المؤلفون: Afzali AM; Institute for Experimental Neuroimmunology, Technical University of Munich School of Medicine and Health, Munich, Germany.; Department of Neurology, Technical University of Munich School of Medicine and Health, Munich, Germany.; Munich Cluster for Systems Neurology, Munich, Germany., Nirschl L; Institute for Experimental Neuroimmunology, Technical University of Munich School of Medicine and Health, Munich, Germany., Sie C; Institute for Experimental Neuroimmunology, Technical University of Munich School of Medicine and Health, Munich, Germany., Pfaller M; Institute for Experimental Neuroimmunology, Technical University of Munich School of Medicine and Health, Munich, Germany., Ulianov O; Institute for Experimental Neuroimmunology, Technical University of Munich School of Medicine and Health, Munich, Germany., Hassler T; Biomedical Center (BMC), Institute for Immunology, Faculty of Medicine, Ludwig-Maximilians-University Munich, Planegg-Martinsried, Germany., Federle C; Biomedical Center (BMC), Institute for Immunology, Faculty of Medicine, Ludwig-Maximilians-University Munich, Planegg-Martinsried, Germany., Petrozziello E; Biomedical Center (BMC), Institute for Immunology, Faculty of Medicine, Ludwig-Maximilians-University Munich, Planegg-Martinsried, Germany., Kalluri SR; Department of Neurology, Technical University of Munich School of Medicine and Health, Munich, Germany., Chen HH; Institute for Experimental Neuroimmunology, Technical University of Munich School of Medicine and Health, Munich, Germany., Tyystjärvi S; Institute for Experimental Neuroimmunology, Technical University of Munich School of Medicine and Health, Munich, Germany., Muschaweckh A; Institute for Experimental Neuroimmunology, Technical University of Munich School of Medicine and Health, Munich, Germany., Lammens K; Department of Biochemistry at the Gene Center, Ludwig-Maximilians-University, Munich, Germany., Delbridge C; Institute of Pathology, Technical University of Munich School of Medicine and Health, Munich, Germany.; Department of Neuropathology, Institute of Pathology, Technical University of Munich School of Medicine and Health, Munich, Germany., Büttner A; Institute of Forensic Medicine, Rostock University Medical Center, Rostock, Germany., Steiger K; Institute of Pathology, Technical University of Munich School of Medicine and Health, Munich, Germany., Seyhan G; Institute for Experimental Hematology, TranslaTUM Cancer Center, Technical University of Munich School of Medicine and Health, Munich, Germany., Ottersen OP; Division of Anatomy, Institute of Basic Medical Sciences, University of Oslo, Oslo, Norway., Öllinger R; Institute of Molecular Oncology and Functional Genomics, TranslaTUM Cancer Center, Technical University of Munich School of Medicine and Health, Munich, Germany., Rad R; Institute of Molecular Oncology and Functional Genomics, TranslaTUM Cancer Center, Technical University of Munich School of Medicine and Health, Munich, Germany., Jarosch S; Institute for Medical Microbiology, Immunology and Hygiene, Technical University of Munich School of Medicine and Health, Munich, Germany., Straub A; Institute for Medical Microbiology, Immunology and Hygiene, Technical University of Munich School of Medicine and Health, Munich, Germany., Mühlbauer A; Institute for Medical Microbiology, Immunology and Hygiene, Technical University of Munich School of Medicine and Health, Munich, Germany., Grassmann S; Immunology Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Hemmer B; Department of Neurology, Technical University of Munich School of Medicine and Health, Munich, Germany.; Munich Cluster for Systems Neurology, Munich, Germany., Böttcher JP; Institute of Molecular Immunology, Technical University of Munich School of Medicine and Health, Munich, Germany., Wagner I; Department of Pathology and Immunology, Division of Clinical Pathology, Geneva Faculty of Medicine, Centre Médical Universitaire, Geneva, Switzerland., Kreutzfeldt M; Department of Pathology and Immunology, Division of Clinical Pathology, Geneva Faculty of Medicine, Centre Médical Universitaire, Geneva, Switzerland., Merkler D; Department of Pathology and Immunology, Division of Clinical Pathology, Geneva Faculty of Medicine, Centre Médical Universitaire, Geneva, Switzerland., Pardàs IB; Institute for Computational Biology, Helmholtz Munich, Neuherberg, Germany., Schmidt Supprian M; Institute for Experimental Hematology, TranslaTUM Cancer Center, Technical University of Munich School of Medicine and Health, Munich, Germany., Buchholz VR; Institute for Medical Microbiology, Immunology and Hygiene, Technical University of Munich School of Medicine and Health, Munich, Germany., Heink S; Institute for Experimental Neuroimmunology, Technical University of Munich School of Medicine and Health, Munich, Germany., Busch DH; Institute for Medical Microbiology, Immunology and Hygiene, Technical University of Munich School of Medicine and Health, Munich, Germany.; German Center for Infection Research (DZIF), Partner Site Munich, Munich, Germany., Klein L; Biomedical Center (BMC), Institute for Immunology, Faculty of Medicine, Ludwig-Maximilians-University Munich, Planegg-Martinsried, Germany., Korn T; Institute for Experimental Neuroimmunology, Technical University of Munich School of Medicine and Health, Munich, Germany. thomas.korn@tum.de.; Department of Neurology, Technical University of Munich School of Medicine and Health, Munich, Germany. thomas.korn@tum.de.; Munich Cluster for Systems Neurology, Munich, Germany. thomas.korn@tum.de.

المصدر: Nature [Nature] 2024 Mar; Vol. 627 (8003), pp. 407-415. Date of Electronic Publication: 2024 Feb 21.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 0410462 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-4687 (Electronic) Linking ISSN: 00280836 NLM ISO Abbreviation: Nature Subsets: MEDLINE

مواضيع طبية MeSH: Aquaporin 4*/deficiency , Aquaporin 4*/genetics , Aquaporin 4*/immunology , Aquaporin 4*/metabolism , Autoantibodies*/immunology , Autoantigens*/immunology , B-Lymphocytes*/immunology , B-Lymphocytes*/metabolism , Immune Tolerance* , Neuromyelitis Optica*/immunology , Neuromyelitis Optica*/metabolism, Animals ; Humans ; Mice ; AIRE Protein ; CD40 Antigens/immunology ; Germinal Center/cytology ; Germinal Center/immunology ; Receptors, Antigen, T-Cell/immunology ; T-Lymphocytes/immunology ; Thymus Gland/cytology ; Thymus Gland/immunology ; Thyroid Epithelial Cells/immunology ; Thyroid Epithelial Cells/metabolism ; Transcriptome