المؤلفون: Heshan Peiris, Michael D Duffield, Joao Fadista, Claire F Jessup, Vinder Kashmir, Amanda J Genders, Sean L McGee, Alyce M Martin, Madiha Saiedi, Nicholas Morton, Roderick Carter, Michael A Cousin, Alexandros C Kokotos, Nikolay Oskolkov, Petr Volkov, Tertius A Hough, Elizabeth M C Fisher, Victor L J Tybulewicz, Jorge Busciglio, Pinar E Coskun, Ann Becker, Pavel V Belichenko, William C Mobley, Michael T Ryan, Jeng Yie Chan, D Ross Laybutt, P Toby Coates, Sijun Yang, Charlotte Ling, Leif Groop, Melanie A Pritchard, Damien J Keating

المصدر: PLoS Genetics, Vol 12, Iss 5, p e1006033 (2016)

مصطلحات موضوعية: Genetics, QH426-470

وصف الملف: electronic resource

Relation: https://doaj.org/toc/1553-7390; https://doaj.org/toc/1553-7404

URL الوصول: https://doaj.org/article/55d1108814ad40e3b162e4623311cfe8

المؤلفون: Pavel V Belichenko, Rime Madani, Lorianne Rey-Bellet, Maria Pihlgren, Ann Becker, Adeline Plassard, Stephanie Vuillermot, Valérie Giriens, Rachel L Nosheny, Alexander M Kleschevnikov, Janice S Valletta, Sara K S Bengtsson, Gordon R Linke, Michael T Maloney, David T Hickman, Pedro Reis, Anne Granet, Dorin Mlaki, Maria Pilar Lopez-Deber, Long Do, Nishant Singhal, Eliezer Masliah, Matthew L Pearn, Andrea Pfeifer, Andreas Muhs, William C Mobley

المصدر: PLoS ONE, Vol 11, Iss 3, p e0152471 (2016)

مصطلحات موضوعية: Medicine, Science

وصف الملف: electronic resource

Relation: http://europepmc.org/articles/PMC4811554?pdf=render; https://doaj.org/toc/1932-6203

URL الوصول: https://doaj.org/article/e6e5615e619c41a0ad64eafb049c71c7

المؤلفون: Pavel V Belichenko, Alexander M Kleschevnikov, Ann Becker, Grant E Wagner, Larisa V Lysenko, Y Eugene Yu, William C Mobley

المصدر: PLoS ONE, Vol 10, Iss 7, p e0134861 (2015)

مصطلحات موضوعية: Medicine, Science

وصف الملف: electronic resource

Relation: http://europepmc.org/articles/PMC4521889?pdf=render; https://doaj.org/toc/1932-6203

URL الوصول: https://doaj.org/article/d51c038fdc8148899fbd97c4cd544d85

المؤلفون: Sarah Wie, Alexander M. Kleschevnikov, William C. Mobley, Kai Meng, Zhuo Xing, Tao Yu, Xiaoling Jiang, Annie Pao, Y. Eugene Yu, Pavel V. Belichenko, Li Zhang, Chunhong Liu, Jennifer Peresie

المصدر: Human Molecular Genetics. 24:6540-6551

مصطلحات موضوعية: Down syndrome, DYRK1A, Mutant, Biology, medicine.disease_cause, Mice, Chromosome 16, Gene duplication, Genetics, medicine, Animals, Humans, Molecular Biology, Genetic Association Studies, Genetics (clinical), Sequence Deletion, Mutation, Articles, General Medicine, medicine.disease, Mice, Mutant Strains, Disease Models, Animal, Chromosome Deletion, Down Syndrome, Cognition Disorders, Trisomy, Chromosome 21

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bbe27eb20fecd99f8934be85b8c3306d
https://doi.org/10.1093/hmg/ddv364

المؤلفون: Pinar Coskun, Damien J. Keating, Michael D. Duffield, Claire F. Jessup, William C. Mobley, Sean L. McGee, Victor L. J. Tybulewicz, Tertius Hough, Pavel V. Belichenko, João Fadista, Amanda J Genders, Penelope Coates, Melanie April Pritchard, Jorge Busciglio, Ann Becker, Elizabeth M. C. Fisher, Heshan Peiris, Ross Laybutt

المصدر: Diabetes. 64:A1-A100

مصطلحات موضوعية: geography, Down syndrome, geography.geographical_feature_category, Endocrinology, Diabetes and Metabolism, Immunology, Internal Medicine, Cancer research, medicine, Biology, Islet, medicine.disease, Gene, S cell

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::4f65b4c60e947939cc727eec0c380290
https://doi.org/10.2337/db15-1-385

المؤلفون: Ahmad Salehi, Rachel L. Nosheny, Van Dang, Atoossa Fahimi, B.L. Busse, April M. Weissmiller, Pavel V. Belichenko, Devsmita Das, William C. Mobley, S.J. Smith

المصدر: Neurobiology of Disease, Vol 77, Iss, Pp 173-190 (2015)

مصطلحات موضوعية: Male, Aging, Messenger, Tropomyosin receptor kinase B, Neurodegenerative, Alzheimer's Disease, Transgenic, Synapse, Mice, 2.1 Biological and endogenous factors, Aetiology, Cerebral Cortex, Regulation of gene expression, musculoskeletal, neural, and ocular physiology, TrkB, medicine.anatomical_structure, Neurology, Cerebral cortex, Neurological, Signal transduction, Receptor, Signal Transduction, Intellectual and Developmental Disabilities (IDD), Clinical Sciences, Green Fluorescent Proteins, Signaling endosomes, Mice, Transgenic, Neuropathology, Biology, Article, lcsh:RC321-571, Behavioral and Social Science, Acquired Cognitive Impairment, medicine, Animals, Humans, Receptor, trkB, RNA, Messenger, lcsh:Neurosciences. Biological psychiatry. Neuropsychiatry, Brain-derived neurotrophic factor, Neurology & Neurosurgery, Animal, Brain-Derived Neurotrophic Factor, Neurosciences, Alzheimer's Disease including Alzheimer's Disease Related Dementias (AD/ADRD), Colocalization, Brain Disorders, Disease Models, Animal, Ts65Dn mice, BDNF, Gene Expression Regulation, nervous system, Disease Models, Synapses, RNA, Dementia, Down Syndrome, Neuroscience, Synaptosomes

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e7fe02518302c95f958cb42c1fc95341
https://doi.org/10.1016/j.nbd.2015.02.022

المؤلفون: Ann Becker, Pinar Coskun, Petr Volkov, Vinder Kashmir, Nikolay Oskolkov, Claire F. Jessup, Heshan Peiris, Michael T. Ryan, William C. Mobley, Amanda J Genders, Nicholas M. Morton, Alyce M. Martin, D. Ross Laybutt, Michael D. Duffield, Michael A. Cousin, João Fadista, Jeng Yie Chan, Sean L. McGee, Leif Groop, Alexandros C. Kokotos, Victor L. J. Tybulewicz, Tertius Hough, Elizabeth M. C. Fisher, Melanie April Pritchard, Jorge Busciglio, P. Toby Coates, Roderick N. Carter, Charlotte Ling, Madiha Saiedi, Sijun Yang, Pavel V. Belichenko, Damien J. Keating

المصدر: Peiris, H; Duffield, MD; Fadista, J; Jessup, CF; Kashmir, V; Genders, AJ; et al.(2016). A Syntenic Cross Species Aneuploidy Genetic Screen Links RCAN1 Expression to β-Cell Mitochondrial Dysfunction in Type 2 Diabetes. PLoS Genetics, 12(5). doi: 10.1371/journal.pgen.1006033. UC Irvine: Retrieved from: http://www.escholarship.org/uc/item/69g1d108
Peiris, H, Duffield, M D, Fadista, J, Jessup, C F, Kashmir, V, Genders, A J, McGee, S L, Martin, A M, Saiedi, M, Morton, N, Carter, R, Cousin, M A, Kokotos, A, Oskolkov, N, Volkov, P, Hough, T A, Fisher, E M C, Tybulewicz, V L J, Busciglio, J, Coskun, P E, Becker, A, Belichenko, P V, Mobley, W C, Ryan, M T, Chan, J Y, Laybutt, D R, Coates, P T, Yang, S, Ling, C, Groop, L, Pritchard, M A & Keating, D J 2016, ' A syntenic cross species aneuploidy genetic screen links RCAN1 expression to β-cell mitochondrial dysfunction in Type 2 diabetes ', PLoS Genetics . https://doi.org/10.1371/journal.pgen.1006033
PLoS Genetics, Vol 12, Iss 5, p e1006033 (2016)
PLoS Genetics

مصطلحات موضوعية: 0301 basic medicine, Cancer Research, Candidate gene, endocrine system diseases, Physiology, Chromosomes, Human, Pair 21, medicine.medical_treatment, Cell Membranes, Muscle Proteins, Mitochondrion, QH426-470, Biochemistry, Mice, In-vitro, 0302 clinical medicine, Endocrinology, Adenosine Triphosphate, Insulin-Secreting Cells, Insulin Secretion, Medicine and Health Sciences, Glucose homeostasis, Insulin, Genetics (clinical), Energy-Producing Organelles, Regulation of gene expression, Genetics & Heredity, DNA methylation, Organic Compounds, Monosaccharides, Intracellular Signaling Peptides and Proteins, Animal Models, Chromatin, Mitochondria, Nucleic acids, Chemistry, Physical Sciences, Epigenetics, Cellular Structures and Organelles, DNA modification, Life Sciences & Biomedicine, Chromatin modification, Research Article, Chromosome biology, medicine.medical_specialty, Human pancreatic-islets, Carbohydrates, Mouse Models, Biology, Bioenergetics, Research and Analysis Methods, 03 medical and health sciences, Insulin resistance, Model Organisms, Internal medicine, medicine, Genetics, Animals, Humans, DSCR1, Molecular Biology, Ecology, Evolution, Behavior and Systematics, Metaolism, Diabetic Endocrinology, Science & Technology, Endocrine Physiology, Protein, Organic Chemistry, Calcium-Binding Proteins, Chemical Compounds, Biology and Life Sciences, Cell Biology, DNA, medicine.disease, Aneuploidy, Hormones, Down-syndrome, 030104 developmental biology, Glucose, Diabetes Mellitus, Type 2, Gene Expression Regulation, Oxidative stress, Hyperglycemia, Protein Biosynthesis, Sydrome critical region, Gene expression, Down Syndrome, Chromosome 21, 030217 neurology & neurosurgery, Genetic screen, Model, Developmental Biology

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b8a79e00f46b9b13910b1e47b75ca457
http://www.escholarship.org/uc/item/69g1d108

المؤلفون: Ann Becker, Lorianne Rey-Bellet, Andrea Pfeifer, Michael T. Maloney, Pavel V. Belichenko, Anne Granet, Dorin Mlaki, Valérie Giriens, Sara K. Bengtsson, David T. Hickman, Andreas Muhs, Rime Madani, Adeline Plassard, Nishant Singhal, Rachel L. Nosheny, Maria Pihlgren, Long Do, Stephanie Vuillermot, Gordon R. Linke, Matthew L. Pearn, Janice S. Valletta, William C. Mobley, Pedro Reis, María Pilar López-Deber, Alexander M. Kleschevnikov, Eliezer Masliah

المساهمون: Herault, Yann

المصدر: PLoS ONE
PloS one, vol 11, iss 3
PLoS ONE, Vol 11, Iss 3, p e0152471 (2016)

مصطلحات موضوعية: Male, Aging, medicine.medical_treatment, Alzheimer's Disease, Biochemistry, Transgenic, Mice, 0302 clinical medicine, Amyloid precursor protein, Public and Occupational Health, Aetiology, Enzyme-Linked Immunoassays, lcsh:Science, Mammals, Basal forebrain, Behavior, Animal, Vaccination, Brain, Cholinergic Neurons, 3. Good health, Blood, Neurology, Amyloid, Intellectual and Developmental Disabilities (IDD), Immunology, Hemorrhage, 03 medical and health sciences, Alzheimer Disease, Memory, Cholinergic neuron, Immunoassays, Behavior, Animal, lcsh:R, Organisms, Biology and Life Sciences, Proteins, medicine.disease, Prevention of disease and conditions, 030104 developmental biology, lcsh:Q, Dementia, Preventive Medicine, Atrophy, Down Syndrome, Cognition Disorders, 030217 neurology & neurosurgery, Biomarkers, 0301 basic medicine, and promotion of well-being, Physiology, lcsh:Medicine, Monophosphoryl Lipid A, Neurodegenerative, Immune Physiology, Medicine and Health Sciences, 2.1 Biological and endogenous factors, Vaccines, Multidisciplinary, Immune System Proteins, biology, Neurodegenerative Diseases, Animal Models, Hematology, Vaccination and Immunization, Body Fluids, 3.4 Vaccines, Neurological, Vertebrates, Anatomy, Adjuvant, Research Article, Down syndrome, General Science & Technology, Mouse Models, Mice, Transgenic, Research and Analysis Methods, Rodents, Antibodies, Blood Plasma, Vaccine Related, Model Organisms, mental disorders, Mental Health and Psychiatry, medicine, Acquired Cognitive Impairment, Animals, Inflammation, Amyloid beta-Peptides, business.industry, Neurosciences, Alzheimer's Disease including Alzheimer's Disease Related Dementias (AD/ADRD), Newborn, Brain Disorders, Disease Models, Animal, Good Health and Well Being, Animals, Newborn, Gene Expression Regulation, Disease Models, Amniotes, biology.protein, Immunologic Techniques, Immunization, Septal Nuclei, business

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0dfba69d0dfcfb75e94cc602c199ebe4
http://europepmc.org/articles/PMC4811554

المؤلفون: Khin Htun, Mehrdad Faizi, Lucia F. Jacobs, Mehrdad Shamloo, Pavel V. Belichenko, William C. Mobley, Alexander M. Kleschevnikov

المصدر: Journal of Neuroscience. 32:9217-9227

مصطلحات موضوعية: Male, medicine.medical_specialty, medicine.drug_class, GABA-B Receptor Antagonists, Mice, Transgenic, Hippocampal formation, Neurotransmission, Synaptic Transmission, Article, Mice, Organ Culture Techniques, Internal medicine, Genetic model, medicine, Animals, Mice, Inbred C3H, Neuronal Plasticity, General Neuroscience, Neural Inhibition, Long-term potentiation, Receptor antagonist, Mice, Inbred C57BL, Disease Models, Animal, Endocrinology, nervous system, Synaptic plasticity, NMDA receptor, Female, Down Syndrome, Cognition Disorders, Psychology, Neuroscience

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f54c918bbe3060ecff82dc9a96f76a8
https://doi.org/10.1523/jneurosci.1673-12.2012

المؤلفون: Nay Saw, William C. Mobley, Matthew Priestley, Christine Tun, Patrick Bader, Mehrdad Faizi, Pavel V. Belichenko, Richard W. Tsien, Mehrdad Shamloo, Alexander M. Kleschevnikov, Angelo Encarnacion

المصدر: Neurobiology of Disease, Vol 43, Iss 2, Pp 397-413 (2011)

مصطلحات موضوعية: Male, Xamoterol, Hippocampus, Mice, Transgenic, Water maze, Social interaction, Article, lcsh:RC321-571, Mice, Norepinephrine, chemistry.chemical_compound, Memory, Genetic model, medicine, Ts65Dn mouse, Animals, Fear conditioning, lcsh:Neurosciences. Biological psychiatry. Neuropsychiatry, Nootropic Agents, Cognitive deficit, Behavior, Behavior, Animal, Spontaneous alternation, Symptomatic relief, Mice, Mutant Strains, Disease Models, Animal, Phenotype, nervous system, Neurology, chemistry, Female, Down Syndrome, Receptors, Adrenergic, beta-1, medicine.symptom, Cognition Disorders, Psychology, Neuroscience

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::36701621f210425e8359dd4eabaf0810
https://doi.org/10.1016/j.nbd.2011.04.011