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المؤلفون: Jeong-Han Kang, Patrick L. Splinter, Christy E. Trussoni, Nicholas E. Pirius, Gregory J. Gores, Nicholas F. LaRusso, Steven P. O’Hara
المصدر: Gastroenterology.
مصطلحات موضوعية: Hepatology, Gastroenterology
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2دورية أكاديمية
المصدر: PLoS ONE, Vol 10, Iss 4, p e0125793 (2015)
وصف الملف: electronic resource
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المؤلفون: Lorena Loarca, Lorena Marcano Bonilla, Nicholas F. LaRusso, Maria J. Lorenzo Pisarello, Eugene W. Krueger, Gregory J. Gores, Guang Shi, Anuradha Krishnan, Christy E. Trussoni, Bing Huang, Leslie Morton, Robert C. Huebert, Steve F. Bronk, Patrick L. Splinter, Thiago M. De Assuncao, Nidhi Jalan-Sakrikar, Steve P. O'Hara
المصدر: Laboratory investigation; a journal of technical methods and pathology
مصطلحات موضوعية: 0301 basic medicine, Senescence, Pathology, medicine.medical_specialty, Cellular pathology, Cholangitis, Sclerosing, Autoantigens, Cholangiocyte, Article, Pathology and Forensic Medicine, Primary sclerosing cholangitis, Cell Line, Receptors, G-Protein-Coupled, Receptors, Gastrointestinal Hormone, Pathogenesis, 03 medical and health sciences, Extracellular Vesicles, Western blot, Microscopy, Electron, Transmission, Spheroids, Cellular, medicine, Humans, Molecular Biology, Cells, Cultured, Cellular Senescence, Keratin-19, medicine.diagnostic_test, Chemistry, Macrophages, Keratin-7, Multivesicular Bodies, Membrane Proteins, Cell Biology, Hydrogen Peroxide, Macrophage Activation, medicine.disease, Oxidants, Coculture Techniques, 3. Good health, Cell biology, 030104 developmental biology, Gene Expression Regulation, Cell culture, Culture Media, Conditioned, Secretin receptor, Bile Ducts, Biomarkers
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المؤلفون: Bryce F. Schutte, Christy E. Trussoni, Maria J. Lorenzo Pisarello, Noah S. Splinter, Steven P. O'Hara, Patrick L. Splinter, Nicholas F. LaRusso, Lorena Loarca
المصدر: Journal of Biological Chemistry. 292:4833-4846
مصطلحات موضوعية: Lipopolysaccharides, Transcriptional Activation, 0301 basic medicine, Neuroblastoma RAS viral oncogene homolog, Senescence, MAPK/ERK pathway, Cholangitis, Sclerosing, Biology, Proto-Oncogene Mas, Biochemistry, Cyclin-Dependent Kinase Inhibitor 2A, Cholangiocyte, Cell Line, Proto-Oncogene Protein c-ets-1, Mice, 03 medical and health sciences, 0302 clinical medicine, ETS1, Animals, Humans, RNA, Messenger, neoplasms, Molecular Biology, Cellular Senescence, Cyclin-Dependent Kinase Inhibitor p16, Oncogene, Kinase, Molecular Bases of Disease, Cell Biology, digestive system diseases, Up-Regulation, 030104 developmental biology, Liver, 030220 oncology & carcinogenesis, Cancer research
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bca3054ee03b861126a77363d9d5a6e3
https://doi.org/10.1074/jbc.m117.777409 -
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المؤلفون: Deborah Stollenwerk, Gregory J. Gores, Patrick L. Splinter, Mohammed S. Al Suraih, Nicholas F. LaRusso, Noah P. Splinter, Christy E. Trussoni, Maria Eugenia Guicciardi, Navine Nasser-Ghodsi, Steven P. O'Hara
المصدر: J Biol Chem
مصطلحات موضوعية: 0301 basic medicine, Senescence, Lipopolysaccharides, ATP Binding Cassette Transporter, Subfamily B, bcl-X Protein, Apoptosis, Biology, BCL2-like 1, Biochemistry, Proto-Oncogene Mas, Cholangiocyte, Proto-Oncogene Protein c-ets-1, 03 medical and health sciences, Mice, ETS1, Gene expression, Animals, Humans, Molecular Biology, Transcription factor, Cellular Senescence, 030102 biochemistry & molecular biology, Molecular Bases of Disease, Cell Biology, Histone acetyltransferase, Chromatin, Cell biology, 030104 developmental biology, Liver, biology.protein, Hepatocytes, Transcription Factors
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::62abd1289b726ecbca3f69a0e6e09c6d
https://pubmed.ncbi.nlm.nih.gov/31659122 -
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المؤلفون: Beat Müllhaupt, Mohammed Al-Suraih, Christian D. Fingas, Anja Moncsek, Gregory J. Gores, Camille Zuber, Patrick L. Splinter, Piero V. Valli, Joachim C. Mertens, James L. Kirkland, Eleonora Patsenker, Christy E. Trussoni, Yi Zhu, Achim Weber, Nicholas F. LaRusso, Steven P. O'Hara, Tamar Tchkonia
المساهمون: University of Zurich, Mertens, Joachim C
مصطلحات موضوعية: 0301 basic medicine, Small interfering RNA, Cell Survival, medicine.medical_treatment, Cholangitis, Sclerosing, Medizin, 610 Medicine & health, Bcl-xL, Article, Cholangiocyte, Mice, Random Allocation, 03 medical and health sciences, Reference Values, Fibrosis, 10049 Institute of Pathology and Molecular Pathology, medicine, Animals, Benzothiazoles, Molecular Targeted Therapy, Cells, Cultured, Cellular Senescence, Gene knockout, Cell Proliferation, Mice, Knockout, Platelet-Derived Growth Factor, Mice, Inbred BALB C, Hepatology, biology, Chemistry, Growth factor, Biopsy, Needle, Fibroblasts, Isoquinolines, medicine.disease, Immunohistochemistry, Drug Resistance, Multiple, 3. Good health, Disease Models, Animal, 10219 Clinic for Gastroenterology and Hepatology, 030104 developmental biology, Apoptosis, Cancer research, biology.protein, 2721 Hepatology, Bile Ducts, Platelet-derived growth factor receptor
وصف الملف: Moncsek_et_al-2018-Hepatology.pdf - application/pdf
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2885259d2f82cbdd368a8f438b4055cb
https://www.ncbi.nlm.nih.gov/pubmed/28802066 -
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المؤلفون: Gregory J. Gores, P. Vig, Steven P. O'Hara, Alexander Revzin, Maria Eugenia Guicciardi, Christy E. Trussoni, Yandong Gao, Maria J. Lorenzo Pisarello, Patrick L. Splinter, Nicholas F. LaRusso, Steven F. Bronk, Anuradha Krishnan
المصدر: Journal of hepatology. 69(3)
مصطلحات موضوعية: 0301 basic medicine, Liver Cirrhosis, CCR2, Receptors, CCR5, Receptors, CCR2, Cholangitis, Sclerosing, Article, Primary sclerosing cholangitis, Macrophage chemotaxis, 03 medical and health sciences, Liver disease, Mice, 0302 clinical medicine, Fibrosis, medicine, Macrophage, Animals, Chemokine CCL2, Liver injury, Hepatology, business.industry, Monocyte, Chemotaxis, Macrophages, Imidazoles, medicine.disease, Mice, Inbred C57BL, Disease Models, Animal, 030104 developmental biology, medicine.anatomical_structure, Treatment Outcome, Liver, Sulfoxides, Immunology, CCR5 Receptor Antagonists, 030211 gastroenterology & hepatology, business
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المؤلفون: Pamela S. Tietz, Lee R. Hagey, Taofic Mounajjed, James H. Tabibian, Steven P. O'Hara, Patrick L. Splinter, Nicholas F. LaRusso, Christy E. Trussoni
المصدر: Hepatology. 63:185-196
مصطلحات موضوعية: Male, 0301 basic medicine, Senescence, Pathology, medicine.medical_specialty, Cholangitis, Sclerosing, Biology, Cholangiocyte, Primary sclerosing cholangitis, Mice, 03 medical and health sciences, 0302 clinical medicine, Ductopenia, Fibrosis, medicine, Animals, Mice, Knockout, Hepatology, Hepatobiliary disease, medicine.disease, Ursodeoxycholic acid, Gastrointestinal Microbiome, Disease Models, Animal, 030104 developmental biology, Disease Progression, Alkaline phosphatase, Female, 030211 gastroenterology & hepatology, medicine.drug
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المؤلفون: Nicholas F. LaRusso, Patrick L. Splinter, Steven P. O'Hara, James H. Tabibian, Julie K. Heimbach, Christy E. Trussoni
المصدر: Laboratory investigation; a journal of technical methods and pathology
مصطلحات موضوعية: Male, Pathology, medicine.medical_specialty, Cholangitis, Sclerosing, Cell Separation, Biology, secretory phenotype, Article, Pathology and Forensic Medicine, Primary sclerosing cholangitis, Cell Line, Tumor, medicine, cellular senescence, Humans, Molecular Biology, digestive, oral, and skin physiology, epithelia, Cell Biology, Middle Aged, medicine.disease, Intercellular Junctions, Liver, next-generation sequencing, Female, cholestasis, Biomarkers
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المؤلفون: Beat Müllhaupt, Anja Moncsek, Achim Weber, Joachim C. Mertens, Steven P. O'Hara, Piero V. Valli, Patrick L. Splinter, Christian D. Fingas, Nicholas F. LaRusso, Eleonora Patsenker, C. Zuber
مصطلحات موضوعية: Pathology, medicine.medical_specialty, Bh3 mimetic, Stromal cell, Hepatology, business.industry, Fibrosis, Medizin, Medicine, business, medicine.disease
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e1adcb4b22b08f7bc3435bfc97bb6e72
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