-
1
المؤلفون: Jennifer M. Atkinson, Megan Yates, Daniel D. Brown, Jagmohan Hooda, Rohit Bhargava, Paolo Schiavini, Marianna Zipeto, Steffi Oesterreich, ADRIAN V. LEE
المصدر: Cancer Research. 83:P3-08
مصطلحات موضوعية: Cancer Research, Oncology
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::c66fb4264506db44c01ce34ed7616bd0
https://doi.org/10.1158/1538-7445.sabcs22-p3-08-10 -
2
المؤلفون: Gilad Silberberg, Clare Killick-Cole, Yaron Mosesson, Haia Khoury, Xuan Ren, Mara Gilardi, Daniel Ciznadija, Paolo Schiavini, Marianna Zipeto, Michael Ritchie
المصدر: Cancer Research. 83:854-854
مصطلحات موضوعية: Cancer Research, Oncology
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::b90ad1dea12b27953a52b11e215b2393
https://doi.org/10.1158/1538-7445.am2023-854 -
3
المؤلفون: Elana Raaphorst, Donald F. Weaver, Darapaneni Chandra Mohan, Alexander Kreft, Paolo Schiavini, Jagadeesh P. Pasangulapati, Ramana Reddy Mittapalli, Fan Wu, Laura Villar, Eric C. Keske, Kurt R. Stover, Paul M. Stafford, Kiersten Thomas, Shea L. Johnson, Mark A. Reed, Siva R. Alla, Irina Sagamanova, Mayuri Gupta, Yong Zheng, Simmi Sharma
المصدر: ChemMedChem. 16:2195-2205
مصطلحات موضوعية: Models, Molecular, medicine.medical_treatment, Pharmacology, Blood–brain barrier, 01 natural sciences, Biochemistry, Structure-Activity Relationship, chemistry.chemical_compound, Docking (dog), Cancer immunotherapy, Drug Discovery, medicine, Humans, Indoleamine-Pyrrole 2,3,-Dioxygenase, Structure–activity relationship, Enzyme Inhibitors, General Pharmacology, Toxicology and Pharmaceutics, Indoleamine 2,3-dioxygenase, IC50, Indole test, Dose-Response Relationship, Drug, Molecular Structure, 010405 organic chemistry, Organic Chemistry, 0104 chemical sciences, 010404 medicinal & biomolecular chemistry, medicine.anatomical_structure, chemistry, Molecular Medicine, Penetrant (biochemical)
-
4
المؤلفون: Paolo Schiavini, André D.J. McKenzie, Michael Kassiou, Shane M. Wilkinson, Eryn L. Werry, Erick C.N. Wong, James O'Brien-Brown, Alexander Jackson, Alexandra Maximova
المصدر: European journal of pharmacology. 914
مصطلحات موضوعية: Pharmacology, Allosteric modulator, Purinergic P2X Receptor Antagonists, Chemistry, Activator (genetics), THP-1 Cells, Adamantane, Allosteric regulation, Antagonist, Porins, Receptor Activity-Modifying Proteins, chemistry.chemical_compound, Adenosine Triphosphate, HEK293 Cells, Drug Development, In vivo, Purinergic Agonists, Cathelicidins, Neuroinflammatory Diseases, Humans, Receptors, Purinergic P2X7, Guanidine, Receptor, Antimicrobial Cationic Peptides
-
5
المؤلفون: Donald F. Weaver, Paolo Schiavini, Michael G. Brant, Fan Wu, Paul M. Stafford, Autumn Meek, Jake Goodwin-tindall, Stephanie Wohnig, Kurt R. Stover
المصدر: ACS Medicinal Chemistry Letters. 9:131-136
مصطلحات موضوعية: 0301 basic medicine, chemistry.chemical_classification, Scaffold, Molecular model, Stereochemistry, Chemistry, Organic Chemistry, Imine, Arthritis, medicine.disease, Biochemistry, Chemical synthesis, 03 medical and health sciences, chemistry.chemical_compound, 030104 developmental biology, 0302 clinical medicine, Enzyme, 030220 oncology & carcinogenesis, Drug Discovery, medicine, Imidazole, Indoleamine 2,3-dioxygenase
-
6
المؤلفون: Donald F. Weaver, Alexander Kreft, Elana Raaphorst, Darapaneni Chandra Mohan, Yong Zheng, Paolo Schiavini, Paul M. Stafford, Jagadeesh P. Pasangulapati, Kurt R. Stover, Kiersten Thomas, Irina Sagamanova, Laura Villar, Mark A. Reed, Simmi Sharma, Ramana Reddy Mittapalli, Siva R. Alla, Eric C. Keske, Mayuri Gupta, Fan Wu, Shea L. Johnson
المصدر: ChemMedChem. 16:2157-2157
مصطلحات موضوعية: Pharmacology, chemistry.chemical_compound, Front cover, Chemistry, Stereochemistry, Organic Chemistry, Drug Discovery, Molecular Medicine, Imidazole, Structure–activity relationship, General Pharmacology, Toxicology and Pharmaceutics, Indoleamine 2,3-dioxygenase, Biochemistry
-
7
المؤلفون: Anthony Mittermaier, Igor Huskić, Stéphane De Cesco, Karine Auclair, Francesco Airaghi, Sylvain Rocheleau, Jerry Kurian, Nicolas Moitessier, Gaëlle Mariaule, Paolo Schiavini
المصدر: Journal of Medicinal Chemistry. 59:4221-4234
مصطلحات موضوعية: 0301 basic medicine, Stereochemistry, Carboxylic acid, Carboxylic Acids, Oligopeptidase, Stereoisomerism, Isoindoles, 01 natural sciences, Molecular Docking Simulation, Bridged Bicyclo Compounds, 03 medical and health sciences, chemistry.chemical_compound, Drug Discovery, Humans, Protease Inhibitors, chemistry.chemical_classification, Molecular Structure, Bicyclic molecule, 010405 organic chemistry, Chemistry, Serine Endopeptidases, Combinatorial chemistry, 0104 chemical sciences, 3. Good health, 030104 developmental biology, Docking (molecular), Covalent bond, Molecular Medicine, Prolyl Oligopeptidases, Isoindole
-
8
المؤلفون: Joshua Pottel, Karine Auclair, Nicolas Moitessier, Paolo Schiavini
المصدر: ChemMedChem. 10:1174-1183
مصطلحات موضوعية: Stereochemistry, Chemistry, Pharmaceutical, Oligopeptidase, Context (language use), Biochemistry, Article, Stereocenter, Drug Discovery, Humans, Enzyme Inhibitors, General Pharmacology, Toxicology and Pharmaceutics, Pharmacology, Molecular Structure, Chemistry, Serine Endopeptidases, Organic Chemistry, Primary metabolite, Nuclear magnetic resonance spectroscopy, Drug development, Microsomes, Liver, Thiazolidines, Molecular Medicine, Hydrogen–deuterium exchange, Epimer, Prolyl Oligopeptidases
-
9
المؤلفون: James, O'Brien-Brown, Alexander, Jackson, Tristan A, Reekie, Melissa L, Barron, Eryn L, Werry, Paolo, Schiavini, Michelle, McDonnell, Lenka, Munoz, Shane, Wilkinson, Benjamin, Noll, Shudong, Wang, Michael, Kassiou
المصدر: European journal of medicinal chemistry. 130
مصطلحات موضوعية: Behavior, Mice, Structure-Activity Relationship, Purinergic P2X Receptor Antagonists, Drug Discovery, Animals, Adamantane, Guanidines, Antidepressive Agents
-
10
المؤلفون: Paolo Schiavini, Michael Kassiou, Shane M. Wilkinson, James O'Brien-Brown, Shudong Wang, Alexander Jackson, Tristan A. Reekie, Michelle McDonnell, Benjamin Noll, Eryn L. Werry, Lenka Munoz, Melissa L. Barron
المساهمون: O'Brien-Brown, James, Jackson, Alexander, Reekie, Tristan A, Barron, Melissa L, Werry, Eryn L, Schiavini, Paolo, McDonnell, Michelle, Munoz, Lenka, Wilkinson, Shane, Noll, Benjamin, Wang, Shudong, Kassiou, Michael
مصطلحات موضوعية: 0301 basic medicine, Stereochemistry, Adamantane, adamantane, Neurodegenerative, Pharmacology, P2X7R antagonist, 03 medical and health sciences, chemistry.chemical_compound, Adamantyl, 0302 clinical medicine, Behavioral study, Amide, Drug Discovery, IL-1ß, P2x7 receptor, Inflammation, alzheimer's, Chemistry, Organic Chemistry, P2X(7)R antagonist, General Medicine, Alzheimer's, ATP, Inhibitory potency, 030104 developmental biology, P2X receptor, IL-1β, inflammation, neurodegenerative, adamantyl, Lead compound, 030217 neurology & neurosurgery
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::681397cd578e4e0f228fc10e6009debc
https://hdl.handle.net/11541.2/125305