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المؤلفون: Sheenagh G. Aiken, Joseph M. Bateman, Hsuan-Hung Liao, Alexander Fawcett, Teerawut Bootwicha, Paolo Vincetti, Eddie L. Myers, Adam Noble, Varinder K. Aggarwal
المصدر: Nature Chemistry. 15:248-256
مصطلحات موضوعية: General Chemical Engineering, General Chemistry
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المؤلفون: Peng Gao, Paolo Vincetti, Fabio Maria Sabbatini, Holly J. Carlisle, Luisa Mengatto, Stéphane De Lombaert, Anna Sava, Kerry Zobel, Xinying Liu, Claudia Beato, Jessica M. Bright, Alyssa M. A. Toda, Elena Serra, Federica Budassi, Marco Migliore, Laura Caberlotto, Cristiana Griffante, Silvia Bernardi, Mingliang Zhang, Albert W. Garofalo, Daniele Andreotti
المصدر: Journal of Medicinal Chemistry. 63:14821-14839
مصطلحات موضوعية: Indazoles, Tetrazoles, Leucine-Rich Repeat Serine-Threonine Protein Kinase-2, 01 natural sciences, Small Molecule Libraries, Mice, Structure-Activity Relationship, 03 medical and health sciences, Drug Discovery, Animals, Humans, Kinase activity, Protein Kinase Inhibitors, Gene, 030304 developmental biology, 0303 health sciences, Molecular Structure, Chemistry, Kinase, Highly selective, LRRK2, High-Throughput Screening Assays, nervous system diseases, 0104 chemical sciences, 010404 medicinal & biomolecular chemistry, HEK293 Cells, Pyrimidines, Mutation, Cancer research, Molecular Medicine
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المؤلفون: Sheenagh Aiken, Joe Bateman, Hsuan-Hung Liao, Alex Fawcett, Teerawut Bootwicha, Paolo Vincetti, Eddie Myers, Adam Noble, Varinder Aggarwal
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::63a6927e36a8e88a0013ed760809512d
https://doi.org/10.26434/chemrxiv-2022-g2h9s -
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المؤلفون: Sheenagh G, Aiken, Joseph M, Bateman, Hsuan-Hung, Liao, Alexander, Fawcett, Teerawut, Bootwicha, Paolo, Vincetti, Eddie L, Myers, Adam, Noble, Varinder K, Aggarwal
المصدر: Nature chemistry.
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المؤلفون: Gabriele Costantino, Marco Radi, Maria Grazia Martina, Paolo Vincetti
المصدر: Synlett. 30:2010-2014
مصطلحات موضوعية: Reaction conditions, Scaffold, Pyrimidine, 010405 organic chemistry, Chemistry, Organic Chemistry, 010402 general chemistry, 01 natural sciences, Combinatorial chemistry, 0104 chemical sciences, chemistry.chemical_compound, Nucleophile, Reactivity (chemistry), Amine gas treating
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::db863b6076c7e99b0e49f638c7882131
https://doi.org/10.1055/s-0039-1690205 -
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المصدر: ACS Medicinal Chemistry Letters. 10:558-563
مصطلحات موضوعية: Scaffold, 010405 organic chemistry, viruses, Phenotypic screening, Organic Chemistry, Allosteric regulation, Computational biology, Biology, medicine.disease, 01 natural sciences, Biochemistry, Chemical space, 0104 chemical sciences, Dengue fever, 010404 medicinal & biomolecular chemistry, Broad spectrum, Drug Discovery, medicine, biology.protein, Purine derivative, Polymerase
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المؤلفون: Paolo Vincetti, Suzanne J.F. Kaptein, Emmanuele Crespan, Jorge I. Armijos Rivera, Johan Neyts, Marco Radi, Gabriele Costantino, Giovanni Maga
المصدر: ChemMedChem. 13:1371-1376
مصطلحات موضوعية: Models, Molecular, 0301 basic medicine, Serotype, zika, viruses, Chemistry, Medicinal, Dengue virus, Virus Replication, medicine.disease_cause, Biochemistry, Dengue fever, Zika virus, Dengue, Broad spectrum, 0302 clinical medicine, INFECTION, Drug Discovery, CRYSTAL-STRUCTURE, Pharmacology & Pharmacy, General Pharmacology, Toxicology and Pharmaceutics, 2-Aminopurine, biology, Coinfection, Zika Virus Infection, ANTIVIRALS, virus diseases, DISEASES, 030220 oncology & carcinogenesis, Quinolines, broad-spectrum antivirals, Molecular Medicine, Life Sciences & Biomedicine, Antiviral Agents, 03 medical and health sciences, ANALOG, medicine, Humans, AGENTS, Pharmacology, Science & Technology, co-infections, KINASE INHIBITORS, Organic Chemistry, Outbreak, Zika Virus, Dengue Virus, biochemical phenomena, metabolism, and nutrition, medicine.disease, biology.organism_classification, dengue, Virology, 030104 developmental biology, Drug Design, 2,6-diaminopurines, DISCOVERY, Co infection
وصف الملف: Print-Electronic
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المؤلفون: Marco Radi, Alessandra Nigro, Elena Spina, Gabriele Costantino, Gabriele Carullo, Sabrina Tassini, Francescsa Aiello, Francesca Giordano, Antonio Garofalo, Agostino Bruno, Paolo Vincetti
المصدر: ChemMedChem. 12(16)
مصطلحات موضوعية: 0301 basic medicine, Cyclin-Dependent Kinase Inhibitor p21, medicine.drug_class, Cell Survival, Estrogen receptor, Antineoplastic Agents, Breast Neoplasms, Biology, Pharmacology, Biochemistry, Receptors, G-Protein-Coupled, 03 medical and health sciences, Breast cancer, Breast cancer cell line, Cell Line, Tumor, Quinoxalines, Drug Discovery, medicine, Estrogen Receptor beta, Humans, Cyclin D1, General Pharmacology, Toxicology and Pharmaceutics, Cell Proliferation, Virtual screening, Binding Sites, Organic Chemistry, Estrogen Receptor alpha, medicine.disease, Protein Structure, Tertiary, Molecular Docking Simulation, 030104 developmental biology, HEK293 Cells, Estrogen, Cancer research, MCF-7 Cells, Molecular Medicine, Female, Signal transduction, Cancer cell lines, Tumor Suppressor Protein p53, GPER
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المصدر: Tetrahedron Letters. 54:6905-6908
مصطلحات موضوعية: Rapid identification, Chemistry, Present method, Organic Chemistry, Drug Discovery, Two step, Organic chemistry, Ring (chemistry), Biochemistry, Microwave assisted
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المؤلفون: Gabriele Costantino, Nicolo Scalacci, Anna Brianza, Daniele Castagnolo, Marco Radi, Paolo Vincetti
المصدر: ChemInform. 47
مصطلحات موضوعية: Rapid identification, chemistry.chemical_compound, Chemistry, Present method, General Medicine, Benzofuran, Combinatorial chemistry, Microwave assisted, Protocol (object-oriented programming)