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1
المؤلفون: Chunli Huang, Paul D. Lira, Love Victoria Alexandria, Oliphant Theodore Lawrence, Leslie L. Sharp, Sharon A. Sokolowski, Simon Bergqvist, Amy C. Shen, Rohner Allison Karlyn, Timothy Scott Fisher, Sangita M. Baxi, Regis Doyonnas, Cris Kamperschroer
المصدر: Cancer Immunology, Immunotherapy. 61:1721-1733
مصطلحات موضوعية: Male, Agonist, Cancer Research, medicine.drug_class, T-Lymphocytes, medicine.medical_treatment, T cell, Immunology, Biology, Pharmacology, Antibodies, Monoclonal, Humanized, Lymphocyte Activation, Monoclonal antibody, Mice, Immune system, Cell Line, Tumor, medicine, Animals, Humans, Immunology and Allergy, Leukocyte proliferation, Cell Proliferation, CD137, NF-kappa B, Antibodies, Monoclonal, Immunotherapy, Xenograft Model Antitumor Assays, Macaca fascicularis, 4-1BB Ligand, Cytokine, medicine.anatomical_structure, Oncology, Immunoglobulin G, Leukocytes, Mononuclear, Female
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2
المؤلفون: Donald M. Engelman, Paul D. Lira, Erin E. Matthews, Damien Thévenin, Lisa Gotow, Lawrence A. Reiter, William H. Brissette, Julia M. Rogers
المصدر: The FASEB Journal. 25:2234-2244
مصطلحات موضوعية: Models, Molecular, Rotation, Protein Conformation, Stereochemistry, Molecular Sequence Data, Allosteric regulation, Biochemistry, Protein Structure, Secondary, Research Communications, Allosteric Regulation, Piperidines, Genetics, medicine, Humans, Computer Simulation, Amino Acid Sequence, Receptor, Molecular Biology, Thrombopoietin receptor, Molecular Structure, Chemistry, Cytokine Receptor Activation, Ligand (biochemistry), Protein Structure, Tertiary, Transmembrane domain, Mechanism of action, Mutation, Biophysics, Protein Multimerization, medicine.symptom, Cytokine receptor, Receptors, Thrombopoietin, Biotechnology
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3
المؤلفون: Paul A. Rejto, James S. Hardwick, Jadwiga Bienkowska, Kai Wang, Thomas O’Brien, Mark Ozeck, Donghui Huang, Keith A. Ching, Geoffrey Chan, Jingjin Gao, Paul D. Lira
المصدر: Cancer Research. 78:LB-215
مصطلحات موضوعية: Neuroblastoma RAS viral oncogene homolog, Cancer Research, NPM1, Mutation, business.industry, Cancer, Myeloid leukemia, Context (language use), medicine.disease_cause, medicine.disease, Oncology, medicine, Cytarabine, Cancer research, KRAS, business, medicine.drug
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::f76ee72064819f53fe0514b220bd57a8
https://doi.org/10.1158/1538-7445.am2018-lb-215 -
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المؤلفون: David G. Perregaux, Timothy Scott Fisher, William H. Brissette, Paul D. Lira, Jeffrey L. Stock, Baiyong Li, Terence R.S. Ozolinš
المصدر: Biochemical and Biophysical Research Communications. 388:683-688
مصطلحات موضوعية: medicine.medical_specialty, Egl Nine Homolog 1, Procollagen-Proline Dioxygenase, Biophysics, Mice, Transgenic, Biochemistry, Cell Line, Dioxygenases, Hypoxia-Inducible Factor-Proline Dioxygenases, Mixed Function Oxygenases, Mice, chemistry.chemical_compound, In vivo, RNA interference, Internal medicine, medicine, Animals, Humans, Erythropoiesis, RNA, Small Interfering, Erythropoietin, Molecular Biology, biology, Nuclear Proteins, Cell Biology, Cell biology, Repressor Proteins, Vascular endothelial growth factor, Endocrinology, chemistry, Cell culture, biology.protein, RNA Interference, EGLN1, medicine.drug
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5
المؤلفون: James H. Roache, Eric B. McElroy, Timothy Joseph Paradis, Aikomari Guzman-Martinez, Sara A. Burrell, Robert S. Foti, Matthew Frank Brown, Greg D. Lundquist, Kevin B. Bahnck, James P. Driscoll, Andrei Shavnya, Laurie Tylaska, Ronald P. Gladue, Michael B. Fisher, Poss Christopher Stanley, Molly A. McGlynn, William H. Brissette, Yi Lu, Brett M. Lillie, Laura Cook Blumberg, Flavia Fedeles, Matthew Merrill Hayward, Richard M. Shepard, Kristen A. Trevena, Paul D. Lira
المصدر: Bioorganic & Medicinal Chemistry Letters. 17:3109-3112
مصطلحات موضوعية: CCR1, Human liver, Chemistry, Organic Chemistry, Clinical Biochemistry, Receptors, CCR1, Antagonist, Pharmaceutical Science, Biological activity, Haplorhini, Biochemistry, Chemical synthesis, Piperazines, Rats, Dogs, Pharmacokinetics, Drug Discovery, Microsomes, Liver, Microsome, Animals, Humans, Molecular Medicine, Receptors, Chemokine, Molecular Biology
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6
المؤلفون: Matthew Frank Brown, William H. Brissette, Amy P DiRico, Eric B. McElroy, Ronald P. Gladue, Timothy Joseph Paradis, Laurie Tylaska, Maryrose J. Conklyn, Deye Zheng, Erin N Mairs, John Charles Kath, Poss Christopher Stanley, Molly A. McGlynn, Dorff Peter H, William H. Martin, Brett M. Lillie, Ingrid A. Stock, Paul D. Lira
المصدر: Bioorganic & Medicinal Chemistry Letters. 14:2169-2173
مصطلحات موضوعية: CCR1, medicine.drug_class, Chemistry, Stereochemistry, Organic Chemistry, Clinical Biochemistry, Receptors, CCR1, Pharmaceutical Science, Carboxamide, Biochemistry, Small molecule, In vitro, Cell Line, Structure-Activity Relationship, Drug Discovery, Lead structure, medicine, Humans, Molecular Medicine, Structure–activity relationship, Receptors, Chemokine, Molecular Biology
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7
المؤلفون: Mary M. Payette, Laurent P. Audoly, Joan R. Wicks, William H. Brissette, Sandra P. McCurdy, Christopher A. Gabel, Carol Donovan, Nina Petrushova, Jeffrey M. Labasi, Paul D. Lira
المصدر: The Journal of Immunology. 168:6436-6445
مصطلحات موضوعية: Lipopolysaccharides, Male, medicine.medical_specialty, T-Lymphocytes, medicine.medical_treatment, Immunology, Arthritis, Monocytes, Leukocyte Count, Mice, Adenosine Triphosphate, In vivo, Internal medicine, medicine, Extracellular, Animals, Immunology and Allergy, L-Selectin, Receptor, Collagen Type II, Cells, Cultured, Inflammation, Mice, Knockout, B-Lymphocytes, biology, Receptors, Purinergic P2, Antibodies, Monoclonal, medicine.disease, Arthritis, Experimental, Mice, Inbred C57BL, Cytokine, Endocrinology, Proteoglycan, Mice, Inbred DBA, Monoclonal, Leukocytes, Mononuclear, Macrophages, Peritoneal, biology.protein, Female, Receptors, Purinergic P2X7, Antibody, Injections, Intraperitoneal, Interleukin-1
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1eddf8293d627fc6d39ff314af7b7c8d
https://doi.org/10.4049/jimmunol.168.12.6436 -
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المؤلفون: Gianni Medoro, Ana Paula Galvão Da Silva, Farideh Z. Bischoff, Paul D. Lira, Nicolò Manaresi, Jennifer Chow
المصدر: Journal of Clinical Oncology. 35:e23089-e23089
مصطلحات موضوعية: Cancer Research, Oncology, Tumor-infiltrating lymphocytes, business.industry, Gene expression, Cancer research, Medicine, Cancer, Mouse tissue, Differential diagnosis, business, medicine.disease
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::b57330556f910917e1c86dcaedb01a6f
https://doi.org/10.1200/jco.2017.35.15_suppl.e23089 -
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المؤلفون: Lynn M. Hames, Ranjeny Thomas, Robin T. Nelson, William H. Brissette, Lisa S. Hayes, Ronald P. Gladue, Paul D. Lira, Ann C. Cunningham, Shaun R. McColl, James G. Boyd, Timothy Joseph Paradis, Kuldeep S. Neote
المصدر: Genomics. 73:28-37
مصطلحات موضوعية: Receptors, CCR6, Signal peptide, T-Lymphocytes, Molecular Sequence Data, chemical and pharmacologic phenomena, Biology, Exon, Genetics, Humans, splice, Cloning, Molecular, In Situ Hybridization, Fluorescence, Chemokine CCL20, Base Sequence, Chromosome localization, Intron, Chromosome Mapping, hemic and immune systems, DNA, Exons, Macrophage Inflammatory Proteins, respiratory system, Beta Chemokine, Molecular biology, Introns, CCL20, Alternative Splicing, Chemokines, CC, Chromosomes, Human, Pair 2, Calcium, Receptors, Chemokine, CD8
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10
المؤلفون: Lilli Ann Wolf-Gouveia, Paul D. Lira, Eric B. McElroy, Lisa Marie Thomasco, Matthew Frank Brown, Christopher S. Jones, Jonathan L. Doty, Lawrence A. Reiter, Sandra P. McCurdy, Anthony Marfat, Sharon L. Ripp, Mark J. Mitton-Fry, William H. Brissette, Andrei Shavnya, Linde Robert Gerald, Thomas M. Harris, Kristen A. Trevena, Qifang Li, Laura Cook Blumberg, Amy S. Antipas, James P. Driscoll, Michael John Munchhof, Jeffrey M. Casavant
المصدر: Bioorganic & Medicinal Chemistry Letters. 19:1428-1430
مصطلحات موضوعية: Agonist, Pyrimidine, medicine.drug_class, Clinical Biochemistry, Administration, Oral, Biological Availability, Pharmaceutical Science, Pharmacology, Benzoates, Biochemistry, chemistry.chemical_compound, Piperidines, Pharmacokinetics, In vivo, Drug Discovery, medicine, Animals, Humans, Moiety, Benzamide, Molecular Biology, Thrombopoietin, Organic Chemistry, Pyrazinamide, Rats, Bioavailability, Hydrazines, Pyrimidines, chemistry, Pyrazoles, Molecular Medicine, Caco-2 Cells, Receptors, Thrombopoietin