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المؤلفون: Sandigawad, AM, Patil, CG
المصدر: African Journal of Biotechnology; Vol 10, No 19 (2011); 3682-3688
وصف الملف: application/pdf
URL الوصول: https://explore.openaire.eu/search/publication?articleId=78975075580c::78157dc12e6022d7ad095425b16eb787
https://www.ajol.info/index.php/ajb/article/view/93456 -
2دورية أكاديمية
المصدر: Spine (03622436); 6/1/2008, Vol. 33 Issue 13, p1491-1496, 6p
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3دورية أكاديمية
المصدر: Spine (03622436); 5/15/2008, Vol. 33 Issue 11, p1250-1255, 6p
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4دورية أكاديمية
المؤلفون: Nisson PL; Department of Neurosurgery, Cedars-Sinai Medical Center, Los Angeles, CA, USA. peyton.nisson@cshs.org., Francis JJ; Department of Neurosurgery, Cedars-Sinai Medical Center, Los Angeles, CA, USA.; School of Medicine, Case Western Reserve University, Cleveland, OH, USA., Michel M; Department of Neurosurgery, Cedars-Sinai Medical Center, Los Angeles, CA, USA.; College of Medicine, University of Florida, Gainesville, FL, USA., Goel K; David Geffen School of Medicine, University of California Los Angeles, Los Angeles, CA, USA., Patil CG; Department of Neurosurgery, Cedars-Sinai Medical Center, Los Angeles, CA, USA.
المصدر: GeroScience [Geroscience] 2024 Aug; Vol. 46 (4), pp. 3543-3553. Date of Electronic Publication: 2024 Jan 30.
نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't
بيانات الدورية: Publisher: Springer International Publishing Country of Publication: Switzerland NLM ID: 101686284 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2509-2723 (Electronic) Linking ISSN: 25092723 NLM ISO Abbreviation: Geroscience Subsets: MEDLINE
مواضيع طبية MeSH: Hematoma, Subdural, Chronic*/surgery, Humans ; Male ; Female ; Aged, 80 and over ; Aged ; Retrospective Studies ; Treatment Outcome ; Age Factors ; Postoperative Complications/epidemiology ; Length of Stay/statistics & numerical data ; Reoperation/statistics & numerical data ; Neurosurgical Procedures/methods ; Kaplan-Meier Estimate
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5دورية أكاديمية
المؤلفون: Baloh RH; Board of Governors Regenerative Medicine Institute, Cedars-Sinai Medical Center, Los Angeles, CA, USA.; Department of Neurology, Cedars-Sinai Medical Center, Los Angeles, CA, USA.; Novartis Institutes for BioMedical Research, Cambridge, MA, USA., Johnson JP; Cedars-Sinai Spine Center, Los Angeles, CA, USA., Avalos P; Board of Governors Regenerative Medicine Institute, Cedars-Sinai Medical Center, Los Angeles, CA, USA., Allred P; Department of Neurology, Cedars-Sinai Medical Center, Los Angeles, CA, USA.; Novartis Institutes for BioMedical Research, Cambridge, MA, USA., Svendsen S; Board of Governors Regenerative Medicine Institute, Cedars-Sinai Medical Center, Los Angeles, CA, USA., Gowing G; Board of Governors Regenerative Medicine Institute, Cedars-Sinai Medical Center, Los Angeles, CA, USA.; Fujifilm Cellular Dynamics, Inc., Madison, WI, USA., Roxas K; Board of Governors Regenerative Medicine Institute, Cedars-Sinai Medical Center, Los Angeles, CA, USA., Wu A; Board of Governors Regenerative Medicine Institute, Cedars-Sinai Medical Center, Los Angeles, CA, USA., Donahue B; Board of Governors Regenerative Medicine Institute, Cedars-Sinai Medical Center, Los Angeles, CA, USA., Osborne S; Board of Governors Regenerative Medicine Institute, Cedars-Sinai Medical Center, Los Angeles, CA, USA., Lawless G; Board of Governors Regenerative Medicine Institute, Cedars-Sinai Medical Center, Los Angeles, CA, USA., Shelley B; Board of Governors Regenerative Medicine Institute, Cedars-Sinai Medical Center, Los Angeles, CA, USA.; Fujifilm Cellular Dynamics, Inc., Madison, WI, USA., Wheeler K; Department of Neurology, Cedars-Sinai Medical Center, Los Angeles, CA, USA.; USC Mark and Mary Stevens Neuroimaging and Informatics Institute, Los Angeles, CA, USA., Prina C; Department of Neurology, Cedars-Sinai Medical Center, Los Angeles, CA, USA., Fine D; Department of Neurology, Cedars-Sinai Medical Center, Los Angeles, CA, USA., Kendra-Romito T; Department of Neurology, Cedars-Sinai Medical Center, Los Angeles, CA, USA., Stokes H; Department of Neurology, Cedars-Sinai Medical Center, Los Angeles, CA, USA., Manoukian V; Department of Neurology, Cedars-Sinai Medical Center, Los Angeles, CA, USA., Muthukumaran A; Department of Neurology, Cedars-Sinai Medical Center, Los Angeles, CA, USA., Garcia L; Board of Governors Regenerative Medicine Institute, Cedars-Sinai Medical Center, Los Angeles, CA, USA., Bañuelos MG; Board of Governors Regenerative Medicine Institute, Cedars-Sinai Medical Center, Los Angeles, CA, USA., Godoy M; Board of Governors Regenerative Medicine Institute, Cedars-Sinai Medical Center, Los Angeles, CA, USA.; Department of Psychiatry and Biobehavioral Sciences, UCLA, Los Angeles, CA, USA., Bresee C; Biostatistics Core, Cedars-Sinai Medical Center, Los Angeles, CA, USA., Yu H; Department of Neurology, Massachusetts General Hospital, Boston, MA, USA., Drazin D; Department of Neurosurgery, Cedars-Sinai Medical Center, Los Angeles, CA, USA.; Department of Neurosurgery, Providence Regional Medical Center Everett, Everett, WA, USA., Ross L; Department of Neurosurgery, Cedars-Sinai Medical Center, Los Angeles, CA, USA., Naruse R; Department of Anesthesiology, Cedars-Sinai Medical Center, Los Angeles, CA, USA., Babu H; Department of Neurosurgery, Cedars-Sinai Medical Center, Los Angeles, CA, USA.; Department of Neurosurgery, SUNY-Upstate Medical University, Syracuse, NY, USA., Macklin EA; Biostatistics Center, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA., Vo A; Cedars-Sinai Comprehensive Transplant Center, Los Angeles, CA, USA., Elsayegh A; Department of Pulmonary and Critical Care, Cedars-Sinai Medical Center, Los Angeles, CA, USA., Tourtellotte W; Department of Neurology, Cedars-Sinai Medical Center, Los Angeles, CA, USA.; Department of Neurosurgery, Cedars-Sinai Medical Center, Los Angeles, CA, USA.; Department of Pathology and Laboratory Medicine, Cedars-Sinai Medical Center, Los Angeles, CA, USA., Maya M; Department of Imaging, Cedars-Sinai Medical Center, Los Angeles, CA, USA., Burford M; Department of Neurology, Cedars-Sinai Medical Center, Los Angeles, CA, USA., Diaz F; Department of Neurology, Cedars-Sinai Medical Center, Los Angeles, CA, USA., Patil CG; Department of Neurosurgery, Cedars-Sinai Medical Center, Los Angeles, CA, USA., Lewis RA; Department of Neurology, Cedars-Sinai Medical Center, Los Angeles, CA, USA., Svendsen CN; Board of Governors Regenerative Medicine Institute, Cedars-Sinai Medical Center, Los Angeles, CA, USA. Clive.svendsen@cshs.org.
المصدر: Nature medicine [Nat Med] 2022 Sep; Vol. 28 (9), pp. 1813-1822. Date of Electronic Publication: 2022 Sep 05.
نوع المنشور: Clinical Trial, Phase I; Clinical Trial, Phase II; Journal Article; Research Support, U.S. Gov't, Non-P.H.S.
بيانات الدورية: Publisher: Nature Publishing Company Country of Publication: United States NLM ID: 9502015 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1546-170X (Electronic) Linking ISSN: 10788956 NLM ISO Abbreviation: Nat Med Subsets: MEDLINE
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6دورية أكاديمية
المؤلفون: Hu JL; Department of Medicine, Cedars-Sinai Medical Center, Los Angeles, California.; Department of Neurosurgery, Cedars-Sinai Medical Center, Los Angeles, California., Omofoye OA; Department of Neurosurgery, Cedars-Sinai Medical Center, Los Angeles, California., Rudnick JD; Department of Medicine, Cedars-Sinai Medical Center, Los Angeles, California., Kim S; Department of Medicine, Cedars-Sinai Medical Center, Los Angeles, California., Tighiouart M; Department of Medicine, Cedars-Sinai Medical Center, Los Angeles, California., Phuphanich S; Department of Medicine, Cedars-Sinai Medical Center, Los Angeles, California., Wang H; Department of Neurosurgery, Cedars-Sinai Medical Center, Los Angeles, California., Mazer M; Department of Neurosurgery, Cedars-Sinai Medical Center, Los Angeles, California., Ganaway T; Department of Neurosurgery, Cedars-Sinai Medical Center, Los Angeles, California., Chu RM; Department of Neurosurgery, Cedars-Sinai Medical Center, Los Angeles, California., Patil CG; Department of Neurosurgery, Cedars-Sinai Medical Center, Los Angeles, California., Black KL; Department of Neurosurgery, Cedars-Sinai Medical Center, Los Angeles, California., Shiao SL; Department of Radiation Oncology, Cedars-Sinai Medical Center, Los Angeles, California., Wang R; Department of Pediatrics, Children's Hospital Los Angeles, Los Angeles, California.; Department of Medicine, Norris Comprehensive Cancer Center, The Keck School of Medicine at the University of Southern California, Los Angeles, California., Yu JS; Department of Neurosurgery, Cedars-Sinai Medical Center, Los Angeles, California.
المصدر: Clinical cancer research : an official journal of the American Association for Cancer Research [Clin Cancer Res] 2022 Feb 15; Vol. 28 (4), pp. 689-696.
نوع المنشور: Clinical Trial, Phase I; Journal Article; Research Support, Non-U.S. Gov't
بيانات الدورية: Publisher: The Association Country of Publication: United States NLM ID: 9502500 Publication Model: Print Cited Medium: Internet ISSN: 1557-3265 (Electronic) Linking ISSN: 10780432 NLM ISO Abbreviation: Clin Cancer Res Subsets: MEDLINE
مواضيع طبية MeSH: Brain Neoplasms*/pathology , Cancer Vaccines* , Glioblastoma*/pathology , Hematopoietic Stem Cell Transplantation*, Cell Line ; Dendritic Cells ; Humans ; Neoplasm Recurrence, Local/drug therapy
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7دورية أكاديمية
المؤلفون: Dhawan S; University of Minnesota, Department of Neurosurgery, 420 Delaware St. SE, D429 Mayo, Minneapolis, Minnesota, USA, 55455., Patil CG; Maxine Dunitz Neurosurgical Institute, Department of Neurosurgery, Cedars-Sinai Medical Center, 8631 West Third Street, Suite 800E, Los Angeles, CA, USA, 90048., Chen C; University of Minnesota, Department of Neurosurgery, 420 Delaware St. SE, D429 Mayo, Minneapolis, Minnesota, USA, 55455., Venteicher AS; University of Minnesota, Department of Neurosurgery, 420 Delaware St. SE, D429 Mayo, Minneapolis, Minnesota, USA, 55455.
المصدر: The Cochrane database of systematic reviews [Cochrane Database Syst Rev] 2020 Jan 20; Vol. 1. Cochrane AN: CD009229. Date of Electronic Publication: 2020 Jan 20.
نوع المنشور: Journal Article; Meta-Analysis; Research Support, Non-U.S. Gov't; Systematic Review
بيانات الدورية: Publisher: Wiley Country of Publication: England NLM ID: 100909747 Publication Model: Electronic Cited Medium: Internet ISSN: 1469-493X (Electronic) Linking ISSN: 13616137 NLM ISO Abbreviation: Cochrane Database Syst Rev Subsets: MEDLINE
مواضيع طبية MeSH: Brain Neoplasms/*radiotherapy , Glioma/*radiotherapy, Brain Neoplasms/mortality ; Brain Neoplasms/surgery ; Disease-Free Survival ; Glioma/surgery ; Humans ; Postoperative Care ; Progression-Free Survival ; Radiosurgery ; Radiotherapy/methods ; Randomized Controlled Trials as Topic ; Time Factors ; Watchful Waiting
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8دورية أكاديمية
المؤلفون: Patil CG; Cedars-Sinai Medical Center, Los Angeles, California., Walker DG; NEWRO Foundation, Brisbane, Australia.; Dermatology Research Centre, The University of Queensland, The University of Queensland Diamantina Institute, Brisbane, Australia., Miller DM; Blaze Bioscience, Inc, Seattle, Washington., Butte P; Cedars-Sinai Medical Center, Los Angeles, California., Morrison B; NEWRO Foundation, Brisbane, Australia., Kittle DS; Blaze Bioscience, Inc, Seattle, Washington., Hansen SJ; Blaze Bioscience, Inc, Seattle, Washington., Nufer KL; Dermatology Research Centre, The University of Queensland, The University of Queensland Diamantina Institute, Brisbane, Australia., Byrnes-Blake KA; Northwest PK Solutions, LLC, Sultan, Washington., Yamada M; Dermatology Research Centre, The University of Queensland, The University of Queensland Diamantina Institute, Brisbane, Australia.; Future Industries Institute, University of South Australia, Adelaide, Australia., Lin LL; Dermatology Research Centre, The University of Queensland, The University of Queensland Diamantina Institute, Brisbane, Australia., Pham K; Dermatology Research Centre, The University of Queensland, The University of Queensland Diamantina Institute, Brisbane, Australia., Perry J; Blaze Bioscience, Inc, Seattle, Washington., Parrish-Novak J; Blaze Bioscience, Inc, Seattle, Washington., Ishak L; Blaze Bioscience, Inc, Seattle, Washington., Prow T; Dermatology Research Centre, The University of Queensland, The University of Queensland Diamantina Institute, Brisbane, Australia.; Future Industries Institute, University of South Australia, Adelaide, Australia., Black K; Cedars-Sinai Medical Center, Los Angeles, California., Mamelak AN; Cedars-Sinai Medical Center, Los Angeles, California.
المصدر: Neurosurgery [Neurosurgery] 2019 Oct 01; Vol. 85 (4), pp. E641-E649.
نوع المنشور: Clinical Trial, Phase I; Journal Article; Multicenter Study; Research Support, Non-U.S. Gov't
بيانات الدورية: Publisher: Lippincott Williams & Wilkins, Inc Country of Publication: United States NLM ID: 7802914 Publication Model: Print Cited Medium: Internet ISSN: 1524-4040 (Electronic) Linking ISSN: 0148396X NLM ISO Abbreviation: Neurosurgery Subsets: MEDLINE
مواضيع طبية MeSH: Brain Neoplasms/*diagnostic imaging , Glioma/*diagnostic imaging , Indocyanine Green/*analogs & derivatives , Neoplasm Recurrence, Local/*diagnostic imaging , Optical Imaging/*methods , Scorpion Venoms/*administration & dosage , Scorpion Venoms/*pharmacokinetics, Adult ; Aged ; Brain Neoplasms/metabolism ; Brain Neoplasms/surgery ; Dose-Response Relationship, Drug ; Female ; Fluorescent Dyes/administration & dosage ; Fluorescent Dyes/pharmacokinetics ; Glioma/metabolism ; Glioma/surgery ; Humans ; Indocyanine Green/administration & dosage ; Indocyanine Green/pharmacokinetics ; Injections, Intravenous ; Male ; Middle Aged ; Neoplasm Recurrence, Local/metabolism ; Neoplasm Recurrence, Local/surgery
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9دورية أكاديمية
المؤلفون: Sun T; Nanomedicine Research Center, Department of Neurosurgery, Cedars-Sinai Medical Center, Los Angeles, California., Patil R; Nanomedicine Research Center, Department of Neurosurgery, Cedars-Sinai Medical Center, Los Angeles, California.; Samuel Oschin Comprehensive Cancer Center, Cedars-Sinai Medical Center, Los Angeles, California., Galstyan A; Nanomedicine Research Center, Department of Neurosurgery, Cedars-Sinai Medical Center, Los Angeles, California., Klymyshyn D; Nanomedicine Research Center, Department of Neurosurgery, Cedars-Sinai Medical Center, Los Angeles, California., Ding H; Nanomedicine Research Center, Department of Neurosurgery, Cedars-Sinai Medical Center, Los Angeles, California.; Samuel Oschin Comprehensive Cancer Center, Cedars-Sinai Medical Center, Los Angeles, California., Chesnokova A; Nanomedicine Research Center, Department of Neurosurgery, Cedars-Sinai Medical Center, Los Angeles, California., Cavenee WK; Ludwig Institute for Cancer Research, University of California San Diego, La Jolla, California., Furnari FB; Ludwig Institute for Cancer Research, University of California San Diego, La Jolla, California., Ljubimov VA; Department of Neurosurgery, Cedars-Sinai Medical Center, Los Angeles, California., Shatalova ES; Nanomedicine Research Center, Department of Neurosurgery, Cedars-Sinai Medical Center, Los Angeles, California., Wagner S; Biomedical Imaging Research Institute, Cedars-Sinai Medical Center, Los Angeles, California., Li D; Biomedical Imaging Research Institute, Cedars-Sinai Medical Center, Los Angeles, California., Mamelak AN; Samuel Oschin Comprehensive Cancer Center, Cedars-Sinai Medical Center, Los Angeles, California.; Department of Neurosurgery, Cedars-Sinai Medical Center, Los Angeles, California., Bannykh SI; Samuel Oschin Comprehensive Cancer Center, Cedars-Sinai Medical Center, Los Angeles, California.; Department of Pathology and Laboratory Medicine, Cedars-Sinai Medical Center, Los Angeles, California., Patil CG; Department of Neurosurgery, Cedars-Sinai Medical Center, Los Angeles, California., Rudnick JD; Samuel Oschin Comprehensive Cancer Center, Cedars-Sinai Medical Center, Los Angeles, California.; Department of Neurosurgery, Cedars-Sinai Medical Center, Los Angeles, California., Hu J; Samuel Oschin Comprehensive Cancer Center, Cedars-Sinai Medical Center, Los Angeles, California.; Department of Neurosurgery, Cedars-Sinai Medical Center, Los Angeles, California., Grodzinski ZB; Nanomedicine Research Center, Department of Neurosurgery, Cedars-Sinai Medical Center, Los Angeles, California., Rekechenetskiy A; St. George's University c/o University Support Services, LLC, Great River, New York., Falahatian V; Duke University School of Medicine, Department of Biostatistics and Bioinformatics, Clinical Research Training Program (CRTP), Durham, North Carolina., Lyubimov AV; Toxicology Research Laboratory (TRL), Department of Pharmacology, University of Illinois at Chicago, Chicago, Illinois., Chen YL; Toxicology Research Laboratory (TRL), Department of Pharmacology, University of Illinois at Chicago, Chicago, Illinois., Leoh LS; Division of Surgical Oncology, Department of Surgery, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, California., Daniels-Wells TR; Division of Surgical Oncology, Department of Surgery, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, California., Penichet ML; Division of Surgical Oncology, Department of Surgery, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, California.; Department of Microbiology, Immunology and Molecular Genetics, David Geffen School of Medicine at University of California, Los Angeles; Jonsson Comprehensive Cancer Center, the Molecular Biology Institute, AIDS Institute, the California NanoSystems Institute, University of California, Los Angeles, Los Angeles, California., Holler E; Nanomedicine Research Center, Department of Neurosurgery, Cedars-Sinai Medical Center, Los Angeles, California.; Samuel Oschin Comprehensive Cancer Center, Cedars-Sinai Medical Center, Los Angeles, California.; Institut für Biophysik und Physikalische Biochemie, Universität Regensburg, Regensburg, Germany., Ljubimov AV; Samuel Oschin Comprehensive Cancer Center, Cedars-Sinai Medical Center, Los Angeles, California.; Department of Neurosurgery, Cedars-Sinai Medical Center, Los Angeles, California.; Department of Biomedical Sciences, Board of Governors Regenerative Medicine Institute, Cedars-Sinai Medical Center, Los Angeles, California., Black KL; Nanomedicine Research Center, Department of Neurosurgery, Cedars-Sinai Medical Center, Los Angeles, California.; Samuel Oschin Comprehensive Cancer Center, Cedars-Sinai Medical Center, Los Angeles, California.; Department of Neurosurgery, Cedars-Sinai Medical Center, Los Angeles, California., Ljubimova JY; Nanomedicine Research Center, Department of Neurosurgery, Cedars-Sinai Medical Center, Los Angeles, California. ljubimovaj@cshs.org.; Samuel Oschin Comprehensive Cancer Center, Cedars-Sinai Medical Center, Los Angeles, California.; Department of Neurosurgery, Cedars-Sinai Medical Center, Los Angeles, California.
المصدر: Cancer research [Cancer Res] 2019 Mar 15; Vol. 79 (6), pp. 1239-1251. Date of Electronic Publication: 2019 Jan 18.
نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
بيانات الدورية: Publisher: American Association for Cancer Research Country of Publication: United States NLM ID: 2984705R Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1538-7445 (Electronic) Linking ISSN: 00085472 NLM ISO Abbreviation: Cancer Res Subsets: MEDLINE
مواضيع طبية MeSH: CRISPR-Cas Systems* , Tumor Microenvironment*, Glioblastoma/*pathology , Laminin/*metabolism , Nanoparticles/*chemistry , Neoplastic Stem Cells/*pathology , Receptors, Notch/*metabolism, Animals ; Apoptosis ; Biomarkers, Tumor/genetics ; Biomarkers, Tumor/metabolism ; Brain/metabolism ; Brain/pathology ; Cell Proliferation ; Gene Expression Regulation, Neoplastic ; Glioblastoma/genetics ; Glioblastoma/metabolism ; Humans ; Laminin/antagonists & inhibitors ; Laminin/genetics ; Mice ; Mice, Nude ; Neoplastic Stem Cells/metabolism ; Prognosis ; Receptors, Notch/genetics ; Signal Transduction ; Survival Rate ; Tumor Cells, Cultured ; Xenograft Model Antitumor Assays
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10دورية أكاديمية
المؤلفون: Hribar KC; Cypre Inc., San Francisco, California (www.cypre.co)., Wheeler CJ; Department of Neurosurgery, Cedars-Sinai Hospital, Los Angeles, California., Bazarov A; Cypre Inc., San Francisco, California (www.cypre.co)., Varshneya K; Department of Neurosurgery, Cedars-Sinai Hospital, Los Angeles, California.; Department of Neurosurgery, Stanford University, Palo Alto, California., Yamada R; Department of Neurosurgery, Cedars-Sinai Hospital, Los Angeles, California., Buckley P; Cypre Inc., San Francisco, California (www.cypre.co)., Patil CG; Department of Neurosurgery, Cedars-Sinai Hospital, Los Angeles, California. chirag.patil@cshs.org.
المصدر: Molecular cancer therapeutics [Mol Cancer Ther] 2019 Mar; Vol. 18 (3), pp. 718-725. Date of Electronic Publication: 2019 Feb 12.
نوع المنشور: Journal Article
بيانات الدورية: Publisher: American Association for Cancer Research, Inc Country of Publication: United States NLM ID: 101132535 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1538-8514 (Electronic) Linking ISSN: 15357163 NLM ISO Abbreviation: Mol Cancer Ther Subsets: MEDLINE
مواضيع طبية MeSH: Carcinoma, Renal Cell/*drug therapy , Glioblastoma/*drug therapy , Spheroids, Cellular/*drug effects , Temozolomide/*pharmacology, Aged ; Animals ; Carcinoma, Renal Cell/pathology ; Cell Culture Techniques ; Cell Line, Tumor ; Cell Proliferation/drug effects ; Clinical Trials as Topic ; Disease Models, Animal ; Female ; Glioblastoma/pathology ; Humans ; Hydrogels/pharmacology ; Male ; Mice ; Progression-Free Survival ; Xenograft Model Antitumor Assays