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المؤلفون: Muthusamy Venkatraj, Pieter Van der Veken, Jan Heeres, Guy Caljon, Koen Augustyns, Jurgen Joossens, Louis Maes, Paul J. Lewi, Irene G. Salado
المصدر: European journal of medicinal chemistry
مصطلحات موضوعية: 0301 basic medicine, Male, Trypanosoma brucei rhodesiense, Cell Survival, Phenotypic screening, Trypanosoma cruzi, Trypanosoma brucei brucei, Antiprotozoal Agents, Pharmacology, Trypanosoma brucei, 01 natural sciences, 03 medical and health sciences, chemistry.chemical_compound, Mice, Structure-Activity Relationship, Usually fatal, Drug Discovery, medicine, Animals, Humans, African trypanosomiasis, Leishmania infantum, Biology, Triazine, Cell Proliferation, biology, Dose-Response Relationship, Drug, Molecular Structure, 010405 organic chemistry, Triazines, Pharmacology. Therapy, Organic Chemistry, Tsetse fly, General Medicine, Fibroblasts, medicine.disease, biology.organism_classification, Reverse transcriptase, 3. Good health, 0104 chemical sciences, 030104 developmental biology, chemistry, Reverse Transcriptase Inhibitors, Human medicine, Glossina
, Dimerization وصف الملف: pdf
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المؤلفون: Pieter Van der Veken, Kevin K. Ariën, Koen Augustyns, Guido Vanham, Paul Cos, Bertrand Dirié, Jan Heeres, Paul J. Lewi, Muthusamy Venkatraj, Johan Michiels, Louis Maes, Jurgen Joossens, Sophie Lyssens
المصدر: Bioorganic and medicinal chemistry
مصطلحات موضوعية: Trypanosoma brucei rhodesiense, Pyrimidine, Anti-HIV Agents, Cell Survival, Trypanosoma brucei brucei, Clinical Biochemistry, Pharmaceutical Science, Microbial Sensitivity Tests, Biochemistry, Cell Line, Nucleoside Reverse Transcriptase Inhibitor, Structure-Activity Relationship, chemistry.chemical_compound, Parasitic Sensitivity Tests, In vivo, Drug Discovery, Humans, Structure–activity relationship, Biology, Molecular Biology, Triazine, Dose-Response Relationship, Drug, Molecular Structure, Chemistry, Pharmacology. Therapy, Organic Chemistry, Trypanocidal Agents, HIV Reverse Transcriptase, In vitro, Reverse transcriptase, 3. Good health, HIV-1, Reverse Transcriptase Inhibitors, Molecular Medicine, Nucleoside
وصف الملف: pdf
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المؤلفون: Johan Michiels, Sergey Sergeyev, Paul J. Lewi, Philippe Franck, Guido Vanham, Jan Heeres, Kevin K. Ariën, Christophe M. L. Vande Velde, Ashok K. Yadav, Bert U. W. Maes, Hans De Winter
المصدر: Journal of medicinal chemistry
مصطلحات موضوعية: 0301 basic medicine, Pyrimidine, Anti-HIV Agents, Pyridines, Stereochemistry, Mutant, Human immunodeficiency virus (HIV), Nanotechnology, Microbial Sensitivity Tests, medicine.disease_cause, 01 natural sciences, Cell Line, Nucleoside Reverse Transcriptase Inhibitor, Structure-Activity Relationship, 03 medical and health sciences, chemistry.chemical_compound, Drug Discovery, medicine, Humans, Moiety, Structure–activity relationship, Aniline Compounds, Dose-Response Relationship, Drug, Molecular Structure, 010405 organic chemistry, Chemistry, Pharmacology. Therapy, HIV Reverse Transcriptase, Reverse transcriptase, In vitro, 0104 chemical sciences, Fluorobenzenes, 030104 developmental biology, HIV-1, Reverse Transcriptase Inhibitors, Molecular Medicine
وصف الملف: pdf
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المؤلفون: Frans Awouters, Paul J. Lewi
المصدر: Arzneimittelforschung. 57:625-632
مصطلحات موضوعية: medicine.medical_specialty, medicine.drug_class, Atypical antipsychotic, History, 21st Century, Structure-Activity Relationship, Pimozide, Paliperidone Palmitate, Drug Discovery, medicine, Haloperidol, Humans, Paliperidone, Psychiatry, Fluspirilene, Risperidone, business.industry, Isoxazoles, Dopamine receptor binding, History, 20th Century, Pyrimidines, Psychotic Disorders, business, Antipsychotic Agents, medicine.drug
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::40ab34dc85092ceed20f655a575d68e3
https://doi.org/10.1055/s-0031-1296660 -
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المؤلفون: Kalyan Das, Stephen H. Hughes, Joseph D. Bauman, Eddy Arnold, Aaron J. Shatkin, Arthur D. Clark, Yulia Volovik Frenkel, Paul J. Lewi
المصدر: Proceedings of the National Academy of Sciences. 105:1466-1471
مصطلحات موضوعية: Anti-HIV Agents, Protein Conformation, Stereochemistry, Amino Acid Motifs, Molecular Sequence Data, Mutant, Crystallography, X-Ray, Protein Engineering, chemistry.chemical_compound, Protein structure, Drug Resistance, Viral, Nitriles, Hydrolase, medicine, Humans, Amino Acid Sequence, Enzyme Inhibitors, Polymerase, Diarylpyrimidines, Multidisciplinary, biology, Reverse-transcriptase inhibitor, Rilpivirine, virus diseases, Protein engineering, Biological Sciences, HIV Reverse Transcriptase, Reverse transcriptase, Pyrimidines, chemistry, Drug Design, Mutation, biology.protein, Reverse Transcriptase Inhibitors, medicine.drug
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8aa57915624591a92123627a301a2113
https://doi.org/10.1073/pnas.0711209105 -
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المؤلفون: Manuel Morrens, Wouter Hulstijn, Paul J. Lewi, Bernard Sabbe
المصدر: Psychiatry research
Psychiatry Research, 161, 1, pp. 121-125
Psychiatry Research, 161, 121-125مصطلحات موضوعية: Adult, Male, Nosology, medicine.medical_specialty, Psychosis, Catatonia, Neuropsychological Tests, behavioral disciplines and activities, Diagnosis, Differential, Discrimination Learning, Reaction Time, medicine, Humans, Psychiatry, Biological Psychiatry, Psychomotor learning, Schizophrenia, Catatonic, Action, intention, and motor control, Perception, Action and Control [DI-BCB_DCC_Theme 2], Cognition, medicine.disease, Psychiatry and Mental health, Stereotypy (non-human), Pattern Recognition, Visual, Schizophrenia, Female, Human medicine, Psychomotor Disorders, Stereotyped Behavior, Cognition Disorders, Psychomotor disorder, Psychology, Psychomotor Performance, psychological phenomena and processes, Antipsychotic Agents, Clinical psychology
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ae79b68d43f695ec6b2b9f215deb5a8
https://doi.org/10.1016/j .psychres.2008.01.017 -
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المؤلفون: Paul J. Lewi, Johanna Smeyers-Verbeke
المساهمون: Analytical Chemistry and Pharmaceutical Technology
المصدر: Journal of Chemometrics. 21:252-256
مصطلحات موضوعية: Work (electrical), Operations research, Computer science, Applied Mathematics, Perspective (graphical), Engineering ethics, Prof. D.L.Massart, Analytical Chemistry
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المؤلفون: Manuel Morrens, Wouter Hulstijn, Paul J. Lewi, Marc De Hert, Bernard Sabbe
المصدر: Schizophrenia Research, 84, 2/3, pp. 397-404
Schizophrenia research
Schizophrenia Research, 84, 397-404مصطلحات موضوعية: Adult, Male, medicine.medical_specialty, Perseveration, Stereotypic Movement Disorder, Neuropsychological Tests, Audiology, Severity of Illness Index, Developmental psychology, Wisconsin Card Sorting Test, medicine, Humans, Biological Psychiatry, California Verbal Learning Test, Action, intention, and motor control, Neuropsychology, Cognition, medicine.disease, Diagnostic and Statistical Manual of Mental Disorders, Stereotypic movement disorder, Psychiatry and Mental health, Stereotypy (non-human), Cognitive inhibition, Schizophrenia, Female, medicine.symptom, Cognition Disorders, Psychology
وصف الملف: application/pdf
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::61981e3b1c5879b838d4f53ffcf551e8
https://doi.org/10.1016/j .schres.2006.01.024 -
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المؤلفون: Paul J. Lewi, Eddy Arnold, Stephen H. Hughes, Kalyan Das
المصدر: Progress in Biophysics and Molecular Biology. 88:209-231
مصطلحات موضوعية: Gene Expression Regulation, Viral, Drug, Molecular model, Anti-HIV Agents, Protein Conformation, Stereochemistry, media_common.quotation_subject, Dapivirine, Biophysics, Etravirine, Biology, Structure-Activity Relationship, chemistry.chemical_compound, Drug Delivery Systems, Drug Resistance, Multiple, Viral, medicine, Animals, Humans, Molecular Biology, media_common, Diarylpyrimidines, Flexibility (engineering), Acquired Immunodeficiency Syndrome, Crystallography, Genetic Variation, virus diseases, Adaptation, Physiological, HIV Reverse Transcriptase, Reverse transcriptase, chemistry, Drug Design, HIV-1, Reverse Transcriptase Inhibitors, Nucleoside, medicine.drug
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6cc84498852bfc0bc6296de615be12bd
https://doi.org/10.1016/j .pbiomolbio.2004.07.001 -
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المؤلفون: Paul J. Lewi
المصدر: Journal of Chemometrics. 19:282-287
مصطلحات موضوعية: Scientific enterprise, Engineering, business.industry, Applied Mathematics, media_common.quotation_subject, Perspective (graphical), Foundation (evidence), Case description, Genius, Analytical Chemistry, Statistics, Charisma, business, media_common