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1دورية أكاديمية
المؤلفون: Nicky J. Willis, Elliott D. Bayle, George Papageorgiou, David Steadman, Benjamin N. Atkinson, William Mahy, Paul V. Fish
المصدر: Beilstein Journal of Organic Chemistry, Vol 15, Iss 1, Pp 2790-2797 (2019)
مصطلحات موضوعية: brain penetration, 1-chloro-1,2-benziodoxol-3-one, electrophilic chlorination, lp-922056, notum inhibitor, Science, Organic chemistry, QD241-441
وصف الملف: electronic resource
Relation: https://doaj.org/toc/1860-5397
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2
المؤلفون: Benjamin N. Atkinson, Nicky J. Willis, Yuguang Zhao, Chandni Patel, Sarah Frew, Kathryn Costelloe, Lorenza Magno, Fredrik Svensson, E. Yvonne Jones, Paul V. Fish
المصدر: European Journal of Medicinal Chemistry. 251:115132
مصطلحات موضوعية: Pharmacology, Organic Chemistry, Drug Discovery, General Medicine
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3
المؤلفون: Benjamin N, Atkinson, Nicky J, Willis, Jennifer, Smith, Rebecca, Gill, Jody, Ali, Zhou, Xu, Ping-Shan, Lai, Paul V, Fish
المصدر: RSC advances. 12(41)
URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid________::30181eb9e0169a716f6a66ed1cd3f3de
https://pubmed.ncbi.nlm.nih.gov/36275171 -
4
المؤلفون: Peter Loppnau, Minkui Luo, Pegah Ghiabi, Albina Bolotokova, Irene Chau, Fengling Li, Jing Liu, Matthieu Schapira, Karla J. F. Satchell, Sumera Perveen, Ke Wang, Aliakbar Khalili Yazdi, Paul V. Fish, Jian Jin, Peter Brown, Deyao Li, Masoud Vedadi, David Smil, Kanchan Devkota, Taraneh Hajian
المصدر: Slas Discovery
bioRxivمصطلحات موضوعية: RNA capping, Methyltransferase, coronavirus, Viral Nonstructural Proteins, medicine.disease_cause, Virus Replication, 01 natural sciences, Biochemistry, Antiviral Agents, Methylation, Virus, Article, Analytical Chemistry, 03 medical and health sciences, chemistry.chemical_compound, medicine, Humans, Binding site, Pandemics, 030304 developmental biology, Coronavirus, Original Research, 0303 health sciences, Binding Sites, SARS-CoV-2, RNA, COVID-19, Small molecule, 0104 chemical sciences, 010404 medicinal & biomolecular chemistry, chemistry, Exoribonucleases, nsp14, Molecular Medicine, RNA, Viral, DNA, Biotechnology, Protein Binding
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a55059fd32681033cafc1474270f7838
http://europepmc.org/articles/PMC8458670 -
5
المؤلفون: S Jolly, Paul V. Fish, E Y Jones, Yuguang Zhao, S Benvegnu
المصدر: Future Medicinal Chemistry
مصطلحات موضوعية: Models, Molecular, animal structures, High-throughput screening, Notum inhibitors, Computational biology, high-throughput screening, Small Molecule Libraries, 03 medical and health sciences, Carboxylesterase, 0302 clinical medicine, Drug Discovery, Humans, structural biology, Enzyme Inhibitors, Special Report, activity-based protein profiling, 030304 developmental biology, Pharmacology, 0303 health sciences, Virtual screening, Molecular Structure, fungi, Esterases, Wnt signaling pathway, Activity-based proteomics, fragment screening, virtual screening, hit-finding strategies, Wnt signaling, Small molecule, Notum, 3. Good health, Structural biology, 030220 oncology & carcinogenesis, Molecular Medicine
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6
المؤلفون: Benjamin N. Atkinson, Nicky J. Willis, Jennifer Smith, Rebecca Gill, Jody Ali, Zhou Xu, Ping-Shan Lai, Paul V. Fish
مصطلحات موضوعية: General Chemical Engineering, General Chemistry
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::faf0c4165b4fd2acdb0efbe7c2d45e04
https://doi.org/10.26434/chemrxiv-2022-4vzgh -
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المؤلفون: Benjamin N. Atkinson, Fredrik Svensson, Hannah Woodward, Paul Whiting, Elliott D. Bayle, Paul V. Fish, Nicky J. Willis, Jean-Paul Vincent, David Steadman
المصدر: Journal of Medicinal Chemistry
مصطلحات موضوعية: Cytoplasm, animal structures, Druggability, Molecular Dynamics Simulation, 01 natural sciences, Negative regulator, Small Molecule Libraries, 03 medical and health sciences, Carboxylesterase, Catalytic Domain, Drug Discovery, Humans, Enzyme Inhibitors, Wnt Signaling Pathway, 030304 developmental biology, Cell Nucleus, 0303 health sciences, Binding Sites, Carboxylesterase activity, Chemistry, fungi, Esterases, Wnt signaling pathway, Small molecule, Notum, 0104 chemical sciences, Cell biology, 010404 medicinal & biomolecular chemistry, Perspective, embryonic structures, Molecular Medicine
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8
المصدر: Slas Discovery
مصطلحات موضوعية: Drug Evaluation, Preclinical, 010402 general chemistry, Machine learning, computer.software_genre, 01 natural sciences, Biochemistry, Analytical Chemistry, Machine Learning, Small Molecule Libraries, 03 medical and health sciences, Resource (project management), Drug Discovery, Original Research, 030304 developmental biology, 0303 health sciences, business.industry, iterative screening, High-Throughput Screening Assays, 0104 chemical sciences, AI, Molecular Medicine, HTS, Artificial intelligence, business, computer, PubChem, Biotechnology
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::72a46567ea7b830c56425924f8d9cce1
https://doi.org/10.1177/2472555220949495 -
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المؤلفون: Amy Monaghan, Paul Whiting, James Hillier, Svend Kjaer, Reinis R. Ruza, Jean-Paul Vincent, S. Frew, Paul V. Fish, L. Vecchia, William Mahy, James Sipthorp, Fredrik Svensson, Nicky J. Willis, Magda Bictash, Hannah Woodward, Patricia C. Salinas, Yuguang Zhao, E. Yvonne Jones
المصدر: Journal of Medicinal Chemistry. 63:12942-12956
مصطلحات موضوعية: 0303 health sciences, Reporter gene, animal structures, Carboxylesterase activity, Chemistry, Cell, Wnt signaling pathway, 01 natural sciences, Chemical space, Notum, 0104 chemical sciences, 3. Good health, Negative regulator, 010404 medicinal & biomolecular chemistry, 03 medical and health sciences, Crystallography, Carboxylesterase, medicine.anatomical_structure, Drug Discovery, medicine, Molecular Medicine, 030304 developmental biology
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المؤلفون: Nicky J. Willis, William Mahy, James Sipthorp, Yuguang Zhao, Hannah L. Woodward, Benjamin N. Atkinson, Elliott D. Bayle, Fredrik Svensson, Sarah Frew, Fiona Jeganathan, Amy Monaghan, Stefano Benvegnù, Sarah Jolly, Luca Vecchia, Reinis R. Ruza, Svend Kjær, Steven Howell, Ambrosius P. Snijders, Magda Bictash, Patricia C. Salinas, Jean-Paul Vincent, E. Yvonne Jones, Paul Whiting, Paul V. Fish
مصطلحات موضوعية: Model organisms, Chemical Biology & High Throughput, animal structures, FOS: Clinical medicine, Esterases, Neurosciences, Brain, Cell Biology, Crystallography, X-Ray, Biochemistry & Proteomics, Imaging, Signalling & Oncogenes, Drug Discovery, Molecular Medicine, Synthetic Biology, Enzyme Inhibitors, Wnt Signaling Pathway, Genetics & Genomics, Developmental Biology, Structural Biology & Biophysics, Computational & Systems Biology
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3474b8ac04a0b606e41a67edadf62c69