المؤلفون: Javaid N; Department of Molecular Science and Technology, Ajou University, Suwon, Korea.; S&K Therapeutics, Suwon, Korea., Ahmad B; Department of Molecular Science and Technology, Ajou University, Suwon, Korea.; S&K Therapeutics, Suwon, Korea., Patra MC; Department of Molecular Science and Technology, Ajou University, Suwon, Korea., Choi S; Department of Molecular Science and Technology, Ajou University, Suwon, Korea.; S&K Therapeutics, Suwon, Korea.

المصدر: The FEBS journal [FEBS J] 2024 Jul 14. Date of Electronic Publication: 2024 Jul 14.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Published by Blackwell Pub. on behalf of the Federation of European Biochemical Societies Country of Publication: England NLM ID: 101229646 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1742-4658 (Electronic) Linking ISSN: 1742464X NLM ISO Abbreviation: FEBS J Subsets: MEDLINE

المؤلفون: Haseeb M; S&K Therapeutics, Ajou University, Campus Plaza 418, 199 Worldcup-ro, Yeongtong-gu, Suwon 16502, Korea.; Department of Molecular Science and Technology, Ajou University, Suwon 16499, Korea., Choi YS; Department of Molecular Science and Technology, Ajou University, Suwon 16499, Korea., Patra MC; Department of Molecular Science and Technology, Ajou University, Suwon 16499, Korea., Jeong U; S&K Therapeutics, Ajou University, Campus Plaza 418, 199 Worldcup-ro, Yeongtong-gu, Suwon 16502, Korea.; Department of Molecular Science and Technology, Ajou University, Suwon 16499, Korea., Lee WH; Department of Molecular Science and Technology, Ajou University, Suwon 16499, Korea., Qayyum N; Department of Molecular Science and Technology, Ajou University, Suwon 16499, Korea., Choi H; S&K Therapeutics, Ajou University, Campus Plaza 418, 199 Worldcup-ro, Yeongtong-gu, Suwon 16502, Korea.; Department of Molecular Science and Technology, Ajou University, Suwon 16499, Korea., Kim W; Department of Molecular Science and Technology, Ajou University, Suwon 16499, Korea., Choi S; S&K Therapeutics, Ajou University, Campus Plaza 418, 199 Worldcup-ro, Yeongtong-gu, Suwon 16502, Korea.; Department of Molecular Science and Technology, Ajou University, Suwon 16499, Korea.

المصدر: Journal of chemical information and modeling [J Chem Inf Model] 2024 Jul 08; Vol. 64 (13), pp. 5090-5107. Date of Electronic Publication: 2024 Jun 21.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: American Chemical Society Country of Publication: United States NLM ID: 101230060 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1549-960X (Electronic) Linking ISSN: 15499596 NLM ISO Abbreviation: J Chem Inf Model Subsets: MEDLINE

مواضيع طبية MeSH: Toll-Like Receptor 7*/antagonists & inhibitors , Toll-Like Receptor 7*/metabolism , Toll-Like Receptor 9*/metabolism , Toll-Like Receptor 9*/antagonists & inhibitors , Small Molecule Libraries*/pharmacology , Small Molecule Libraries*/chemistry, Animals ; Mice ; Drug Discovery ; Molecular Docking Simulation ; Signal Transduction/drug effects ; Tumor Necrosis Factor-alpha/metabolism ; Humans

المؤلفون: Javaid N; Department of Molecular Science and Technology, Ajou University, Suwon 16499, Korea., Patra MC; Department of Molecular Science and Technology, Ajou University, Suwon 16499, Korea., Cho DE; Department of Biomedical Sciences, Graduate School, Kyung Hee University, Seoul 02447, Korea., Batool M; Department of Molecular Science and Technology, Ajou University, Suwon 16499, Korea.; S&K Therapeutics, Ajou University Campus Plaza 418, 199 Worldcup-ro, Yeongtong-gu, Suwon 16502, Korea., Kim Y; Department of Biomedical Sciences, Graduate School, Kyung Hee University, Seoul 02447, Korea., Choi GM; Department of Biomedical Sciences, Graduate School, Kyung Hee University, Seoul 02447, Korea., Kim MS; Department of Molecular Science and Technology, Ajou University, Suwon 16499, Korea., Hahm DH; Department of Biomedical Sciences, Graduate School, Kyung Hee University, Seoul 02447, Korea.; Department of Physiology, College of Medicine, Kyung Hee University, Seoul 02447, Korea., Choi S; Department of Molecular Science and Technology, Ajou University, Suwon 16499, Korea.; S&K Therapeutics, Ajou University Campus Plaza 418, 199 Worldcup-ro, Yeongtong-gu, Suwon 16502, Korea.

المصدر: Science signaling [Sci Signal] 2022 Nov 08; Vol. 15 (759), pp. eabi8713. Date of Electronic Publication: 2022 Nov 08.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 101465400 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1937-9145 (Electronic) Linking ISSN: 19450877 NLM ISO Abbreviation: Sci Signal Subsets: MEDLINE

مواضيع طبية MeSH: Arthritis, Experimental*/chemically induced , Arthritis, Experimental*/drug therapy , Arthritis, Rheumatoid*/chemically induced , Arthritis, Rheumatoid*/drug therapy, Mice ; Humans ; Animals ; Tumor Necrosis Factor Inhibitors ; NF-kappa B ; Cytokines ; Receptors, Tumor Necrosis Factor ; Disease Models, Animal

المؤلفون: Manavalan B; Computational Biology and Bioinformatics Lab, Department of Integrative Biotechnology, College of Biotechnology & Bioengineering, Sungkyunkwan University, Seobu-ro, Jangan-gu, Suwon-si, Gyeonggi-do 16419, Republic of Korea. Electronic address: bala2022@skku.edu., Patra MC; Arontier Co., 241 Gangnam-daero, Seocho-gu, Seoul 06735, Republic of Korea.

المصدر: Journal of molecular biology [J Mol Biol] 2022 Jun 15; Vol. 434 (11), pp. 167604. Date of Electronic Publication: 2022 Apr 28.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 2985088R Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1089-8638 (Electronic) Linking ISSN: 00222836 NLM ISO Abbreviation: J Mol Biol Subsets: MEDLINE

مواضيع طبية MeSH: Cell-Penetrating Peptides*/chemistry , Cell-Penetrating Peptides*/metabolism , Internet Use* , Machine Learning* , Software*, Algorithms ; Computational Biology ; Protein Transport

المؤلفون: Javaid N; Department of Molecular Science and Technology, Ajou University, Suwon 16499, Korea., Patra MC; Department of Molecular Science and Technology, Ajou University, Suwon 16499, Korea., Seo H; Department of Molecular Science and Technology, Ajou University, Suwon 16499, Korea., Yasmeen F; Department of Molecular Science and Technology, Ajou University, Suwon 16499, Korea., Choi S; Department of Molecular Science and Technology, Ajou University, Suwon 16499, Korea.; S&K Therapeutics, Woncheon Hall 135, Ajou University, Suwon 16499, Korea.

المصدر: International journal of molecular sciences [Int J Mol Sci] 2020 Dec 11; Vol. 21 (24). Date of Electronic Publication: 2020 Dec 11.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067 (Electronic) Linking ISSN: 14220067 NLM ISO Abbreviation: Int J Mol Sci Subsets: MEDLINE

مواضيع طبية MeSH: Dimethyl Sulfoxide/*pharmacology , Tumor Necrosis Factor-alpha/*pharmacology, Blotting, Western ; Cell Line ; Cell Proliferation/drug effects ; Cell Survival/drug effects ; Cytokines/metabolism ; Fibroblasts/drug effects ; Fibroblasts/metabolism ; Humans ; Receptors, Tumor Necrosis Factor/metabolism ; Signal Transduction/drug effects

المؤلفون: Patra MC; Department of Molecular Science and Technology, Ajou University, Suwon, 16499, Republic of Korea., Shah M; Department of Molecular Science and Technology, Ajou University, Suwon, 16499, Republic of Korea., Choi S; Department of Molecular Science and Technology, Ajou University, Suwon, 16499, Republic of Korea. Electronic address: sangdunchoi@ajou.ac.kr.

المصدر: Seminars in cancer biology [Semin Cancer Biol] 2020 Aug; Vol. 64, pp. 61-82. Date of Electronic Publication: 2019 May 02.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't; Review

بيانات الدورية: Publisher: Academic Press Country of Publication: England NLM ID: 9010218 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1096-3650 (Electronic) Linking ISSN: 1044579X NLM ISO Abbreviation: Semin Cancer Biol Subsets: MEDLINE

مواضيع طبية MeSH: Autoimmune Diseases/*therapy , Cytokines/*immunology , Immunity, Innate/*immunology , Immunotherapy/*methods , Neoplasms/*therapy , Toll-Like Receptors/*metabolism, Animals ; Autoimmune Diseases/immunology ; Autoimmune Diseases/metabolism ; Cytokines/metabolism ; Humans ; Neoplasms/immunology ; Neoplasms/metabolism ; Signal Transduction

المؤلفون: Patra MC; Department of Molecular Science and Technology, Ajou University, Suwon 16499, Korea., Achek A; Department of Molecular Science and Technology, Ajou University, Suwon 16499, Korea., Kim GY; Department of Molecular Science and Technology, Ajou University, Suwon 16499, Korea., Panneerselvam S; Department of Molecular Science and Technology, Ajou University, Suwon 16499, Korea., Shin HJ; Department of Molecular Science and Technology, Ajou University, Suwon 16499, Korea., Baek WY; Department of Rheumatology, Ajou University School of Medicine, Suwon 16499, Korea., Lee WH; Department of Molecular Science and Technology, Ajou University, Suwon 16499, Korea., Sung J; Department of Molecular Science and Technology, Ajou University, Suwon 16499, Korea., Jeong U; Department of Molecular Science and Technology, Ajou University, Suwon 16499, Korea., Cho EY; Department of Molecular Science and Technology, Ajou University, Suwon 16499, Korea., Kim W; Department of Molecular Science and Technology, Ajou University, Suwon 16499, Korea., Kim E; Department of Molecular Science and Technology, Ajou University, Suwon 16499, Korea., Suh CH; Department of Rheumatology, Ajou University School of Medicine, Suwon 16499, Korea., Choi S; Department of Molecular Science and Technology, Ajou University, Suwon 16499, Korea.

المصدر: Cells [Cells] 2020 Jul 09; Vol. 9 (7). Date of Electronic Publication: 2020 Jul 09.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101600052 Publication Model: Electronic Cited Medium: Internet ISSN: 2073-4409 (Electronic) Linking ISSN: 20734409 NLM ISO Abbreviation: Cells Subsets: MEDLINE

مواضيع طبية MeSH: Anti-Inflammatory Agents/*pharmacology , Immunologic Factors/*pharmacology , Lupus Erythematosus, Systemic/*drug therapy , Psoriasis/*drug therapy , Toll-Like Receptors/*antagonists & inhibitors, Animals ; Anti-Inflammatory Agents/chemistry ; Anti-Inflammatory Agents/therapeutic use ; Binding Sites ; Endosomes/metabolism ; Female ; Immunologic Factors/chemistry ; Immunologic Factors/therapeutic use ; Interleukin-6/metabolism ; Mice ; Mice, Inbred C57BL ; Molecular Docking Simulation ; NF-kappa B/metabolism ; Protein Binding ; Quantitative Structure-Activity Relationship ; RAW 264.7 Cells ; Small Molecule Libraries/chemistry ; Small Molecule Libraries/pharmacology ; Toll-Like Receptors/chemistry ; Toll-Like Receptors/metabolism ; Tumor Necrosis Factor-alpha/metabolism

المؤلفون: Patra MC; Department of Molecular Science and Technology, Ajou University, 16499 Suwon, Korea., Batool M; Department of Molecular Science and Technology, Ajou University, 16499 Suwon, Korea., Haseeb M; Department of Molecular Science and Technology, Ajou University, 16499 Suwon, Korea., Choi S; Department of Molecular Science and Technology, Ajou University, 16499 Suwon, Korea.

المصدر: International journal of molecular sciences [Int J Mol Sci] 2020 Apr 19; Vol. 21 (8). Date of Electronic Publication: 2020 Apr 19.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067 (Electronic) Linking ISSN: 14220067 NLM ISO Abbreviation: Int J Mol Sci Subsets: MEDLINE

مواضيع طبية MeSH: Lipid Bilayers/*chemistry , Phospholipids/*chemistry , Toll-Like Receptor 3/*chemistry, Humans ; Hydrophobic and Hydrophilic Interactions ; Models, Molecular ; Molecular Conformation ; Molecular Docking Simulation ; Molecular Dynamics Simulation ; Phospholipids/metabolism ; Protein Binding ; Protein Conformation ; Protein Interaction Domains and Motifs ; RNA, Double-Stranded/chemistry ; RNA, Double-Stranded/metabolism ; Structure-Activity Relationship ; Toll-Like Receptor 3/metabolism

المؤلفون: Achek A; Department of Molecular Science and Technology, Ajou University, Suwon 16499, Republic of Korea., Kwon HK; Department of Orthopaedics and Rehabilitation, Yale School of Medicine, New Haven, CT 06510, USA., Patra MC; Department of Molecular Science and Technology, Ajou University, Suwon 16499, Republic of Korea., Shah M; Department of Molecular Science and Technology, Ajou University, Suwon 16499, Republic of Korea., Hong R; Department of Physiology, School of Medicine, Kyung Hee University, Seoul 02447, Republic of Korea., Lee WH; Department of Molecular Science and Technology, Ajou University, Suwon 16499, Republic of Korea., Baek WY; Department of Rheumatology, Ajou University School of Medicine, Suwon 16499, Republic of Korea., Choi YS; Department of Molecular Science and Technology, Ajou University, Suwon 16499, Republic of Korea., Kim GY; Department of Molecular Science and Technology, Ajou University, Suwon 16499, Republic of Korea., Pham TLH; Department of Molecular Science and Technology, Ajou University, Suwon 16499, Republic of Korea., Suh CH; Department of Rheumatology, Ajou University School of Medicine, Suwon 16499, Republic of Korea., Kim W; Department of Molecular Science and Technology, Ajou University, Suwon 16499, Republic of Korea., Hahm DH; Department of Physiology, School of Medicine, Kyung Hee University, Seoul 02447, Republic of Korea., Choi S; Department of Molecular Science and Technology, Ajou University, Suwon 16499, Republic of Korea. Electronic address: sangdunchoi@ajou.ac.kr.

المصدر: EBioMedicine [EBioMedicine] 2020 Feb; Vol. 52, pp. 102645. Date of Electronic Publication: 2020 Feb 01.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Elsevier B.V Country of Publication: Netherlands NLM ID: 101647039 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2352-3964 (Electronic) Linking ISSN: 23523964 NLM ISO Abbreviation: EBioMedicine Subsets: MEDLINE

مواضيع طبية MeSH: Protein Conformation, beta-Strand*, Membrane Glycoproteins/*chemistry , Peptides/*chemistry , Peptides/*pharmacology , Receptors, Interleukin-1/*chemistry , Toll-Like Receptor 4/*chemistry, Amino Acid Sequence ; Animals ; Anti-Inflammatory Agents/chemistry ; Anti-Inflammatory Agents/pharmacology ; Autoimmunity ; Cell Line ; Cytokines/metabolism ; Disease Models, Animal ; Immunologic Factors/chemistry ; Immunologic Factors/pharmacology ; Inflammation/drug therapy ; Inflammation/etiology ; Inflammation/metabolism ; Inflammation/pathology ; Macrophages/drug effects ; Macrophages/immunology ; Macrophages/metabolism ; Membrane Glycoproteins/metabolism ; Mice ; Models, Molecular ; Nitric Oxide/metabolism ; Peptides/metabolism ; Psoriasis/drug therapy ; Psoriasis/immunology ; Psoriasis/metabolism ; Psoriasis/pathology ; Reactive Oxygen Species/metabolism ; Receptors, Interleukin-1/metabolism ; Signal Transduction ; Structure-Activity Relationship ; Toll-Like Receptor 4/metabolism ; Toll-Like Receptors/metabolism

المؤلفون: Kwon HK; Department of Molecular Science and Technology, Ajou University, Suwon, 16499, Korea.; Division of Nephrology, Department of Internal Medicine, Kyung Hee University Hospital at Gangdong, Seoul, 05278, Korea.; Department of Orthopaedics and Rehabilitation, Yale School of Medicine, New Haven, CT, 06510, USA., Patra MC; Department of Molecular Science and Technology, Ajou University, Suwon, 16499, Korea., Shin HJ; Department of Molecular Science and Technology, Ajou University, Suwon, 16499, Korea., Gui X; Department of Molecular Science and Technology, Ajou University, Suwon, 16499, Korea., Achek A; Department of Molecular Science and Technology, Ajou University, Suwon, 16499, Korea., Panneerselvam S; Department of Molecular Science and Technology, Ajou University, Suwon, 16499, Korea., Kim DJ; Division of Nephrology, Department of Internal Medicine, Kyung Hee University Hospital at Gangdong, Seoul, 05278, Korea., Song SJ; Division of Nephrology, Department of Internal Medicine, Kyung Hee University Hospital at Gangdong, Seoul, 05278, Korea., Hong R; Department of Science in Korean Medicine, College of Korean Medicine, Kyung Hee University, Seoul, 02447, Korea., Kim KS; East-West Bone & Joint Research Institute, Kyung Hee University Hospital at Gangdong, Seoul, 05278, Korea., Kim YG; Division of Nephrology, Department of Internal Medicine, Kyung Hee University Hospital at Gangdong, Seoul, 05278, Korea., Lee FY; Department of Orthopaedics and Rehabilitation, Yale School of Medicine, New Haven, CT, 06510, USA., Hahm DH; Department of Physiology, School of Medicine, Kyung Hee University, Seoul, 02447, Korea., Lee SH; Division of Nephrology, Department of Internal Medicine, Kyung Hee University Hospital at Gangdong, Seoul, 05278, Korea., Choi S; Department of Molecular Science and Technology, Ajou University, Suwon, 16499, Korea. sangdunchoi@ajou.ac.kr.

المصدر: Experimental & molecular medicine [Exp Mol Med] 2019 Apr 26; Vol. 51 (4), pp. 1-19. Date of Electronic Publication: 2019 Apr 26.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Nature Publishing Group Country of Publication: United States NLM ID: 9607880 Publication Model: Electronic Cited Medium: Internet ISSN: 2092-6413 (Electronic) Linking ISSN: 12263613 NLM ISO Abbreviation: Exp Mol Med Subsets: MEDLINE

مواضيع طبية MeSH: Toll-Like Receptors/*metabolism, Animals ; Blotting, Western ; Cell Survival/genetics ; Cell Survival/physiology ; Interferon-beta/metabolism ; Interleukin-1beta/metabolism ; Male ; Mice ; Mice, Inbred BALB C ; Mice, Inbred C57BL ; Microscopy, Confocal ; Peptides/pharmacology ; RAW 264.7 Cells ; Rats, Sprague-Dawley ; Signal Transduction/genetics ; Signal Transduction/physiology ; Toll-Like Receptor 4/genetics ; Toll-Like Receptor 4/metabolism ; Toll-Like Receptors/genetics