypromine, leukemia, Cell culture, Cancer cell, Molecular Medicine, medicine.drug
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ca844cf9df35f84de1a28b52aa0b200
https://doi.org/10.1039/c4md00507d -
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المؤلفون: Andrea Mattevi, Marcello Tortorici, Paolo Trifiro, Giuseppe Meroni, Mario Varasi, Paola Dessanti, Oronza A. Botrugno, Florian Thaler, Manuela Villa, Giuseppe Ciossani, Sergio Valente, Paola Vianello, Anna Cappa, Antonello Mai, Ciro Mercurio, Saverio Minucci
المصدر: European Journal of Medicinal Chemistry. 86:352-363
مصطلحات موضوعية: Cyclopropanes, Models, Molecular, Stereochemistry, Crystallography, X-Ray, Structure-Activity Relationship, Drug Discovery, medicine, Humans, Moiety, Enzyme Inhibitors, Monoamine Oxidase, Histone Demethylases, Pharmacology, Dose-Response Relationship, Drug, Molecular Structure, biology, Chemistry, Organic Chemistry, Tranylcypromine, Biological activity, KDM1A, General Medicine, Histone, Biochemistry, biology.protein, Demethylase, Monoamine oxidase B, Monoamine oxidase A, medicine.drug