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1دورية أكاديمية
المؤلفون: James B. Murray, James Davidson, Ijen Chen, Ben Davis, Pawel Dokurno, Christopher J. Graham, Richard Harris, Allan Jordan, Natalia Matassova, Christopher Pedder, Stuart Ray, Stephen D. Roughley, Julia Smith, Claire Walmsley, Yikang Wang, Neil Whitehead, Douglas S. Williamson, Patrick Casara, Thierry Le Diguarher, John Hickman, Jerome Stark, András Kotschy, Olivier Geneste, Roderick E. Hubbard
المصدر: ACS Omega, Vol 4, Iss 5, Pp 8892-8906 (2019)
وصف الملف: electronic resource
Relation: https://doaj.org/toc/2470-1343
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المؤلفون: Jean-Marie Delbos, Esther Steidl, Tuulia Huhtala, Aurore Sors, Jean-Michel Arrang, Bruno Buisson, Patrick Casara, Outi Kontkanen, Lionel Bert, Valérie Audinot, Pierre Lestage, Olivier Nosjean, Anne-Marie Chollet, Fany Panayi, Dominique Favale
المصدر: European Journal of Pharmacology. 803:11-23
مصطلحات موضوعية: Male, 0301 basic medicine, Agonist, medicine.medical_specialty, Low protein, Drug Inverse Agonism, medicine.drug_class, Pharmacology, Biology, Hippocampus, Histamine Agonists, Mice, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Internal medicine, Cyclic AMP, medicine, Animals, Humans, Receptors, Histamine H3, Inverse agonist, Receptor, Arachidonic Acid, Dose-Response Relationship, Drug, Histaminergic, Rats, 030104 developmental biology, Endocrinology, chemistry, Benzamides, Histamine H3 receptor, Azabicyclo Compounds, 030217 neurology & neurosurgery, Histamine, Endogenous agonist, Histamine H3 Antagonists
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المؤلفون: Pawel Dokurno, R. Harris, Patrick Casara, James Edward Paul Davidson, Olivier Geneste, Julia Smith, Douglas S. Williamson, Natalia Matassova, Yikang Wang, Allan M. Jordan, Stephen D. Roughley, András Kotschy, Roderick E. Hubbard, Jerome Stark, John A. Hickman, Chen I-Jen, Ben Davis, James Brooke Murray, C. Pedder, Walmsley Claire, Thierry Le Diguarher, Neil Whitehead, Stuart C. Ray, Christopher John Graham
المصدر: ACS Omega
ACS Omega, Vol 4, Iss 5, Pp 8892-8906 (2019)
'ACS Omega ', vol: 4, pages: 8892-8906 (2019)مصطلحات موضوعية: Series (mathematics), Chemistry, Drug discovery, General Chemical Engineering, Isothermal titration calorimetry, General Chemistry, Computational biology, Small molecule, Article, Anti-Apoptotic Proteins, lcsh:Chemistry, Heteronuclear molecule, lcsh:QD1-999, Surface plasmon resonance
وصف الملف: application/pdf
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المؤلفون: Patrick Casara, James Davidson, Audrey Claperon, Gaëtane Le Toumelin-Braizat, Meike Vogler, Alain Bruno, Maïa Chanrion, Gaëlle Lysiak-Auvity, Thierry Le Diguarher, Jérôme-Benoît Starck, Ijen Chen, Neil Whitehead, Christopher Graham, Natalia Matassova, Pawel Dokurno, Christopher Pedder, Youzhen Wang, Shumei Qiu, Anne-Marie Girard, Emilie Schneider, Fabienne Gravé, Aurélie Studeny, Ghislaine Guasconi, Francesca Rocchetti, Sophie Maïga, Jean-Michel Henlin, Frédéric Colland, Laurence Kraus-Berthier, Steven Le Gouill, Martin J.S. Dyer, Roderick Hubbard, Mike Wood, Martine Amiot, Gerald M Cohen, John A. Hickman, Erick Morris, James Murray, Olivier Geneste
المساهمون: Institut de Recherches Servier, Vernalis (R&D) Ltd, Institute for Experimental Cancer Research in Pediatrics, Goethe-Universität Frankfurt am Main, Institut de Recherches Internationales Servier [Suresnes] (IRIS), Novartis Institute of Biomedical Research, Oncology Drug Discovery, Regulation of Bcl2 and p53 Networks in Multiple Myeloma and Mantle Cell Lymphoma (CRCINA-ÉQUIPE 10), Centre de Recherche en Cancérologie et Immunologie Nantes-Angers (CRCINA), Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Nantes - UFR de Médecine et des Techniques Médicales (UFR MEDECINE), Université de Nantes (UN)-Université de Nantes (UN)-Centre hospitalier universitaire de Nantes (CHU Nantes)-Centre National de la Recherche Scientifique (CNRS)-Université d'Angers (UA)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Nantes - UFR de Médecine et des Techniques Médicales (UFR MEDECINE), Université de Nantes (UN)-Université de Nantes (UN)-Centre hospitalier universitaire de Nantes (CHU Nantes)-Centre National de la Recherche Scientifique (CNRS)-Université d'Angers (UA), Ernest and Helen Scott Haematological Research Institute, University of Leicester, Institute of Translational Medicine, University of Liverpool, Goethe-University Frankfurt, Institut de Recherches Internationales Servier [Suresnes] ( IRIS ), Regulation of Bcl2 and p53 networks in Multiple Myeloma and Mantle Cell Lymphoma ( CRCINA - Département NOHMAD - Equipe 10 ), Centre de recherche de Cancérologie et d'Immunologie / Nantes - Angers ( CRCINA ), Université d'Angers ( UA ) -Université de Nantes ( UN ) -Institut National de la Santé et de la Recherche Médicale ( INSERM ) -Centre National de la Recherche Scientifique ( CNRS ) -Institut de Recherche en Santé de l'Université de Nantes ( IRS-UN ) -Centre hospitalier universitaire de Nantes ( CHU Nantes ) -Université d'Angers ( UA ) -Université de Nantes ( UN ) -Institut National de la Santé et de la Recherche Médicale ( INSERM ) -Centre National de la Recherche Scientifique ( CNRS ) -Institut de Recherche en Santé de l'Université de Nantes ( IRS-UN ) -Centre hospitalier universitaire de Nantes ( CHU Nantes ), Université d'Angers (UA)-Université de Nantes (UN)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Centre hospitalier universitaire de Nantes (CHU Nantes)-Université d'Angers (UA)-Université de Nantes (UN)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Centre hospitalier universitaire de Nantes (CHU Nantes), Bernardo, Elizabeth
المصدر: Oncotarget
Oncotarget, Impact journals, 2018, 9 (28), pp.20075-20088. ⟨10.18632/oncotarget.24744⟩
Oncotarget, Impact journals, 2018, 9 (28), pp.20075-20088. 〈10.18632/oncotarget.24744〉
Oncotarget, 2018, 9 (28), pp.20075-20088. ⟨10.18632/oncotarget.24744⟩مصطلحات موضوعية: 0301 basic medicine, apoptosis, BCL-2, [SDV.CAN]Life Sciences [q-bio]/Cancer, BH3-mimetics, [ SDV.CAN ] Life Sciences [q-bio]/Cancer, 3. Good health, inhibitor, 03 medical and health sciences, 030104 developmental biology, 0302 clinical medicine, [SDV.CAN] Life Sciences [q-bio]/Cancer, Oncology, 030220 oncology & carcinogenesis, hematological malignancies, Research Paper
وصف الملف: application/pdf
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a85daeabf79a548e35d6497ffd721f08
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المؤلفون: Gilles Ferry, Philip M. Kubara, Bruno Pfeiffer, Jean-Paul Renaud, Stéphane Léonce, Celine Bossard, Patrick Casara, Michelle Prudhomme, Guillaume de Nanteuil, Roy M. Golsteyn, Alain Pierré, Jean A. Boutin, Michel Wierzbicki, Denis Zeyer, Aurélie Studeny
المصدر: Life Sciences. 89:259-268
مصطلحات موضوعية: animal structures, Cell Survival, medicine.drug_class, Carbazoles, Adenocarcinoma, Spodoptera, Topoisomerase-I Inhibitor, Biology, environment and public health, General Biochemistry, Genetics and Molecular Biology, Cell Line, Tumor, medicine, Animals, Humans, CHEK1, General Pharmacology, Toxicology and Pharmaceutics, Protein kinase A, DNA-PKcs, DNA, Neoplasm, General Medicine, G2-M DNA damage checkpoint, Cell cycle, Cell biology, enzymes and coenzymes (carbohydrates), Biochemistry, Checkpoint Kinase 1, Colonic Neoplasms, Cancer cell, Drug Screening Assays, Antitumor, Topoisomerase I Inhibitors, biological phenomena, cell phenomena, and immunity, Protein Kinases, Topoisomerase inhibitor, DNA Damage
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المؤلفون: John A. Hickman, Ellen Van Obberghen-Schilling, Patrick Casara, Saint-Dizier Dominique, Morgane Boutillon, Gordon C. Tucker, Françoise Perron-Sierra, Sylvie Maubant
المصدر: Blood. 108:3035-3044
مصطلحات موضوعية: 0303 health sciences, Integrin alphaVbeta3, Cell adhesion molecule, Angiogenesis, Immunology, Integrin, Cell Biology, Hematology, Biology, Biochemistry, Cell biology, Endothelial stem cell, Fibronectin, 03 medical and health sciences, 0302 clinical medicine, 030220 oncology & carcinogenesis, Thrombospondin 1, biology.protein, Anoikis, 030304 developmental biology
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::edc89b3d4de4392e1b65b98d6e344313
https://doi.org/10.1182/blood-2006-05-023580 -
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المؤلفون: Bruno Pfeiffer, Armelle Loynel, Nathalie Kucharczyk, Hélène Henon, Fabrice Anizon, Patrick Casara, Michelle Prudhomme
المصدر: Synthesis. 2006:711-715
مصطلحات موضوعية: 010404 medicinal & biomolecular chemistry, chemistry.chemical_compound, Granulatimide, 010405 organic chemistry, Chemistry, Carbazole, Stereochemistry, Organic Chemistry, 01 natural sciences, Combinatorial chemistry, Catalysis, 0104 chemical sciences, 3. Good health
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::5a3cac7a8f78fc289e826581625e72b4
https://doi.org/10.1055/s-2006-926308 -
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المؤلفون: Mike Burbridge, Patrick Casara, Gordon C. Tucker, Perron-Sierra Francoise, Christophe Péan
المصدر: Tetrahedron Letters. 45:4163-4166
مصطلحات موضوعية: carbohydrates (lipids), chemistry.chemical_compound, biology, chemistry, Sialyltransferase, Stereochemistry, Organic Chemistry, Drug Discovery, biology.protein, Sialidase, Biochemistry, Derivative (chemistry), Sialic acid
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المؤلفون: Thierry Le Diguarher, Eric Raimbaud, Patrick Casara, Marc Bertrand, Massimo Sabatini, Nicolas Guilbaud, Alain Pierre, Anne-Marie Chollet, Gordon C. Tucker, Philippe Hennig
المصدر: Journal of Medicinal Chemistry. 46:3840-3852
مصطلحات موضوعية: Models, Molecular, Matrix metalloproteinase inhibitor, Stereochemistry, Carboxylic acid, Melanoma, Experimental, Molecular Conformation, Administration, Oral, Biological Availability, Antineoplastic Agents, Phthalimides, Cyclopentanes, In Vitro Techniques, Matrix Metalloproteinase Inhibitors, Matrix metalloproteinase, Chemical synthesis, Permeability, Mice, Structure-Activity Relationship, chemistry.chemical_compound, Stereospecificity, Drug Discovery, Animals, Humans, Protease Inhibitors, Neoplasm Metastasis, Cyclopentane, chemistry.chemical_classification, Bicyclic molecule, biology, Triazines, Stereoisomerism, Matrix Metalloproteinases, chemistry, Enzyme inhibitor, Microsomes, Liver, biology.protein, Molecular Medicine, Caco-2 Cells
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المؤلفون: Nicolas Guilbaud, Gordon C. Tucker, Alain Pierre, Jean Luc Fauchère, Thierry Le Diguarher, John A. Hickman, David Shanks, Gilbert Dorey, Patrick Casara, Jean Claude Ortuno
المصدر: Bioorganic & Medicinal Chemistry. 11:3193-3204
مصطلحات موضوعية: Lactams, Nitrile, Stereochemistry, Clinical Biochemistry, Pharmaceutical Science, Antineoplastic Agents, Biochemistry, Chemical synthesis, Mice, Structure-Activity Relationship, chemistry.chemical_compound, In vivo, Cell Line, Tumor, Drug Discovery, Animals, Farnesyltranstransferase, Amines, Enzyme Inhibitors, Molecular Biology, chemistry.chemical_classification, Farnesyl-diphosphate farnesyltransferase, Alkyl and Aryl Transferases, Molecular Structure, biology, Farnesyl Transferase Inhibitor, Organic Chemistry, Imidazoles, Azepines, Rats, Enzyme, chemistry, Enzyme inhibitor, biology.protein, Lactam, Molecular Medicine, Drug Screening Assays, Antitumor