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1
المؤلفون: Paula Savage, Louis L. Martin, Suraj S. Shetty, Arco Y. Jeng
المصدر: International Journal of Peptide and Protein Research. 42:227-232
مصطلحات موضوعية: Male, Swine, Molecular Sequence Data, Cathepsin D, Peptide, Biochemistry, Substrate Specificity, chemistry.chemical_compound, Pepsin, Animals, Aspartic Acid Endopeptidases, Amino Acid Sequence, Chymosin, Protein Precursors, chemistry.chemical_classification, Chromatography, biology, Molecular mass, Chemistry, Endothelins, Fast atom bombardment, Enzyme, biology.protein, Rabbits, Protein Processing, Post-Translational, Pepstatin
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c8f6c90498222f9911bd96da61feda3
https://doi.org/10.1111/j.1399-3011.1993.tb00136.x -
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المؤلفون: Michael E. Beil, Arco Y. Jeng, Charles W. Bruseo, Angelo J. Trapani, Fariborz Firooznia, Paula Savage
المصدر: Journal of Cardiovascular Pharmacology. 44:S211-S215
مصطلحات موضوعية: Male, medicine.medical_specialty, Indoles, Time Factors, Endothelin converting enzyme 1, medicine.medical_treatment, Administration, Oral, Angiotensin-Converting Enzyme Inhibitors, Blood Pressure, CHO Cells, Endothelin-Converting Enzymes, Peptidyl-Dipeptidase A, Pharmacology, Transfection, Rats, Sprague-Dawley, Cricetulus, Atrial natriuretic peptide, Cricetinae, Internal medicine, Renin–angiotensin system, medicine, Animals, Aspartic Acid Endopeptidases, Humans, Prodrugs, Protease Inhibitors, education, Neprilysin, education.field_of_study, Endothelin-1, biology, Chemistry, Angiotensin II, Metalloendopeptidases, Angiotensin-converting enzyme, Dipeptides, Prodrug, Rats, Endocrinology, Injections, Intravenous, biology.protein, Rabbits, Diuretic, Cardiology and Cardiovascular Medicine, Atrial Natriuretic Factor
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fce19180c663a92a9de8fa97a727250c
https://doi.org/10.1097/01.fjc.0000166237.57077.d6 -
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المؤلفون: Masashi Yanagisawa, Raviraj Kulathila, Paula Savage, Arco Y. Jeng, Noriaki Emoto, Kirk Clark, Benjamin R. Bowen
المصدر: Clinical Science. 103:94S-97S
مصطلحات موضوعية: Insecta, Stereochemistry, Dimer, Genetic Vectors, Size-exclusion chromatography, Endothelin-Converting Enzymes, Sodium Chloride, Transfection, Cell Line, chemistry.chemical_compound, Column chromatography, Animals, Aspartic Acid Endopeptidases, Cloning, Molecular, Enzyme Inhibitors, Protein Precursors, Edetic Acid, Chromatography, Endothelin-1, biology, Chemistry, Endothelins, Phosphoramidon, Glycopeptides, Metalloendopeptidases, Substrate (chemistry), General Medicine, Hydrogen-Ion Concentration, Alkaline Phosphatase, Enzyme Activation, Isoenzymes, Monomer, Concanavalin A, biology.protein, Alkaline phosphatase, Cattle, Baculoviridae
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::896b333f413839bce2760d82ba30d935
https://doi.org/10.1042/cs103s094s -
4
المؤلفون: Paula Savage, Hoyer Denton W, Arco Y. Jeng, Cynthia A. Fink, Charles W. Bruseo, Angelo J. Trapani, Michael E. Beil
المصدر: Clinical Science. 103:102S-106S
مصطلحات موضوعية: Male, medicine.hormone, medicine.medical_specialty, Endothelin converting enzyme 1, Phenylalanine, Blood Pressure, Endothelin-Converting Enzymes, Pharmacology, Rats, Sprague-Dawley, Endothelins, Inhibitory Concentration 50, Atrial natriuretic peptide, Internal medicine, medicine, Animals, Aspartic Acid Endopeptidases, Sulfhydryl Compounds, Enzyme Inhibitors, Protein Precursors, education, education.field_of_study, Dose-Response Relationship, Drug, Endothelin-1, Chemistry, Area under the curve, Metalloendopeptidases, General Medicine, Endothelin 1, Peptide Fragments, Rats, Dose–response relationship, Endocrinology, Area Under Curve, Neprilysin, Omapatrilat, Endothelin receptor, Atrial Natriuretic Factor, medicine.drug
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::230c517f82ed2be07d2264ed58723f5b
https://doi.org/10.1042/cs103s102s -
5
المؤلفون: Paivi Jaana Kukkola, Suraj S. Shetty, Natalie A. Bilci, Paula Savage, Theodore Ikler, Arco Y. Jeng, Dominick DelGrande
المصدر: Bioorganic & Medicinal Chemistry Letters. 11:1737-1740
مصطلحات موضوعية: Endothelin Receptor Antagonists, Endothelin Antagonists, Indoles, Receptors, Endothelin, Stereochemistry, Chemistry, Organic Chemistry, Clinical Biochemistry, Pharmaceutical Science, Receptor, Endothelin A, Biochemistry, Endothelin A Receptor Antagonists, Drug Discovery, Benzene derivatives, Molecular Medicine, Pharmacophore, Endothelin receptor, Receptor, Molecular Biology
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المؤلفون: Nicholas Marcopoulos, Charles W. Bruseo, Candido Gude, Ying Qiao, Arco Y. Jeng, Cynthia A. Fink, Kenneth Chan, Paula Savage, Michael E. Beil, Angelo J. Trapani, Fariborz Firooznia, Yoshitaka Satoh
المصدر: Bioorganic & Medicinal Chemistry Letters. 11:375-378
مصطلحات موضوعية: Endothelin converting enzyme 1, Stereochemistry, Clinical Biochemistry, Pharmaceutical Science, Blood Pressure, Endothelin-Converting Enzymes, Biochemistry, Chemical synthesis, Inhibitory Concentration 50, Structure-Activity Relationship, chemistry.chemical_compound, Drug Discovery, Animals, Aspartic Acid Endopeptidases, Combinatorial Chemistry Techniques, Moiety, Prodrugs, Enzyme Inhibitors, education, Molecular Biology, chemistry.chemical_classification, education.field_of_study, Alanine, Dose-Response Relationship, Drug, biology, Drug Administration Routes, Biphenyl Compounds, Organic Chemistry, Metalloendopeptidases, Stereoisomerism, Biological activity, Prodrug, Amides, Rats, Enzyme, chemistry, Enzyme inhibitor, biology.protein, Molecular Medicine, Derivative (chemistry)
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المؤلفون: Paula Savage, Angelo J. Trapani, Arco Y. Jeng, Charles W. Bruseo, Mary Chou, S. De Lombaert, Michael E. Beil
المصدر: Life Sciences. 67:1025-1033
مصطلحات موضوعية: medicine.medical_specialty, education.field_of_study, Chemistry, Endothelin converting enzyme 1, General Medicine, Prodrug, Endothelin 1, General Biochemistry, Genetics and Molecular Biology, Endocrinology, Atrial natriuretic peptide, In vivo, Internal medicine, Renin–angiotensin system, medicine, General Pharmacology, Toxicology and Pharmaceutics, Endothelin receptor, education, Neprilysin
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المؤلفون: John Moliterni, Arco Y. Jeng, John Fitt, Lisa B. Stamford, Eli M. Wallace, L. Blanchard, Mary Chou, S. De Lombaert, Jenny Tan, Paula Savage, Daniel Hoyer, N. Marcopoulos, D. Simonsbergen, Angelo J. Trapani, Yoshitaka Satoh
المصدر: Journal of Medicinal Chemistry. 43:488-504
مصطلحات موضوعية: Male, medicine.hormone, Endothelin converting enzyme 1, Stereochemistry, Organophosphonates, Tetrazoles, Blood Pressure, Endothelin-Converting Enzymes, Rats, Sprague-Dawley, Endothelins, Structure-Activity Relationship, chemistry.chemical_compound, In vivo, Drug Discovery, medicine, Animals, Aspartic Acid Endopeptidases, Humans, Structure–activity relationship, Tetrazole, Enzyme Inhibitors, Protein Precursors, education, Benzofurans, education.field_of_study, Endothelin-1, biology, Phosphoramidon, Metalloendopeptidases, Stereoisomerism, Endothelin 1, Combinatorial chemistry, Rats, chemistry, Enzyme inhibitor, biology.protein, Molecular Medicine
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المؤلفون: Paula Savage, Angelo J. Trapani, Arco Y. Jeng, Stéphane De Lombaert, Charles W. Bruseo, Mary Chou, Michael E. Beil
المصدر: Journal of Cardiovascular Pharmacology. 36:S36-S39
مصطلحات موضوعية: Endothelin converting enzyme 1, Organophosphonates, Endothelin-Converting Enzymes, Pharmacology, Structure-Activity Relationship, In vivo, Animals, Aspartic Acid Endopeptidases, Humans, Protease Inhibitors, education, IC50, Benzofurans, education.field_of_study, biology, Chemistry, Metalloendopeptidases, Biological activity, Prodrug, Endothelin 1, Rats, Enzyme inhibitor, Drug Design, COS Cells, biology.protein, Endothelin receptor, Cardiology and Cardiovascular Medicine
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::632e009918428488e85e026ca96bfac6
https://doi.org/10.1097/00005344-200036001-00014 -
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المؤلفون: Mary Chou, Michael A. Moskal, Arco Y. Jeng, Nicholas Marcopulos, Eli M. Wallace, Alan D. Neubert, John Moliterni, Lisa B. Stamford, Angelo J. Trapani, Paula Savage
المصدر: Journal of Medicinal Chemistry. 41:1513-1523
مصطلحات موضوعية: Male, Stereochemistry, Endothelin converting enzyme 1, Molecular Sequence Data, Organophosphonates, Blood Pressure, Peptide, CHO Cells, Tripeptide, Endothelin-Converting Enzymes, Rats, Sprague-Dawley, Structure-Activity Relationship, chemistry.chemical_compound, Cricetinae, Amide, Drug Discovery, Peptide synthesis, Animals, Aspartic Acid Endopeptidases, Humans, Amino Acid Sequence, Enzyme Inhibitors, education, Peptide sequence, chemistry.chemical_classification, education.field_of_study, Dipeptide, Endothelin-1, Acetylene, Metalloendopeptidases, Phosphonate, Recombinant Proteins, Rats, chemistry, Drug Design, Molecular Medicine, Neprilysin