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1دورية أكاديمية
المؤلفون: Pascal Krotee, Jose A Rodriguez, Michael R Sawaya, Duilio Cascio, Francis E Reyes, Dan Shi, Johan Hattne, Brent L Nannenga, Marie E Oskarsson, Stephan Philipp, Sarah Griner, Lin Jiang, Charles G Glabe, Gunilla T Westermark, Tamir Gonen, David S Eisenberg
المصدر: eLife, Vol 6 (2017)
مصطلحات موضوعية: islet amyloid polypeptide, amyloid fibril, cytotoxicity, MicroED, Type-II Diabetes, Medicine, Science, Biology (General), QH301-705.5
وصف الملف: electronic resource
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المؤلفون: Michael R. Sawaya, Pascal Krotee, Paul M. Seidler, Dan Shi, Charles G. Glabe, Sarah Griner, Lorena Saelices, David Eisenberg, Kevin A. Murray, Duilio Cascio, Ji Lee, Stephan Philipp, Tamir Gonen, Lin Jiang, Jose Rodriguez
المصدر: The Journal of biological chemistry, vol 293, iss 8
مصطلحات موضوعية: Models, Molecular, 0301 basic medicine, Aging, Molecular model, Amyloid β, Neurodegenerative, Crystallography, X-Ray, Alzheimer's Disease, Biochemistry, Medical and Health Sciences, Mice, 0302 clinical medicine, Models, Insulin-Secreting Cells, 2.1 Biological and endogenous factors, Aetiology, Cytotoxicity, Nootropic Agents, Neurons, Microscopy, geography.geographical_feature_category, Tumor, Crystallography, Chemistry, Diabetes, amyloid, Molecular Bases of Disease, Neurofibrillary Tangles, Biological Sciences, Islet, Recombinant Proteins, Islet Amyloid Polypeptide, inhibitor, Neurological, electron diffraction, crystal structure, Biochemistry & Molecular Biology, Amyloid, human islet amyloid polypeptide, Structural similarity, amyloid-β, Fibril, Protein Aggregation, Pathological, Electron, peptide interaction, Cell Line, 03 medical and health sciences, Microscopy, Electron, Transmission, Pathological, Cell Line, Tumor, Acquired Cognitive Impairment, Animals, Humans, Hypoglycemic Agents, Transmission, Molecular Biology, Metabolic and endocrine, geography, Amyloid beta-Peptides, Computational Biology, Molecular, Alzheimer's Disease including Alzheimer's Disease Related Dementias (AD/ADRD), Cell Biology, Protein Aggregation, Peptide Fragments, Rats, Brain Disorders, 030104 developmental biology, HEK293 Cells, Amino Acid Substitution, Drug Design, Mutation, Chemical Sciences, Biophysics, X-Ray, Structure based, Dementia, 030217 neurology & neurosurgery
وصف الملف: application/pdf
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc55315e7d7fe3dd55c6418227010826
https://escholarship.org/uc/item/6368r0x1 -
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المؤلفون: David Eisenberg, Pascal Krotee, Stephan Philipp, Michael R. Sawaya, Jose A. Rodriguez, Tamir Gonen, Marie E. Oskarsson, Gunilla T. Westermark, Duilio Cascio, Sarah Griner, Dan Shi, Charles G. Glabe, Brent L. Nannenga, Francis E. Reyes, Johan Hattne, Lin Jiang
المصدر: eLife
eLife, Vol 6 (2017)مصطلحات موضوعية: 0301 basic medicine, Protein Conformation, Cell- och molekylärbiologi, Biochemistry, Type ii diabetes, Insulin-Secreting Cells, biophysics, amyloid fibril, Cytotoxic T cell, structural biology, Biology (General), Cytotoxicity, Cells, Cultured, Cultured, Chemistry, General Neuroscience, General Medicine, Biophysics and Structural Biology, Islet Amyloid Polypeptide, Cell and molecular biology, Endokrinologi och diabetes, Medicine, cytotoxicity, MicroED, Research Article, Human, Programmed cell death, Amyloid, QH301-705.5, Cell Survival, Science, Cells, Endocrinology and Diabetes, Fibril, General Biochemistry, Genetics and Molecular Biology, 03 medical and health sciences, Type-II Diabetes, Humans, biochemistry, human, 030102 biochemistry & molecular biology, General Immunology and Microbiology, Cryoelectron Microscopy, 030104 developmental biology, Structural biology, Biophysics, Protein Conformation, beta-Strand, beta-Strand, Generic health relevance, Biochemistry and Cell Biology, Cell and Molecular Biology
وصف الملف: application/pdf
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fad9cbcca775396d40dce43913666132
http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-316042 -
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المؤلفون: Michael R. Sawaya, Lin Jiang, Stephan Philipp, Sarah Griner, Jose A. Rodriguez, David Eisenberg, Dan Shi, Gunilla T. Westermark, Pascal Krotee, Charles G. Glabe, Duilio Cascio, Marie E. Oskarsson, Tamir Gonen, Johan Hattne, Francis E. Reyes, Brent L. Nannenga
مصطلحات موضوعية: Chemistry, Biophysics, Cytotoxicity
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::2f2ff67c8a0d43506d6d2be6f7e6dc50
https://doi.org/10.7554/elife.19273.026 -
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المؤلفون: Thomas G. Graeber, Carolina Espindola Camacho, Siavash K. Kurdistani, Wen Gu, Brian Gardner, Iman Saramipoor Behbahan, Ingo K. Mellinghoff, Lee Goodglick, Steven M. Dubinett, David Chia, Nicholas A. Graham, Heather R. Christofk, Steve Horvath, Susan E. Critchlow, Mohammed Alavi, Lora Bagryanova, Sara A. Hurvitz, Pascal Krotee, Erin L. Maresh, Daniel Braas, Candice Sun Hong, Vei Mah
المصدر: Cell reports, vol 14, iss 7
Hong, CS; Graham, NA; Gu, W; Espindola Camacho, C; Mah, V; Maresh, EL; et al.(2016). MCT1 Modulates Cancer Cell Pyruvate Export and Growth of Tumors that Co-express MCT1 and MCT4. Cell Reports, 14(7), 1590-1601. doi: 10.1016/j.celrep.2016.01.057. UCLA: Retrieved from: http://www.escholarship.org/uc/item/92p5w832مصطلحات موضوعية: 0301 basic medicine, Lactate transport, Lung Neoplasms, Medical Physiology, Muscle Proteins, Oxidative Phosphorylation, chemistry.chemical_compound, Mice, Pyruvic Acid, 2.1 Biological and endogenous factors, Glycolysis, Aetiology, Cancer, Tumor, Symporters, 3. Good health, Tumor Burden, Gene Expression Regulation, Neoplastic, Monocarboxylate transporter 1, Female, Signal transduction, Signal Transduction, Monocarboxylic Acid Transporters, medicine.medical_specialty, Citric Acid Cycle, Breast Neoplasms, Antineoplastic Agents, Pyrimidinones, Thiophenes, Biology, General Biochemistry, Genetics and Molecular Biology, Article, Cell Line, 03 medical and health sciences, Internal medicine, Cell Line, Tumor, Breast Cancer, medicine, Animals, Humans, Cell Proliferation, Neoplastic, Cell growth, Gene Expression Profiling, Epithelial Cells, Biological Transport, Xenograft Model Antitumor Assays, Citric acid cycle, 030104 developmental biology, Endocrinology, chemistry, Gene Expression Regulation, Cancer cell, Cancer research, biology.protein, Pyruvic acid, Biochemistry and Cell Biology
وصف الملف: application/pdf
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::561d2c663223b9c9462134d4401b6775
https://escholarship.org/uc/item/92p5w832 -
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المؤلفون: Nichole E. LaPointe, Michael T. Bowers, David B. Teplow, Pascal Krotee, David Eisenberg, Sarah Quan, Brittany Ulrich, Joan-Emma Shea, Thanh D. Do, Stuart C. Feinstein, Rebecca Nelson, Eric Y. Hayden
المصدر: Journal of the American Chemical Society, vol 138, iss 2
مصطلحات موضوعية: 0301 basic medicine, Aging, Protein Conformation, Peptide, Neurodegenerative, Alzheimer's Disease, 01 natural sciences, Biochemistry, law.invention, Colloid and Surface Chemistry, Protein structure, law, Diglycine, 2.1 Biological and endogenous factors, Peptide sequence, chemistry.chemical_classification, Microscopy, Chemistry, Electrospray Ionization, P3 peptide, Blood Proteins, Blood proteins, Neurological, medicine.drug, Spectrometry, Mass, Electrospray Ionization, 1.1 Normal biological development and functioning, 010402 general chemistry, Electron, Article, Catalysis, 03 medical and health sciences, Microscopy, Electron, Transmission, medicine, Acquired Cognitive Impairment, Transmission, Amino Acid Sequence, Amyloid beta-Peptides, Spectrometry, Neurosciences, Alzheimer's Disease including Alzheimer's Disease Related Dementias (AD/ADRD), General Chemistry, Mass, 0104 chemical sciences, Brain Disorders, 030104 developmental biology, Chemical Sciences, Dementia, Electron microscope, Protein C
وصف الملف: application/pdf
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::276932668262d1800df625cd16a484ff
https://escholarship.org/uc/item/2dz88741 -
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المؤلفون: Marie E. Oskarsson, Gunilla T. Westermark, Pascal Krotee, Michael R. Sawaya, Jose A. Rodriguez, Johan Hattne, Tamir Gonen, Francis E. Reyes, Dan Shi, David Eisenberg, Lin Jiang, Duilio Cascio, Brent L. Nannenga
المصدر: Biophysical Journal. 112:14a
مصطلحات موضوعية: Type ii diabetes, Crystallography, Chemistry, Cryo-electron microscopy, Biophysics, macromolecular substances
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المؤلفون: Robyn M. Kaake, Pascal Krotee, Vishal R. Patel, Thomas Whisenant, Lan Huang, William Gordon, Lee Bardwell, Elizabeth A. Gordon, Michael Zeller, Pierre Baldi
المصدر: Cellular signalling, vol 25, iss 12
Gordon, EA; Whisenant, TC; Zeller, M; Kaake, RM; Gordon, WM; Krotee, P; et al.(2013). Combining docking site and phosphosite predictions to find new substrates: Identification of smoothelin-like-2 (SMTNL2) as a c-Jun N-terminal kinase (JNK) substrate. Cellular Signalling, 25(12), 2518-2529. doi: 10.1016/j.cellsig.2013.08.004. UC Irvine: Retrieved from: http://www.escholarship.org/uc/item/4qw9c50pمصطلحات موضوعية: Biochemistry & Molecular Biology, 1.1 Normal biological development and functioning, Molecular Sequence Data, Medical Physiology, Article, Cell Line, Substrate Specificity, Docking, Myoblasts, Mice, Underpinning research, Genetics, Animals, Humans, Amino Acid Sequence, Binding site, Phosphorylation, Peptide sequence, SMTNL2, Binding Sites, biology, Kinase, c-jun, JNK Mitogen-Activated Protein Kinases, D-site, Cell Biology, Phosphoproteins, HEK293 Cells, Biochemistry, Docking (molecular), Mitogen-activated protein kinase, biology.protein, Smoothelin, MAP kinase, JNK, Generic health relevance, Biochemistry and Cell Biology
وصف الملف: application/pdf
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b2141c1b7733606ff4249e4ea1e39973
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المؤلفون: S.H. Choi, Trias Thireou, J.P. Fuhrer, Spiros D. Dimitratos, Brigida Rusconi, F. Grun, Daniel F. Woods, A.C. Maranhao, Elias Eliopoulos, Osvaldo Marinotti, Pascal Krotee, Marika F. Walter
المصدر: Biochimica et Biophysica Acta (BBA)-Proteins and Proteomics; Vol 1824
مصطلحات موضوعية: Models, Molecular, Circular dichroism, Anopheles gambiae, Molecular Sequence Data, Biophysics, Biology, Ligands, Receptors, Odorant, Biochemistry, Article, Analytical Chemistry, 03 medical and health sciences, Protein structure, Anopheles, Animals, Point Mutation, Amino Acid Sequence, Binding site, Site-directed mutagenesis, Molecular Biology, Peptide sequence, 030304 developmental biology, 0303 health sciences, Binding Sites, Point mutation, Ligand binding assay, Circular Dichroism, 030302 biochemistry & molecular biology, biology.organism_classification, Molecular biology, 3. Good health, 1-Naphthylamine, Mutagenesis, Site-Directed, Insect Proteins
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa1b943bdd8d5bd1020605a0d4ce6bb7
https://pubmed.ncbi.nlm.nih.gov/22564768