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المؤلفون: Andrej Emanuel Cotman, Martina Durcik, Davide Benedetto Tiz, Federica Fulgheri, Daniela Secci, Maša Sterle, Štefan Možina, Žiga Skok, Nace Zidar, Anamarija Zega, Janez Ilaš, Lucija Peterlin Mašič, Tihomir Tomašič, Diarmaid Hughes, Douglas L. Huseby, Sha Cao, Linnéa Garoff, Talía Berruga Fernández, Paraskevi Giachou, Lisa Crone, Ivailo Simoff, Richard Svensson, Bryndis Birnir, Sergiy V. Korol, Zhe Jin, Francisca Vicente, Maria C. Ramos, Mercedes de la Cruz, Björn Glinghammar, Lena Lenhammar, Sara R. Henderson, Julia E. A. Mundy, Anthony Maxwell, Clare E. M. Stevenson, David M. Lawson, Guido V. Janssen, Geert Jan Sterk, Danijel Kikelj
المساهمون: Medicinal chemistry, AIMMS
المصدر: Journal of medicinal chemistry, vol. 66, no. 2, 2023.
Journal of medicinal chemistry, str. 1380-1425 : Ilustr., Vol. 66, no. 2, 2023
COBISS-ID: 512806681
Journal of medicinal chemistry, 66(2), 1380-1425. American Chemical Society
Cotman, A E, Durcik, M, Benedetto Tiz, D, Fulgheri, F, Secci, D, Sterle, M, Možina, Š, Skok, Ž, Zidar, N, Zega, A, Ilaš, J, Peterlin Mašič, L, Tomašič, T, Hughes, D, Huseby, D L, Cao, S, Garoff, L, Berruga Fernández, T, Giachou, P, Crone, L, Simoff, I, Svensson, R, Birnir, B, Korol, S V, Jin, Z, Vicente, F, Ramos, M C, De La Cruz, M, Glinghammar, B, Lenhammar, L, Henderson, S R, Mundy, J E A, Maxwell, A, Stevenson, C E M, Lawson, D M, Janssen, G V, Sterk, G J & Kikelj, D 2023, ' Discovery and Hit-to-Lead Optimization of Benzothiazole Scaffold-Based DNA Gyrase Inhibitors with Potent Activity against Acinetobacter baumannii and Pseudomonas aeruginosa ', Journal of medicinal chemistry, vol. 66, no. 2, pp. 1380-1425 . https://doi.org/10.1021/acs.jmedchem.2c01597مصطلحات موضوعية: antibacterial activity, bacteria, genetics, inhibitors, solubility, zaviralci, topnost, bakterijska rezistenca, solubility, Bakterijska rezistenca, Topnost, Läkemedelskemi, udc:615, bakterije, Bakterije, antibacterial activity, genetika, Drug Discovery, inhibitors, Molecular Medicine, antibakterijsko delovanje, zaviralci, genetics, antibakterijsko delovanje, Genetika, Medicinal Chemistry, bacteria, udc:615.015.8
وصف الملف: application/pdf; text/url
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المؤلفون: Sha Cao, Diarmaid Hughes, Carina Vingsbo Lundberg, Sven N. Hobbie, Solveiga Grinberga, Edgars Liepinsh, Anna Petersson, Malgorzata Urbas, Paraskevi Giachou, Tomás Sou, Dorota Zabicka, Maria Backlund, Jon Hansen, Lena E. Friberg, Magdalena Tomczak, Onur Ercan
المساهمون: University of Zurich, Friberg, Lena E
المصدر: Clinical Pharmacology and Therapeutics
مصطلحات موضوعية: Guinea Pigs, 610 Medicine & health, Pharmacology, Apramycin, 030226 pharmacology & pharmacy, Models, Biological, Article, 03 medical and health sciences, Pharmaceutical Sciences, Mice, 0302 clinical medicine, Dogs, Pharmacokinetics, In vivo, medicine, Escherichia coli, 2736 Pharmacology (medical), Animals, Nebramycin, Pharmacology (medical), PK/PD models, Volume of distribution, Bacteriological Techniques, Dose-Response Relationship, Drug, Chemistry, 10179 Institute of Medical Microbiology, Research, Aminoglycoside, Articles, Farmaceutiska vetenskaper, Anti-Bacterial Agents, Rats, 3004 Pharmacology, Drug development, 030220 oncology & carcinogenesis, Pharmacodynamics, Area Under Curve, 570 Life sciences, biology, medicine.drug
وصف الملف: application/pdf; cpt.2104.pdf - application/pdf
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