نتائج البحث - "Patricia L. Podolin"

1

Discovery of a crystalline sulforaphane analog with good solid-state stability and engagement of the Nrf2 pathway in vitro and in vivo

المصدر: Bioorganic & Medicinal Chemistry. 27:579-588

مصطلحات موضوعية: Antioxidant, NF-E2-Related Factor 2, medicine.medical_treatment, Clinical Biochemistry, Gene Expression, Pharmaceutical Science, medicine.disease_cause, Biochemistry, Antioxidants, Cell Line, Structure-Activity Relationship, chemistry.chemical_compound, Isothiocyanates, Thiocarbamates, In vivo, Drug Discovery, medicine, Animals, Humans, Thermal stability, Molecular Biology, Kelch-Like ECH-Associated Protein 1, Natural product, Molecular Structure, Organic Chemistry, KEAP1, Rats, Mice, Inbred C57BL, Oxidative Stress, Solubility, chemistry, Sulfoxides, Isothiocyanate, Biophysics, Molecular Medicine, Cyclobutanes, Heme Oxygenase-1, Oxidative stress, Signal Transduction, Sulforaphane

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b415f7b6666ea7f677038e87013d3b1
https://doi.org/10.1016/j.bmc.2018.12.026

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2

Characterization of the Potent, Selective Nrf2 Activator, 3-(Pyridin-3-Ylsulfonyl)-5-(Trifluoromethyl)-2H-Chromen-2-One, in Cellular and In Vivo Models of Pulmonary Oxidative Stress

المؤلفون: Jen-Pyng Kou, James F. Callahan, John Yonchuk, Joseph P. Foley, Hong Nie, Heidi G. Feldser, Yolanda Sanchez, William E. Wixted, Jeffrey K. Kerns, Diana G Chalupowicz, Gregory A. Logan, Patricia L. Podolin, Brian Bolognese

المصدر: Journal of Pharmacology and Experimental Therapeutics. 363:114-125

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::204466407cf0cd7f7f72972a187970e8
https://doi.org/10.1124/jpet.117.241794

3

Circadian clock component REV-ERBα controls homeostatic regulation of pulmonary inflammation

المصدر: Pariollaud, M, Gibbs, J, Hopwood, T, Brown, S, Begley, N, Vonslow, R, Poolman, T, Guo, B, Saer, B, Jones, D H, Tellam, J P, Bresciani, S, Tomkinson, N C, Wojno-Picon, J, Cooper, A W, Daniels, D A, Trump, R P, Grant, D, Zuercher, W, Willson, T M, MacDonald, A S, Bolognese, B, Podolin, P L, Sanchez, Y, Loudon, A S & Ray, D W 2018, ' Circadian clock component REV-ERBα controls homeostatic regulation of pulmonary inflammation ', The Journal of clinical investigation, vol. 128, no. 6, pp. 2281-2296 . https://doi.org/10.1172/JCI93910
The Journal of Clinical Investigation

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b850d90e252cb0cef62edd168f157db
https://strathprints.strath.ac.uk/64982/1/Pariollaud_etal_JCI2018_Circadian_clock_component_REV_ERBa_controls_homeostatic_regulation.pdf

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4

Characterization of the Potent, Selective Nrf2 Activator, 3-(Pyridin-3-Ylsulfonyl)-5-(Trifluoromethyl)-2

المؤلفون: John G, Yonchuk, Joseph P, Foley, Brian J, Bolognese, Gregory, Logan, William E, Wixted, Jen-Pyng, Kou, Diana G, Chalupowicz, Heidi G, Feldser, Yolanda, Sanchez, Hong, Nie, James F, Callahan, Jeffrey K, Kerns, Patricia L, Podolin

المصدر: The Journal of pharmacology and experimental therapeutics. 363(1)

URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid________::e6721d8982b84be2d15c27c3ee504816
https://pubmed.ncbi.nlm.nih.gov/28790194

5

Hyperpolarized gas diffusion MRI of biphasic lung inflation in short- and long-term emphysema models

المؤلفون: Rahim R. Rizi, Joseph P. Foley, Yi Xin, Kiarash Emami, Liam Hughes, Maurizio Cereda, Stephen Kadlecek, Natalie Meeder, Hooman Hamedani, Ian Duncan, Harrilla Profka, Jennia Rajaei, Brian Bolognese, Patricia L. Podolin, Joseph Naji

المصدر: American journal of physiology. Lung cellular and molecular physiology. 313(2)

مصطلحات موضوعية: Pulmonary and Respiratory Medicine, Pathology, medicine.medical_specialty, Physiology, Pulmonary emphysema, Respiratory physiology, 030204 cardiovascular system & hematology, Helium, Rats sprague dawley, Rats, Sprague-Dawley, 03 medical and health sciences, Mice, 0302 clinical medicine, Physiology (medical), Internal medicine, Smoke, medicine, Pressure, Effective diffusion coefficient, Animals, Lung, Pancreatic Elastase, Chemistry, Cell Biology, respiratory system, respiratory tract diseases, Rats, Mice, Inbred C57BL, Disease Models, Animal, medicine.anatomical_structure, Diffusion Magnetic Resonance Imaging, 030228 respiratory system, Pulmonary Emphysema, Cardiology, Lung inflation, Research Article

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f1580e56acfdd5ce0d715b9a67c5240
https://pubmed.ncbi.nlm.nih.gov/28473321

6

In vitro and in vivo characterization of a novel soluble epoxide hydrolase inhibitor

المصدر: Prostaglandins & Other Lipid Mediators. :25-31

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e5391100f845f30972b4b633e3a2af2
https://doi.org/10.1016/j.prostaglandins.2013.02.001

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7

Klotho and smoking - An interplay influencing the skeletal muscle function deficits that occur in COPD

المؤلفون: Michael I. Polkey, Y.M. Andersson, Sonya Jackson, Nicholas Hart, Nicholas S Hopkinson, Anna Donaldson, Amy Lewis, Piet L.B. Bruijnzeel, Brian Bolognese, Joseph P. Foley, Mehul S. Patel, Jy Lee, Patricia L. Podolin, GS Haji, Paul R. Kemp, William D.-C. Man, Samantha A. Natanek

المصدر: Patel, M S, Donaldson, A V, Lewis, A, Natanek, S A, Lee, J Y, Andersson, Y M, Haji, G, Jackson, S G, Bolognese, B J, Foley, J P, Podolin, P L, Bruijnzeel, P L B, Hart, N, Hopkinson, N S, D-C Man, W, Kemp, P R & Polkey, M I 2016, ' Klotho and smoking-An interplay influencing the skeletal muscle function deficits that occur in COPD ', Respiratory Medicine . https://doi.org/10.1016/j.rmed.2016.02.004

مصطلحات موضوعية: Male, Pulmonary and Respiratory Medicine, Fibroblast growth factor 23, Spirometry, medicine.medical_specialty, Respiratory System, 030204 cardiovascular system & hematology, urologic and male genital diseases, 1102 Cardiovascular Medicine And Haematology, Klotho, smoking, Quadriceps Muscle, Mice, Pulmonary Disease, Chronic Obstructive, 03 medical and health sciences, 0302 clinical medicine, Internal medicine, medicine, Animals, Humans, COPD, skeletal muscle, Muscle, Skeletal, Klotho Proteins, Wasting, Glucuronidase, medicine.diagnostic_test, business.industry, Smoking, Skeletal muscle, 1103 Clinical Sciences, medicine.disease, Immunohistochemistry, female genital diseases and pregnancy complications, Mice, Inbred C57BL, medicine.anatomical_structure, Endocrinology, 030228 respiratory system, Ageing, regeneration, Regression Analysis, Female, medicine.symptom, business, Hormone