يعرض 1 - 10 نتائج من 47 نتيجة بحث عن '"Patrick Twomey"', وقت الاستعلام: 1.01s تنقيح النتائج
  1. 1
    دورية أكاديمية
    Phase I Study of Safety and Pharmacokinetics of RO7297089, an Anti-BCMA/CD16a Bispecific Antibody, in Patients with Relapsed, Refractory Multiple Myeloma

    المؤلفون: Torben Plesner, Simon J. Harrison, Hang Quach, Cindy Lee, Adam Bryant, Annette Vangsted, Jane Estell, Michel Delforge, Fritz Offner, Patrick Twomey, Voleak Choeurng, Junyi Li, Robert Hendricks, Shannon M. Ruppert, Teiko Sumiyoshi, Karen Miller, Eunpi Cho, Fredrik Schjesvold

    المصدر: Clinical Hematology International, Vol 5, Iss 1, Pp 43-51 (2023)

    مصطلحات موضوعية: RO7297089, Multiple myeloma, BCMA, CD16a, Clinical trial, Diseases of the blood and blood-forming organs, RC633-647.5

    وصف الملف: electronic resource

    Relation: https://doaj.org/toc/2590-0048

    URL الوصول: https://doaj.org/article/1e942104b3254806bc7d60bb7973e0d7

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  2. 2
    دورية أكاديمية
    An open label study of the safety and efficacy of a single dose of weekly chloroquine and azithromycin administered for malaria prophylaxis in healthy adults challenged with 7G8 chloroquine-resistant Plasmodium falciparum in a controlled human malaria infection model

    المؤلفون: Jeffrey Livezey, Patrick Twomey, Meshell Morrison, Susan Cicatelli, Elizabeth H. Duncan, Melinda Hamer, Christine Lee, Jack Hutter, Kristin Mills, Jesse DeLuca, Lucas Poon, Daniel Selig, Chau Vuong, Jason Sousa, Thomas Oliver, Jason Bennett, James E. Moon, April Sikaffy, Martha Sedegah, Donna Tosh, Mara Kreishman-Deitrick, Paige Waterman

    المصدر: Malaria Journal, Vol 19, Iss 1, Pp 1-14 (2020)

    مصطلحات موضوعية: Malaria chemoprophylaxis, Azithromycin, Chloroquine, Controlled human malaria infection, Arctic medicine. Tropical medicine, RC955-962, Infectious and parasitic diseases, RC109-216

    وصف الملف: electronic resource

    Relation: http://link.springer.com/article/10.1186/s12936-020-03409-z; https://doaj.org/toc/1475-2875

    URL الوصول: https://doaj.org/article/ed1d3d6b98974024a5273f7695a18fba

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  3. 3
    دورية أكاديمية
    IMRAS-A clinical trial of mosquito-bite immunization with live, radiation-attenuated P. falciparum sporozoites: Impact of immunization parameters on protective efficacy and generation of a repository of immunologic reagents.

    المؤلفون: Bradley Hickey, Nimfa Teneza-Mora, Joanne Lumsden, Sharina Reyes, Martha Sedegah, Lindsey Garver, Michael R Hollingdale, Jo Glenna Banania, Harini Ganeshan, Megan Dowler, Anatalio Reyes, Cindy Tamminga, Alexandra Singer, Alicia Simmons, Maria Belmonte, Arnel Belmonte, Jun Huang, Sandra Inoue, Rachel Velasco, Steve Abot, Carlos S Vasquez, Ivelese Guzman, Mimi Wong, Patrick Twomey, Mariusz Wojnarski, James Moon, Yolanda Alcorta, Santina Maiolatesi, Michele Spring, Silas Davidson, Sidhartha Chaudhury, Eileen Villasante, Thomas L Richie, Judith E Epstein

    المصدر: PLoS ONE, Vol 15, Iss 6, p e0233840 (2020)

    مصطلحات موضوعية: Medicine, Science

    وصف الملف: electronic resource

    Relation: https://doaj.org/toc/1932-6203

    URL الوصول: https://doaj.org/article/09a1bfbcaf43443593836d98e5b0ffa5

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  4. 4
    Tiragolumab plus atezolizumab versus placebo plus atezolizumab as a first-line treatment for PD-L1-selected non-small-cell lung cancer (CITYSCAPE): primary and follow-up analyses of a randomised, double-blind, phase 2 study

    المؤلفون: Byoung Chul Cho, Delvys Rodriguez Abreu, Maen Hussein, Manuel Cobo, Anjan J Patel, Nevena Secen, Ki Hyeong Lee, Bartomeu Massuti, Sandrine Hiret, James Chih Hsin Yang, Fabrice Barlesi, Dae Ho Lee, Luis Paz Ares, Robert W Hsieh, Namrata S Patil, Patrick Twomey, Xiaoying Yang, Raymond Meng, Melissa L Johnson

    المصدر: The Lancet Oncology. 23:781-792

    مصطلحات موضوعية: Lung Neoplasms, Double-Blind Method, Oncology, Carcinoma, Non-Small-Cell Lung, Antineoplastic Combined Chemotherapy Protocols, Programmed Cell Death 1 Receptor, Antibodies, Monoclonal, Humans, Antineoplastic Agents, Antibodies, Monoclonal, Humanized, B7-H1 Antigen, Follow-Up Studies

    URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ddfdb6176761149b13cd86b947c07773
    https://doi.org/10.1016/s1470-2045(22)00226-1

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  5. 5
    Hypertriglyceridaemia: a commentary

    المؤلفون: Aidan Ryan, William G Simpson, Patrick Twomey

    المصدر: Journal of clinical pathology.

    مصطلحات موضوعية: General Medicine, Pathology and Forensic Medicine

    URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a4b50f7c4144eba93408a4529c6453c
    https://pubmed.ncbi.nlm.nih.gov/36167730

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  6. 6
    Personalized Cancer Vaccines: Clinical Landscape, Challenges, and Opportunities

    المؤلفون: Iraj Hosseini, Patrick Twomey, Colby S. Shemesh, Sandhya Girish, Anand Rotte, Joy C. Hsu, Ben-Quan Shen, Benjamin Wu

    المصدر: Mol Ther

    مصطلحات موضوعية: T-Lymphocytes, medicine.medical_treatment, Review, Bioinformatics, Cancer Vaccines, law.invention, 03 medical and health sciences, 0302 clinical medicine, Immune system, Drug Development, Cancer immunotherapy, Antigens, Neoplasm, law, Neoplasms, Drug Discovery, Biomarkers, Tumor, Genetics, medicine, Humans, Dosing, Precision Medicine, Molecular Biology, 030304 developmental biology, Pharmacology, Clinical Trials as Topic, 0303 health sciences, Clinical pharmacology, business.industry, Cancer, Dendritic Cells, medicine.disease, Clinical trial, Drug development, 030220 oncology & carcinogenesis, Molecular Medicine, Immunotherapy, business, Adjuvant

    URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b984660666735d33ee48d99dccec7dc
    https://doi.org/10.1016/j.ymthe.2020.09.038

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  7. 7
    Determination of Cytochrome P450 Isoenzyme 2D6 (CYP2D6) Genotypes and Pharmacogenomic Impact on Primaquine Metabolism in an Active-Duty US Military Population

    المؤلفون: William F. McCarthy, Donna Tosh, Kristopher M Paolino, Meshell N Morrison, James E Moon, Sean R Marcsisin, Jason W. Bennett, Christian A Darko, Qigui Li, Patrick Twomey, Philip L Smith, Brittney M Potter, Gregory A Reichard, Susan B Cicatelli, Brandon S Pybus, Kristin T Mills, Jeffrey W Froude, Thomas G Oliver, Michele D. Spring, Norman C. Waters, Jason C Sousa

    المصدر: The Journal of Infectious Diseases

    مصطلحات موضوعية: 0301 basic medicine, CYP2D6, Primaquine, phenotype, genotype, Metabolite, 030231 tropical medicine, Population, Pharmacology, Major Articles and Brief Reports, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Pharmacokinetics, Genotype, medicine, Immunology and Allergy, Parasites, education, military, Active metabolite, education.field_of_study, business.industry, 5,6-ortho-quinone, Phenotype, 030104 developmental biology, Infectious Diseases, chemistry, business, pharmacokinetics, metabolism, medicine.drug

    URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ab00d588e72cbdb11445682b8480461c
    https://doi.org/10.1093/infdis/jiz386

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  8. 8
    Pharmacokinetics of Ipatasertib in Subjects With Hepatic Impairment Using 2 Methods of Classification of Hepatic Function

    المؤلفون: Dhruvitkumar S Sutaria, Vikram Malhi, Christopher Craggs, Eunpi Cho, Rucha Sane, Jianshuang Wang, Adam Harris, Patrick Twomey, Luna Musib

    المصدر: Journal of clinical pharmacology. 62(2)

    مصطلحات موضوعية: Adult, Male, medicine.medical_specialty, Metabolic Clearance Rate, Metabolite, Antineoplastic Agents, Gastroenterology, Piperazines, Hepatic function, chemistry.chemical_compound, Pharmacokinetics, Internal medicine, Medicine, Humans, Pharmacology (medical), Aged, Pharmacology, Group study, Dose-Response Relationship, Drug, business.industry, Hepatic impairment, Healthy subjects, Patient Acuity, Cancer, Middle Aged, medicine.disease, Pyrimidines, chemistry, Area Under Curve, Dose reduction, Female, business, Liver Failure, Half-Life

    URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ab88201fbfe34eff771acac8b77d9b5
    https://pubmed.ncbi.nlm.nih.gov/34402068

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  9. 9
    A Phase I Study of RO7297089, a B-Cell Maturation Antigen (BCMA)-CD16a Bispecific Antibody in Patients with Relapsed/Refractory Multiple Myeloma (RRMM)

    المؤلفون: Junyi Li, Cindy Lee, Voleak Choeurng, Adam Bryant, Michel Delforge, Annette Juul Vangsted, Fritz Offner, Eunpi Choi, Karen Miller, Teiko Sumiyoshi, Hang Quach, Fredrik Schjesvold, Patrick Twomey, Robert Hendricks, Jane Estell, Simon J. Harrison, Torben Plesner

    المصدر: Plesner, T, Harrison, S J, Quach, H, Lee, C H, Bryant, A, Vangsted, A J, Estell, J, Delforge, M, Offner, F, Twomey, P, Choeurng, V, Li, J, Hendricks, R, Sumiyoshi, T, Miller, K, Choi, E & Schjesvold, F H 2021, ' A Phase I Study of RO7297089, a B-Cell Maturation Antigen (BCMA)-CD16a Bispecific Antibody in Patients with Relapsed/Refractory Multiple Myeloma (RRMM) ', Blood, vol. 138, no. Suppl. 1, 2755 . https://doi.org/10.1182/blood-2021-147418

    مصطلحات موضوعية: Bispecific antibody, business.industry, B-Cell Maturation Antigen, education, Immunology, Cell Biology, Hematology, medicine.disease, Biochemistry, Phase i study, Relapsed refractory, medicine, Cancer research, In patient, business, health care economics and organizations, Multiple myeloma

    URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::457c202e421dd889584fc81db341dedf
    https://doi.org/10.1182/blood-2021-147418

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  10. 10
    Abstract CT302: Phase Ia/Ib dose-escalation study of the anti-TIGIT antibody tiragolumab as a single agent and in combination with atezolizumab in patients with advanced solid tumors

    المؤلفون: Johanna C. Bendell, Philippe Bedard, Yung-Jue Bang, Patricia LoRusso, Stephen Hodi, Michael Gordon, Sandra D'Angelo, Jayesh Desai, Elena Garralda, Antoine Italiano, Myung-Ju Ahn, Andres Cervantes, Zev Wainberg, Emiliano Calvo, Marta Gil-Martin, Maria Martinez-Garcia, Rastilav Bahleda, Philippe Cassier, Jean-Pierre Delord, Amy Prawira, Ignacio Melero, Leisha Emens, Emanuela Romano, Karen Miller, Robert W. Hsieh, Cloris Xue, Kari Morrissey, Patrick Twomey, Kelly Gash, Namrata S. Patil, Jane Grogan, Raymond Meng, Byoung Cho, Tae Won Kim

    المصدر: Cancer Research. 80:CT302-CT302

    مصطلحات موضوعية: 0301 basic medicine, Oncology, Cancer Research, medicine.medical_specialty, biology, Anemia, business.industry, Cancer, medicine.disease, 03 medical and health sciences, 030104 developmental biology, 0302 clinical medicine, TIGIT, Tolerability, Pharmacokinetics, Atezolizumab, 030220 oncology & carcinogenesis, Pharmacodynamics, Internal medicine, biology.protein, medicine, Antibody, business

    URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::db31a81666212efcd4b8e83e3dc853e8
    https://doi.org/10.1158/1538-7445.am2020-ct302

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