المؤلفون: Chen J; From the Departments of Internal Medicine (J.C., A.P., C.L.P., C.V., J.C., S.W., S.M., L.G., K.L.B., R.M., P.K., Y.-J.G., S.P., C.S.K., D.M.M.) and Integrative Biology and Pharmacology (J.X., M.X.Z.), The University of Texas Health Science Center at Houston; Anatomy and Cell Biology, Strathcona Anatomy and Dentistry Building, 3640 Rue University, Montreal, Quebec, Canada; and Internal Medicine, Institute for Translational Sciences, and Sealy Center for Molecular Medicine, University of Texas Medical Branch, Galveston (A.R.B.)., Peters A; From the Departments of Internal Medicine (J.C., A.P., C.L.P., C.V., J.C., S.W., S.M., L.G., K.L.B., R.M., P.K., Y.-J.G., S.P., C.S.K., D.M.M.) and Integrative Biology and Pharmacology (J.X., M.X.Z.), The University of Texas Health Science Center at Houston; Anatomy and Cell Biology, Strathcona Anatomy and Dentistry Building, 3640 Rue University, Montreal, Quebec, Canada; and Internal Medicine, Institute for Translational Sciences, and Sealy Center for Molecular Medicine, University of Texas Medical Branch, Galveston (A.R.B.)., Papke CL; From the Departments of Internal Medicine (J.C., A.P., C.L.P., C.V., J.C., S.W., S.M., L.G., K.L.B., R.M., P.K., Y.-J.G., S.P., C.S.K., D.M.M.) and Integrative Biology and Pharmacology (J.X., M.X.Z.), The University of Texas Health Science Center at Houston; Anatomy and Cell Biology, Strathcona Anatomy and Dentistry Building, 3640 Rue University, Montreal, Quebec, Canada; and Internal Medicine, Institute for Translational Sciences, and Sealy Center for Molecular Medicine, University of Texas Medical Branch, Galveston (A.R.B.)., Villamizar C; From the Departments of Internal Medicine (J.C., A.P., C.L.P., C.V., J.C., S.W., S.M., L.G., K.L.B., R.M., P.K., Y.-J.G., S.P., C.S.K., D.M.M.) and Integrative Biology and Pharmacology (J.X., M.X.Z.), The University of Texas Health Science Center at Houston; Anatomy and Cell Biology, Strathcona Anatomy and Dentistry Building, 3640 Rue University, Montreal, Quebec, Canada; and Internal Medicine, Institute for Translational Sciences, and Sealy Center for Molecular Medicine, University of Texas Medical Branch, Galveston (A.R.B.)., Ringuette LJ; From the Departments of Internal Medicine (J.C., A.P., C.L.P., C.V., J.C., S.W., S.M., L.G., K.L.B., R.M., P.K., Y.-J.G., S.P., C.S.K., D.M.M.) and Integrative Biology and Pharmacology (J.X., M.X.Z.), The University of Texas Health Science Center at Houston; Anatomy and Cell Biology, Strathcona Anatomy and Dentistry Building, 3640 Rue University, Montreal, Quebec, Canada; and Internal Medicine, Institute for Translational Sciences, and Sealy Center for Molecular Medicine, University of Texas Medical Branch, Galveston (A.R.B.)., Cao J; From the Departments of Internal Medicine (J.C., A.P., C.L.P., C.V., J.C., S.W., S.M., L.G., K.L.B., R.M., P.K., Y.-J.G., S.P., C.S.K., D.M.M.) and Integrative Biology and Pharmacology (J.X., M.X.Z.), The University of Texas Health Science Center at Houston; Anatomy and Cell Biology, Strathcona Anatomy and Dentistry Building, 3640 Rue University, Montreal, Quebec, Canada; and Internal Medicine, Institute for Translational Sciences, and Sealy Center for Molecular Medicine, University of Texas Medical Branch, Galveston (A.R.B.)., Wang S; From the Departments of Internal Medicine (J.C., A.P., C.L.P., C.V., J.C., S.W., S.M., L.G., K.L.B., R.M., P.K., Y.-J.G., S.P., C.S.K., D.M.M.) and Integrative Biology and Pharmacology (J.X., M.X.Z.), The University of Texas Health Science Center at Houston; Anatomy and Cell Biology, Strathcona Anatomy and Dentistry Building, 3640 Rue University, Montreal, Quebec, Canada; and Internal Medicine, Institute for Translational Sciences, and Sealy Center for Molecular Medicine, University of Texas Medical Branch, Galveston (A.R.B.)., Ma S; From the Departments of Internal Medicine (J.C., A.P., C.L.P., C.V., J.C., S.W., S.M., L.G., K.L.B., R.M., P.K., Y.-J.G., S.P., C.S.K., D.M.M.) and Integrative Biology and Pharmacology (J.X., M.X.Z.), The University of Texas Health Science Center at Houston; Anatomy and Cell Biology, Strathcona Anatomy and Dentistry Building, 3640 Rue University, Montreal, Quebec, Canada; and Internal Medicine, Institute for Translational Sciences, and Sealy Center for Molecular Medicine, University of Texas Medical Branch, Galveston (A.R.B.)., Gong L; From the Departments of Internal Medicine (J.C., A.P., C.L.P., C.V., J.C., S.W., S.M., L.G., K.L.B., R.M., P.K., Y.-J.G., S.P., C.S.K., D.M.M.) and Integrative Biology and Pharmacology (J.X., M.X.Z.), The University of Texas Health Science Center at Houston; Anatomy and Cell Biology, Strathcona Anatomy and Dentistry Building, 3640 Rue University, Montreal, Quebec, Canada; and Internal Medicine, Institute for Translational Sciences, and Sealy Center for Molecular Medicine, University of Texas Medical Branch, Galveston (A.R.B.)., Byanova KL; From the Departments of Internal Medicine (J.C., A.P., C.L.P., C.V., J.C., S.W., S.M., L.G., K.L.B., R.M., P.K., Y.-J.G., S.P., C.S.K., D.M.M.) and Integrative Biology and Pharmacology (J.X., M.X.Z.), The University of Texas Health Science Center at Houston; Anatomy and Cell Biology, Strathcona Anatomy and Dentistry Building, 3640 Rue University, Montreal, Quebec, Canada; and Internal Medicine, Institute for Translational Sciences, and Sealy Center for Molecular Medicine, University of Texas Medical Branch, Galveston (A.R.B.)., Xiong J; From the Departments of Internal Medicine (J.C., A.P., C.L.P., C.V., J.C., S.W., S.M., L.G., K.L.B., R.M., P.K., Y.-J.G., S.P., C.S.K., D.M.M.) and Integrative Biology and Pharmacology (J.X., M.X.Z.), The University of Texas Health Science Center at Houston; Anatomy and Cell Biology, Strathcona Anatomy and Dentistry Building, 3640 Rue University, Montreal, Quebec, Canada; and Internal Medicine, Institute for Translational Sciences, and Sealy Center for Molecular Medicine, University of Texas Medical Branch, Galveston (A.R.B.)., Zhu MX; From the Departments of Internal Medicine (J.C., A.P., C.L.P., C.V., J.C., S.W., S.M., L.G., K.L.B., R.M., P.K., Y.-J.G., S.P., C.S.K., D.M.M.) and Integrative Biology and Pharmacology (J.X., M.X.Z.), The University of Texas Health Science Center at Houston; Anatomy and Cell Biology, Strathcona Anatomy and Dentistry Building, 3640 Rue University, Montreal, Quebec, Canada; and Internal Medicine, Institute for Translational Sciences, and Sealy Center for Molecular Medicine, University of Texas Medical Branch, Galveston (A.R.B.)., Madonna R; From the Departments of Internal Medicine (J.C., A.P., C.L.P., C.V., J.C., S.W., S.M., L.G., K.L.B., R.M., P.K., Y.-J.G., S.P., C.S.K., D.M.M.) and Integrative Biology and Pharmacology (J.X., M.X.Z.), The University of Texas Health Science Center at Houston; Anatomy and Cell Biology, Strathcona Anatomy and Dentistry Building, 3640 Rue University, Montreal, Quebec, Canada; and Internal Medicine, Institute for Translational Sciences, and Sealy Center for Molecular Medicine, University of Texas Medical Branch, Galveston (A.R.B.)., Kee P; From the Departments of Internal Medicine (J.C., A.P., C.L.P., C.V., J.C., S.W., S.M., L.G., K.L.B., R.M., P.K., Y.-J.G., S.P., C.S.K., D.M.M.) and Integrative Biology and Pharmacology (J.X., M.X.Z.), The University of Texas Health Science Center at Houston; Anatomy and Cell Biology, Strathcona Anatomy and Dentistry Building, 3640 Rue University, Montreal, Quebec, Canada; and Internal Medicine, Institute for Translational Sciences, and Sealy Center for Molecular Medicine, University of Texas Medical Branch, Galveston (A.R.B.)., Geng YJ; From the Departments of Internal Medicine (J.C., A.P., C.L.P., C.V., J.C., S.W., S.M., L.G., K.L.B., R.M., P.K., Y.-J.G., S.P., C.S.K., D.M.M.) and Integrative Biology and Pharmacology (J.X., M.X.Z.), The University of Texas Health Science Center at Houston; Anatomy and Cell Biology, Strathcona Anatomy and Dentistry Building, 3640 Rue University, Montreal, Quebec, Canada; and Internal Medicine, Institute for Translational Sciences, and Sealy Center for Molecular Medicine, University of Texas Medical Branch, Galveston (A.R.B.)., Brasier AR; From the Departments of Internal Medicine (J.C., A.P., C.L.P., C.V., J.C., S.W., S.M., L.G., K.L.B., R.M., P.K., Y.-J.G., S.P., C.S.K., D.M.M.) and Integrative Biology and Pharmacology (J.X., M.X.Z.), The University of Texas Health Science Center at Houston; Anatomy and Cell Biology, Strathcona Anatomy and Dentistry Building, 3640 Rue University, Montreal, Quebec, Canada; and Internal Medicine, Institute for Translational Sciences, and Sealy Center for Molecular Medicine, University of Texas Medical Branch, Galveston (A.R.B.)., Davis EC; From the Departments of Internal Medicine (J.C., A.P., C.L.P., C.V., J.C., S.W., S.M., L.G., K.L.B., R.M., P.K., Y.-J.G., S.P., C.S.K., D.M.M.) and Integrative Biology and Pharmacology (J.X., M.X.Z.), The University of Texas Health Science Center at Houston; Anatomy and Cell Biology, Strathcona Anatomy and Dentistry Building, 3640 Rue University, Montreal, Quebec, Canada; and Internal Medicine, Institute for Translational Sciences, and Sealy Center for Molecular Medicine, University of Texas Medical Branch, Galveston (A.R.B.)., Prakash S; From the Departments of Internal Medicine (J.C., A.P., C.L.P., C.V., J.C., S.W., S.M., L.G., K.L.B., R.M., P.K., Y.-J.G., S.P., C.S.K., D.M.M.) and Integrative Biology and Pharmacology (J.X., M.X.Z.), The University of Texas Health Science Center at Houston; Anatomy and Cell Biology, Strathcona Anatomy and Dentistry Building, 3640 Rue University, Montreal, Quebec, Canada; and Internal Medicine, Institute for Translational Sciences, and Sealy Center for Molecular Medicine, University of Texas Medical Branch, Galveston (A.R.B.)., Kwartler CS; From the Departments of Internal Medicine (J.C., A.P., C.L.P., C.V., J.C., S.W., S.M., L.G., K.L.B., R.M., P.K., Y.-J.G., S.P., C.S.K., D.M.M.) and Integrative Biology and Pharmacology (J.X., M.X.Z.), The University of Texas Health Science Center at Houston; Anatomy and Cell Biology, Strathcona Anatomy and Dentistry Building, 3640 Rue University, Montreal, Quebec, Canada; and Internal Medicine, Institute for Translational Sciences, and Sealy Center for Molecular Medicine, University of Texas Medical Branch, Galveston (A.R.B.)., Milewicz DM; From the Departments of Internal Medicine (J.C., A.P., C.L.P., C.V., J.C., S.W., S.M., L.G., K.L.B., R.M., P.K., Y.-J.G., S.P., C.S.K., D.M.M.) and Integrative Biology and Pharmacology (J.X., M.X.Z.), The University of Texas Health Science Center at Houston; Anatomy and Cell Biology, Strathcona Anatomy and Dentistry Building, 3640 Rue University, Montreal, Quebec, Canada; and Internal Medicine, Institute for Translational Sciences, and Sealy Center for Molecular Medicine, University of Texas Medical Branch, Galveston (A.R.B.). Dianna.M.Milewicz@uth.tmc.edu.

المصدر: Circulation research [Circ Res] 2017 Jun 09; Vol. 120 (12), pp. 1903-1915. Date of Electronic Publication: 2017 May 01.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Lippincott Williams & Wilkins Country of Publication: United States NLM ID: 0047103 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1524-4571 (Electronic) Linking ISSN: 00097330 NLM ISO Abbreviation: Circ Res Subsets: MEDLINE

مواضيع طبية MeSH: Actins/*deficiency , Angiotensin II/*metabolism , Aorta, Thoracic/*metabolism , Myocytes, Smooth Muscle/*metabolism , NF-kappa B/*metabolism , Receptor, Angiotensin, Type 1/*biosynthesis, Actins/drug effects ; Actins/genetics ; Angiotensin II Type 1 Receptor Blockers/pharmacology ; Animals ; Aorta, Thoracic/drug effects ; Aorta, Thoracic/pathology ; Cells, Cultured ; Mice ; Mice, 129 Strain ; Mice, Inbred C57BL ; Mice, Knockout ; Muscle, Smooth, Vascular/drug effects ; Muscle, Smooth, Vascular/metabolism ; Myocytes, Smooth Muscle/drug effects ; Random Allocation ; Reactive Oxygen Species/metabolism ; Receptor, Angiotensin, Type 1/genetics

المؤلفون: Yamashiro Y; Department of Molecular Biology, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA., Papke CL; Department of Molecular Biology, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA., Kim J; Department of Mechanical Engineering and Materials Science, Washington University, St. Louis, MO 63130, USA., Ringuette LJ; Department of Anatomy and Cell Biology, McGill University, Montreal, Quebec H3A 0C7, Canada., Zhang QJ; Department of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA., Liu ZP; Department of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA., Mirzaei H; Department of Biochemistry and Proteomics Core Unit, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA., Wagenseil JE; Department of Mechanical Engineering and Materials Science, Washington University, St. Louis, MO 63130, USA., Davis EC; Department of Anatomy and Cell Biology, McGill University, Montreal, Quebec H3A 0C7, Canada., Yanagisawa H; Department of Molecular Biology, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA. Life Science Center of Tsukuba Advanced Research Alliance, University of Tsukuba, Tsukuba 305-8577, Japan. hkyanagisawa@tara.tsukuba.ac.jp.

المصدر: Science signaling [Sci Signal] 2015 Oct 20; Vol. 8 (399), pp. ra105. Date of Electronic Publication: 2015 Oct 20.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 101465400 Publication Model: Electronic Cited Medium: Internet ISSN: 1937-9145 (Electronic) Linking ISSN: 19450877 NLM ISO Abbreviation: Sci Signal Subsets: MEDLINE

مواضيع طبية MeSH: Actin Depolymerizing Factors/*physiology , Aortic Aneurysm/*physiopathology, Animals ; Disease Progression ; Mice

المؤلفون: Papke CL; Department of Molecular Biology, The University of Texas Southwestern Medical Center, Dallas, TX 75390, USA., Tsunezumi J; Department of Molecular Biology, The University of Texas Southwestern Medical Center, Dallas, TX 75390, USA., Ringuette LJ; Department of Anatomy and Cell Biology, McGill University, Montreal, Quebec H3A 0C7, Canada., Nagaoka H; NC Oral Health Institute, University of North Carolina, Chapel Hill, NC 27599, USA and., Terajima M; NC Oral Health Institute, University of North Carolina, Chapel Hill, NC 27599, USA and., Yamashiro Y; Department of Molecular Biology, The University of Texas Southwestern Medical Center, Dallas, TX 75390, USA, Life Science Center, Tsukuba Advanced Research Alliance, University of Tsukuba, 1-1-1 Tennodai, Tsukuba, Ibaraki 305-8577, Japan., Urquhart G; Department of Molecular Biology, The University of Texas Southwestern Medical Center, Dallas, TX 75390, USA., Yamauchi M; NC Oral Health Institute, University of North Carolina, Chapel Hill, NC 27599, USA and., Davis EC; Department of Anatomy and Cell Biology, McGill University, Montreal, Quebec H3A 0C7, Canada., Yanagisawa H; Department of Molecular Biology, The University of Texas Southwestern Medical Center, Dallas, TX 75390, USA, Life Science Center, Tsukuba Advanced Research Alliance, University of Tsukuba, 1-1-1 Tennodai, Tsukuba, Ibaraki 305-8577, Japan hiromi.yanagisawa@utsouthwestern.edu.

المصدر: Human molecular genetics [Hum Mol Genet] 2015 Oct 15; Vol. 24 (20), pp. 5867-79. Date of Electronic Publication: 2015 Jul 28.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: IRL Press at Oxford University Press Country of Publication: England NLM ID: 9208958 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1460-2083 (Electronic) Linking ISSN: 09646906 NLM ISO Abbreviation: Hum Mol Genet Subsets: MEDLINE

مواضيع طبية MeSH: Aorta/*metabolism , Collagen/*biosynthesis , Extracellular Matrix/*metabolism , Extracellular Matrix Proteins/*genetics, Animals ; Collagen/metabolism ; Elastin/metabolism ; Gene Deletion ; Homozygote ; Mice ; Muscle, Smooth/metabolism ; Oxidation-Reduction ; Protein-Lysine 6-Oxidase/metabolism ; Proteomics

المؤلفون: Papke CL; From the Department of Molecular Biology, UT Southwestern Medical Center, Dallas, TX (C.L.P., H.Y.); and Life Science Center, Tsukuba Advanced Research Alliance, University of Tsukuba, Tsukuba, Ibaraki, Japan (Y.Y., H.Y.)., Yamashiro Y; From the Department of Molecular Biology, UT Southwestern Medical Center, Dallas, TX (C.L.P., H.Y.); and Life Science Center, Tsukuba Advanced Research Alliance, University of Tsukuba, Tsukuba, Ibaraki, Japan (Y.Y., H.Y.)., Yanagisawa H; From the Department of Molecular Biology, UT Southwestern Medical Center, Dallas, TX (C.L.P., H.Y.); and Life Science Center, Tsukuba Advanced Research Alliance, University of Tsukuba, Tsukuba, Ibaraki, Japan (Y.Y., H.Y.). hiromi.yanagisawa@utsouthwestern.edu.

المصدر: Circulation research [Circ Res] 2015 Jul 03; Vol. 117 (2), pp. 109-12.

نوع المنشور: Editorial; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Comment

بيانات الدورية: Publisher: Lippincott Williams & Wilkins Country of Publication: United States NLM ID: 0047103 Publication Model: Print Cited Medium: Internet ISSN: 1524-4571 (Electronic) Linking ISSN: 00097330 NLM ISO Abbreviation: Circ Res Subsets: MEDLINE

مواضيع طبية MeSH: Mutation, Missense*, Aortic Dissection/*genetics , Aortic Aneurysm, Thoracic/*genetics , Matrix Metalloproteinases, Membrane-Associated/*physiology, Animals ; Humans ; Male

المؤلفون: Papke CL; Department of Molecular Biology, UT Southwestern Medical Center, 5323 Harry Hines Blvd., Dallas, TX 75390-9148, USA., Yanagisawa H; Department of Molecular Biology, UT Southwestern Medical Center, 5323 Harry Hines Blvd., Dallas, TX 75390-9148, USA. Electronic address: hiromi.yanagisawa@utsouthwestern.edu.

المصدر: Matrix biology : journal of the International Society for Matrix Biology [Matrix Biol] 2014 Jul; Vol. 37, pp. 142-9. Date of Electronic Publication: 2014 Mar 06.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Review

بيانات الدورية: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 9432592 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1569-1802 (Electronic) Linking ISSN: 0945053X NLM ISO Abbreviation: Matrix Biol Subsets: MEDLINE

مواضيع طبية MeSH: Aorta/*embryology , Elastin/*biosynthesis , Elastin/*metabolism , Extracellular Matrix Proteins/*metabolism , Gene Expression Regulation, Enzymologic/*physiology , Signal Transduction/*physiology, Animals ; Aorta/metabolism ; Extracellular Matrix Proteins/genetics ; Gene Expression Regulation, Enzymologic/genetics ; Humans ; Integrins/metabolism ; Mice ; Mice, Knockout ; MicroRNAs/immunology ; Myocytes, Smooth Muscle/metabolism ; Peptide Hydrolases/metabolism

المؤلفون: Papke CL; Department of Internal Medicine, University of Texas Health Science Center at Houston, 6431 Fannin, MSB 6.100, Houston, TX 77030, USA., Cao J, Kwartler CS, Villamizar C, Byanova KL, Lim SM, Sreenivasappa H, Fischer G, Pham J, Rees M, Wang M, Chaponnier C, Gabbiani G, Khakoo AY, Chandra J, Trache A, Zimmer W, Milewicz DM

المصدر: Human molecular genetics [Hum Mol Genet] 2013 Aug 01; Vol. 22 (15), pp. 3123-37. Date of Electronic Publication: 2013 Apr 15.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: IRL Press at Oxford University Press Country of Publication: England NLM ID: 9208958 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1460-2083 (Electronic) Linking ISSN: 09646906 NLM ISO Abbreviation: Hum Mol Genet Subsets: MEDLINE

مواضيع طبية MeSH: Actins/*metabolism , Focal Adhesion Protein-Tyrosine Kinases/*metabolism , Myocytes, Smooth Muscle/*metabolism , Myocytes, Smooth Muscle/*pathology , Receptor, Platelet-Derived Growth Factor beta/*metabolism , Tumor Suppressor Protein p53/*metabolism, Actins/genetics ; Animals ; Cell Movement/genetics ; Cell Nucleus/metabolism ; Cell Proliferation ; Enzyme Activation ; Hyperplasia ; Mice ; Mice, Knockout ; Models, Biological ; Phenotype ; Protein Transport ; Reactive Oxygen Species/metabolism

المؤلفون: Huang J; Department of Molecular Biology, University of Texas Southwestern Medical Center, Dallas, TX 75390-9148., Yamashiro Y; Department of Molecular Biology, University of Texas Southwestern Medical Center, Dallas, TX 75390-9148., Papke CL; Department of Molecular Biology, University of Texas Southwestern Medical Center, Dallas, TX 75390-9148., Ikeda Y; Department of Molecular Genetics, University of Texas Southwestern Medical Center, Dallas, TX 75390-9148.; Howard Hughes Medical Institute, University of Texas Southwestern Medical Center, Dallas, TX 75390-9050., Lin Y; Department of Molecular Biology, University of Texas Southwestern Medical Center, Dallas, TX 75390-9148., Patel M; Department of Molecular Biology, University of Texas Southwestern Medical Center, Dallas, TX 75390-9148., Inagami T; Department of Biochemistry, School of Medicine, Vanderbilt University, Nashville, TN 37235., Le VP; Department of Biomedical Engineering, St. Louis University, St. Louis, MO 63103-2010., Wagenseil JE; Department of Biomedical Engineering, St. Louis University, St. Louis, MO 63103-2010., Yanagisawa H; Department of Molecular Biology, University of Texas Southwestern Medical Center, Dallas, TX 75390-9148.

المصدر: Science translational medicine [Sci Transl Med] 2013 May 01; Vol. 5 (183), pp. 183ra58, 1-11.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 101505086 Publication Model: Print Cited Medium: Internet ISSN: 1946-6242 (Electronic) Linking ISSN: 19466234 NLM ISO Abbreviation: Sci Transl Med Subsets: MEDLINE

مواضيع طبية MeSH: Signal Transduction*/drug effects, Angiotensin II/*metabolism , Aorta/*pathology , Aortic Aneurysm/*enzymology , Aortic Aneurysm/*pathology , Extracellular Matrix Proteins/*deficiency , Peptidyl-Dipeptidase A/*metabolism, Animals ; Aorta/enzymology ; Aortic Aneurysm/drug therapy ; Aortic Aneurysm/physiopathology ; Biomarkers/metabolism ; Biomechanical Phenomena/drug effects ; Blood Pressure/drug effects ; Captopril/pharmacology ; Captopril/therapeutic use ; Cell Differentiation/drug effects ; Extracellular Matrix Proteins/metabolism ; Extracellular Signal-Regulated MAP Kinases/metabolism ; Gene Deletion ; Losartan/pharmacology ; Losartan/therapeutic use ; Male ; Mice ; Mice, Knockout ; Muscle, Smooth, Vascular/pathology ; Myocytes, Smooth Muscle/drug effects ; Myocytes, Smooth Muscle/enzymology ; Myocytes, Smooth Muscle/pathology ; Phenotype ; Phosphorylation/drug effects ; Receptor, Angiotensin, Type 1/metabolism ; Receptor, Angiotensin, Type 2/metabolism ; Time Factors ; Up-Regulation/drug effects

المؤلفون: Milewicz DM; From the Division of Medical Genetics, Department of Internal Medicine, University of Texas Health Science Center at Houston, Houston, Texas, USA. Dianna.M.Milewicz@uth.tmc.edu, Kwartler CS, Papke CL, Regalado ES, Cao J, Reid AJ

المصدر: Genetics in medicine : official journal of the American College of Medical Genetics [Genet Med] 2010 Apr; Vol. 12 (4), pp. 196-203.

نوع المنشور: Case Reports; Journal Article; Review

بيانات الدورية: Publisher: Elsevier Country of Publication: United States NLM ID: 9815831 Publication Model: Print Cited Medium: Internet ISSN: 1530-0366 (Electronic) Linking ISSN: 10983600 NLM ISO Abbreviation: Genet Med Subsets: MEDLINE

مواضيع طبية MeSH: Cell Proliferation* , Mutation*, Myocytes, Smooth Muscle/*metabolism , Vascular Diseases/*genetics, Actins/genetics ; Adult ; Coronary Vessels/metabolism ; Coronary Vessels/pathology ; Humans ; Hyperplasia ; Myocytes, Smooth Muscle/pathology ; Neurofibromin 1/genetics ; Vascular Diseases/pathology

المؤلفون: Guo DC; The University of Texas Health Science Center at Houston, Houston, TX 77030, USA., Papke CL, Tran-Fadulu V, Regalado ES, Avidan N, Johnson RJ, Kim DH, Pannu H, Willing MC, Sparks E, Pyeritz RE, Singh MN, Dalman RL, Grotta JC, Marian AJ, Boerwinkle EA, Frazier LQ, LeMaire SA, Coselli JS, Estrera AL, Safi HJ, Veeraraghavan S, Muzny DM, Wheeler DA, Willerson JT, Yu RK, Shete SS, Scherer SE, Raman CS, Buja LM, Milewicz DM

المصدر: American journal of human genetics [Am J Hum Genet] 2009 May; Vol. 84 (5), pp. 617-27. Date of Electronic Publication: 2009 Apr 30.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Cell Press Country of Publication: United States NLM ID: 0370475 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1537-6605 (Electronic) Linking ISSN: 00029297 NLM ISO Abbreviation: Am J Hum Genet Subsets: MEDLINE

مواضيع طبية MeSH: Actins/*genetics , Aortic Dissection/*genetics , Aortic Aneurysm, Thoracic/*genetics , Coronary Artery Disease/*genetics , Moyamoya Disease/*genetics , Stroke/*genetics, Actins/metabolism ; Adolescent ; Adult ; Aortic Dissection/pathology ; Aortic Aneurysm, Thoracic/pathology ; Cell Proliferation ; Cells, Cultured ; Coronary Artery Disease/pathology ; Female ; Genetic Predisposition to Disease ; Humans ; Male ; Middle Aged ; Models, Molecular ; Moyamoya Disease/pathology ; Mutation ; Myocytes, Smooth Muscle/metabolism ; Protein Isoforms/genetics ; Protein Isoforms/metabolism ; Young Adult

المؤلفون: He R; Department of Internal Medicine, The University of Texas Medical School at Houston, Houston, Texas 77030, USA., Guo DC, Sun W, Papke CL, Duraisamy S, Estrera AL, Safi HJ, Ahn C, Buja LM, Arnett FC, Zhang J, Geng YJ, Milewicz DM

المصدر: The Journal of thoracic and cardiovascular surgery [J Thorac Cardiovasc Surg] 2008 Oct; Vol. 136 (4), pp. 922-9, 929.e1. Date of Electronic Publication: 2008 Jun 12.

نوع المنشور: Comparative Study; Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Mosby Country of Publication: United States NLM ID: 0376343 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1097-685X (Electronic) Linking ISSN: 00225223 NLM ISO Abbreviation: J Thorac Cardiovasc Surg Subsets: MEDLINE

مواضيع طبية MeSH: Aortic Aneurysm, Abdominal/*pathology , Aortic Aneurysm, Thoracic/*pathology , Marfan Syndrome/*pathology , Receptors, Antigen, T-Cell/*immunology , Transforming Growth Factor beta2/*immunology, Adult ; Aged ; Antigens, CD/immunology ; Antigens, CD/metabolism ; Antigens, Differentiation, T-Lymphocyte/genetics ; Antigens, Differentiation, T-Lymphocyte/metabolism ; Aortic Aneurysm, Abdominal/immunology ; Aortic Aneurysm, Abdominal/surgery ; Aortic Aneurysm, Thoracic/immunology ; Aortic Aneurysm, Thoracic/surgery ; Biomarkers/analysis ; Biopsy, Needle ; Cardiac Surgical Procedures/methods ; Case-Control Studies ; Female ; Humans ; Immunohistochemistry ; Male ; Marfan Syndrome/genetics ; Marfan Syndrome/surgery ; Middle Aged ; Multivariate Analysis ; RNA/analysis ; Receptors, Antigen, T-Cell/metabolism ; Reference Values ; Reverse Transcriptase Polymerase Chain Reaction ; Sensitivity and Specificity ; Statistics, Nonparametric ; Tissue Culture Techniques ; Transforming Growth Factor beta2/analysis ; Vascular Cell Adhesion Molecule-1/immunology ; Vascular Cell Adhesion Molecule-1/metabolism