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المؤلفون: Tom G. Mastenbroek, Renhao Li, Paul E. Bock, Marjo M. P. C. Donners, Peter William Collins, Constance C.F.M.J. Baaten, Tomasz Misztal, Paola E. J. van der Meijden, Marion A.H. Feijge, Frauke Swieringa, Johan W. M. Heemskerk
المساهمون: Biochemie, RS: CARIM - R1.03 - Cell biochemistry of thrombosis and haemostasis, Pathologie, RS: CARIM - R3.06 - The vulnerable plaque: makers and markers, RS: CARIM - R1.04 - Clinical thrombosis and haemostasis
المصدر: Blood advances, 2(18), 2320-2331. The American Society of Hematology
مصطلحات موضوعية: 0301 basic medicine, Blood Platelets, PHOSPHATIDYLSERINE EXPOSURE, MECHANISM, HEMOSTATIC FUNCTION, ADAM10, Platelet Membrane Glycoproteins, 030204 cardiovascular system & hematology, Thrombosis and Hemostasis, 03 medical and health sciences, 0302 clinical medicine, Thrombin, Scott syndrome, medicine, Disintegrin, Humans, Platelet, Platelet activation, Protein kinase C, IN-VIVO, Glycoproteins, ADAM17, biology, Chemistry, CLEAVAGE, Ionomycin, SCOTT SYNDROME, Thrombosis, Hematology, medicine.disease, Flow Cytometry, Platelet Activation, Cell biology, FIBRIN, carbohydrates (lipids), THROMBUS FORMATION, ADAM Proteins, 030104 developmental biology, Platelet Glycoprotein GPIb-IX Complex, Caspases, biology.protein, Calcium, METALLOPROTEINASE, GPVI, Biomarkers, medicine.drug, Signal Transduction
وصف الملف: application/pdf
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المؤلفون: Gabriel Courties, Jazz Munitz, Matthias Nahrendorf, Giuseppe Carlucci, D. Michael Tillson, Edmund J. Keliher, Filip K. Swirski, Gregory R. Wojtkiewicz, Yoshiko Iwamoto, Marvin Krohn-Grimberghe, Sharron Barney, Paul H. Walz, Willem J. M. Mulder, Mandy M. T. van Leent, Charlotte G. Muse, Kay P. Riddell, William R. Church, Yohana C. Toner, Georgios Soultanidis, Anu E. Meerwaldt, Vanessa Frodermann, Glenn Horne, Claudia Calcagno, Jana Grune, Yu Xiang Ye, Paul E. Bock, Ashoka Maddur-Appajaiah, Peter Panizzi, Kaitlyn Bushey, Alexander Maier, Ingrid M. Verhamme, Carlos Pérez-Medina, Yuan Sun, Brian Anderson
المساهمون: Precision Medicine, ICMS Core, Amsterdam Cardiovascular Sciences, ACS - Atherosclerosis & ischemic syndromes, Graduate School, AII - Infectious diseases
المصدر: Science Translational Medicine, 12(568):eaay2104. American Association for the Advancement of Science (AAAS)
Science translational medicine, 12(568):eaay2104. American Association for the Advancement of Scienceمصطلحات موضوعية: 0301 basic medicine, Innate immune system, business.industry, medicine.drug_class, medicine.medical_treatment, Antibiotics, General Medicine, Immunotherapy, 030204 cardiovascular system & hematology, medicine.disease_cause, medicine.disease, SDG 3 – Goede gezondheid en welzijn, Staphylocoagulase, Microbiology, 03 medical and health sciences, 030104 developmental biology, 0302 clinical medicine, Immune system, SDG 3 - Good Health and Well-being, Staphylococcus aureus, Medicine, Endocarditis, business, Preclinical imaging
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d928326fbd0cfdf4b4862a8abcc53a82
https://research.tue.nl/nl/publications/2eac6af2-5267-40f7-97d7-c6b3f6a2aebb -
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المؤلفون: Markus Voehler, Ingrid M. Verhamme, Peter Panizzi, Jens Meiler, Paul E. Bock, Ashoka A. Maddur
المصدر: The Journal of Biological Chemistry
مصطلحات موضوعية: Circular dichroism, NMR titration, ProT, prothrombin, me, mol-equivalent, Peptide, Biochemistry, Efb, extracellular Fbg-binding protein, fibrin, T, thrombin, chemistry.chemical_classification, Alanine, Fbg, fibrinogen, SC, staphylocoagulase, HSQC, heteronuclear single quantum coherence, Fluorescence, fluorescence equilibrium binding, endocarditis, Research Article, Protein Binding, Coagulase, Staphylococcus aureus, native PAGE, FPR-CK, D-Phe-Pro-Arg-chloromethyl ketone, Stereochemistry, R1 to R7, repeat 1 to 7, SC(1–660), full-length SC, TEV, tobacco etch virus, Ala, alanine, Bacterial Proteins, Fbn, fibrin, Molecule, 5-IAF, 5-iodoacetamidofluorescein, coagulation, Binding site, Molecular Biology, staphylocoagulase, prothrombin, Binding Sites, GPRP, Gly-Pro-Arg-Pro, PR, pseudorepeat, Terminal Repeat Sequences, Fibrinogen, Fibrinogen binding, Cell Biology, Mr, relative molecular mass, 5F, 5-fluorescein, Staphylocoagulase, Affinities, MP, minimal peptide, chemistry, FFR-CK, D-Phe-Phe-Arg-chloromethyl ketone, frag D, fibrinogen fragment D
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ab434dab6c5878051d74b0cc5b98be2
https://doi.org/10.1016/j.jbc.2021.101493 -
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المؤلفون: Ashoka A. Maddur, Breanne H.Y. Gibson, Mary E. Aschenbrenner, Peter Panizzi, Paul E. Bock, Jonathan H. Sheehan, Ingrid M. Verhamme, Jens Meiler, Heather K. Kroh
المصدر: J Biol Chem
مصطلحات موضوعية: 0301 basic medicine, Coagulase, Models, Molecular, Staphylococcus aureus, Stereochemistry, Allosteric regulation, Ligand Binding Protein, Cleavage (embryo), Biochemistry, Substrate Specificity, 03 medical and health sciences, chemistry.chemical_compound, Thrombin, Bacterial Proteins, Prothrombinase, medicine, Humans, natural sciences, Molecular Biology, Dipeptide, Binding Sites, 030102 biochemistry & molecular biology, Chemistry, Cell Biology, Staphylococcal Infections, Staphylocoagulase, 030104 developmental biology, Zymogen activation, Enzymology, Prothrombin, medicine.drug, Protein Binding
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::784daea48caa6095f991ef564fa9bf71
https://pubmed.ncbi.nlm.nih.gov/32156702 -
5دورية أكاديمية
المؤلفون: Michelle A Berny, Imke C A Munnix, Jocelyn M Auger, Saskia E M Schols, Judith M E M Cosemans, Peter Panizzi, Paul E Bock, Steve P Watson, Owen J T McCarty, Johan W M Heemskerk
المصدر: PLoS ONE, Vol 5, Iss 4, p e10415 (2010)
وصف الملف: electronic resource
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المؤلفون: Peter, Panizzi, Marvin, Krohn-Grimberghe, Edmund, Keliher, Yu-Xiang, Ye, Jana, Grune, Vanessa, Frodermann, Yuan, Sun, Charlotte G, Muse, Kaitlyn, Bushey, Yoshiko, Iwamoto, Mandy M T, van Leent, Anu, Meerwaldt, Yohana C, Toner, Jazz, Munitz, Alexander, Maier, Georgios, Soultanidis, Claudia, Calcagno, Carlos, Pérez-Medina, Giuseppe, Carlucci, Kay P, Riddell, Sharron, Barney, Glenn, Horne, Brian, Anderson, Ashoka, Maddur-Appajaiah, Ingrid M, Verhamme, Paul E, Bock, Gregory R, Wojtkiewicz, Gabriel, Courties, Filip K, Swirski, William R, Church, Paul H, Walz, D Michael, Tillson, Willem J M, Mulder, Matthias, Nahrendorf
المصدر: Sci Transl Med
مصطلحات موضوعية: Coagulase, Mice, Staphylococcus aureus, Swine, Animals, Endocarditis, Bacterial, Staphylococcal Infections, Multimodal Imaging, Article
URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid________::920a3adeca48dfa0665b54c040d71ed2
https://pubmed.ncbi.nlm.nih.gov/33148623 -
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المؤلفون: Heather K. Kroh, Paul E. Bock, Xin Huang, Richard Swanson
المصدر: J Biol Chem
مصطلحات موضوعية: 0301 basic medicine, medicine.medical_treatment, Protein Z, Mutation, Missense, Serpin, Biochemistry, Cofactor, Antibodies, 03 medical and health sciences, Prothrombinase, medicine, Humans, Molecular Biology, Blood Coagulation, Serpins, Protease, 030102 biochemistry & molecular biology, biology, Chemistry, Thrombin, Factor V, Cell Biology, Protease inhibitor (biology), Kinetics, 030104 developmental biology, Coagulation, Amino Acid Substitution, Factor Xa, biology.protein, Biophysics, Enzymology, Prothrombin, Protein C, medicine.drug
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b1cd9a1b9c0bac7203997bf4d44069fe
https://europepmc.org/articles/PMC6514612/ -
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المؤلفون: Peter Panizzi, Paul E. Bock, Matthias Nahrendorf, Heather Eggleston, Richard Davis, Tiffany A. Peterson, Frances Johnson
المصدر: Molecular Imaging and Biology. 17:793-801
مصطلحات موضوعية: Cancer Research, Streptococcus pyogenes, Plasmin, Streptokinase, Biology, medicine.disease_cause, Article, Microbiology, Sepsis, Mice, In vivo, Streptococcal Infections, medicine, Animals, Bioluminescence, Bioluminescence imaging, Radiology, Nuclear Medicine and imaging, Pathogen, Skin, medicine.disease, Mice, Inbred C57BL, Disease Models, Animal, Oncology, Immunology, medicine.drug
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المؤلفون: Paul E. Bock, Ingrid M. Verhamme
المصدر: Journal of Biological Chemistry. 289:28006-28018
مصطلحات موضوعية: Protein Conformation, Catalytic complex, Stereochemistry, Plasmin, medicine.medical_treatment, Amino Acid Motifs, Plasma protein binding, Biochemistry, Benzamidine, Substrate Specificity, chemistry.chemical_compound, Protein structure, Bacterial Proteins, Streptococcal Infections, Zymogen, medicine, Humans, Streptokinase, Fibrinolysin, Binding site, Molecular Biology, Binding Sites, Protease, Chemistry, Streptococcus, Plasminogen, Cell Biology, Kinetics, Enzymology, Biocatalysis, circulatory and respiratory physiology, Protein Binding, medicine.drug
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c83cf7297ec1fcd49075ab436621d1bd
https://doi.org/10.1074/jbc.m114.589077 -
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المؤلفون: Markus Voehler, Jens Meiler, Paul E. Bock, Maddur Appajaiah Ashoka
المصدر: Biomolecular NMR assignments. 11(2)
مصطلحات موضوعية: 0301 basic medicine, Coagulase, Staphylococcus aureus, Stereochemistry, chemistry.chemical_element, Sequence (biology), 010402 general chemistry, 01 natural sciences, Biochemistry, Article, 03 medical and health sciences, chemistry.chemical_compound, Residue (chemistry), Nuclear magnetic resonance, Structural Biology, Amide, Nuclear Magnetic Resonance, Biomolecular, Staphylocoagulase, Amides, Protein tertiary structure, Carbon, 0104 chemical sciences, 030104 developmental biology, chemistry, Assignment methods, Heteronuclear single quantum coherence spectroscopy